Clinical trials: Panic Disorders
Anxiety Disorders, Generalized Anxiety Disorder
Effect of Mindfulness Meditation on Physiological Response to Unpredictable Stimuli
This study will evaluate the effects of Mindfulness-Based Stress Reduction (MBSR) on physiological reactivity. This study will focus on individuals with anxiety who will participate in an 8-week MBSR class.
- Conditions
- Anxiety Disorders, Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder
- Trial name
- NCT03206437
- Testing
- Mindfulness-Based Stress Reduction, Waitlist
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Georgetown University
Panic Disorder, Agoraphobia
Clinical Trial of a Group Self-management Support Program for Anxiety Disorders
Background. Self-management support is a complementary approach to treatment that aims to educate participants on the nature of anxiety and to improve their strategies to manage symptoms and well-being, thus presenting the…
- Conditions
- Panic Disorder, Agoraphobia, Social Anxiety Disorder, Generalized Anxiety Disorder
- Trial name
- NCT05124639
- Testing
- Group self-management support program for anxiety disorders
- Where
- Canada
- Volunteers
- 414 people
- Sponsor
- Université de Sherbrooke
Anxiety Disorders, Specific Phobia
Analyzing the Benefits of Using SYMPTOMS-JIT for in Vivo Exposure in Anxiety Disorders
The aim of this study is to develop and test the efficacy of first-of-its-kind, fully instrumented sensor-based smartphone-guided in-vivo exposure therapy using a just-in-time intervention for anxiety disorder.
- Conditions
- Anxiety Disorders, Specific Phobia, Panic Disorder, Agoraphobia
- Trial name
- NCT06788119
- Testing
- Cognitive behavioral therapy with in vivo exposure, Cognitive behavorial therapy with in vivo exposure plus SYMPTOMS-JIT
- Where
- Spain
- Volunteers
- 158 people
- Sponsor
- Universitat Jaume I
Generalized Anxiety Disorder, Social Anxiety Disorder
Level of Physical Activity and Fear Learning
The proposed experimental study will be the first to investigate whether exercise vs. sitting enhances consolidation of extinction learning in adults with high AS and anxiety disorders, and the mechanistic pathways of expectancy…
- Conditions
- Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder
- Trial name
- NCT05203731
- Testing
- Exercise, Sitting
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- NYU Langone Health
Panic Disorder
A Study to Evaluate the Use of Extended Release Alprazolam in the Treatment of Adolescents With Panic Disorder
The purpose of this study is to evaluate the efficacy, safety, tolerability, and pharmacokinetics of alprazolam extended release (XR) for the treatment of adolescents with panic disorder
- Trial name
- NCT00635531
- Testing
- alprazolam XR
- Where
- 18 sites in United States
- Volunteers
- 16 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Depression, Dysthymic Disorder
RECOVERY: A Transdiagnostic Intervention for Anxiety and Depression
To investigate the efficacy and acceptability of a guided internet delivered transdiagnostic intervention, targeting mild to moderate clinical symptoms of anxiety and depression and emphasizing the changes taking place at the…
- Conditions
- Depression, Dysthymic Disorder, Panic Disorder, Social Phobia
- Trial name
- RECOVERY (NCT03917550)
- Testing
- Recovery (Transdiagnostic & self), Transdiagnostic
- Where
- Romania
- Volunteers
- 260 people
- Sponsor
- West University of Timisoara
Panic Disorder, Healthy
Evaluation of Substance P Neurotransmission in Panic Disorder by PET Imaging of NK1 Receptors With [18F]SPA-RQ
This study is designed to observe the effects of a panic attack in patients with panic disorders and to demonstrate the involvement of Substance P in panic disorder, and thereby, further our understanding of its role in this…
- Trial name
- NCT00088738
- Testing
- [18F] SPA-RQ
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Dexmedetomidine, Panic Attacks
Dexmedetomidine Nasal Spray for the Treatment of Panic Attacks in Adults
Panic attacks affect 13.2% of adults globally, with acute treatments (e.g., benzodiazepines) carrying dependency risks. Dexmedetomidine, an α₂-adrenergic agonist, achieves peak plasma levels in 5-15 min via nasal delivery and may…
- Trial name
- NCT07162649
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Tongji University
Anxiety, Anxiety Acute
Anxiety Skills Study
The purposes of this study are: (1) to identify baseline predictors of relative success in cognitive, behavioral, and mindfulness-based treatments for anxiety, (2) explore who benefits from a brief, video-based skill training…
- Conditions
- Anxiety, Anxiety Acute, Anxiety Chronic, Anxiety and Mood Disorders
- Trial name
- NCT07774481
- Testing
- Cognitive therapy, Behavioral therapy, Mindfulness-based therapy
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Ohio State University
Anorexia Nervosa, Major Depressive Disorder
Neural Basis of Meal Related Interoceptive Dysfunction in Anorexia Nervosa
This study aims to identify the brain regions responsible for encoding cardiorespiratory 'interoceptive' sensations and determine whether they are dysfunctional in individuals affected by eating disorders, anxiety, depression, or…
- Conditions
- Anorexia Nervosa, Major Depressive Disorder, Generalized Anxiety Disorder, Panic Disorder
- Trial name
- NCT02615119
- Testing
- Isoproterenol, Normal saline
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Panic Disorder
A Study to Assess the Long-term Use of Alprazolam Extended Release (XL) in the Treatment of Adolescents With Panic Disorder
The purpose of this study is to evaluate the long-term (6-month) efficacy, safety, and tolerability of alprazolam XR in adolescents with panic disorder.
- Trial name
- NCT00635076
- Testing
- alprazolam XR
- Where
- 3 sites in United States
- Volunteers
- 3 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Alcohol Abuse, Drug Abuse
Adventure: Teacher Delivered Personality-targeted Interventions for Substance Misuse
Several personality factors have been shown to be associated with risk for alcohol and substance misuse, and differentiate substance abusers based on clinical profile, treatment response and susceptibility to other forms of…
- Conditions
- Alcohol Abuse, Drug Abuse, Depression, Panic Disorder
- Trial name
- Adventure (NCT00776685)
- Testing
- Personality-targeted interventions
- Where
- United Kingdom
- Volunteers
- 3,190 people, healthy volunteers welcome
- Sponsor
- King's College London
Post-traumatic Stress Disorder, Generalized Anxiety Disorder
Primary Care Intervention Strategy for Anxiety Disorders
This study will compare the effectiveness of an intervention strategy for the treatment of people with post traumatic stress disorder, generalized anxiety disorder, panic disorder, and social anxiety disorder in the primary care…
- Conditions
- Post-traumatic Stress Disorder, Generalized Anxiety Disorder, Panic Disorder, Social Anxiety Disorder
- Trial name
- NCT00347269
- Testing
- Cognitive-behavioral therapy, Psychotropic medication optimization, Treatment as Usual
- Where
- 4 sites in United States
- Volunteers
- 1,004 people
- Sponsor
- University of Washington
Anxiety Disorders, Depression
Tailored Internet-administrated Treatment of Panic Symptoms - A Randomised Controlled Trial
The purpose of this study is to determine whether tailored internet-administrated CBT is a feasible approach in the treatment of panic symptoms and comorbid anxiety and depressive symptoms.
- Trial name
- NOVA III (NCT01296321)
- Testing
- Tailored Internet-administrated CBT-Treatment, Waitlist
- Volunteers
- 57 people
- Sponsor
- Linkoeping University
Noncardiac Chest Pain, Panic Attack
Validation of the Panic Screening Score in Patient With Unexplained Chest Pain
Panic-like anxiety ( panic attacks with or without panic disorder), a highly treatable condition, is the most prevalent condition associated with unexplained chest pain in the emergency department.
- Trial name
- NCT02405052
- Testing
- No intervention
- Where
- Canada
- Volunteers
- 3,000 people
- Sponsor
- CISSS de Chaudière-Appalaches
Panic Disorder
A Study Of Sertraline Compared With Paroxetine In The Treatment Of Panic Disorder
To evaluate the efficacy and safety of sertraline compared to paroxetine in patients with panic disorder.
- Trial name
- NCT00677352
- Testing
- sertraline, Paroxetine
- Where
- 22 sites in Japan
- Volunteers
- 321 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Asthma, Panic Disorder
LUCHAR - Latinos Using Counseling for Help With Asthma and Anxiety Reduction
The research plan involves two aims: 1) Cultural adaptation of the Panic-Asthma Treatment and 2) a randomized, placebo-controlled pilot study.
- Trial name
- LUCHAR (NCT01583296)
- Testing
- Music Relaxation Therapy (MRT), CBT and HRVB
- Where
- 2 sites in United States
- Volunteers
- 53 people
- Sponsor
- Albert Einstein College of Medicine
Atrial Fibrillation Paroxysmal, Panic
The Relationship Between Panic Attack Symptoms and Atrial Fibrillation Episodes.
To characterize the relationship between panic attack symptoms and atrial fibrillation episodes using a real-time assessment data capturing system that reduces recall biases of previous research.
- Conditions
- Atrial Fibrillation Paroxysmal, Panic, Panic Disorder, Panic Attacks
- Trial name
- NCT04634461
- Testing
- Cardiac Monitor
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- State University of New York at Buffalo
Posttraumatic Stress Disorder (PTSD), Generalized Anxiety Disorder (GAD)
Metacognitive Therapy vs Unified Protocol for Patients With Comorbid Anxiety Disorders
The primary goal of this randomized controlled trial is to compare the effectiveness of two transdiagnostic psychological treatments, Metacognitive Therapy (MCT) and the Unified Protocol for Transdiagnostic Treatment of Emotional…
- Conditions
- Posttraumatic Stress Disorder (PTSD), Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), Panic Disorder (With or Without Agoraphobia)
- Trial name
- NCT06971692
- Testing
- Metacognitive therapy (MCT), Unified protocol (UP)
- Where
- Sweden
- Volunteers
- 114 people
- Sponsor
- Karolinska Institutet
Panic Disorder
Guided and Traditional Cognitive Behavioral Therapy Protocol for Resistant Panic
Self-guided therapy for anxiety disorders has focused on various cognitive-behavioral treatments mediated by technologies such as web applications.
- Trial name
- NCT07247955
- Testing
- The group intervention used the sessions described in traditional form, The group intervention used the sessions described in a self-guided format using an application
- Where
- Brazil
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro