Clinical trials: Pandemic
Influenza
T-cell And General Immune Response to Seasonal Influenza Vaccine (SLVP018) Year 4, 2012
This study will investigate markers, mechanisms and define general predictors for immunological health by comparing influenza vaccine responses in monozygotic and dizygotic twins.
- Trial name
- NCT03022435
- Testing
- TIV, High-Dose TIV, LAIV
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Stanford University
COVID-19 Pandemic
Oral Neutralizing Antibody Booster for Post-vaccinated People With COVID19 Vaccine
This is a study trial to assess the effectiveness of the immune response stimulated by the genetically engineered Bacillus subtilis spore extract which contain Spike protein of the SARS-COV2 on the spore coat.
- Trial name
- NCT05158855
- Testing
- Bacillus subtilis spore extract
- Where
- Macau
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- DreamTec Research Limited
Covid19
Experience of an Emergency Intensive Care Unit During COVID-19 Pandemic
COVID-19, which emerged in China in December 2019, has become a pandemic with its spread to many countries of the world. Emergency departments also carried out an important part of the fight against pandemics in our…
- Trial name
- NCT04480060
- Testing
- COVID-19 diagnostic PCR
- Where
- Turkey (Türkiye)
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Prepandemic Influenza Vaccine
Safety and Immunogenicity of Two Doses of Monovalent Inactivated Influenza Vaccine That is Adjuvanted With MF59C.1 (MF59) and Uses a Surface Antigen From a Potential Pandemic Virus Strain Candidate (H5N1) in Adult and Elderly Subjects
The present study will evaluate the immunogenicity, safety and tolerability of two doses of monovalent inactivated influenza vaccine that is adjuvanted with MF59C.1 (MF59) and uses a surface antigen from a potential pandemic…
- Trial name
- NCT00841646
- Testing
- Monovalent inactivated influenza vaccine
- Where
- 2 sites in Hungary
- Volunteers
- 343 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Depression, Generalized Anxiety
The Impact of Information Sources on Mental Health During the COVID-19 Pandemic
Study description: The present study seeks to investigate the impact of various sources of information on psychopathology, and specifically health anxiety, depression, and general anxiety, during the COVID-19 pandemic.
- Conditions
- Depression, Generalized Anxiety, Health Anxiety
- Trial name
- NCT04442360
- Testing
- Prospective study with two measurement points investigating the impact of viral mitigation protocols on mental health
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Dementia, Cognitive Impairment
Disease Containment Measures Among Older Adults During the Covid-19 Pandemia
This study will examine which impact lockdown strategies intending to prevent the spread of COVID-19 had on people with cognitive impairment and dementia.
- Conditions
- Dementia, Cognitive Impairment, Depression, Anxiety, Loneliness
- Trial name
- Co-AiT (NCT04792086)
- Where
- Norway
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Norwegian Centre for Ageing and Health
Influenza A Subtype H7N7 Infection
Evaluating the Safety and Immune Response of an H7N7 Vaccine in Healthy Adults
H7N7 is one type of influenza virus that may pose a threat to humans if an outbreak occurs. This study will evaluate the safety and immune response to an H7N7 vaccine in people who have previously received a live attenuated…
- Trial name
- NCT01534468
- Testing
- Monovalent Influenza Subvirion Vaccine, H7N7
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Covid-19, COVID-19 Related Psychosocial Burden
Psychosocial Care During the COVID-19 Pandemic in Acute Hospitals
Heads of all psychosomatic, psychiatric and psychological consultation and liaison (C\&L) services in acute care hospitals across all participating countries will be contacted and asked to participate in this international…
- Trial name
- NCT04753242
- Testing
- Online survey questionnaire
- Where
- 22 sites in Austria, Belgium and 14 more
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Pandemic Influenza
A Prospective Study to Examine the Effectiveness and Safety of Antivirals in Volunteers Who Receive Short-term Prophylaxis Against Pandemic Influenza
This aim of this project is to evaluate the efficacy of neuraminidase inhibitors as short-term prophylaxis against pandemic influenza infection in people who have close familial contact with the disease.
- Trial name
- PIPET C (NCT00640874)
- Where
- 8 sites in Australia
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kirby Institute
Coping Behavior, Mental Health Issue
The Changes of Coping With Stressful Events Among Adolescents Under the COVID-19 Pandemic.
