Clinical trials: Paresthesia
Oral Submucous Fibrosis
Curcumin Plus Topical Steroid Versus Topical Steroid Alone for Oral Submucous Fibrosis
This study evaluates whether combining oral curcumin (a natural compound derived from turmeric) with a topical steroid is more effective than using a topical steroid alone in treating Oral Submucous Fibrosis (OSMF).
- Trial name
- NCT07891130
- Testing
- Curcumin and and triamcinolone acetonide, Triamcinolone Acetonide
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Liaquat College of Medicine and Dentistry
Chemotherapy-induced Peripheral Neuropathy, Chemotherapy-induced Neuropathic Pain
Analgesic Efficacy and Safety of Topical VMD-3866 Gel in Management of Pain Induced by Chemotherapy (CIPN)
Peripheral neuropathy is a disorder caused by damage to the peripheral nerves. Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of certain chemotherapy drugs, such as platinum-based compounds, taxanes…
- Conditions
- Chemotherapy-induced Peripheral Neuropathy, Chemotherapy-induced Neuropathic Pain, CIPN - Chemotherapy-Induced Peripheral Neuropathy, Peripheral Neuropathic Pain
- Trial name
- NCT07072468
- Testing
- VMD-3866 Gel
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- VM Therapeutics LLC
Carpal Tunnel Syndrome
Lipografting Versus Steroid Injections for Treatment of Carpal Tunnel Syndrome
This study applies the regenerative properties of autologous fat transfer to treat mild to moderate carpal tunnel syndrome in comparison to the current standard of care, corticosteroid treatment.
- Trial name
- NCT03722303
- Testing
- Fat Injection, Steroid Injection
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Columbia University
Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia
Gut Microbiome Profiles in Patients With Chemotherapy-induced Neuropathy in the RCT OzoParQT (NCT06706544).
Chemotherapy-induced peripheral neuropathy (CIPN) is a common and debilitating side effect of chemotherapy (CT), often requiring dose reductions or treatment interruptions, which can compromise efficacy of the planned CT…
- Conditions
- Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia, Numbness, Tingling
- Trial name
- OzoParQTmicrob (NCT06799351)
- Testing
- Ozone therapy
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Bernardino Clavo, MD, PhD
Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia
Ozone Treatment in Paresthesia (Numbness, Tingling) Secondary to Chemotherapy-induced Peripheral Neuropathy
The goal of this phase II/III randomized clinical trial is to evaluate the effect of adding rectal ozone therapy to the usual management of patients with paresthesia (numbness and/or tingling) due to chemotherapy-induced…
- Conditions
- Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia, Numbness, Tingling
- Trial name
- OzoParQT (NCT06706544)
- Testing
- Ozone therapy
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Bernardino Clavo, MD, PhD
Paresthesia, Total Hip Arthroplasty (THA)
Percussive vs. Gentle Massage for Recovery After Hip Replacement
Many people who have hip replacement surgery through a "bikini incision" on the front of the hip (anterior approach) develop numbness, tingling, burning, or tightness in the front and side of the thigh afterward.
- Conditions
- Paresthesia, Total Hip Arthroplasty (THA), Direct Anterior Total Hip Arthroplasty, Lateral Femoral Cutaneous Nerve Injury
- Trial name
- NCT07790705
- Testing
- Percussive Massage Therapy (Toloco or Hyperice Hypervolt GO 2), Gentle Manual Massage
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Zachary M Ricciardelli
Paresthesia and Hypoesthesia
Vitamin B Complex for Inferior Alveolar Nerve Paresthesia Recovery
Why is this study being done? Paresthesia is a change in sensation that can cause numbness, tingling, or loss of feeling in a part of the body.
- Trial name
- NCT07592897
- Testing
- Vitamin B Complex
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo
Atopic Dermatitis
Tolerance and Efficacy Open-label Study With RV4421B, in Various Populations With Atopic Dermatitis for 12 Weeks
Pierre Fabre Laboratories have developed a cream with medical device status, RV4421B-EV0407 indicated for the treatment of eczemas, including atopic eczema, contact eczema and chronic hand eczema.
- Trial name
- NCT07014007
- Testing
- RV4421B- EV0407
- Where
- Mauritius
- Volunteers
- 105 people
- Sponsor
- Pierre Fabre Dermo Cosmetique
Cervical Radiculopathy, Cervical Radicular Pain
Effects of Exercises and Electrical Current Application Aiming to Strengthen Neck and Shoulder Blades Muscles on Symptoms of a Pinched Nerve in the Neck
Cervical Radiculopathy (CR) is an objective loss of sensory and/or motor function as a result of compression or irritation of the cervical spinal nerve root.
- Conditions
- Cervical Radiculopathy, Cervical Radicular Pain, Neck Pain, Numbness
- Trial name
- NCT07375823
- Testing
- Exercise Therapy, Superimposition of electrical muscle stimulation on active movement
- Where
- Cyprus
- Volunteers
- 50 people
- Sponsor
- European University of Lefke
Inferior Alveolar Nerve Injury, Neurosensory Disturbance
Comparison of the Results of Biostimulation Treatment of Inferior Alveolar Nerve Injury Using Nd:YAG and Diode Lasers With Different Wavelengths.
Intraoral surgical procedures such as sagittal split osteotomy, dental implant placement, and surgical extraction of third molars are widely performed interventions in oral and maxillofacial surgery.
- Conditions
- Inferior Alveolar Nerve Injury, Neurosensory Disturbance, Paresthesia and Hypoesthesia, Nerve Regeneration
- Trial name
- NCT07416006
- Testing
- Nd:YAG Laser Biostimulation, Diode Laser Biostimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Skin Laceration, Skin Abrasion
Retrospective, Observationnal Study to Investigate Procedural Analgesia Delivered to Patients With Lacerations, Abrasions, Burns and Leg Ulcers.
The main part of the study is a retrospective analysis of 200 reports concerning patients with skin wounds and injuries : 50 consecutive patient reports dealing with skin lacerations 50 consecutive patient reports dealing with…
- Conditions
- Skin Laceration, Skin Abrasion, Skin Burn, Leg Ulcer
- Trial name
- APPABU (NCT07350811)
- Where
- France
- Volunteers
- 240 people
- Sponsor
- Versailles Hospital
Oral Submucous Fibrosis
Alternating Triamcinolone and Platelet-Rich Plasma Therapy for Oral Submucous Fibrosis
Oral Submucous Fibrosis (OSF) is a chronic, progressive, potentially malignant disorder characterized by mucosal stiffness, trismus, and burning sensation.
- Trial name
- RegenOSF (NCT07277998)
- Testing
- Platelet-Rich Plasma (PRP) Injections, Triamcinolone Acetonide
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Karachi Medical and Dental College
Interscalene Block, Postoperative Pain
Impact of Paresthesia on Postoperative Neurological Symptoms
In this study, the effect of paresthesia occurring during the interscalene block procedure on the incidence of postoperative neurological symptoms will be investigated.
- Trial name
- NCT06906458
- Testing
- Paresthesia, No paresthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara City Hospital Bilkent
Painful Diabetic Neuropathies
Safety and Efficacy Study for the Treatment of Painful Diabetic Neuropathy
The purpose of this study is to determine if Engensis (VM202) is safe and effective in treating painful diabetic neuropathy.
- Trial name
- NCT01475786
- Testing
- Low Dose: 16 mg Engensis (VM202), High Dose: 32 mg Engensis (VM202)
- Where
- 17 sites in United States, South Korea
- Volunteers
- 104 people
- Sponsor
- Helixmith Co., Ltd.
Meralgia Paresthetica, Chronic Low-back Pain (cLBP)
Dry Needling Versus Cyriax Technique on Pain, Paraesthesia and Functional Disability in Patients With Chronic Low Back Pain
This study is designed to compare the effectiveness of two physiotherapy techniques-Dry Needling and the Cyriax Technique-in people suffering from chronic low back pain (CLBP) that radiates to the outer thigh, a condition…
- Trial name
- NCT07089472
- Testing
- Dry Needling Therapy, Cyriax Technique
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- University of Lahore
Nitrous Oxide Abuse, Subacute Combined Cord Degeneration
Neurological Recovery Following NOS-SACD
Nitrous oxide has become an increasingly popular recreational drug amongst young people, particularly at festivals, nightclubs and parties.
- Conditions
- Nitrous Oxide Abuse, Subacute Combined Cord Degeneration, Neurologic Symptoms, Paresthesia
- Trial name
- NCT05714917
- Testing
- Observational study with no interventions
- Where
- 3 sites in United Kingdom
- Volunteers
- 100 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Muscle Weakness, Pain, Postoperative
Depo-Medrol on Psoas After LLIF
The goal of this study is to determine the effects of a corticosteroid administered to the psoas muscle following a transpsoas lateral lumbar interbody fusion (LLIF) on postoperative hip flexor weakness and thigh pain and…
- Conditions
- Muscle Weakness, Pain, Postoperative, Paresthesia, Pain, Muscle
- Trial name
- NCT05929755
- Testing
- Depo-Medrol, Gel-Flow NT
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Hardeep Singh
Surgical Complication, Paresthesia
Trial of Bilateral Sagittal Split Osteotomy Induced Paresthesia Using Ultrasonic vs. Reciprocating Saw Instrumentation
The aim of this prospective study is to analyze the postoperative paresthesias experienced in patients who undergo bilateral sagittal split osteotomies (BSSO) using an ultrasonic saw, versus a reciprocating saw.
- Conditions
- Surgical Complication, Paresthesia, Fracture, Nerve Injury
- Trial name
- NCT05205616
- Testing
- Sonopet ultrasonic saw, Reciprocating saw
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Carpal Tunnel Syndrome (CTS), Nerve Conduction
Comparative Analysis of Median Nerve Parameters for Carpal Tunnel Syndrome (CTS) Diagnosis: Ultrasound Versus Nerve Conduction Studies (NCS)
Comparative Analysis of Median Nerve Parameters for Carpal Tunnel Syndrome (CTS) Diagnosis: Ultrasound vs. Nerve Conduction Study (NCS) This clinical study aims to determine whether ultrasound can be as practical as NCS in…
- Conditions
- Carpal Tunnel Syndrome (CTS), Nerve Conduction, Ultrasound
- Trial name
- NCT06926777
- Testing
- Nerve Conduction Study
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Combined Military Hospital Kohat Pakistan
CIPN - Chemotherapy-Induced Peripheral Neuropathy
Internet-delivered Management of Chemotherapy-Induced Peripheral Neuropathy (CIPN)
This is a small pilot trial (n=26) among cancer survivors with CIPN who will utilize an internet-delivered pain coping program for 8 weeks in order to assess program feasibility and preliminary understanding of how participation…
- Trial name
- NCT05556447
- Testing
- Internet delivered pain coping skills training
- Sponsor
- Wake Forest University Health Sciences