Clinical trials: Panic Disorders
Panic Disorder
IL-33, sST2, and CRP in Panic Disorder
Panic disorder (PD) is characterized by recurrent and unexpected panic attacks and is associated with significant functional impairment. Increasing evidence suggests involvement of immune-inflammatory mechanisms in PD.
- Trial name
- NCT07444879
- Where
- Turkey (Türkiye)
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Elazığ Mental Health and Diseases Hospital
Panic Disorder, Agoraphobia
A Clinical Trial to Evaluate the Efficacy and Safety of Meltz, a Digital Therapeutic Device, for Improving Panic Symptoms in Patients With Panic Disorder
i. This randomized clinical trial will evaluate the efficacy and safety of Meltz, a digital therapeutic device that provides cognitive behavioral therapy (CBT) for adults with panic disorder. ii.
- Trial name
- Meltz (NCT07892885)
- Testing
- Meltz
- Volunteers
- 120 people
- Sponsor
- AIMNEXT
Depression Moderate, Anxiety, Social
Effects and Cost-effectiveness of e-Meistring - a Guided Internet-delivered Psychological Treatment
The goal of this observational multicentre study is to address the effectiveness and cost-effectiveness of providing a therapist guided internet based cognitive behavioural therapy (ICBT) for common mental disorders in a routine…
- Conditions
- Depression Moderate, Anxiety, Social, Panic Disorder
- Trial name
- NCT05868135
- Testing
- eMeistring
- Where
- 4 sites in Norway
- Volunteers
- 800 people
- Sponsor
- St. Olavs Hospital
Depression / Major Depressive Disorder, Anxiety Disorder (Panic Disorder or GAD)
Feasibility and Preliminary Outcomes of Compassion-Focused Group Therapy for Depression and Anxiety
This pilot study evaluated the feasibility and preliminary outcomes of compassion-focused group therapy (CFT) for adults with depression and/or anxiety who continued to experience symptoms despite previous treatment.
- Trial name
- NCT07876453
- Testing
- Compassion-Focused Group Therapy (CFT)
- Where
- Sweden
- Volunteers
- 21 people
- Sponsor
- Karolinska Institutet
Panic Disorder
Exosomal microRNAs as a Biomarker in Panic Disorder and in Response to CBT
Cognitive behavior therapy (CBT) has long been known as an effective treatment for anxiety disorders, either when given by a therapist or when self-administered through a computer program.
- Trial name
- NCT04029740
- Testing
- CBT- both internet and face to face, No intervention
- Where
- Israel
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Hebrew University of Jerusalem
Dexmedetomidine, Panic Attacks
Dexmedetomidine Nasal Spray for the Treatment of Panic Attacks in Adults
Panic attacks affect 13.2% of adults globally, with acute treatments (e.g., benzodiazepines) carrying dependency risks. Dexmedetomidine, an α₂-adrenergic agonist, achieves peak plasma levels in 5-15 min via nasal delivery and may…
- Trial name
- NCT07162649
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Tongji University
Panic Disorder
Psychoeducation Based on Acceptance and Commitment Therapy
The aim of this study is to manage individual psychoeducation in acceptance and commitment therapy for problems with panic disorder and to evaluate the effect of this program on rumination and self-resilience.
- Trial name
- NCT06704399
- Testing
- Acceptance and Commitment Therapy-Based Psychoeducation, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Muğla Sıtkı Koçman University
Bipolar Disorder
Evaluation of the Genetics of Bipolar Disorder
This study looks to identify genes that may affect a person's chances of developing bipolar disorder (BP) and related conditions.
- Trial name
- NCT00001174
- Where
- United States
- Volunteers
- 4,210 people
- Sponsor
- National Institute of Mental Health (NIMH)
Panic Disorder, Mental Illness
Efficacy and Safety of HB-1 for Panic Disorder
The purpose of this study is to determine the safety and efficacy of HB-1, versus placebo and two monotherapies, in male and female adult patients aged 18 to 65 years, inclusive, with Panic Disorder.
- Trial name
- NCT06483789
- Testing
- HB-1, Telmisartan Only Product in Oral Dose Form, Verapamil Only Product in Oral Dose Form
- Where
- 19 sites in Australia
- Volunteers
- 170 people
- Sponsor
- HB BioTech, LLC
Anxiety, Panic Disorder
The Use of a FDA Cleared, Drug-free, Breathing System for Anxiety and Panic Disorders in Children and Teens
This study will test the efficiency of the Freespira Breathing System in youth.
- Trial name
- NCT02998502
- Testing
- Freespira Breathing System
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Johns Hopkins University
Obsessive-Compulsive Disorder in Children, Anxiety Disorder of Childhood
Evaluation of Family-Based Behavioral Treatments for Youth With Anxiety and Obsessive-Compulsive Disorder
Anxiety and obsessive-compulsive disorders are among the most common in children. Although cognitive behavioral therapy (CBT) is an effective and evidence-based treatment for such disorders, access to CBT is often limited.
- Conditions
- Obsessive-Compulsive Disorder in Children, Anxiety Disorder of Childhood, Social Anxiety Disorder of Childhood, Obsessive-Compulsive Disorder in Adolescence
- Trial name
- NCT05967468
- Testing
- Family Based, Internet-Based Cognitive Behavioral Therapy, Bibliotherapy, low therapist contact SPACE, Relaxation and Mentorship
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Baylor College of Medicine
Panic Disorder, Panic Disorder (With or Without Agoraphobia)
Qigong and Multicomponent Exercise in Panic Disorder
Panic disorder is a psychiatric disease characterized by recurrent panic attacks that occur in expected or unexpected situations and create feelings of intense fear, restlessness and discomfort.
