Clinical trials: Parturition
Infection, Soft Tissue, Infection, Wound
Direct Antibiotic Delivery of Cefazolin Into Soft Tissue Infections Using Subcutaneous Injection and Ultrasonic Dispersion
This study focuses on a new drug delivery system (Direct Antibiotic Delivery) to treat soft tissue infections. In this study, cefazolin is delivered directly to the target tissues using subcutaneous injection of antibiotic…
- Conditions
- Infection, Soft Tissue, Infection, Wound, Cellulitis, Diabetic Foot Ulcer
- Trial name
- DAD (NCT01238276)
- Testing
- Cefazolin, Silberg Tissue Preparation System
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sonescence, Inc.
Labor Onset and Length Abnormalities, 37 or More Completed Weeks of Gestation
Comparative Study Between Using WHO Labour Care Guide & Modified WHO Partograph
This randomized clinical trial is based on comparing the efficiency of modified WHO partographs vs. the new WHO labour care guide in monitoring and assessing the outcome of labour.
- Conditions
- Labor Onset and Length Abnormalities, 37 or More Completed Weeks of Gestation, First Birth
- Trial name
- NCT06537089
- Testing
- Supportive care measures, LCG guided labour interference
- Where
- Egypt
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Hend Mahmoud Abdelghany
Pain, Fatigue
Kinesio Taping and Foot Massage for Post-Cesarean Recovery
After a cesarean section, postpartum women may experience pain, fatigue, and various negative mood disturbances. These effects pose a significant public health concern by threatening both maternal and infant health.
- Conditions
- Pain, Fatigue, Mood (Psychological Function), Postpartum Women
- Trial name
- NCT06811285
- Testing
- Kinesiological Taping, Foot Massage Group
- Where
- Turkey (Türkiye)
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Uşak University
Insulin Resistance
Intramyocellular Fatty Acid Trafficking in Insulin Resistance States - Effects of Intestinal Delivery of Lipids
Muscle insulin resistance is a hallmark of upper body obesity (UBO) and Type 2 diabetes (T2DM). It is unknown whether muscle free fatty acid (FFA) availability or intramyocellular fatty acid trafficking is responsible for muscle…
- Trial name
- NCT03818178
- Testing
- Intralipid, Palm Oil Emulsion, Saline
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Hypoxia
Comparison of Two Pulse Oximeters in Delivery Room
Time to stable reading of oxygen saturation at the delivery room will be compared between two different devices.
- Trial name
- NCT02704585
- Testing
- Nellcor, Masimo
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
Birth, Fear of Childbirth
Training Given in the Line of Coping With Fear of Birth on Fear of Birth Birth Experience
Pregnancy and childbirth are a natural life event for women, as well as a process in which physical, biological and psychosocial changes are experienced.
- Conditions
- Birth, Fear of Childbirth, Education, Pregnancy
- Trial name
- NCT05928117
- Testing
- Education
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Third Stage of Labor, Bleeding
The Effect of Guided Imagery on the Third Stage of Labor
The purpose of this study was to evaluate the effect of guided imagery on the third stage of labor. Blood loss from hemorrhage during childbirth, most commonly due to uterine atony, is one of the leading causes of maternal…
- Conditions
- Third Stage of Labor, Bleeding, Guided Imagery, Childbirth
- Trial name
- NCT00826735
- Testing
- Guided imagery
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Vanderbilt University
Delivery Problem, Childrearing
Perineal Massage Performed During the Labour
In this study, perineal massage was applied to primiparous women who did not give birth before, as a quasi-experimental control group to determine the effects of massage on birth comfort, perineal trauma and perineal pain.
- Conditions
- Delivery Problem, Childrearing, Satisfaction, Patient, Perineum; Injury
- Trial name
- NCT05962918
- Testing
- Perinal massage
- Where
- Turkey (Türkiye)
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Munzur University
Gestational Diabetes Mellitus in Childbirth, Neurodevelopmental Disorders
Early Biomarkers of Neurodevelopment in Offspring of Diabetic Mothers
The prospective multicenter study GD-Brain provides a better knowledge on the basis of neurological impairment in children born to mothers with gestational diabetes (GDM).
- Trial name
- GD-BRAIN (NCT03032991)
- Where
- Spain
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
New Born
Impact of Physical Activity During Pregnancy on Biological Markers at Birth in Cord Blood (CORDOMOUV)
Currently, an interventional protocol for physical activity during pregnancy is underway at the Clermont University Hospital (PREGMOUV study).
- Trial name
- CORDOMOUV (NCT07579468)
- Testing
- physical activity level during pregnancy
- Where
- France
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Wound Infection
Catheterization During Second Elective Caesarean Delivery
Use versus non use of urinary catheterization during Second Elective caesarean delivery:
- Trial name
- CDSECD (NCT02143089)
- Testing
- Foley's Catheter
- Where
- Egypt
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Infertility, Fertility Disorders
Live Birth Rate After Sperm Selection Using ZyMōt Multi (850µL) Device for Intra Uterine Insemination
This single centre interventional pilot randomized control study intends to compare two methods of sperm preparation for couples referred for Intra Uterine Insemination (IUI) procedure.
- Trial name
- FERTINSEM (NCT06144268)
- Testing
- ZyMōt Multi (850µL), Density Gradient Centrifugation
- Where
- Belgium
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Anastomosis, Roux-en-Y, Surgical Operation With Anastomosis, Bypass or Graft
Comparison of Laparoscopic Traditional and Knotless Sutures
Background Excess weight and obesity is the fifth leading risk factor for global death. Bariatric surgery is considered as the only effective long-term treatment for morbid obesity.
- Trial name
- NCT02720718
- Testing
- Stratafix, Vicryl
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- AZ St.-Dimpna Geel
Prematurity, Neonatal Screening
Amino Acid and Acylcarnitine Profiles in Premature Neonates
Primary Hypotheses of the study include: Metabolic profiles are influenced by gestational age, chronological age, type and degree of nutritional support and illness Metabolic profiles differ between neonates who receive…
- Conditions
- Prematurity, Neonatal Screening, Parenteral Nutrition
- Trial name
- NCT00865150
- Where
- 2 sites in United States
- Volunteers
- 1,003 people, healthy volunteers welcome
- Sponsor
- Pediatrix
Pregnancy Outcome, Gestational Weight Gain
The Effect of Individualized Exercise Guidance on Pregnancy Outcome
A single center, randomized controlled trial was conducted to investigate whether individualized exercise guidance was more effective in improving pregnancy outcomes in normal pregnant women.
- Conditions
- Pregnancy Outcome, Gestational Weight Gain, Mediation, Macrosomia, Fetal
- Trial name
- NCT05760768
- Testing
- Individualized exercise guidance
- Where
- China
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Perinatal Outcome
Severing Nuchal Cord at the Time of Delivery.
Umbilical cord often becomes encircled around portions of the fetus, usually the neck. The incidence ranges from 1 loop in 21% to 3 loops in 0.2%.
- Trial name
- NCT00345254
- Testing
- severing cord
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Preterm Birth
Effectiveness of Targeted Cervical Length Screening Guided by a Preterm Birth Risk Scoring System in Reducing the Rate of Preterm Birth
This cluster non-randomized controlled trial aims to evaluate the effectiveness and feasibility of a risk score-guided targeted cervical length screening strategy for the prevention of spontaneous preterm birth in routine…
- Trial name
- NCT07415070
- Testing
- Preterm birth risk scoring system, Transvaginal ultrasound cervical length measurement, Vaginal Progesterone
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Ningbo University
Oxygen Delivery Systems at Altitude
Aviation Portable Oxygen Delivery System
This study aims to investigate dose based oxygen delivery vs. continuous flow of oxygen during simulated altitude conditions as would be experienced after a loss of pressure during commercial aircraft flight.
- Trial name
- NCT03425409
- Testing
- Integra Pulse Portable- Continuous flow, Integra Pulse Portable- Pneumatic pulsed flow
- Volunteers
- healthy volunteers welcome
- Sponsor
- Duke University
Healthy Participants
A Study to Assess the Bioequivalence of Trastuzumab Via Different Subcutaneous Delivery Platforms in Healthy Male Participants
This two-part study will evaluate the bioequivalence, safety, and tolerability of a single SC dose of trastuzumab administered via handheld syringe/syringe pump (HHS/SP) with infusion set (IS) and an on-body delivery system…
- Trial name
- NCT07214766
- Testing
- Trastuzumab
- Where
- 4 sites in United States
- Volunteers
- 331 people, healthy volunteers welcome
- Sponsor
- Genentech, Inc.
Labor Hopscotch
The Effect of Labour Hopscotch Based Midwifery Care in Labor
This study aimed to evaluate the effects of labor hopscotch midwifery care on birth outcomes, labor pain, birth comfort and satisfaction. The research is a randomized controlled experimental design.
- Trial name
- NCT06879405
- Testing
- The Labor Hopscotch
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ataturk University
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