Clinical trials: Pancreas Inflamed
Pancreatitis
Precise Endoscopic Application of Nitroglycerin in Preventing Post-ERCP Pancreatitis
Endoscopic retrograde cholangiopancreatography (ERCP) is a technically demanding procedure combining endoscopy and fluoroscopy to diagnose and treat pancreaticobiliary disorders such as bile duct stones, strictures, and…
- Trial name
- NCT07083063
- Testing
- Nitroglycerin (NTG), Normal Saline (0.9% NaCl)
- Where
- Taiwan
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Post-ERCP Acute Pancreatitis
Short-term Intravenous Fluids for Prevention of Post-ERCP Pancreatitis
This study will explore the efficacies of several practical short-term (peri-procedural) intravenous fluid regimens in the prevention of post- endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP).
- Trial name
- STRIPE (NCT06260878)
- Testing
- Intravenous Ringer's lactate
- Where
- Canada
- Volunteers
- 505 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Acute Pancreatitis
Exploring the Mechanism of Severe Acute Pancreatitis Based on Metagenomics, Metabolomics and Proteomics
The goal of this observational study is to learn about the biomarkers and mechanisms of severe acute pancreatitis in 30 healthy controls, 30 patients of mild acute pancreatitis, 30 patients of moderately severe acute…
- Trial name
- NCT06230432
- Where
- China
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Nanchang University
Post-ERCP Acute Pancreatitis
A Prospective Trial of Aggressive Hydration Strategy to Reduce Post-ERCP Pancreatitis
Postendoscopic retrograde cholangiopancreatography pancreatitis is the most frequent and serious complication of ERCP procedures, occurring in approximately 5-15% of unselected patients.
- Trial name
- NCT02308891
- Testing
- lactated Ringer's solution (vigorous hydration arm), lactated Ringer's solution (standard hydration arm), endoscopic retrograde cholangiopancreatography (ERCP)
- Where
- 3 sites in South Korea
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- Dankook University
Oral Microbiota, Pancreatitis
The Characteristics of Oral Microbiota in Chronic Pancreatitis and Autoimmune Pancreatitis
There are more than 700 different bacteria colonized in human oral cavity, which are collectively referred to as oral microbiota.
- Conditions
- Oral Microbiota, Pancreatitis, Pancreatic Cancer
- Trial name
- NCT07015580
- Testing
- 16S rRNA sequencing
- Where
- China
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Pancreatic Exocrine Insufficiency
The Development of a Metabolomic Test to Diagnose and Quantify Pancreatic Exocrine Insufficiency (The DETECTION Study)
DETECTION. The development of a metabolomic test to diagnose and quantify pancreatic exocrine insufficiency.
- Trial name
- DETECTION (NCT05980221)
- Testing
- Metabolomics, 13C MTGT
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital Birmingham NHS Foundation Trust
Acute Pancreatitis
Ketorolac in Acute Pancreatitis
This study will compare pain management strategies for patients hospitalized with acute pancreatitis. Standard of care pain management will be compared to standard of care plus intravenous ketorolac.
- Trial name
- NCT04282200
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Cystic Fibrosis
Non-Invasive Biomarkers in Cystic Fibrosis
Background Chronic airway inflammation is present in cystic fibrosis. Non-invasive inflammometry may be useful in disease management.
- Trial name
- NCT00413140
- Where
- 4 sites in Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Acute Pancreatitis, 2019 Novel Coronavirus Infection
Study and Analysis of Acute Pancreatitis Complicated With COVID-19
The goal of this observational study was to explore the complex relationship between changes in the intestinal microbiome and serum metabolites in patients with novel coronavirus infection and acute pancreatitis.
- Trial name
- NCT05722678
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Yuansong Sun
Pancreatitis, Diet, Food, and Nutrition
Regular vs. Clear Liquid Diet for Mild to Moderate Acute Pancreatitis
Acute pancreatitis is among the most common gastroenterology diagnosis in the United States, and represents a large economic burden to the United States health system.
- Conditions
- Pancreatitis, Diet, Food, and Nutrition, Diet, Pancreatic Disease
- Trial name
- NCT04932785
- Testing
- Regular diet, Clear Liquid Diet
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Post-ERCP Acute Pancreatitis
Somatostatin, Octreotide, Pentoxyfilline in the Prevention of Post-ERCP Pancreatitis and Molecular Markers
Octreotide, somatostatin and pentoxyfilline commercially available drugs that are used in various clinical situations. They are safe and known for years.
- Trial name
- NCT00222092
- Where
- Greece
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Ioannina
Chronic Pancreatitis
Pain Phenotypes in Chronic Pancreatitis
Chronic pancreatitis (CP) is characterised by recurrent abdominal pain. The pathological hallmarks of CP is pancreatic stellate cell activation that results in persistent inflammation and progressive fibrosis.
- Trial name
- PIP (NCT05713344)
- Testing
- Clinical history, Clinical examination, Evaluation of quality of life
- Where
- India
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Pancreatitis
Genetic Analysis for Predicting of Relapse During Steroid Treatment for Autoimmune Pancreatitis (AIP)
To determine whether certain alleles or haplotypes of major histocompatibility complex gene are associated with AIP in Korean population, we undertook this study with high-resolution typing for HLA (sequence-based typing).
- Trial name
- NCT00444444
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Ascites, Blunt Abdominal Trauma
Telesonography Adaptation and Use to Improve the Standard of Patient Care Within a Dominican Community
The role of teleradiology has far reaching implications for the health of remote and underserved populations. The ability to coordinate radiographic evaluation and diagnosis from a distance has the potential to raise the standard…
- Conditions
- Ascites, Blunt Abdominal Trauma, Cholelithiasis, Cholecystitis
- Trial name
- NCT00591968
- Testing
- SonoSite Titan portable ultrasound coupled with email telediagnosis
- Where
- Dominican Republic
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Edward Via Virginia College of Osteopathic Medicine
Asthma, Cystic Fibrosis
Standardisation of Measurements in Exhaled Breath and Exhaled Breath Condensate.
Background: in various pediatric pulmonary diseases such as asthma, cystic fibrosis or bronchopulmonary dysplasia an increased inflammation is present.
- Conditions
- Asthma, Cystic Fibrosis, Chronic Lung Disease, Pneumonia
- Trial name
- NCT00983671
- Where
- Netherlands
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Cholelithiasis Associated With Common Bile Duct Stones
Timing of Laparoscopic Cholecystectomy After Endoscopic Retrograde Cholangiography for Acute Biliary Pancreatitis
Timing of laparoscopic cholecystectomy following after endoscopic retrograde cholangiography for acute biliary pancreatitis is a controversial issue.
- Trial name
- NCT01687959
- Testing
- tissue sampling from peritoneum of the gallbladder
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Pancreatic Neoplasms, CHRONIC PANCREATITIS
Needle-based Confocal Endomicroscopy Examination of Pancreatic Masse
Introduction: Pancreatic cancer is one of the most aggressive malignancies with only 5% of patients being alive at five years. EUS (endoscopic ultra sound) is an established, sensitive diagnostic tool in pancreatic cancer and for…
- Trial name
- NCT01734967
- Testing
- needle based CLE, EUS-FNA
- Where
- 2 sites in Denmark, Romania
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Coronary Artery Disease, Congestive Heart Failure
Prognostic Indicators as Provided by the EPIC ClearView
The objective of this study is to determine whether the finger tip images captured by the EPIC ClearView device, when analyzed via the ClearView software, produce a Response Scale that characterizes trends consistent with known…
- Conditions
- Coronary Artery Disease, Congestive Heart Failure, Valvular Heart Disease, Atrial Fibrillation
- Trial name
- GBMC (NCT01476995)
- Where
- United States
- Volunteers
- 353 people, healthy volunteers welcome
- Sponsor
- Epic Research & Diagnostics, Inc.
Diabetes Mellitus, Type 2, PreDiabetes
Blood Markers of Early Pancreas Cancer
Identifying biomarkers of early pancreatic ductal adenocarcinoma (PDAC) could facilitate screening for individuals at higher than average risk and expedite the diagnosis in individuals with symptoms and substantially improve an…
- Conditions
- Diabetes Mellitus, Type 2, PreDiabetes, Pancreas Cyst, Chronic Pancreatitis
- Trial name
- NCT03568630
- Where
- United States
- Volunteers
- 1,250 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Chronic Pancreatitis, Respiratory Insufficiency
Is There an Association Between Chronic Pancreatitis and Pulmonary Function
To evaluate pulmonary function in chronic pancreatitis compared with healthy volunteers and patients with cirrhosis.
- Conditions
- Chronic Pancreatitis, Respiratory Insufficiency, Cirrhosis, Liver, Lung Function Decreased
- Trial name
- RespPanc (NCT03850977)
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Hvidovre