- Conditions
- Panic Disorder, Panic Disorder (With or Without Agoraphobia), Panic Attacks and Disorders, Qigong
- Trial name
- NCT07439224
- Testing
- Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Dokuz Eylul University
Anxiety, Anxiety Acute
Anxiety Skills Study
The purposes of this study are: (1) to identify baseline predictors of relative success in cognitive, behavioral, and mindfulness-based treatments for anxiety, (2) explore who benefits from a brief, video-based skill training…
- Conditions
- Anxiety, Anxiety Acute, Anxiety Chronic, Anxiety and Mood Disorders
- Trial name
- NCT07774481
- Testing
- Cognitive therapy, Behavioral therapy, Mindfulness-based therapy
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Ohio State University
Panic Disorder
Imagery Rescripting for Traumatic Panic Attack Memories
The current project consists of two studies investigating the phenomenological characteristics, centrality levels, and traumatic symptoms of panic attack memories, while testing the effectiveness of the Imagery Rescripting (ImRs)…
- Trial name
- NCT07769996
- Testing
- Imagery Rescripting
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- İmge eylem yılmaz namlı
Anxiety Disorders, Panic Disorder
Efficacy of Expectancy Focused Exposure Therapy for Anxiety Disorders
This clinical trial evaluates whether an optimized exposure-based treatment improves long-term outcomes for adults with anxiety disorders.
- Conditions
- Anxiety Disorders, Panic Disorder, Social Anxiety Disorder (SAD), Generalised Anxiety Disorder
- Trial name
- EFE-AD (NCT07753330)
- Testing
- Expectancy Focused Exposure, Anxiety Focused Exposure
- Where
- Chile
- Volunteers
- 203 people
- Sponsor
- University of Chile
Depression, Panic Disorder
Evaluating Clinical Routines for ICBT
The overall aim of this study is to test the clinical benefits of an AI-based decision support tool (DST) and to evaluate how the DST affects therapists and their patients with depression, social anxiety, or panic disorder during…
- Conditions
- Depression, Panic Disorder, Social Anxiety Disorder
- Trial name
- NCT05321628
- Testing
- Internet-based Cognitive Behavioural Therapy (iCBT) with Decision Support Tool, Internet-based Cognitive Behavioural Therapy (iCBT)
- Where
- Sweden
- Volunteers
- 401 people
- Sponsor
- Karolinska Institutet
Major Depression Moderate, Major Depression Severe
EEG Microstate Parameters and Neuroinflammatory Biomarkers in Patients With Treatment-Resistant Major Depressive Disorder Receiving ECT
This study aims to investigate the neurophysiological and inflammatory changes associated with electroconvulsive therapy (ECT) in patients diagnosed with Major Depressive Disorder who are resistant to at least two antidepressant…
- Conditions
- Major Depression Moderate, Major Depression Severe, Major Depression With Comorbid Anxiety Symptoms, Major Depression With Panic Attacks
- Trial name
- NCT07748091
- Testing
- Electroconvulsive Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Obsessive Compulsive Disorder (OCD), Pediatric Anxiety Disorders
Testing Delivery Modalities of Team-Based CBT for Pediatric Anxiety in Community Health Settings.
The purpose of this study is to test how the delivery of Cognitive Behavioral Therapy (CBT) for pediatric anxiety and OCD via different methods might increase its availability and effectiveness.
- Conditions
- Obsessive Compulsive Disorder (OCD), Pediatric Anxiety Disorders, Anxiety Disorder, Anxiety
- Trial name
- IMPACT-RI (NCT06934525)
- Testing
- Team-delivered, exposure-based CBT
- Where
- United States
- Volunteers
- 501 people
- Sponsor
- Bradley Hospital
Major Depression Moderate, Major Depression Severe
EEG Microstate and Neuroinflammatory Biomarkers in Older Age Patients With Major Depressive Disorder Receiving ECT
This study aims to investigate the neurophysiological and inflammatory changes associated with electroconvulsive therapy (ECT) in older age patients diagnosed with Major Depressive Episode, Major Depression, and Bipolar Disorder…
- Conditions
- Major Depression Moderate, Major Depression Severe, Major Depression With Comorbid Anxiety Symptoms, Major Depression With Panic Attacks
- Trial name
- NCT07740694
- Testing
- Electroconvulsive Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Obsessive Compulsive Disorder (OCD), Anxiety Disorder of Childhood or Adolescence
Comparative Effectiveness of Internet-based Versus Parent-Coached Cognitive-Behavioral Therapy For Children and Adolescents With Anxiety and OCD
Anxiety disorders in children and adolescents are common and confer significant disability. Cognitive behavioral therapy (CBT) is the recommended treatment for youth with anxiety, yet many families cannot access CBT due to cost…
- Conditions
- Obsessive Compulsive Disorder (OCD), Anxiety Disorder of Childhood or Adolescence, Social Anxiety Disorder of Childhood, Generalized Anxiety Disorder (GAD)
- Trial name
- ASTRO (NCT07024758)
- Testing
- Parent Coached Exposure Therapy, Family Based, Internet-Based Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 174 people
- Sponsor
- Baylor College of Medicine