This study aims to describe the changes in coping strategies used by adolescents for stressful life events under the background of epidemic normalization; and explore the causes of coping strategy changes of stressful life events…
- Trial name
- NCT05435469
- Testing
- Questionnaires
- Where
- China
- Volunteers
- 4,300 people, healthy volunteers welcome
- Sponsor
- Wei XIA, PhD
Influenza, Human
A Study to Find and Confirm the Dose and Assess Safety, Reactogenicity and Immune Response of a Vaccine Against Pandemic H5N1 Influenza Virus in Healthy Younger and Older Adults
The aim of this study is to evaluate the safety, reactogenicity and immunogenicity of the Flu Pandemic messenger RNA (mRNA) vaccine (including dose-finding and dose-confirmation) administered in healthy adults 18 to 85 years of…
- Trial name
- NCT06382311
- Testing
- Flu Pandemic mRNA_Dose level 1, Flu Pandemic mRNA_Dose level 2, Flu Pandemic mRNA_ Dose level 3.
- Where
- 21 sites in United States
- Volunteers
- 991 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Pandemic Influenza, Influenza A Virus Infection
Safety and Immunogenicity of H5N1 Adjuvanted, Inactivated, Split-Virion Pandemic Influenza Vaccine in Healthy Adults
The purpose of this study is to test different adjuvanted vaccine formulations as a two-dose schedule in immunologically naïve adults against one vaccine formulation without adjuvant in terms of tolerance and immunogenicity…
- Conditions
- Pandemic Influenza, Influenza A Virus Infection, Orthomyxoviridae Infections
- Trial name
- NCT00457509
- Testing
- A/H5N1 inactivated, split-virion influenza vaccine+Adjuvant, A/H5N1 inactivated, split-virion influenza vaccine
- Where
- 3 sites in Belgium
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Termination of Pregnancy, Covid19
Impact of COVID-19 Pandemic on Early Spontaneous Abortions and Early Termination of Pregnancy
To see the impact the COVID-19 pandemic has had on early spontaneous abortions and early termination of pregnancy in the first trimester
- Conditions
- Termination of Pregnancy, Covid19, Pregnancy Loss
- Trial name
- NCT04910958
- Where
- Israel
- Volunteers
- 411 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
COVID-19, Well-Being, Psychological
Getting INFORMED and Living Well Among Asian Americans in California
The project is to facilitate pandemic recovery by promoting emotional wellness among Asian Californians. The intervention includes a 6-week program in which participants may choose to receive text only or text + Lay Health Worker…
- Trial name
- NCT05968300
- Testing
- INFORMED-Living Well, Text Messaging Only
- Where
- 4 sites in United States
- Volunteers
- 616 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Psychological Factors
The Effect of Classical Music on Dental Students' Stress and Anxiety During the COVID-19 Pandemic
The students adapted to the environment for the first 2 days, were informed about the study, and their informed consent was obtained. Participants were asked to answer all questions and to give a single answer to each question.
- Trial name
- NCT06787833
- Testing
- Questionnaire, listening to music
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Aging
Improving Physical Activity and Mobility Via Live Online Exercise Sessions for Older Adults
The COVID-19 pandemic has undoubtedly resulted in an increased level of personal anxiety, reduced access to support services, and as a secondary complication, increased physical inactivity.
- Trial name
- NCT04627493
- Testing
- Online exercise
- Where
- Canada
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- McMaster University
Depression, Anxiety
Predictors and Mechanisms of Depression and Anxiety During the COVID-19 Pandemic
Study description: The present study seeks to investigate the predictors and maintaining mechanisms of depression and anxiety symptoms during the COVID-19 pandemic, exactly 3 months following the strictest viral mitigation…
- Trial name
- NCT04442204
- Testing
- Prospective study across two time-points examining the impact of viral mitigation protocols on mental health
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Influenza
Safety and Immunogenicity Study of GSK Biologicals' Pandemic Influenza Candidate Vaccine (H1N1) (GSK2340272A)
This trial is designed to assess the safety and immunogenicity of a prime-boost schedule of GSK Biologicals' investigational vaccine GSK2340272A in children aged between 3 and 17 years.
- Trial name
- NCT00964158
- Testing
- Pandemic influenza vaccine GSK2340272A
- Where
- 5 sites in Spain
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Covid19
COVID-19: The Effectiveness of Free Face Mask Distribution
The investigators will carry out a randomised trial of free face mask distribution in Stovner District, Oslo, Norway. Ten grocery stores will serve as study sites.
- Trial name
- NCT04866589
- Testing
- Distribution of free face masks
- Where
- Norway
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Norwegian Institute of Public Health
Covid19
Process Evaluation of a Residence-Based SARS-CoV-2 Testing Participation Pilot
Mixed-methods process evaluation of a residence-based asymptomatic SARS-CoV-2 testing participation pilot
- Trial name
- RB-TPP (NCT05045989)
- Testing
- Residence-based testing participation pilot (SARS-CoV-2 testing with relaxed social distancing restrictions)
- Where
- United Kingdom
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of Nottingham