Clinical trials: Panic Disorders
Major Depressive Disorder, Persistent Depressive Disorder
Transdiagnostic Psychotherapy for Veterans With Mood and Anxiety Disorders
Cognitive behavioral therapy (CBT) is a brief, efficient, and effective psychotherapy for individuals with depressive and anxiety disorders.
- Conditions
- Major Depressive Disorder, Persistent Depressive Disorder, Posttraumatic Stress Disorder, Panic Disorder
- Trial name
- TBT-RCT (NCT01947647)
- Testing
- Transdiagnostic Behavior Therapy, Behavioral Activation Therapy
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- VA Office of Research and Development
Panic Disorder
CO2 Inhalation and Risk for Panic Disorder
Objective: To examine respiratory/physiological and subjective responding as well as genetic transmission among offspring of parents with a history of or current panic disorder (PD) diagnosis to determine whether…
- Trial name
- NCT00930657
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- National Institute of Mental Health (NIMH)
Generalized Anxiety Disorder, Social Phobia
Effectiveness of Six Sessions CBT for Adolescents With Emotional Problems in Community Clinics
Background: There is need for more effectiveness studies concerning treatment of emotional symptom problems indicating anxiety and depression in adolescents.
- Conditions
- Generalized Anxiety Disorder, Social Phobia, Agoraphobia, Depression
- Trial name
- SMART (NCT02150265)
- Testing
- SMART manual cognitive behavioral therapy
- Where
- Norway
- Volunteers
- 163 people
- Sponsor
- University of Tromso
Alcoholism, Generalized Anxiety Disorder
Levetiracetam for the Treatment of Alcohol Dependence and Anxiety
The purpose of this study is to determine if levetiracetam is effective in treating alcohol dependence in patients with anxiety symptoms.
- Conditions
- Alcoholism, Generalized Anxiety Disorder, Panic Disorder, Social Phobia
- Trial name
- NCT00141115
- Testing
- levetiracetam
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- New York State Psychiatric Institute
Depression, Dysthymic Disorder
RECOVERY: A Transdiagnostic Intervention for Anxiety and Depression
To investigate the efficacy and acceptability of a guided internet delivered transdiagnostic intervention, targeting mild to moderate clinical symptoms of anxiety and depression and emphasizing the changes taking place at the…
- Conditions
- Depression, Dysthymic Disorder, Panic Disorder, Social Phobia
- Trial name
- RECOVERY (NCT03917550)
- Testing
- Recovery (Transdiagnostic & self), Transdiagnostic
- Where
- Romania
- Volunteers
- 260 people
- Sponsor
- West University of Timisoara
Panic Disorder, Panic Disorder With Agoraphobia
Construction of a Questionnaire on Panic Disorder and Agoraphobia
For the first time panic disorder and agoraphobia are included as separate disorders in the DSM-5. Thus, agoraphobia no longer represents a subcategory of panic disorder.
- Conditions
- Panic Disorder, Panic Disorder With Agoraphobia, Agoraphobia, Agoraphobia With Panic Attacks
- Trial name
- NCT03885453
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- Ulrike Willutzki
Major Depressive Disorder, Social Anxiety Disorder
Transdiagnostic iCBT for Depression and Anxiety
This 8-week, pilot randomized, controlled trial to evaluate the benefits of transdiagnostic Internet-based CBT (iCBT) in young adults with MDD, SAD, PD or GAD.
- Conditions
- Major Depressive Disorder, Social Anxiety Disorder, Panic Disorder, Generalized Anxiety Disorder
- Trial name
- NCT02266693
- Testing
- iCBT
- Where
- Canada
- Volunteers
- 77 people
- Sponsor
- Centre for Addiction and Mental Health
Major Depressive Disorder, Obsessive-Compulsive Disorder
Bioequivalence Study of Paroxetine Tablets and Paxil® Under Fasting and Fed Conditions in Chinese Healthy Volunteers
The objective of this study is to compare the rate and extent of absorption of paroxetine hydrochloride 20 mg tablets (test) and Paxil® (reference) administered as 20 mg tablet under fed conditions.
- Conditions
- Major Depressive Disorder, Obsessive-Compulsive Disorder, Panic Disorder, Social Anxiety Disorder
- Trial name
- NCT03504475
- Testing
- Paroxetine Hydrochloride Tablet 20 mg, Paxil® 20 mg
- Where
- 2 sites in China
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Panic Disorder
Org 25935 Versus Placebo as Augmentation to Cognitive-behavioral Therapy to Treat Panic Disorder (P05705)
The purpose of this study is to evaluate the effectiveness of Org 25935 vs. placebo given in combination with cognitive-behavioral therapy (CBT) to reduce the symptoms of panic disorder.
- Trial name
- NCT00725725
- Testing
- Cognitive-behavioral therapy, Org 25935
- Volunteers
- 46 people
- Sponsor
- Merck Sharp & Dohme LLC
PTSD, Panic Attacks
Exposure Therapy For Veterans With PTSD And Panic Attacks
To evaluate the feasibility, acceptability and effectiveness of Multiple Channel Exposure Therapy-Veterans (MCET-V) as a treatment for returning service members with comorbid PTSD and panic disorder (PD).
- Trial name
- NCT01033136
- Testing
- Multiple Channel Exposure Therapy - Veterans, Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- VA Office of Research and Development
Panic Disorder, Agoraphobia
Virtual Reality Exposure Therapy in Agoraphobic Participants
Virtual Reality Exposure Therapy (VRET) is an effective treatment for anxiety disorders, particularly for specific phobias as fear of heights and fear of flying (e.g. Powers \& Emmelkamp, 2008).
- Trial name
- NCT00734370
- Testing
- Virtual Reality Exposure Therapy for agoraphobic participants, Standard exposure in vivo for agoraphobic participants
- Where
- Netherlands
- Volunteers
- 55 people
- Sponsor
- VU University of Amsterdam
Depression, Anxiety Disorders
Effectiveness & Cost-effectiveness of Internet-delivered Interventions for Depression and Anxiety Disorders in IAPT
Depression and anxiety are common mental health problems. There are effective treatments for depression and anxiety and one of these is talking therapies using cognitive behaviour therapy (CBT).
- Conditions
- Depression, Anxiety Disorders, Depressive Disorder, Generalized Anxiety Disorder
- Trial name
- D-IAPT (NCT03188575)
- Testing
- SilverCloud Internet-delivered Cognitive Behavioural Therapy, Waiting List
- Where
- United Kingdom
- Volunteers
- 384 people
- Sponsor
- Silver Cloud Health
Generalized Anxiety Disorder, Panic Disorder
Treatment of Late-life Anxiety in Primary Care Settings
The research study proposed is designed to examine the outcomes of a cognitive behavioral guided self-care intervention with older adults diagnosed with generalized anxiety disorder and recruited from a primary care setting.
- Conditions
- Generalized Anxiety Disorder, Panic Disorder, Anxiety Disorder Not Otherwise Specified
- Trial name
- NCT00938093
- Testing
- Cognitive behavioral therapy, Enhanced usual care
- Volunteers
- 60 people
- Sponsor
- Wake Forest University Health Sciences
Panic Disorder, Insomnia
Ramelteon for Sleep Initiation Insomnia in Individuals With Panic Disorder Who Are Also on Escitalopram for Anxiety
Almost 80% of panic disorder patients report difficulty sleeping. Sleep disturbances in turn may exacerbate underlying anxiety/panic attacks.
- Trial name
- NCT00746239
- Testing
- Ramelteon and Escitalopram
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Milton S. Hershey Medical Center
Panic Disorder
D-cycloserine Augmented CBT for Panic Disorder
The purpose of this study is to determine whether d-cycloserine augments the clinical effects of exposure-based cognitive-behaviour therapy for panic disorder.
- Trial name
- NCT01680107
- Testing
- d-cycloserine, cognitive-behaviour therapy
- Where
- United Kingdom
- Volunteers
- 33 people
- Sponsor
- University of Oxford
Depression, Dysthymic Disorder
Rumination Focus Cognitive Behavior Therapy
1. To investigate the efficacy and acceptability of a guided internet-delivered transdiagnostic intervention targeting repetitive negative thinking for individuals with elevated levels of depression and generalized anxiety…
- Conditions
- Depression, Dysthymic Disorder, Panic Disorder, Social Phobia
- Trial name
- iRFCBT (NCT03507114)
- Testing
- Rumination-Focused CBT (RFCBT)
- Where
- Romania
- Volunteers
- 90 people
- Sponsor
- West University of Timisoara
Post Traumatic Stress Disorder, Anxiety Disorders
Neuroimaging of Pavlovian Fear Conditioning Processes in Patients With Pathological Anxiety
The purpose of this study is to use functional magnetic resonance imaging to investigate how the human brain learns to form associations between neutral and emotional stimuli.
- Conditions
- Post Traumatic Stress Disorder, Anxiety Disorders, Panic Disorder, Social Phobia
- Trial name
- NCT03498599
- Testing
- Novelty facilitated extinction, Standard Extinction
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Texas at Austin
Phobia, Social, Panic Disorder
Sertraline in Generalized Social Phobia With Co-Occurring Anxiety and Mood Disorders
Selective serotonin reuptake inhibitors (SSRIs) including sertraline have been found to be effective in the treatment of generalized social phobia (GSP).
- Conditions
- Phobia, Social, Panic Disorder, Agoraphobia, Obsessive-Compulsive Disorder
- Trial name
- NCT00182533
- Testing
- Sertraline
- Where
- Canada
- Volunteers
- 170 people
- Sponsor
- Hamilton Health Sciences Corporation
Panic Disorder
Exposure, D-Cycloserine Enhancement, and Genetic Modulators in Panic Disorder
This is a 5-year double blind, randomized, controlled, trial conducted at three treatment sites, aimed at showing the acute and longer-term effects of DCS augmentation of exposure-based CBT for panic disorder relative to placebo…
- Trial name
- DCSPanic (NCT00790868)
- Testing
- d-cycloserine
- Where
- 4 sites in United States
- Volunteers
- 180 people
- Sponsor
- Boston University Charles River Campus
Panic Disorder
Genetic Causes of Panic Disorder
This study will try to identify genes that increase the risk of developing panic disorder-an anxiety disorder characterized by recurrent unexpected panic attacks-and that contribute to the abnormalities associated with it.
- Trial name
- NCT00083265
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- National Institute of Mental Health (NIMH)