Clinical trials: Partial
Partial Edentulism
Comparison of Two Different Membranes
The purpose of the study is to compare one material called "Mucograft" with another material called "Dynamatrix." These materials are used as a type of a barrier (made from pig material also known as porcine material) in a…
- Trial name
- NCT01808794
- Testing
- Mucograft, Dynamatrix
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Tufts University
Dentin Bridge, Pulpitis
Partial Pulpotomy on Caries Free Human Teeth
The purpose of this study is to compare the human pulp response to partial pulpotomy using White ProRoot MTA or iRoot BP in the terms of dentinal bridge formation and inflammation.
- Trial name
- NCT01420718
- Testing
- MTA, iRoot BP
- Where
- Iran
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Healthy Adults
Enteral Nutrition and Immune Proteins Study
Eligible healthy adults who consent to take part in the study will be randomised to receive either a specialised milkshake for all of their normal daily diet (exculsive enteral nutrition, EEN) or the same specialised milkshake…
- Trial name
- ENIP (NCT06828094)
- Testing
- enteral nutrition
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Healthy
A Bio-equivalence Study of Sofosbuvir From Elbanovir 400 mg Film Coated Tablets ( Multi-Apex Pharma, Egypt) & Sovaldi 400 mg Film Coated Tablets (Gilead Sciences, United Kingdom)
Comparative randomized, single dose, three way three sequence two treatment partial replicate crossover open-label study to determine the bioequivalence of Sofosbuvir from Elbanovir 400 mg Film Coated Tablets ( Multi-Apex…
- Trial name
- NCT02605798
- Testing
- Elbanovir, Sovaldi
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Genuine Research Center, Egypt
Cancer
Study to Assess the Safety and Tolerability of MBF-118 in Healthy Volunteers
This is a single center, randomised, double blind, placebo controlled clinical study to assess the safety and tolerability of MBF-118 in healthy volunteers.This clinical phase I trial is divided in two stages and involves, first…
- Trial name
- NCT05921916
- Testing
- MBF-118 oral capsules
- Where
- Spain
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Medibiofarma S.L.
Missing Teeth
Single-retainer Lithium Di-silicate Versus Zirconia Resin Bonded Bridge for Replacement of an Anterior Missing Tooth.
First, Participants in this study will be recruit according to inclusion criteria. Proper examination for the participants (clinically and radiographically). Preparation for abutment tooth for Resin bonded fixed partial denture.
- Trial name
- RBFPD (NCT05861921)
- Testing
- Single-retainer Lithium Di-silicate Resin Bonded Fixed Partial Denture
- Where
- Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Cairo University
Ventilation, Bariatric Surgery
Effects of Different Anesthesia Machine Modalities on Bariatric Surgery Patients: a Prospective Randomized Controlled Study
The goal of this clinical trial is to explore the clinical significance and value of the PRVC ventilation mode in Bariatric Surgery Patients.
- Conditions
- Ventilation, Bariatric Surgery, Intracranial Pressure, Carbon Dioxide
- Trial name
- NCT06547411
- Testing
- PC Ventilation mode, VC Ventilation mode, PRVC Ventilation mode
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Yu-Long Jia
Crohn Disease
Fecal Microbiota Transplantation as the First-line Treatment in Active Pediatric Crohn's Disease
To explore the safety and effectiveness of repeated and multiple fecal microbiota transplantations (FMTs) plus partial enteral nutrition (PEN) as a first-line treatment for active Crohn's disease (CD) in children.
- Trial name
- FMT (NCT05321758)
- Testing
- Fecal Microbiota Transplantation, Immunosuppressive Agents
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Periodontal Disease, Caries
The Effects of Chlorhexidine/Thymol Varnish on Partial Denture Patient
Cervitec, a chlorhexidine based varnished has been proven to reduce caries risk in younger populations. This study wants to investigate if the use of this product would reduce the risk of losing abutment teeth on patients that…
- Trial name
- NCT02202304
- Testing
- Chlorhexidine/Thymol varnish
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rosa Moreno Lopez
Acute and Partial Sleep Deprivation
Cortical Excitability and Decision Making After Total Sleep Deprivation and Sleep Restriction
The investigators examine changes in decision making, vigilance and cortical excitability in healthy male subjects undergoing total acute sleep deprivation (40 hours) on the one hand, and chronic partial sleep restriction (7…
- Trial name
- NCT02305225
- Testing
- Sleep Deprivation
- Where
- Switzerland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Christian Baumann
Pain
Cebranopadol Effects on Ventilatory Drive, Central Nervous System (CNS) and Pain.
