Clinical trials: Panic Disorders
Depression, Dysthymic Disorder
RECOVERY: A Transdiagnostic Intervention for Anxiety and Depression
To investigate the efficacy and acceptability of a guided internet delivered transdiagnostic intervention, targeting mild to moderate clinical symptoms of anxiety and depression and emphasizing the changes taking place at the…
- Conditions
- Depression, Dysthymic Disorder, Panic Disorder, Social Phobia
- Trial name
- RECOVERY (NCT03917550)
- Testing
- Recovery (Transdiagnostic & self), Transdiagnostic
- Where
- Romania
- Volunteers
- 260 people
- Sponsor
- West University of Timisoara
Panic Disorder, Agoraphobia
Study of Virtual Reality Therapy and Cognitive Behavior Therapy in Panic Disorder With Agoraphobia
The study aims at comparing virtual reality therapy (VRT) with a usual cognitive behavior therapy (CBT) program for agoraphobia. A waiting list represents the control condition.
- Trial name
- NCT00129610
- Testing
- Virtual Reality Therapy, Cognitive Behavior Therapy
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Hospices Civils de Lyon
Depression, Unipolar, Anxiety Disorder Social
Trans-diagnostic Group CBT vs. Standard Group CBT for Depression, Social Anxiety and Agoraphobia/Panic Disorder
Transdiagnostic Cognitive Behavior Therapy (CBT) delivered in the individual format, have been proven just as effective as traditional diagnosis specific CBT manuals.
- Conditions
- Depression, Unipolar, Anxiety Disorder Social, Panic Disorder
- Trial name
- TRACT-RCT (NCT02954731)
- Testing
- UP-CBT, Standard-CBT
- Where
- 4 sites in Denmark
- Volunteers
- 292 people
- Sponsor
- Psychiatric Research Unit, Region Zealand, Denmark
Depression Moderate, Anxiety, Social
Effects and Cost-effectiveness of e-Meistring - a Guided Internet-delivered Psychological Treatment
The goal of this observational multicentre study is to address the effectiveness and cost-effectiveness of providing a therapist guided internet based cognitive behavioural therapy (ICBT) for common mental disorders in a routine…
- Conditions
- Depression Moderate, Anxiety, Social, Panic Disorder
- Trial name
- NCT05868135
- Testing
- eMeistring
- Where
- 4 sites in Norway
- Volunteers
- 800 people
- Sponsor
- St. Olavs Hospital
Panic Disorder, Panic Disorder (With or Without Agoraphobia)
Qigong and Multicomponent Exercise in Panic Disorder
Panic disorder is a psychiatric disease characterized by recurrent panic attacks that occur in expected or unexpected situations and create feelings of intense fear, restlessness and discomfort.
- Conditions
- Panic Disorder, Panic Disorder (With or Without Agoraphobia), Panic Attacks and Disorders, Qigong
- Trial name
- NCT07439224
- Testing
- Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Dokuz Eylul University
Treatment of Induced Panic Attack
Staccato Alprazolam in Panic Attack
We are developing Staccato™ Alprazolam for the treatment of Panic attacks associated with panic disorder. This study will provide an initial assessment of efficacy, and to continue to describe the tolerability and…
- Trial name
- NCT00477451
- Testing
- Inhaled alprazolam 1 mg, Inhaled alprazolam 2 mg, IV doxapram
- Where
- 3 sites in United States
- Volunteers
- 49 people
- Sponsor
- Alexza Pharmaceuticals, Inc.
Panic Disorder
Disruption of Memory Reconsolidating as a Treatment for Panic Disorder
Animal and human fear conditioning studies have repeatedly shown that administering propranolol before or after retrieval of a previously acquired fear results in an elimination of the fear expression.
- Trial name
- NCT02631694
- Testing
- Propranolol, Carbon dioxide, Compressed air
- Volunteers
- 60 people
- Sponsor
- VU University of Amsterdam
Generalized Anxiety Disorder, Panic Disorder
Aripiprazole for the Treatment of Refractory Anxiety
The purpose of this study is to determine whether aripiprazole is effective in the treatment of refractory panic and generalized anxiety disorder.
- Trial name
- NCT00438386
- Testing
- Aripiprazole
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Panic Disorder
Self-Guided CBT Mobile App for Treatment-Resistant Panic Disorder (CBT) Cognitive Behavioral Therapy
Treatment-resistant panic disorder (TRPD) is characterized by persistent panic symptoms despite adequate pharmacological and/or psychotherapeutic treatment.
- Trial name
- (CBT) (NCT07391943)
- Testing
- Experimental - Self-Guided CBT Mobile App
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Panic Disorder
Mobile-assisted Case Management for Panic Disorder
A panic attack (PA) is an intense form of anxiety accompanied by multiple somatic presentations, leading to frequent emergency department visits and impairing quality of life.
- Trial name
- MCM (NCT05832905)
- Testing
- Mobile and Wearable-assisted Case Management
- Where
- Taiwan
- Volunteers
- 159 people
- Sponsor
- En Chu Kong Hospital
Generalized Anxiety Disorder, Agoraphobia
Examining the Effects of Reduced Environmental Stimulation on Anxiety
The studies proposed in this protocol aim to explore the anxiolytic properties of floating as it relates to the central and autonomic nervous system.
- Conditions
- Generalized Anxiety Disorder, Agoraphobia, Panic Disorder, PostTraumatic Stress Disorder
- Trial name
- NCT03051074
- Testing
- Floating, Comparison
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Anxiety Disorder
Adjunctive Family CBT for Veterans With Anxiety
Despite the prevalence of posttraumatic stress disorder and anxiety disorders among Veterans, there has been limited focus on the development of interventions that include family members in treatments provided to Veterans.
- Trial name
- AF-CBT (NCT05340478)
- Testing
- Adjunctive Family - Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Anxiety, Panic Disorder
The Use of a FDA Cleared, Drug-free, Breathing System for Anxiety and Panic Disorders in Children and Teens
This study will test the efficiency of the Freespira Breathing System in youth.
- Trial name
- NCT02998502
- Testing
- Freespira Breathing System
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Johns Hopkins University
Panic Disorder
A Study to Evaluate Efficacy, Safety, and Tolerability of Darigabat in Participants With Panic Disorder
The purpose of this trial is to measure the efficacy, safety, and tolerability of darigabat (25 milligrams [mg] twice daily [BID]) compared with placebo in participants with panic disorder.
- Trial name
- NCT05941442
- Testing
- Darigabat
- Where
- 31 sites in United States
- Volunteers
- 80 people
- Sponsor
- AbbVie
Major Depression Moderate, Major Depression Severe
EEG Microstate and Neuroinflammatory Biomarkers in Older Age Patients With Major Depressive Disorder Receiving ECT
This study aims to investigate the neurophysiological and inflammatory changes associated with electroconvulsive therapy (ECT) in older age patients diagnosed with Major Depressive Episode, Major Depression, and Bipolar Disorder…
- Conditions
- Major Depression Moderate, Major Depression Severe, Major Depression With Comorbid Anxiety Symptoms, Major Depression With Panic Attacks
- Trial name
- NCT07740694
- Testing
- Electroconvulsive Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Major Depression With Panic Attacks, Panic Disorder
A Single-Blind Trial of Risperidone vs. Paroxetine for Treatment of Panic Attacks
This study compares the efficacy of risperidone to that of paroxetine in the treatment of panic attacks in patients with Panic Disorder and with Major Depressive Disorder with Panic attacks and compares the side effect profile of…
- Trial name
- NCT00457106
- Testing
- Paroxetine, Risperidone
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Beth Israel Medical Center
Panic Disorder With Agoraphobia, Panic Disorder Without Agoraphobia
A Transdiagnostic, Self-guided Internet Intervention ("Velibra") for Waitlist Patients With Anxiety Disorders
The project's aim is to investigate the effect of a transdiagnostic, self-guided, internet-based cognitive behavioral therapy program in waitlist patients with anxiety disorders.
- Conditions
- Panic Disorder With Agoraphobia, Panic Disorder Without Agoraphobia, Generalized Anxiety Disorder, Social Anxiety Disorder
- Trial name
- NCT04793828
- Testing
- Velibra
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Charite University, Berlin, Germany
Generalized Anxiety, Stress Disorder, Posttraumatic
CBT for Anxiety Sensitivity vs. Disorder-specific CBT: An RCT
Adults with high anxiety sensitivity (AS) and a mental health diagnosis of anxiety, depression, or posttraumatic stress will be recruited and will be randomly assigned to either transdiagnostic cognitive behavioural therapy (CBT)…
- Conditions
- Generalized Anxiety, Stress Disorder, Posttraumatic, Social Anxiety, Major Depression
- Trial name
- NCT03015285
- Testing
- Cognitive Behavioural Therapy
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Panic Disorder, Phobic Disorders
Threat-Avoidance Learning in Anxiety Patients
Anxiety disorders are characterized by exaggerated levels of fear that are not proportional to the actual level of threat. More specifically, anxiety patients have marked deficits in the downregulation of fear reactions during…
- Conditions
- Panic Disorder, Phobic Disorders, Stress Disorders, Traumatic
- Trial name
- AVOID (NCT02336802)
- Testing
- Avoidance experiment
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Anxiety Disorders, Trauma
Respiratory Training in the Treatment of Transdiagnostic Pathological Anxiety
Purpose of the Research: The primary aim of the proposed study is to conduct a randomized parallel-group 2-arm clinical trial investigating capnometry-guided respiratory intervention (CGRI) for pathological anxiety.
- Conditions
- Anxiety Disorders, Trauma, Generalized Anxiety Disorder, Panic Disorder
- Trial name
- NCT05427708
- Testing
- Capnometry-Guided Respiratory Intervention, Psycho-Education
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Texas at Austin