Clinical trials: Pancreaticoduodenectomy
Pancreatic Cancer, Bile Duct Cancer
The Comparison of Miniinvasive and Open Pancreaticoduodenectomy for Cancer Pancreaticobiliary Zone
The Comparison of Miniinvasive and Open Pancreaticoduodenectomy for Cancer Pancreaticobiliary Zone
- Conditions
- Pancreatic Cancer, Bile Duct Cancer, Ampulla of Vater Cancer
- Trial name
- NCT04763642
- Testing
- pancreaticoduodenectomy
- Where
- Russia
- Volunteers
- 320 people
- Sponsor
- State Budget Public Health Institution Scientific Research Institute - Ochapovsky Regional Clinical Hospital
Surgical Technique
Impact of Side to Side Gastrojejunostomy on the Rate of Delayed Gastric Emptying After Pancreaticoduodenectomy (IPAD)
Prospective bi-centric randomized open-label study comparing side to side and end to side gastrojejunostomy in pancreaticoduodenectomy
- Trial name
- IPAD (NCT04742166)
- Testing
- Reconstruction
- Where
- 2 sites in France
- Volunteers
- 166 people
- Sponsor
- Rennes University Hospital
Postoperative Acute Pancreatitis, Pancreaticoduodenectomy
Clinical and Economic Validation of the ISGPS Definition of PPAP
This prospective validation study aims to investigate the incidence of PPAP after pancreaticoduodenectomy (PD) by applying the ISGPS definition and grading system, to demonstrate its clinical impact by examining associated…
- Conditions
- Postoperative Acute Pancreatitis, Pancreaticoduodenectomy, Postoperative Pancreatic Fistula, Postoperative Complications
- Trial name
- ISGPS-PPAP (NCT05680623)
- Testing
- PPAP diagnosis
- Where
- Italy
- Volunteers
- 2,900 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Pancreaticoduodenectomy, Malnutrition
Enteral vs. Oral Nutrition After Pancreatoduodenectomy
Patients suffering from pancreas cancer as well as patients with chronic pancreatitis or requiring pancreas surgery often are in a compromised nutritional status.
- Conditions
- Pancreaticoduodenectomy, Malnutrition, Postoperative Complications
- Trial name
- NUTRIWHI (NCT05042882)
- Testing
- Early enteral nutrition
- Where
- 3 sites in France, Switzerland
- Volunteers
- 144 people
- Sponsor
- University of Lausanne Hospitals
Surgical Site Infection, Pancreaticoduodenectomy
Association of Cephalosporin Resistance and Surgical Site Infections in Patients Undergoing Pancreaticoduodenectomy
Preoperative biliary drainage predisposes the bile to be contaminated with bacteria of the duodenum. These bacteria colonizing the bile are a potential source for surgical site infections after pancreaticoduodenectomy and many…
- Conditions
- Surgical Site Infection, Pancreaticoduodenectomy, Biliary Tract Infection Bacterial
- Trial name
- NCT05581017
- Testing
- Preoperative biliary drainage
- Where
- Finland
- Volunteers
- 376 people
- Sponsor
- Helsinki University Central Hospital
Postoperative Pancreatic Fistula
A Study on the Occurrence Time of Grade-B Pancreatic Fistula After Pancreatoduodenectomy
To confirm the time point of CR-POPF of grade-B that patients with biochemical leak after PD or LPD turned into.
- Trial name
- NCT05667272
- Testing
- No intervention
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Changzhou Second People's Hospital affiliated with Nanjing Medical University
Pancreatic Neoplasms, Pancreatic Fistula
Preoperative EUS Elastography for Pancreatic Texture and POPF Prediction After PD
This prospective study evaluates whether preoperative endoscopic ultrasound elastography (EUS-E) can predict pancreatic texture during surgery and risk of postoperative pancreatic fistula (POPF) in 100 patients undergoing…
- Trial name
- EUS-E (NCT07139236)
- Testing
- Preoperative Endoscopic Ultrasound Elastography (EUS Elastography)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Minia University
Postoperative Fistula, Complications of Surgical and Medical Care: General Terms
External Drainage Versus Internal Drainage of Pancreatic Duct With a Stent After Pancreaticoduodenectomy (EDIDPD)
Postoperative pancreatic fistula (POPF) and other surgical complications are common after pancreatoduodenectomy (PD) and POPF is a major complication.
- Trial name
- EDIDPD (NCT01634971)
- Testing
- Internal Drainage of Pancreatic Duct after pancreatomy
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Pancreatic Cancer Resectable
Conventional Partial Pancreatoduodenectomy Versus an Extended Pancreatoduodenectomy for Pancreatic Head Cancers
The goal of this clinical trial is to learn if traditional pancreaticoduodenectomy (PD) combined with TRIANGLE (extended PD surgery) can increase disease-free survival (DFS) in patients with pancreatic head cancers compared to…
- Trial name
- NCT06703905
- Testing
- Expanded pancreaticoduodenectomy surgery, Pancreaticoduodenectomy
- Volunteers
- 270 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Auricular Acupoint Embedding, Pancreaticoduodenectomy
Ear Acupuncture Preventing Delayed Gastric Emptying.
Pancreatoduodenectomy is the preferred surgical method for periampullary diseases. The most common complication is gastric emptying disorder, which often greatly affects the quality of life of patients and prolongs the length of…
- Conditions
- Auricular Acupoint Embedding, Pancreaticoduodenectomy, Delayed Gastric Emptying
- Trial name
- NCT04118881
- Testing
- Ear Acupuncture
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Surgical Wound Infection, Pancreatic Neoplasms
The Use of Wound Protector in Whipple's Procedure With Intrabiliary Stent
Background: There are no published studies regarding the use of wound protectors in the context of surgical site infection (SSI) rates among patients receiving a pancreatoduodenectomy (Whipple) with preoperatively placed…
- Trial name
- NCT01836237
- Testing
- Alexis - a wound protector
- Where
- Canada
- Volunteers
- 107 people
- Sponsor
- University of Calgary
Pancreatic Neoplasm
Evaluation of Difficulty Score for Robotic Pancreatoduodenectomy
Robotic pancreatoduodenectomy is the most complex surgery for a general surgeon and consequently a pancreatic surgeon can aspire to.
- Trial name
- NCT04662346
- Testing
- Difficulty score system for robotic pancreatoduodenectomy
- Where
- 2 sites in Italy
- Volunteers
- 1,000 people
- Sponsor
- University of Pisa
Delayed Gastric Emptying
The Effect of taVNS on the Prognosis of Patients Undergoing Pancreatoduodenectomy
To explore the effects of transcutaneous auricular vagus nerve stimulation (taVNS) during the perioperative period on the incidence of delayed gastric emptying after pancreatoduodenectomy and its possible mechanisms.
- Trial name
- NCT06786923
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulator
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Affiliated Hospital of Nantong University
Pancreatic Cancer, Pancreatic Anastomotic Leak
Pancreaticogastrostomy Versus Pancreaticojejunostomy in Reconstruction After Cephalic Duodenopancreatectomy
Pancreaticoduodenectomy is the standards surgical procedure for various malignant and benign disease of the pancreas and periampullariy region.
- Trial name
- PanAm (NCT01324856)
- Testing
- Pancreatico gastro anastomosis, Pancreaticojejuno anastomosis
- Where
- 4 sites in Serbia
- Volunteers
- 100 people
- Sponsor
- University of Belgrade
Pancreatic Fistula, Pancreaticoduodenal; Fistula
Peritoneal Lavage on the Incidence of Pancreatic Fistula and Related Complications After Pancreatoduodenectomy
As one of the possible strategies to prevent pancreatic fistula, peritoneal lavage is still widely used in clinical practice, but it lacks more evidence of evidence-based medicine and recommendations of guidelines.
- Trial name
- NCT05657366
- Testing
- Peritoneal lavage
- Where
- China
- Volunteers
- 260 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Pancreatic Neoplasms, Pancreaticoduodenectomy
Benchmarking Outcomes in Pancreatic Surgery - WhippleBenchmarks.Org
The WhippleBenchmark 2 Collaborative study aims at defining benchmark criteria for best achievable outcomes after pancreaticoduodenectomy with portal vein resection.
- Trial name
- NCT04053998
- Testing
- Pancreaticoduodenectomy with portal vein resection
- Where
- 2 sites in Spain, United Kingdom
- Volunteers
- 1,462 people
- Sponsor
- Royal Free Hospital NHS Foundation Trust
Pancreatic Fistula, Pancreatic Neoplasms
Treatment of the Pancreatic Stump With Neoprene®-Based Glue After High-risk Pancreatoduodenectomy
The study evaluates the safety and efficacy of Neoprene-based glue in the management of pancreatic stump after pancreatoduodenectomy (PD) in patients at high risk for pancreatic fistula and early neoplastic recurrence, compared…
- Conditions
- Pancreatic Fistula, Pancreatic Neoplasms, Postoperative Complications
- Trial name
- NCT03738787
- Testing
- Pancreatic duct occlusion with Neoprene, Pancreato-Jejunal anastomosis
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Pancreas Cancer
Preoperative CA 19.9 Level Predicts Lymph Node Metastasis in Resectable Adenocarcinoma of the Head of the Pancreas.
In our multicenter retrospective study, preoperative CA 19.9 levels predicts the presence of lymph node metastasis at final histology in patients underwent pancreatoduodenectomy for pancreatic ductal adenocarcinoma .
- Trial name
- ICALYRA (NCT05959213)
- Volunteers
- 2,034 people
- Sponsor
- Fondazione Policlinico Universitario Campus Bio-Medico
Pancreaticoduodenectomy
Comparison of Hemodynamic Effects of Two Colloid Therapies in Post-operative Patients Undergoing Pancreaticoduodenectomy
From postoperative patients having undergone pancreaticoduodenectomy; 1. To compare the hemodynamic parameters from the patient administrated 5% HA and 6% Voluven 2.
- Trial name
- NCT01758172
- Testing
- 6% hydroxyethyl starch 130/0.4, Albumin
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Asan Medical Center
Pancreatic Cancer, Pancreatic Neoplasms
Monitoring of patIents With Microdialysis Following Pancreaticoduodenectomy
A pancreaticoduodenectomy is performed in patient with pancreatic cancer. The most common and serious complication is leakage between the intestine and the remnant pancreas after this procedure. It occurs in 20-30%.
- Conditions
- Pancreatic Cancer, Pancreatic Neoplasms, Biliary Tract Cancer, Duodenal Cancer
- Trial name
- MINIMUM (NCT03631173)
- Testing
- Surgical og radiological intervention, antibiotics
- Where
- Norway
- Volunteers
- 201 people
- Sponsor
- Oslo University Hospital