Clinical trials: Parathyroid Adenoma
Breast Carcinoma, Prostate Cancer Surgery
High-resolution PET-CT Specimen Imaging for the Perioperative Visualization of Resection Margins
These are patients in whom a benign or malignant tumor was recorded requiring surgery. During that surgery, the surgeon will cut away the tumor as part of the treatment of the disease.
- Conditions
- Breast Carcinoma, Prostate Cancer Surgery, Thyroid Cancer, Parathyroid Adenomas
- Trial name
- NCT06835426
- Testing
- Single intravenous injection of the radiotracer, Imaging resected specimen using the high-resolution PET-CT specimen imager
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Parathyroid Adenoma, Parathyroid Neoplasms
Evaluating Impact of NIRAF Detection for Identifying Parathyroid Glands During Parathyroidectomy
This study describes a single center, randomized, single-blinded clinical trial to assess the clinical benefits of the use of near infrared autofluorescence (NIRAF) detection with an FDA-cleared device 'Parathyroid Eye (PTeye)'…
- Conditions
- Parathyroid Adenoma, Parathyroid Neoplasms, Parathyroid Hyperplasia, Parathyroid Cancer
- Trial name
- NIRAF (NCT04299425)
- Testing
- NIRAF Detection Technology
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Parathyroid Dysfunction, Adenoma
Does Fluorescence With or Without Indocyanine Green Improve Parathyroid Identification and Preservation
The aim of this study is to determine if fluorescence with or without indocyanine green can facilitate safe and accurate thyroid and parathyroid surgery.
- Trial name
- NCT06169735
- Testing
- Indocyanine green, SPY Portable Handheld Imaging
- Where
- United States
- Volunteers
- 417 people
- Sponsor
- University of Alabama at Birmingham
Parathyroid Gland Adenoma, Parathyroid Gland Atypical Adenoma
Molecular and Immunohistochemical Profiling of Tumors in Patients With Parathyroid Tumors
This trial studies molecular and immunohistochemical profiling of tumors in patients with parathyroid tumors. Studying molecular and immunohistochemical profiling of tumors may help doctors avoid inconsistencies in diagnosis…
- Conditions
- Parathyroid Gland Adenoma, Parathyroid Gland Atypical Adenoma, Parathyroid Gland Carcinoma, Primary Hyperparathyroidism
- Trial name
- NCT03039439
- Testing
- Biospecimen Collection, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 310 people
- Sponsor
- M.D. Anderson Cancer Center
Thyroid Cancer, Thyroid and Parathyroid Surgery
The Effect of Head Position on the Optik Nerve Sheath Diameter in Patients During Thyroid Surgery
THE EFFECT OF HEAD POSİTİON ON THE OPTİC NERVE SHEATH DİAMETER İN PATİENTS DURİNG THYROİD SURGERY
- Conditions
- Thyroid Cancer, Thyroid and Parathyroid Surgery, Thyroid Adenoma
- Trial name
- NCT07298187
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Parathyroid Diseases, Parathyroid Dysfunction
Near Infrared Autofluorescence (NIRAF) Detection for Identifying Parathyroid Glands During Parathyroidectomy
The goal of this study is to assess whether using PTeye (AiBiomed, Santa Barbara, CA) - a NIRAF detection modality - can improve patient outcomes and reduce healthcare associated costs after parathyroid surgeries.
- Conditions
- Parathyroid Diseases, Parathyroid Dysfunction, Parathyroid Neoplasms, Parathyroid Adenoma
- Trial name
- NCT05152927
- Testing
- Parathyroid Eye (PTeye)
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- University of California, San Francisco
Neuroendocrine Neoplasm, Neuroendocrine Neoplasm of Gastrointestinal Tract
Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients
Neuroendocrine neoplasms (NENs) are a heterogeneous group of lesions derived from cells with the ability to produce hormones that may arise from multiple different organs.
- Conditions
- Neuroendocrine Neoplasm, Neuroendocrine Neoplasm of Gastrointestinal Tract, Neuroendocrine Neoplasm of Lung, Thymic Neuroendocrine Neoplasm
- Trial name
- NCT06523582
- Where
- 3 sites in Mexico
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Mexico
Hyperparathyroidism, Primary
18F-Fluorocholine Positron Emission Tomography (PET) for the Detection of Parathyroid Adenomas
This is a prospective single arm single center Phase III study evaluating the ability of 18F-fluorocholine to detect the location of parathyroid adenomas.
- Trial name
- NCT04895631
- Testing
- 18F-Fluorocholine, Positron emission tomography (PET)
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- Thomas Hope
Primary Hyperparathyroidism Due to Adenoma
Near Infrared Autofluorescence Imaging in Minimally-Invasive Video-Assisted Parathyroidectomy (NIRAF MIVAP Study)
The role of near-infrared autofluorescence (NIRAF)-imaging as an adjunct in thyroid surgery is well established. However, its diagnostic role in hyperparathyroidism surgery is yet to be defined due to the lack of consensus…
- Trial name
- NIRAF MIVAP (NCT06779760)
- Testing
- parathyroidectomy
- Where
- Jordan
- Volunteers
- 24 people
- Sponsor
- Aristotle University Of Thessaloniki
Adenocarcinoma, Adenocystic Carcinoma
The Registry of Oncology Outcomes Associated With Testing and Treatment
This study is to collect and validate regulatory-grade real-world data (RWD) in oncology using the novel, Master Observational Trial construct. This data can be then used in real-world evidence (RWE) generation.
- Conditions
- Adenocarcinoma, Adenocystic Carcinoma, Anal Cancer, Appendix Cancer
- Trial name
- ROOT (NCT04028479)
- Testing
- Biomarker Testing (L), Systemic Treatment (T), Patient Reported Outcomes (P)
- Where
- 2 sites in United States
- Volunteers
- 167 people
- Sponsor
- Taproot Health
Parathyroid Adenomas, Hyperparathyroidism, Primary
Parathyroid Adenoma Detection With Rubidium-82 Imaging
Assess the uptake of rubidium-82 in parathyroid adenomas.
- Trial name
- PARAGON (NCT07099404)
- Testing
- PET/CT imaging with rubidium-82
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- Matthieu Pelletier-Galarneau, MD MSc
Primary Parathyroid Adenomas
Observation of Histological Changes in Parathyroid Adenomas Following High Intensity Focused Ultrasound (HIFU) Treatment Procedure
This study is a multicentre, open, uncontrolled trial for the observation of histological changes in parathyroid adenomas following high intensity focused ultrasound (HIFU).
- Trial name
- NCT01060982
- Testing
- Ultrasonic ablation device
- Where
- 2 sites in France
- Volunteers
- 5 people
- Sponsor
- Theraclion
Parathyroid Adenomas
Expanded Access:18F-Fluorocholine for the Detection of Parathyroid Adenomas
This expanded access protocol is proposed to allow University of California San Francisco (UCSF) patients additional access to 18F-fluorocholine (FCH) Positron Emission Tomography (PET) imaging for localization of parathyroid…
- Trial name
- NCT07218224
- Testing
- 18F-Fluorocholine (FCH), Positron emission tomography (PET)
- Sponsor
- Thomas Hope
Primary Hyperparathyroidism, Thyroid Disease
Optimization and Individualization of Diagnostic Scintigraphy Protocol and Minimally Invasive Radio-guided Parathyroid Surgery
The radio-guided technique offers both help with in-vivo identification and ex-vivo confirmation of parathyroid adenoma. In-vivo accuracy is most important but its results are not satisfactory.
- Conditions
- Primary Hyperparathyroidism, Thyroid Disease, Parathyroid Diseases, Parathyroid Adenoma
- Trial name
- NCT04344886
- Testing
- Conventional (dual-phase) SPECT/CT, Multi-phase SPECT/CT, Conventional minimally-invasive radio-guided parathyroidectomy
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- University Hospital Ostrava
Urachal Cancer, Parathyroid Carcinoma
Agnostic Therapy in Rare Solid Tumors
The ANTARES study is a phase II basket trial designed to evaluate the tissue-agnostic efficacy of the monoclonal anti-PD1 antibody, nivolumab, in patients with advanced or metastatic rare tumors.
- Conditions
- Urachal Cancer, Parathyroid Carcinoma, Fibrolamellar Carcinoma, Angiosarcoma
- Trial name
- ANTARES (NCT06638931)
- Testing
- Nivolumab
- Where
- 5 sites in Brazil
- Volunteers
- 28 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Parathyroid Gland Carcinoma, Parathyroid Gland Atypical Adenoma
Institution of an Italian Multicenter Database of Patients with Parathyroid Carcinoma or Atypical Parathyroid Adenoma
The goal of this observational study is to create, manage and analyze a multicenter national database of patients with parathyroid carcinoma or atypical parathyroid adenoma, aimed at collecting and studying anamnestic…
- Trial name
- NCT06645951
- Where
- 33 sites in Italy
- Volunteers
- 300 people
- Sponsor
- F.I.R.M.O. - Fondazione Italiana Ricerca sulle Malattie dell'Osso - Ente del Terzo Settore
Parathyroid Adenoma, Parathyroid Neoplasms
Evaluating Impact of Near Infrared Autofluorescence (NIRAF) Detection for Identifying Parathyroid Glands During Parathyroidectomy
This study will see if the use of near infrared autofluorescence (NIRAF) detection with an FDA-cleared device 'Parathyroid Eye (PTeye)' for identifying parathyroid glands (PGs) during parathyroidectomy (PTx) procedures is better…
- Conditions
- Parathyroid Adenoma, Parathyroid Neoplasms, Parathyroid Cancer, Hypercalcemia
- Trial name
- NCT05022641
- Testing
- PTeye, Standard of Care
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- University of Michigan
Parathyroid; Anomaly, Parathyroid Dysfunction
STP.168 Clinical Study Protocol Parakeet
STUDY PURPOSE The purpose of this study is to demonstrate the performance of the Parakeet Rapid Parathyroid Testing Kit by comparing Parakeet results with histopathologic Diagnosis.
- Conditions
- Parathyroid; Anomaly, Parathyroid Dysfunction, Hyperparathyroidism, Parathyroid Gland Adenoma
- Trial name
- Parakeet (NCT06499142)
- Testing
- Parakeet:The Parakeet Rapid Parathyroid Testing Kit is a rapid immunoassay designed to detect Parathormone (PTH) in a test sample.
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Neurovision Medical Products Inc
Parathyroid Disease
Anti-3-[18F]FACBC Imaging of Parathyroid Adenomas
Hyperparathyroidism (excessive production of parathyroid hormone (PTH) usually caused by a small growth called an adenoma in the parathyroid glands) is an increasingly significant medical and public health condition.
- Trial name
- NCT01574287
- Testing
- FACBC
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- David M. Schuster, MD
Parathyroid Gland Adenoma, Primary Hyperparathyroidism
Omission of Intact Parathyroid Hormone Testing During Surgery in Treating Patients With Primary Hyperparathyroidism
This clinical trial studies the omission of intact parathyroid hormone testing during surgery in treating patients with primary hyperparathyroidism.
- Trial name
- NCT03011736
- Testing
- Laboratory Biomarker Analysis, Parathyroidectomy
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Roswell Park Cancer Institute