Clinical trials: Paralysis
Spinal Cord Diseases, Spinal Cord Injuries
Optimization of Adaptive Rowing Seating
Adaptive sports programs are integral components to combating Veteran isolation, promoting wellbeing and seeking to build teams, networks, communities.
- Conditions
- Spinal Cord Diseases, Spinal Cord Injuries, Neurodegenerative Disorders, Cerebrovascular Accident With Associated Sequelae
- Trial name
- OARS (NCT07099625)
- Testing
- Adaptive Indoor Rowing Seat, Paddle Sport adaptive seating system
- Where
- 2 sites in United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Incomplete Spinal Cord Injury, Brown Sequard Syndrome
Walking Adaptability Post-Spinal Cord Injury
The purpose of this study is: (1) to establish assessment techniques (in our laboratory) to identify the functional integrity of long spinal tracts associated with adaptive walking recovery post-spinal cord injury and (2) to…
- Trial name
- NCT01851629
- Testing
- Locomotor Training, Cross-Sectional Testing (No Intervention)
- Where
- 4 sites in United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Florida
Spastic Diplegic Cerebral Palsy, Cerebral Palsy
Therapeutic Listening for Balance and Trunk Control in Children With Cerebral Palsy
This study evaluates whether adding Therapeutic Listening to a structured physiotherapy program can improve balance, trunk control, and reaction time in children with spastic diplegic cerebral palsy.
- Trial name
- TL-CSB-CP (NCT07808437)
- Testing
- Conventional Training, Therapeutic Listening
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- MTI University
Paraplegia, Spinal Cord Injuries
Natural History of Shoulder Pathology in Manual Wheelchair Users
Over 300,000 people in the United States have spinal cord injuries and many use manual wheelchairs for mobility. Most manual wheelchair users will develop shoulder injuries and pain that greatly affect quality of life and level…
- Conditions
- Paraplegia, Spinal Cord Injuries, Shoulder Pain, Tendinopathy
- Trial name
- NHSSI (NCT02600910)
- Where
- 2 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Stroke
Brain Stimulation-aided Stroke Rehabilitation: Neural Mechanisms of Recovery
The purpose of this study is to investigate whether benefits of training the affected hand in patients with stroke can be improved by combining training with a painless, noninvasive technique called Transcranial Direct Current…
- Trial name
- NCT01539096
- Testing
- tDCS: noninvasive brain stimulation, Constraint induced movement therapy (CIMT)
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Parkinsonian Syndrome, Parkinson Disease(PD)
A Study to Evaluate the Diagnostic Efficacy of DaTSCAN™ Ioflupane (123I) Injection in Single Photon Emission Computed Tomography (SPECT) for the Diagnosis of Parkinsonian Syndrome (PS) in Chinese Patients
This is a multicenter, open-label, non-controlled, non-randomized, phase 3 clinical study to compare the SPECT findings after a single IV administration of DaTSCAN™ ioflupane (123I) injection for patients with a clinical…
- Conditions
- Parkinsonian Syndrome, Parkinson Disease(PD), Multiple System Atrophy (MSA), Progressive Supranuclear Palsy (PSP)
- Trial name
- NCT04193527
- Testing
- DaTSCAN™ Ioflupane (123I) Injection
- Where
- 10 sites in China
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Cerebral Palsy
The Effect of Instrument Assisted Soft Tissue Mobilization and Stretching Exercises in Cerebral Palsy
The aim of the study; To investigate the effects of Instrument Assisted Soft Tissue Mobilizations and Stretching Exercises on flexibility, spasticity, balance and functional mobility in patients with CP.
- Trial name
- IASTM (NCT05042570)
- Testing
- Instrument Assisted Soft Tissue Mobilization, Stretching Exercises, Control Group / NDT program
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Vocal Cord Paralysis, Phonasthenia
A Novel Approach for Thyroplasty Type 1, With Prolene Mesh. A Prospective Study.
Larynx performs important functions of the aero-digestive tract, it has vital role in control of breathing, phonation, deglutition and protection of lower respiratory tract from aspiration.
- Conditions
- Vocal Cord Paralysis, Phonasthenia, Presbylarynges, Idiopathic Vocal Cord Paralysis
- Trial name
- NCT04458818
- Testing
- Prolene Mesh Vocal Cord Medialization Implant
- Where
- Pakistan
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Muhammad Rashid
Cerebral Palsy
Effectiveness of Routine Physical Therapy With Intensive Bimanual Training in Cerebral Palsy Children
Effectiveness of Routine Physical Therapy With or Without Home Based Intensive Bimanual Training on Clinical Outcomes in Cerebral Palsy Children
- Trial name
- NCT04755556
- Testing
- home based intensive bimanual training, Routine Physical Therapy
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Lahore
Mastication Disorder
The Reliability and Validity of Family Report Chewing Evaluation
The family has a primary prescription in the identification of the chewing disorder in children to plan appropriate rehabilitation program and implementation of the training.
- Trial name
- NCT03116646
- Testing
- Chewing evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Paraplegia, Endurance
Upper Limb Function in Paraplegic Individuals: Exploring Endurance, Performance, and Symptoms
Spinal cord injury (SCI) is a serious condition that causes physical, psychological, and social functional impairments. Paraplegia is characterized by the loss of motor and/or sensory function at the thoracic, lumbar, or sacral…
- Conditions
- Paraplegia, Endurance, Symptoms
- Trial name
- NCT07154472
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Neonatal Brachial Plexus Palsy
Forced Lefthandedness in Neonatal Brachial Plexus Palsy (NBPP) Children
The aim of the project is to assess the neurophysiological and functional consequences of forced lefthandedness in a population with right neonatal brachial plexus palsy (NBPP).
- Trial name
- NBPP (NCT04376372)
- Testing
- Functional testing, Magnetic resonance imaging, Electromyography
- Where
- Belgium
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Cerebral Palsy
Effect of Ergonomic Classroom Furniture on the Printing Legibility of Elementary Students With Cerebral Palsy
The purpose of this pilot study is to gather the data needed to do a larger research study to determine whether children with cerebral palsy print better sitting at an ergonomically-designed, custom-fitted school desk or at an…
- Trial name
- NCT00465686
- Testing
- ergonomic chair and desk (Q-Learn Classic Chair and Q-Learn Desk), ergonomic desk and chair (Q-Learn Desk)
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Cerebral Palsy
Evaluation the Feasibility and Effects of Kinect-based Computer Games as UE Training Tool in Cerebral Palsy Children
The purpose of this study is to design and evaluation the feasibility, effects of Kinect-based Computer Games as Upper Extremity Training Tool in Children with Cerebral Palsy.
- Trial name
- NCT02364245
- Testing
- Kinect, Traditional OT(30 Mins), Traditional OT(60 Mins)
- Where
- Taiwan
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Hemiplegia
Induced Motion Illusions Through Vision and Tendon Vibrations: Study of Interactions in Hemiplegic Subjects
Two movement illusion techniques can currently be used in clinical practice for motor rehabilitation after stroke hemiplegia: visual illusion (mirror therapy) and proprioceptive illusion (tendon vibration).
- Trial name
- OPTIVIBE (NCT04449328)
- Testing
- Computerized Mirror Therapy (CMT), Tendon vibration
- Where
- France
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Brachial Plexus Palsy, Image, Body
Imagery Ability in Obstetric Brachial Plexus Palsy
Obstetric brachial plexus palsy (OBPP) is the paralysis of the ipsilateral upper extremity after a brachial plexus injury that occurs during labor.
- Trial name
- NCT04193072
- Testing
- Assessment of imagery ability
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Cerebral Palsy, Bilateral Cerebral Palsy
Effects of HABIT-ILE in Adults with Bilateral Cerebral Palsy
This randomized controlled trial (RCT) aims to evaluate the effects of intensive Hand and Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE) in improving body structure, function, daily activities, and…
- Trial name
- NCT06767930
- Testing
- Hand and Arm Bimanual Intensive Therapy Including Lower Extremities, Conventional intervention
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Cerebral Palsy
Telehealth Virtual Reality Gaming on Cardiometabolic Health Among Youth With Cerebral Palsy
The primary purpose of this study is to examine the preliminary efficacy of 12-weeks of home-based exercise using consumer available virtual reality gaming technology, compared with a 12 week wait-list control group.
- Trial name
- NCT05336227
- Testing
- Virtual Reality Exergaming
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Cerebral Palsy, Brain Injury
Validation of a 3D Instrumented Serious Game to Evaluate Upper Limb Impairments in Children With Neuromotor Disorders
The goal of this clinical trial is to validate an instrumented 3D serious game to assess upper limb impairments in children with neuromotor disorders.
- Conditions
- Cerebral Palsy, Brain Injury, Neurological; Disorder, Nervous System
- Trial name
- Play2BEAPI (NCT06774456)
- Testing
- instrumented 3D serious game (BE API 3.0)
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Exercise, Children
Long-term Exercise Effects from Robotic Walking
The vision of the Long-term Exercise Effects from Robotic Walking (LEER) research program is to develop optimal, individualized exercise strategies that would in turn enhance the health and well-being of non-ambulatory children…
- Conditions
- Exercise, Children, Cerebral Palsy
- Trial name
- LEER (NCT04307602)
- Testing
- Exercise - High Intensity Interval Training (HIIT), Exercise - Submaximal Steady State Training (SST)
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lund University