Clinical trials: Parodontitis
Periodontitis
Comparison of Replantation and Splinting Alone in Lower Anterior Teeth
Replantation is defined as the intentional extraction and repositioning of teeth that have lost their periodontal support. The aim of this study is to evaluate the clinical and radiographic follow-up results of planned…
- Trial name
- NCT07141680
- Testing
- Replantation, Splint
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Saglik Bilimleri Universitesi
Apical Periodontitis
Comparison of AH Plus and WellRootST Root Canal Sealers in Terms of Postoperative Pain: One-Month Follow-up
This randomized, parallel-group clinical trial aimed to compare the effects of two root canal sealers, AH Plus and Well-Root ST, on postoperative pain in patients undergoing single-visit root canal treatment for teeth diagnosed…
- Trial name
- NCT07246174
- Testing
- AH Plus Root Canal Sealer, Well-Root ST Root Canal Sealer
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Medipol University
Chronic Periodontitis
Advantages of Autologous Platelet-Rich Fibrin Membrane on Growth Factor Levels and Periodontal Healing
Platelet rich fibrin is a second generation platelet concentration which contains various growth factors. The aim of this study is to evaluate the clinical and biochemical efficacy of PRF in subjects of chronic periodontitis in…
- Trial name
- NCT02898675
- Testing
- Platelet rich fibrine, Open Flap Debridement
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Healthy, Periodontitis
Effect of Non-Surgical Periodontal Treatment on Biomarker Levels
Periodontitis is a destructive disease that follows untreated gingivitis and is characterized by gingival inflammation, clinical attachment loss, alveolar bone loss and periodontal pocket formation, increased tooth mobility and…
- Trial name
- NCT06178081
- Testing
- Periodontal Healthy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Biruni University
Periodontal Diseases, Adverse Effects
Effect of Non-surgical Periodontal Treatment
Objective: The objective of this research was to compare the effect of a single session supragingival scaling in a group of pregnant women with periodontal disease with a group that received supra and subgingival scaling.
- Trial name
- EONSPT (NCT01533792)
- Testing
- Supra/subgingival scaling using periodontal curette scraping, Supra and subgingival scaling
- Volunteers
- 40 people
- Sponsor
- Universidade Federal do Maranhão
Apical Periodontitis, Chronic Kidney Diseases
Effects of RCT on Periapical Healing, Inflammatory Markers, and Kidney Function Indicators in CKD Patients With AP
The purpose of this prospective study is to determine the effect of non-surgical root canal treatment in chronic kidney disease patients and healthy patients with apical periodontitis.
- Trial name
- NCT06446011
- Testing
- root canal treatment in Ckd patients, root canal treatment in healthy patients
- Where
- India
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Chronic Kidney Disease Stage 5, Periodontitis
Effect of Non-surgical Periodontal Treatment and C-reactive Protein Levels in Hemodialysis Patients
The presence of periodontitis has been hypothesized as a risk factor for several systemic outcomes, including chronic kidney disease (CKD).
- Trial name
- NCT04262011
- Testing
- immediate treatment, postponed treatment
- Where
- Brazil
- Volunteers
- 88 people
- Sponsor
- Universidade Federal de Santa Maria
Peri-implant Mucositis, Peri-Implantitis
Chitosan Brushes vs Air-Abrasive Devices on Peri-implant Mucositis Treatment: A Randomized Clinical
Bleeding on probing (0,1,2,3), plaque index (+,-) and pocket probing depth will be recorded for each visit. Before the procedure, the patient will be randomly assigned to one of four groups and records will be kept.
- Conditions
- Peri-implant Mucositis, Peri-Implantitis, Bleeding on Probing, Periodontal Pocket
- Trial name
- NCT06287957
- Testing
- Labrida BioClean, EMS Handy 3.0 Perio Premium
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Chronic Periodontitis, Prehypertension
Impact of Periodontal Intervention on Vascular Dysfunction
The purpose of this study is to determine the effect of periodontal intervention on vascular dysfunction among Chinese prehypertensive adults with moderate to severe periodontal disease.
- Trial name
- NCT01917292
- Testing
- One-Stage Full-Mouth Disinfection, Periodontal care
- Where
- China
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Periodontal Diseases, Chronic Periodontitis
Effect of Switching From Cigarette Smoking to the Use of IQOS on Periodontitis Treatment Outcome
The purpose of this study was to demonstrate in patients with generalized chronic periodontitis that switching from cigarette smoking to using IQOS improves the response to periodontal therapy and the overall oral health status…
- Conditions
- Periodontal Diseases, Chronic Periodontitis, Periodontal Pocket, Tooth Mobility
- Trial name
- NCT03364751
- Testing
- IQOS, Cigarette
- Where
- 26 sites in Japan
- Volunteers
- 179 people
- Sponsor
- Philip Morris Products S.A.
Post Operative Pain
Assessment of Post-Operative Pain After Using Cryotherapy and Dexamethasone
Evaluation and comparing the effect of cryotherapy and dexamethasone on inflammatory mediators and post-operative pain in symptomatic irreversible pulpitis with acute apical periodontitis.
- Trial name
- NCT07738302
- Testing
- cold NaOCl , dexamethasone, NaOCl, dexamethasone, cold NaOCl and cold saline
- Volunteers
- 60 people
- Sponsor
- Suez Canal University
Periodontitis
Amoxicillin and Metronidazole During or After the Periodontal Treatment
This randomized clinical trial aimed to compare the clinical and microbiological effects of different times of administration of metronidazole (MTZ) and amoxicillin (AMX) in the treatment of periodontitis.
- Trial name
- NCT06177119
- Testing
- Scaling and root planing, Metronidazole during SRP, Amoxicillin during SRP
- Where
- Brazil
- Volunteers
- 72 people
- Sponsor
- Belén Retamal-Valdes
Atherosclerosis Cardiovascular Disease, Atherosclerosis of Artery
Oral Microbiome in Carotid Atherosclerosis
The goal of this observational study, called OMICA (Oral Microbiome in Carotid Atherosclerosis), is to learn how bacteria living in the mouth may influence the development and stability of plaques in the carotid arteries, which…
- Conditions
- Atherosclerosis Cardiovascular Disease, Atherosclerosis of Artery, Carotid Artery Plaque, Periodontitis
- Trial name
- OMICA (NCT07296965)
- Testing
- Sample Collection
- Where
- Hungary
- Volunteers
- 200 people
- Sponsor
- Semmelweis University Heart and Vascular Center
Chronic Periodontitis With Infra-bony Defects
Effect of Hyaluronic Acid in the Treatment of Periodontal Pockets
The aim of this study is to evaluate the effect of hyaluronic acid in the surgical treatment of periodontal pockets in people with gum disease. This research consists of clinical and radiographic studies.
- Trial name
- NCT02170857
- Testing
- Hyaluronic Acid
- Where
- Syria
- Volunteers
- 30 people
- Sponsor
- Damascus University
Periodontitis Chronic Generalized Moderate, Periodontitis Chronic Generalized Severe
Regular Home-use of Dual-light Photodynamic Therapy in the Management of Chronic Stage III-IV Periodontitis
This study is designed to determine the efficacy of the Lumoral method in chronic periodontitis with a targeted group of stage III and IV periodontitis.
- Trial name
- NCT05698823
- Testing
- Lumoral Treatment
- Where
- Lithuania
- Volunteers
- 56 people
- Sponsor
- Koite Health Oy
Marginal Bone Loss
Efficacy of Implant Surface Characteristics in Patients With History of Periodontitis
The aim of the study is to evaluate in patients with history of periodontitis the clinical, microbiological and radiological outcomes of implants with a modified implant design consisting on a machined surface in the coronal…
- Trial name
- NCT05010382
- Testing
- Implant placement surgery
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Complutense de Madrid
Chronic Periodontitis
Osteoprotegerin Before and After Periodontal Surgery
The study hypothesis: Is Osteoprotegerin a diagnostic and/or prognostic marker of periodontal disease?
- Trial name
- NCT02160613
- Testing
- Open flap debridement
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Chronic Apical Periodontitis
Adjunctive Oral Probiotics in Endodontic Retreatment: Effects on Postoperative Pain and RANKL/OPG Levels
This study aimed to evaluate the effect of oral administration of probiotics as an adjunctive treatment to local intracanal medicaments, namely propolis and calcium hydroxide or empty canal, on the levels of receptor activator of…
- Trial name
- RANKL/OPG (NCT07683520)
- Testing
- Linex Adult®, Ca(OH)2 as intracanal medicament, propolis intracanal medication
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Ain Shams University
Periodontitis
IL-6, IL-17 and IL-35 Levels in the Gingival Crevicular Fluid of Patients With Periodontitis and Healthy Controls
Periodontitis is an inflammatory disease characterized by periodontal tissue destruction caused by bacterial infection. The immune response plays an important role in the progression of periodontitis.
- Trial name
- NCT05306860
- Testing
- No intervention was applied to the groups the samples will be collected in terms of the diagnosis (periodontitis, healthy)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Apical Periodontitis
Apical Periodontitis and Glycemic Control in Diabetic and Non-diabetic Egyptian Sub-population
This observational cross-sectional study aims to assess the prevalence of apical periodontitis in diabetic and non-diabetic adult Egyptian patients and to evaluate its association with glycemic control measured by glycated…
- Trial name
- NCT07856186
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Cairo University
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