Clinical trials: Particulate Matter
Blood Pressure, Lung Function
The Use of Air Cleaners to Mitigate Cardiopulmonary Health Impact of Indoor Exposure to Particles and Phthalates
This study aims to evaluate whether a short-term intervention strategy using air cleaner reduces indoor exposure to airborne particles (particulate matter with an aerodynamic diameter ≤2.5μm, PM2.5) and phthalates and improves…
- Conditions
- Blood Pressure, Lung Function, Inflammation, Oxidative Stress
- Trial name
- NCT03500614
- Testing
- Air cleaner use method 1, Air cleaner use method 2
- Where
- China
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Peking University
Inadequate or Impaired Respiratory Function
The Differential Pattern of Deposition of Nano Particles in the Airways of Exposed Workers
Investigation of the differences between the levels of extracellular and intracellular nano-particles in workers exposed to environmental particles during their employment to enhance understanding the process of penetration of…
- Trial name
- Nanoexposure (NCT01599845)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Cognitive Function, Cardiopulmonary Function
Commuter Air Pollution Intervention Study
Traffic related air pollution is a well-recognised and much studied contributor to smog and is linked to a number of adverse health outcomes.
- Conditions
- Cognitive Function, Cardiopulmonary Function, Saliva Stress Hormones, Air Pollution Exposure
- Trial name
- CAPI (NCT02277002)
- Testing
- Cabin Air Filtration
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Health Canada
Behavior Change
Evaluation of Report-Back Strategies for Long-term and Short-term Exposure Information in Rural Tribal Populations
The goal of this study is to evaluate different ways to provide feedback about environmental sampling results to participants. Specifically, the study will look at exposures with long-term risk (radon) and short-term risk (indoor…
- Trial name
- NCT06593340
- Testing
- Messenger 1, Messenger 2, Format 1
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Utah
Pneumococcal Carriage, Particulate Matter
Indoor Air Pollution (IAP) Carriage Study
Personal exposure to Indoor Air Pollution (IAP) is a known risk factor of severe pneumonia, which is the number one killer of children under five in developing countries.
- Trial name
- NCT01660659
- Testing
- Biomass Briquettes and Rocket stove
- Where
- The Gambia
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Pregnancy, Preeclampsia
Impact of Particulate Matter on Mothers and Babies in Antwerp (IPANEMA)
Introduction: An emerging body of evidence indicates that there is an association between air pollution exposure in pregnancy and adverse pregnancy outcomes (Rudra, Williams, Sheppard , Koenig, \& Schiff, 2011; Dadvand, et al.…
- Trial name
- IPANEMA (NCT02592005)
- Testing
- amount of fine dust and other environmental exposure
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Cardiopulmonary Function, Child
Health Benefits of Air Purifiers in Primary School Students
This study aims to explore changes in cardiopulmonary function and other health indicators in primary school students with the intervention of air purifiers on a randomized controlled trial.
- Trial name
- NCT05016271
- Testing
- Air purifier and fresh air ventilation systems with high-efficiency particulate air (HEPA) filters, Air purifier and fresh air ventilation systems without high-efficiency particulate air (HEPA) filters
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Fudan University
Autonomic Nervous System Imbalance, Blood Pressure
Short-term Cardiovascular Benefits of Wearing Particulate-filtering Respirators
An intervention study to assess the short-term cardiovascular effects of reducing personal air pollution exposure by wearing particulate filtering respirators.
- Conditions
- Autonomic Nervous System Imbalance, Blood Pressure, Inflammation, Vasoconstriction
- Trial name
- NCT02238028
- Testing
- Wear respirator
- Where
- China
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Fudan University
Cardiometabolic Health
Reducing Particulate Matter-associated Cardiovascular Health Effects for Seniors
Exposure to fine particulate matter (PM2.5) air pollution is an established risk factor for cardiovascular (CV) morbidity.
- Trial name
- RAPIDS2-Ypsi (NCT04103346)
- Testing
- air filtration with air purifier with hepa filter
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Air Pollution
Particulate Matter, Blood Pressure, and the Sympathetic Nervous System
Healthy volunteers will be exposed to ambient air near a roadway under the conditions of with and without a facemask and their responses will be evaluated.
- Trial name
- PM-SNS (NCT03079843)
- Testing
- exposure to particulate matter with N 95 facemask, exposure to particulate matter with no face mask
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Fetal Growth Restriction
A Randomized Air Filter Intervention Study of Air Pollution and Fetal Growth in a Highly Polluted Community
The purpose of this study is to use an air filter intervention to evaluate the relationship between particulate matter air pollution exposure during pregnancy and fetal growth.
- Trial name
- NCT01741051
- Testing
- HEPA Filter
- Where
- Mongolia
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Simon Fraser University
Asthma, Chronic Obstructive Pulmonary Disease
Measurement of Soluble Factors and Particulate Matter in Induced Sputum and EBC in Inflammatory Diseases of the Lung
In the present study inflammatory mediators will be isolated in induced sputum and exhaled breath condensate and will be correlated with particulate matter measured in these samples.Particulate matter will be assessed by partcle…
- Conditions
- Asthma, Chronic Obstructive Pulmonary Disease, Interstitial Lung Diseases, Occupational Lung Diseases
- Trial name
- NCT00511290
- Testing
- no generic names
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Inflammation, Sleep Deprivation
Circadian Rhythm Disruption Effects on Smoke Inhalation
Particulate matter exposure during smoke inhalation provokes inflammatory immune responses in people exposed to burning biomass including fire fighters and civilians.
- Conditions
- Inflammation, Sleep Deprivation, Circadian Rhythm Sleep Disorder, Shift Work Type, Smoke Inhalation
- Trial name
- NCT04955431
- Testing
- Sleep Restriction, Normal Sleep
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Montana
Beneficial Health Effects of Living in Filtered Air
Air Pollution Reduction in the Elderly and Cardiovascular and Cognitive Outcomes
Short-term and chronic exposure to ambient levels of particulate matter (PM) is associated with increased morbidity and mortality related to respiratory and cardiovascular disease.
- Trial name
- ELIFA (NCT02411240)
- Testing
- Air filtering
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Asthma
Correlation of Particulate Matter and Heme Oxygenase-1 Protein Activity in Asthmatic Children by Induced Sputum Analysis.
Samples of sputum from asthmatic children, between 5-17 years, will be collected during two years of the study period to perform tests Particle Size Distribution (PSD) and Shape Analysis (SA) of the particulate matter in the…
- Trial name
- NCT00969670
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Pneumonia, Chronic Obstructive Pulmonary Disease
Evaluation of Plasma Sphingosine-1-Phosphate as A Diagnostic and Prognostic Biomarkers of Community-Acquired Pneumonia
Pneumonia is a major infectious cause of death worldwide and imposes a considerable burden on healthcare resources. Obstructive lung diseases (COPD and Asthma) are increasingly important causes of morbidity and mortality…
- Conditions
- Pneumonia, Chronic Obstructive Pulmonary Disease, Asthma
- Trial name
- NCT03473119
- Where
- Taiwan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital
Air Pollution Exposure, Oxidative Stress
Savannah Environmental Nutrition Study (SENS): Nutrition Intervention to Reduce Air Pollution-Related Airway Inflammation and Oxidative Stress
This pilot clinical trial will evaluate the feasibility and potential health effects of a nutrition-based intervention among adults living in communities affected by air pollution near the Port of Savannah, Georgia.
- Conditions
- Air Pollution Exposure, Oxidative Stress, Airway Inflammation
- Trial name
- NCT07797413
- Testing
- Antioxidant- and Nutrient-Rich Food-Based Nutrition Intervention
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Georgia Southern University
Heart Rate, Heart Rate Variability
Air Pollution, Epigenetics and Cardiovascular Health: A Human Intervention Trial
In this study, the pills formulated are being used to try to ameliorate the effect of air pollution on epigenetic changes, specifically DNA methylation, potentially linked with particulate matter air pollution inhalation and…
- Conditions
- Heart Rate, Heart Rate Variability, Inflammation
- Trial name
- EPI-Air (NCT01864824)
- Testing
- methyl donor
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Endothelial Dysfunction
Combustion Derived Air Pollution and Vascular Function
Air pollution is a major cause of cardiovascular morbidity and mortality. The components of air pollution responsible and the mechanisms through which they might mediate these harmful effects remain only partially understood.
- Trial name
- NCT00775099
- Testing
- Forearm Vascular Study, Badimon Chamber
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Pollution; Exposure, Hypertension
Solar Lighting to Reduce Indoor Air Pollution in Rural Uganda
This study evaluates the impact of a solar lighting system on kerosene lamp use, levels of indoor air pollution, and health in women living in rural Uganda.
- Conditions
- Pollution; Exposure, Hypertension, Pollution Related Respiratory Disorder
- Trial name
- NCT03351504
- Testing
- Solar lighting system
- Where
- 2 sites in United States, Uganda
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital