Clinical trials: Partial Nephrectomy, open to volunteers
Renal Cell Carcinoma (Kidney Cancer)
Virtual Renality: Assessing the Impact of Virtual Reality on Preoperative Planning in Renal Cancer Surgery
Rationale: Preoperative planning for both partial and radical nephrectomies using conventional CT imaging can be challenging due to complex renal anatomy and vascularization.
- Trial name
- NCT06960174
- Testing
- Virtual reality
- Volunteers
- 70 people
- Sponsor
- St. Antonius Hospital
Clear Cell Renal Cell Carcinoma
Neoadjuvant PD-L1 Inhibitor Plus Anlotinib for Kidney Preservation in Complex Renal Cell Carcinoma
This is a prospective, multicenter, single-arm phase II study evaluating the efficacy and safety of neoadjuvant PD-L1 inhibitor TQB2450 in combination with anlotinib in patients with locally advanced, high-complexity (RENAL score…
- Trial name
- NCT07602101
- Testing
- TQB2450 + Anlotinib
- Volunteers
- 33 people
- Sponsor
- RenJi Hospital
Kidney Cancer, Renal Neoplasms
Tumor Rupture During Robotic Partial Nephrectomy
The RUPTURE Project is a multi-center observational study aiming to understand tumor rupture during robotic partial nephrectomy (RAPN), a minimally invasive surgery used to treat kidney tumors.
- Trial name
- RUPTURE (NCT07065825)
- Testing
- robot-assisted partial nephrectomy
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Renal Cell Carcinoma (Kidney Cancer), Postoperative Pain
QLESP Block for Pain Control in Robotic Partial Nephrectomy
The goal of this clinical trial is to learn if an ultrasound-guided nerve block called QLESP works to reduce pain and the need for strong pain medicines after robotic kidney surgery in adults.
- Conditions
- Renal Cell Carcinoma (Kidney Cancer), Postoperative Pain, Nerve Block
- Trial name
- NCT07704970
- Testing
- ropivacaine (local infiltration), ropivacaine
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Huazhong University of Science and Technology
Tumoral Kidney
Rein 3D PRINT PERSONALIZE
The goal of this clinical trial is to compare preoperative information and patient experience using a personalized versus a generic 3D printed models of patients' tumoral kidney before and after nephron-sparing surgery.
- Trial name
- R3DP-P (NCT06379698)
- Testing
- personalized 3D model pré-opérative education, generic 3D model pré-opérative education
- Where
- France
- Volunteers
- 39 people
- Sponsor
- University Hospital, Bordeaux
Kidney Cancers
Photodynamic Diagnosis of Kidney Cancer Using Fluorescence Endoscopy and Oral 5-ALA
The goal of this prospective, single-arm feasibility study is to evaluate the safety and feasibility of using Gleolan® (5-aminolevulinic acid), an FDA-approved drug currently used during brain tumor surgery, in adults with…
- Trial name
- NCT07828704
- Testing
- 5-Aminolevulinic acid Hydrochloride (Gliolan®)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Henry Ford Health System
Prostate Cancer (Adenocarcinoma), Renal Cancer
Comparison Between HUGO RAS Robotic Platform and Da Vinci Robotic Platform
The study is designed as a single-center, prospective, interventional, non-pharmacological, randomized, open-label, controlled trial with parallel groups.
- Trial name
- URO-ROBOT-2023 (NCT06844513)
- Testing
- Radical prostatectomy, Partial nephrectomy
- Where
- Italy
- Volunteers
- 800 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Renal Neoplasms, Localized Kidney Tumors
Effect of Non-Clamping and Sutureless Technique on Postoperative Renal Function in Robot-Assisted Partial Nephrectomy
Partial nephrectomy is an operation that removes a kidney tumor while leaving the rest of the kidney in place. It is used to treat selected patients with small tumors confined to the kidney.
- Trial name
- NCT07888608
- Testing
- Off-Clamp, Sutureless Robot-Assisted Partial Nephrectomy, Conventional Robot-Assisted Partial Nephrectomy With Artery Clamping and Sutured Reconstruction
- Where
- China
- Volunteers
- 304 people
- Sponsor
- Shao Pengfei
Renal Cell Carcinoma (RCC)
Anlotinib + Benmelstobart vs Surgery for Patients With Localized Renal Cell Carcinoma Scheduled to Undergo Partial Nephrectomy
Evaluation of long-term renal function improvement, surgical safety, as well as efficacy and safety of preoperative anlotinib hydrochloride capsules combined with benmelstobart injection versus surgery in patients with localized…
- Trial name
- ALTER-UC-011 (NCT07627464)
- Testing
- Anlotinib hydrochloride + Benmelstobart + Partial nephrectomy, Partial nephrectomy
- Where
- 14 sites in China
- Volunteers
- 144 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Renal Tumor, Prone Position
Robot-assisted Laparoscopic Partial Nephrectomy Via the Extraperitoneal Approach in the Prone Position Versus the Lateral Position
The goal of this clinical trial is to investigate whether robot-assisted laparoscopic partial nephrectomy by extraperitoneal approach in the prone position had any advantages over the traditional lateral position.
- Conditions
- Renal Tumor, Prone Position, Robotic Assisted Partial Nephrectomy
- Trial name
- NCT06572501
- Testing
- Robot-assisted laparoscopic partial nephrectomy via extraperitoneal approach in the prone position, Robot-assisted laparoscopic partial nephrectomy via extraperitoneal approach in the lateral position
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Renal Tumors
A Multicenter Study of RUS NE
This sponsor-initiated, randomized controlled clinical trial aims to demonstrate the clinical efficacy of RUS NE Surgical Navigation System in patients undergoing robotic-assisted partial nephrectomy.