Opioids are potent painkillers but come with serious adverse effects ranging from addiction to potentially lethal respiratory depression via activation of μ-opioid receptors (MOP) at specific sites in the central nervous system.
- Trial name
- NCT05491785
- Testing
- Cebranopadol 600 µg, Cebranopadol 800 µg, Cebranopadol 1000 µg
- Where
- 2 sites in Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tris Pharma, Inc.
Epilepsy, Temporal Lobe, Cognitive Decline
Pre-operative Mapping of the Anterior Temporal Lobe Using Functional MRI Innovative Techniques in in Drug-resistant Epileptic Patients
Anterior temporal epilepsy is the most frequent form of focal epilepsy (more than 50% of focal epilepsies). The epilepsy is drug-resistant when epileptic seizures persist despite antiepileptic treatment (25% of cases).
- Trial name
- CARTA (NCT05339438)
- Testing
- functional MRI
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Molar Incisor Hypomineralization
Effectiveness of Pulpotomy in Carious First Permanent Molar
Pediatric dentists frequently encounter deeply carious young permanent first molars (PFM) with Molar Incisor Hypomineralisation (MIH).
- Trial name
- NCT06137391
- Testing
- Vital Pulp Therapy
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Healthy Volunteer
Calibration of a New Reflectance Oximeter.
This study is about the development of a new medical device for the monitoring of of sleep disordered breathing. This device is developed by the CEA-LETI-LE2S and will be composed of an oximeter, an actimeter in order to measure…
- Trial name
- PATCHSANTESpO2 (NCT02842255)
- Testing
- Calibrate the oximeter ALTITRAINER200®
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Caries, Dental
Management of Occlusal Dentinal Caries in Deciduous Molars
This study evaluated and compared the efficacy of no caries removal and sealing with a well-adapted and crimped stainless steel crown verses selective caries removal upto soft dentin and upto firm dentin in healing and/or…
- Trial name
- MOD (NCT03552835)
- Testing
- no caries removal, partial caries removal upto soft dentin, partial caries removal upto firm dentin
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sneha D. Suwarnkar
Localization-related Epilepsy, Partial Epilepsy
Improving Lesion Detection in Children With Magnetic Resonance Imaging (MRI)-Negative Partial Epilepsy Using Diffusion Tensor Imaging
Focal cortical dysplasia is one of the most common lesions responsible for medically refractory epilepsy in the pediatric population.
- Trial name
- NCT00894478
- Testing
- Diffusion Tensor Imaging (DTI), Magnetoencephalography
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Cardiovascular Disease
Clinical Trial to Evaluate the Safety and Pharmacokinetic Characteristics in Healthy Volunteers
This study is a randomized, open, single-dose, 3 period partial replicated crossover-design study to investigate the pharmacokinetic profiles and safety of CKD-333 in healthy volunteers.
- Trial name
- NCT04478097
- Testing
- CKD-330 Tab. and D086 Tab., CKD-333 Tab.
- Where
- South Korea
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Osteoporosis
A Study of TeriQ Patch in Healthy Adult Female Participants
This will be a single center, open-label, active-controlled, 3-way, incomplete block, crossover, randomized, and single escalating dose study.
- Trial name
- NCT06644040
- Testing
- TeriQ Patch, Teribone Inj., Forteo Inj.
- Where
- 2 sites in Australia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- QuadMedicine
Glaucoma, Open-Angle, Glaucoma Secondary
Assessment of Effectiveness Ex-Press Surgery Modification
The purpose of the study is to compare the effectiveness and safety profile of ExPress implantation versus partial deep sclerectomy combined with ExPress implantation with simultaneously phacoemulsification.
- Conditions
- Glaucoma, Open-Angle, Glaucoma Secondary, Glaucoma, Primary Open Angle
- Trial name
- NCT03800589
- Testing
- phacoemulsification with implantation of the Ex-Press, deep sclerectomy, phacoemulsification, ExPress implantation
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Military Institute od Medicine National Research Institute
Candida Albicans Infection
Evaluation of Candida Albicans Growth on BreFlex Versus PEEK Denture Base in Maxillary Bounded Partial Denture
This study evaluate Candida Albicans growth on Bre-Flex versus PEEK denture base in Bilateral Maxillary bounded partial denture , half of patients will receive a framework with breflex denture base and the other half will receive…
- Trial name
- NCT03462862
- Testing
- PEEK, Bre-Flex
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Cairo University