Clinical trials: Parathyroid
Overweight and Obesity, Vitamin D Deficiency
Magnesium and Vitamin D Supplementation and Cardiometabolic Outcomes
The purpose of this study is to investigate the effects of a combined vitamin D and magnesium supplementation on parathyroid hormone and cardiometabolic health in persons living with obesity.
- Conditions
- Overweight and Obesity, Vitamin D Deficiency, Magnesium Deficiency, Cardiovascular Risk Factor
- Trial name
- NCT03134417
- Testing
- Vitamin D and magnesium, Vitamin D
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Drexel University
DiGeorge Syndrome, Velocardiofacial Syndrome
Velocardiofacial (VCFS; 22q11.2; DiGeorge) Syndrome Study
Velocardiofacial syndrome, also known as 22q11.2 syndrome or DiGeorge syndrome, has been associated with many features such as a cleft palate, heart defects, and learning, speech and feeding problems.
- Conditions
- DiGeorge Syndrome, Velocardiofacial Syndrome, 22q11.2 Syndrome
- Trial name
- NCT00105274
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Pancreatic Cancer, Thymic Cancer
Genetic Evaluation of Families With Endocrine Cancers
This study is being conducted to identify altered genetic factors that may exist and influence endocrine cancers in unrelated MEN1 families with different cancers.
- Conditions
- Pancreatic Cancer, Thymic Cancer, Parathyroid Disease, MEN1 Syndrome
- Trial name
- MEN1 (NCT01794676)
- Testing
- Blood draw
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Jersey Shore University Medical Center
Hemodyalysis, Kidney Tansplant
Assessment of Mineral and Bone Disorders in Kidney Transplant Recipients
This study aims to integrate bone measurements (including bone turnover markers (BTM), bone mineral density (BMD) measurement, vertebral fracture assessment (VFA), trabecular bone score (TBS) ) commonly used in the general…
- Conditions
- Hemodyalysis, Kidney Tansplant, Osteoporosis, CKD-MBD - Chronic Kidney Disease Mineral and Bone Disorder
- Trial name
- NCT07141043
- Where
- Romania
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
Osteoporosis, Secondary Hyperparathyroidism
Calcium and Vitamin D Malnutrition in Elderly Women
This study is designed to test whether calcium supplementation alone or calcium plus vitamin D reduces the incidence of fractures, reduces high parathyroid secretory activity, and halts bone loss in a population-based sample of…
- Trial name
- NCT00352170
- Testing
- calcium supplementation, calcium and vitamin D3 supplementation
- Volunteers
- 1,180 people, healthy volunteers welcome
- Sponsor
- Creighton University
Menopause
Milk on Gut Microbiome and Bone Remodeling CTX in Postmenopausal Women
Milk consumption drives beneficial effect on Bone Mass Density and on Gut Microbiome. Altered Gut Microbiome is associated with postmenopausal status, reduced Bone Mass Density, abnormal serum levels of Bone Turnover Markers…
- Trial name
- Milk-CTX-GM (NCT06050018)
- Testing
- YesMilkdiet, NoMilkdiet
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
Healthy
Vitamin D Supplementation and PTH Response Among Malaysian Adults
This clinical trial was designed to determine the efficacy of vitamin D supplementation on plasma 25-hydroxyvitamin D [25(OH)D] and intact parathyroid hormone (PTH) concentrations of Malaysian female adults of child-bearing age…
- Trial name
- NCT05281107
- Testing
- 600 IU vitamin D + 500 mg calcium, 1200 IU vitamin D + 500 mg calcium, 4000 IU vitamin D + 500 mg calcium
- Where
- Malaysia
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- IMU University, Malaysia
Parathyroid Adenoma, Thyroid Adenoma
Evaluation of a New CZT System
The purpose of the study is to check if the new CZT system has an advantage in detection of small osseous processes, thyroid adenomas, parathyroid adenomas and detection of sentinel node, in comparison with the techniques in use.
- Trial name
- NCT01084356
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Autism Spectrum Disorders
Social Interactions: Ocular Explorations and Pupillometry in Autism
The primary objective of this work will first to characterize in typical childhood, visual exploratory behavior and pupillary response associated with salience of human social stimuli (faces and body movements), and then to…
- Trial name
- ISEOP (NCT01647295)
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Bone Diseases, Endocrine
Bone Metabolism and Parathyroid Hormone-related Protein (PTHrP) Lactation Study
The primary aim of the study is to measure bone formation in both lactating and non-lactating post-partum women and compare these to those in healthy non-pregnant controls.
- Trial name
- NCT00430417
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Chronic Hypoparathyroidism
Cardiovascular Effects of Parathyroid Hormone Analogues in Chronic Hypoparathyroidism
The goal of this study is to evaluate cardiovascular effects of long-acting parathyroid hormone (PTH) analogues in adults with chronic hypoparathyroidism.
- Trial name
- PaTH CV (NCT07707479)
- Testing
- Arterial stiffness in the aorta by measurement of pulse wave velocity, Central blood pressures and reflected waves in the aorta, Carotid and femoral intima-media thickness (IMT) and number of carotid or femoral plaques
- Where
- 2 sites in Greece
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Osteoporosis
Evaluation Of SB-751689 Administered At Supratherapeutic Dose Levels In Healthy Adult Subjects.
This study will evaluate the safety, tolerability and exposure of SB-751689 when administered alone at supratherapeutic doses and when SB-751689 is co administered with ketoconazole, a PGP/CYP3A4 inhibitor that increases exposure…
- Trial name
- NCT00468689
- Testing
- SB-751689 oral tablets (100 and 400 ng), Ketoconazole (NIZORAL) oral tablets (200 mg)
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Thyroid Cancer, Thyroid and Parathyroid Surgery
The Effect of Head Position on the Optik Nerve Sheath Diameter in Patients During Thyroid Surgery
THE EFFECT OF HEAD POSİTİON ON THE OPTİC NERVE SHEATH DİAMETER İN PATİENTS DURİNG THYROİD SURGERY
- Conditions
- Thyroid Cancer, Thyroid and Parathyroid Surgery, Thyroid Adenoma
- Trial name
- NCT07298187
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Voice Change, Hypocalcemia
The Use of Dexamethasone in Total Thyroidectomy to Improve Voice Outcome and Hypocalcaemia
Thyroidectomy is a standard procedure for benign and malignant pathologies of the thyroid gland. Each year, some 100 total thyroidectomies are performed in Kowloon East Cluster, Hospital Authority, Hong Kong.
- Trial name
- NCT05732883
- Testing
- Dexamethasone, Normal saline
- Where
- Hong Kong
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tseung Kwan O Hospital, Hong Kong
Hyperparathyroidism, Secondary
Impact of Parathyroidectomy on Vascular Calcification and Clinical Outcome in Hemodialysis Patients
The aim of this study is to assess the clinical, laboratory and vascular calcification outcome within 6 months duration in patients undergoing surgical parathyroidectomy (total, subtotal, and total with autotransplantation)
- Trial name
- NCT03724188
- Testing
- surgical parathyroidectomy
- Where
- Egypt
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Mansoura General Hospital
Osteoporosis
Nasally and sc Administered Teriparatide in Healthy Volunteers
Osteoporosis is a reduction in bone density that increases the risk of fractures; particularly of the spine, hip and wrist. Osteoporosis is estimated to affect 200 million women worldwide - approximately one tenth of women aged…
- Trial name
- NINTTO (NCT01913834)
- Testing
- Forsteo, CP046 PTH CriticalSorb
- Where
- United Kingdom
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Nottingham University Hospitals NHS Trust
Hyperparathyroidism
The Renin-Angiotensin-Aldosterone System and Parathyroid Hormone Control: The RAAS-PARC Study
This study will evaluate whether commonly used blood pressure medications called "ACE inhibitors" can lower parathyroid hormone.
- Trial name
- RAAS-PARC (NCT01691781)
- Testing
- Lisinopril
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Vitamin D Deficiency, Osteoporosis
Vitamin D Deficiency in Elderly African American Women in Central Texas
In order to make bone health a reality for older adults, we need to consider the prevalence of Vitamin D deficiency in relation to environment latitude as well as vitamin D supplementation.
- Conditions
- Vitamin D Deficiency, Osteoporosis, Osteopenia
- Trial name
- NCT01971411
- Testing
- Calcium 500mg with 200 IU Vitamin D - 2 tablets daily, Blood levels of Vitamin D, Serum CTX, Mg, Ca++ and iPTH, Usual sun exposure documentation
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- McLennan County Medical Education and Research Foundation
Primary Hyperparathyroidism, Bone Diseases, Metabolic
Radius Loading in Primary Hyperparathyroidism
The purpose of the study is to determine the effect of forearm exercise on forearm bone density in post-menopausal women with or without primary hyperparathyroidism.
- Conditions
- Primary Hyperparathyroidism, Bone Diseases, Metabolic, Osteoporosis, Postmenopausal, Bone Loss, Postmenopausal
- Trial name
- NCT01571843
- Testing
- Forearm exercise program, Walking program
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Columbia University
Chronic Hypoparathyroidism
AZP-3601 SAD and MAD Study in Healthy Subjects and Patients With Hypoparathyroidism
This study is investigating the safety, tolerability, pharmacodynamics and pharmacokinetics of AZP-3601 following single and repeated administration in both healthy volunteers and patients with chronic hypoparathyroidism (cHP)…
- Trial name
- NCT05239221
- Testing
- AZP-3601
- Where
- 2 sites in Hungary, Netherlands
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Alexion Pharmaceuticals, Inc.