- Trial name
- NCT06868186
- Testing
- RUS NE
- Where
- 4 sites in South Korea
- Volunteers
- 204 people
- Sponsor
- Hutom Corp
Kidney Neoplasms
Cryaoablation Assisted Partial Nephrectomy a Non Ischemic Approach
Patients with renal masses eligible to partial nephrectomy often require arterial ischemia to control or prevent blood loss during this surgical procedure.
- Trial name
- RCAPN (NCT05218811)
- Testing
- Cryoablation Assisted Partial Nephrectomy
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Urological Research Network, LLC
Kidney Cancer, Kidney Neoplasms
Planning Operative Strategy Using a Digital Renal Artery Clamping Tool
A proposed new tool ('DIPLANN-tool' - Digital Planning in Nephrectomy) for predicting kidney perfusion zones on a segmented 3D model during robot-assisted partial nephrectomy (RAPN) for localized renal cancer demonstrated high…
- Conditions
- Kidney Cancer, Kidney Neoplasms, Kidney Diseases, Renal Cancer
- Trial name
- PODRACING (NCT06536439)
- Testing
- Pre-operative explanation of the procedure (DIPLANN + CT), Pre-operative surgical planning (DIPLANN + CT), RAPN (DIPLANN + CT)
- Where
- 5 sites in Belgium
- Volunteers
- 235 people
- Sponsor
- University Hospital, Ghent
Renal Cancer
Study to Compare Two Partial Nephrectomy Techniques for Renal Tumors: Robot-assisted vs Videolaparoscopic
Randomized, open-label clinical trial to compare renal volumetry pre and post operative in patients undergoing two types of partial nephrectomy techniques for renal tumors: robot-assisted vs videolaparoscopic.
- Trial name
- VPN x RANP (NCT06441851)
- Testing
- Videolaparoscopic Partial Nephrectomy, Robot-assisted Partial Nephrectomy
- Volunteers
- 50 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Kidney Neoplasm, Nephrectomy
Evaluation of 'RUS NE' in Robot-Assisted Partial Nephrectomy: Efficacy, Safety, and Stability
This study is a retrospective and prospective comparative study evaluating the efficacy, safety, and stability of the surgical navigation system 'RUS NE' in robot-assisted partial nephrectomy.
- Conditions
- Kidney Neoplasm, Nephrectomy, Surgical Navigation Systems, Renal Mass
- Trial name
- HTK_002 (NCT06945640)
- Testing
- RUS NE
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Hutom Corp
Renal Cell Carcinoma (Kidney Cancer)
Patient Reported Outcomes and Different Renal Artery Clamping Techniques During Robot Assisted Kidney Resection
The target population for this study consists of all patients undergoing kidney surgery at Haukeland University Hospital, Norway, with the primary focus being patients undergoing robot-assisted partial nephrectomy.
- Trial name
- RAPTOR (NCT07853001)
- Testing
- Standard clamping strategy, Early declamping strategy
- Where
- Norway
- Volunteers
- 130 people
- Sponsor
- Bjarte Almas
Upper Urinary Tract Urothelial Carcinoma, Kidney Preservation
Combination of DV and Tislelizumab for Renal Preservation in High-risk UTUC Patients
This is a prospective, open, multiple-center clinical study of renal preservation therapy in high-risk upper urinary tract urothelial carcinoma patients .
- Conditions
- Upper Urinary Tract Urothelial Carcinoma, Kidney Preservation, HER-2 ADC, PD-1antibody
- Trial name
- NCT05912816
- Testing
- RC48 Combined With Tislelizumab
- Where
- China
- Volunteers
- 20 people
- Sponsor
- RenJi Hospital
Kidney Neoplasm, Renal Mass up to 7cm
Hyperspectral Imaging in Robot-Assisted Partial Nephrectomy
The goal of this prospective observational study is to learn about the use of a novel imaging technique called hyperspectral imaging in adult participants who are having surgery for removing a tumor from their kidney.
- Trial name
- HSI-Renal (NCT07803315)
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University of Leipzig
Renal Cell Carcinoma, Renal Function Abnormal
The Cold Ischemia Robot-assisted Partial Nephrectomy
To establish evidence that cold ischemia, achieved through the use of ice slush, can improve the recovery from ischemia on the operated kidney in patients undergoing robot-assisted partial nephrectomy.
- Trial name
- NCT07326280
- Testing
- Cold ischemia robot-assisted partial nephrectomy, Warm ischemia robot-assisted partial nephrectomy
- Where
- China
- Volunteers
- 310 people
- Sponsor
- Sun Yat-sen University
Kidney Neoplasms / Surgery, Robotic Surgical Procedures
A Study of 3D Visualization Techniques to Improve the Quality and Safety of Robot-assisted Nephron Sparing Surgery for Complex Renal Tumors.
The goal of this clinical trial is to learn the evidence-based medical value of 3D visualization techniques to improve tumor control, preservation of renal function, and perioperative safety in robot-assisted nephron sparing…
- Conditions
- Kidney Neoplasms / Surgery, Robotic Surgical Procedures, Imaging, Three-Dimensional / Methods, Nephrectomy / Methods
- Trial name
- NCT06717009
- Testing
- Preoperative three-dimensional reconstruction
- Where
- China
- Volunteers
- 350 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital