Clinical trials: Parkinson Disease 10
Parkinson Disease (PD), Cognition
Short Term Effects of a Multimodal Intervention With RGM on Cognition in People With Parkinson's Disease.
The goal of this clinical trial is to learn if the Ronnie Gardiner Method (RGM) works to improve cognitive functions in adults with Parkinson's disease (early to mid-stage).
- Conditions
- Parkinson Disease (PD), Cognition, Quality of Life, Functional Mobility
- Trial name
- NCT07863219
- Testing
- Ronnie Gardiner Method
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- University Ghent
Parkinson Disease, Parkinson Disease 10
Video Dance Class and Unsupervised Physical Activity During Covid-19 Pandemic in People With Parkinson's Disease
The aim of this study is to analyze the impact of video dance class and unsupervised physical activity on clinical-functional parameters, self-isolation and non-motors symptoms in people with Parkinson's disease during the…
- Trial name
- PTT-Online (NCT04422353)
- Testing
- Video Dance classes, Unsupervised physical activities
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Federal University of Rio Grande do Sul
Parkinson's Disease
A Study of Istradefylline (KW-6002) in Treating Patients With Parkinson's Disease on Levodopa
To establish the efficacy of 10, 20 and 40 mg/d dose of istradefylline for reducing the percentage of OFF time in patients with advanced Parkinson's disease (PD) treated with levodopa.
- Trial name
- NCT00199420
- Testing
- Istradefylline (KW-6002)
- Where
- 2 sites in United States
- Volunteers
- 580 people
- Sponsor
- Kyowa Kirin, Inc.
Parkinson's Disease
Comparison of the Incidence of Dyskinesia in Parkinson's Disease Who Were Treated With Amantadine or Dopamine Agonist
The purpose of this study is to compare the onset time and severity of dyskinesia in amantadine or Dopamine agonist initial treated groups in Parkinson's disease.
- Trial name
- NCT01338662
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Seoul National University Hospital
Parkinson's Disease
Trial to Evaluate the Pharmacokinetics, Safety, and Tolerability of Rotigotine in Healthy Korean Subjects
The objective of this trial is to investigate the PK (Pharmacokinetic) of repeated-dose applications of the Rotigotine transdermal patch in healthy young male and female Korean subjects to be submitted to MFDS for new drug…
- Trial name
- NCT01964573
- Testing
- Rotigotine
- Where
- South Korea
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- UCB Pharma
Activity, Motor
Velocity-Loss Training and Parkinson's Disease
This study will compare the effects of velocity-loss resistance training at 10% and 30% velocity loss thresholds on measures of muscle strength and power and tests of daily performance in older adults with Parkinson's disease.
- Trial name
- NCT07840508
- Testing
- 10% Velocity-Loss Threshold Resistance Training, 30% Velocity-Loss Threshold Resistance Training
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Miami
Parkinson's Disease, Erectile Dysfunction
Sagene 2014 - Parkinson's Disease and Erectile Dysfunction
The purpose of this study is to see if selegiline and tadalafil (generic for Cialis®) results in an improvement in Erectile dysfunction (ED) in male patients with Parkinson's disease (PD) and moderate ED.
- Trial name
- NCT02225548
- Testing
- Selegiline, Tadalafil
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of South Florida
Excessive Daytime Sleepiness, Parkinson's Disease
Dose Range Finding Study of BF2.649 Versus Placebo to Treat Excessive Daytime Sleepiness in Parkinson's Disease Patients
The objective of this trial is to define the minimum effective dose of BF 2.649 between 5 mg, 10 mg, 20 mg or 40 mg versus placebo in reducing the Excessive Daytime Sleepiness of Parkinson's disease patients
- Trial name
- NCT00642928
- Testing
- BF 2.649 5 mg, BF 2.649 10 mg, BF 2.649 20 mg
- Where
- France
- Volunteers
- 108 people
- Sponsor
- Bioprojet
Parkinson's Disease
Deep Brain Stimulation Follow-up After 10 Years
The purpose of this study is to examine the long-term effect of Deep Brain Stimulation (DBS) for patients with Parkinson's Disease. We have data for patients operated with DBS since 1998.
- Trial name
- NCT01575132
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- University of Aarhus
Parkinson Disease 10
The Effects of Exercise in Parkinson's Disease
Parkinson's disease is caused by a reduction of dopamine causing motor deficits. The investigators are studying how exercise can help PD patients by increasing dopamine release in an area of the brain that coordinates movement…
- Trial name
- PET (NCT01835652)
- Testing
- Active Exercise, Passive Exercise
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- Pacific Parkinson's Research Centre
Parkinson Disease, Parkinson Disease 10
Effects of Nordic Walking in Parkinson Disease Patients
The aim of this study was to evaluate and compare the effects of a Nordic and free walking training program on clinical, functional and biomechanical parameters of gait, in people with PD.
- Trial name
- Walking (NCT03355521)
- Testing
- Nordic Walking, Free Walking
- Where
- Brazil
- Volunteers
- 33 people
- Sponsor
- Federal University of Rio Grande do Sul
Parkinson Disease, Parkinson's Disease
Phase 1 Clinical Trial to Evaluate the Safety, Efficacy, and Pharmacokinetics of IPS101A in Parkinson's Disease Patients
The purpose of this study is to evaluate the dose-related safety and tolerability of IPS101A, an adeno-associated virus (AAV) gene therapy, in patients with Parkinson's disease who exhibit severe functional impairment…
- Trial name
- NCT07371338
- Testing
- IPS101A
- Where
- South Korea
- Volunteers
- 6 people
- Sponsor
- Innopeutics Corporation
Parkinson Disease (PD)
Safety and Feasibility of Bilateral Striatal Transplantation of DopaCell in Parkinson's Disease
Dopason is a phase I, open-label, multicenter, single-arm clinical trial designed to evaluate the safety and feasibility of intraputaminal transplantation of human embryonic stem cell-derived dopaminergic progenitor cells…
- Trial name
- NCT07572071
- Testing
- Dopacell, Immunosuppressive Regimen, Customized microinjection device
- Where
- 3 sites in Iran
- Volunteers
- 6 people
- Sponsor
- Royan Institute
Triple Negative Breast Neoplasms
A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)
Researchers want to know if sacituzumab tirumotecan given alone or with pembrolizumab can treat triple negative breast cancer (TNBC).
- Trial name
- NCT06841354
- Testing
- Sacituzumab tirumotecan, Pembrolizumab, Rescue Medication
- Where
- 283 sites in United States, Argentina and 33 more
- Volunteers
- 1,000 people
- Sponsor
- Merck Sharp & Dohme LLC
Parkinson Disease, Parkinson Disease 10
Effects of Different Physical Therapies and Dance in People With Parkinson's Disease
The aim of study is to analyze the effects of different physical therapies (Aquatic Jogging, Neurofunctional Physiotherapy, Pilates Training and Nordic Walking) and Dance and compare with unsupervised home exercises in the…
- Trial name
- NCT03860649
- Testing
- Nordic Walking, Jogging, Dance
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Federal University of Rio Grande do Sul