Clinical trials: Pathologic Processes
Postpartum Hemorrhage
Uterine Massage After Vaginal Delivery
The participants will be randomized into an oxytocin plus uterine massage group and an oxytocin-only group in the third stage of the labor.
- Trial name
- NCT03858569
- Testing
- active management of third stage of labor
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Human Immunodeficiency Virus, STDs
Computer-Assisted Tailored Cue-card Health [CATCH] Study
This study will draw from proven interventions to refine and pilot test a cue card driven computer-assisted intervention, along with HIV/STI testing, that will be tailored to each participant's demographic characteristics, risk…
- Conditions
- Human Immunodeficiency Virus, STDs, Hepatitis, Viral, Human
- Trial name
- CATCH (NCT01170741)
- Testing
- Tailored Cue Cards
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- RTI International
Chronic Kidney Disease
Does a Mainstream Summer Camp Experience Improve Pediatric Kidney Patients' Physical Fitness and Self Concept?
Purpose: Most children and adolescents with chronic kidney disease (CKD) have much less physical endurance than their age matched peers, are at high risk for premature cardiovascular disease, and have a poor self image in part…
- Trial name
- NCT02803541
- Testing
- 12 day mainstream summer camp experience
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Endometriosis, Pelvic Pain
Efficacy of Manual Therapy to Improve Quality of Life and Decrease Pain in Subjects With Endometriosis
This study will compare subjects with a history of pelvic or menstrual pain diagnosed with endometriosis treated at Clear Passage with untreated control subjects.
- Conditions
- Endometriosis, Pelvic Pain, Dysmenorrhea
- Trial name
- Endo2017 (NCT03118154)
- Testing
- Manual Physical Therapy
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Clear Passage Therapies, Inc
Infectious Disease, Bacterial Infections
Safety & Efficacy of an Antibacterial Protein Molecule Applied Topically to the Nostrils of Volunteers and Patients
The purpose of this study is to determine whether the antibacterial protein P128 is (i) safe and well tolerated in healthy volunteers and in chronic kidney diseases patients on dialysis, (ii) is it effective in reducing the nasal…
- Trial name
- NCT01746654
- Testing
- P128-0.1 mg, P128-0.3 mg, P128-1.0 mg
- Where
- Singapore
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- GangaGen, Inc.
Genetic Predisposition
Simultaneous tDCS and Computerised Gamified Short-term Memory Task Feasibility
The goal of this observational study is to gain insight into the effects of transcranial direct current stimulation (tDCS) on short-term memory task performance and the feasibility of tDCS in overtly healthy carriers of the…
- Trial name
- ACTTDCS-FG (NCT06402266)
- Testing
- tDCS
- Where
- Denmark
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Pulmonary Disease, Chronic Obstructive
ScreenFlow: Strategy for Finding Cases of Moderate-to-Severe COPD
ScreenFlow is a chronic obstructive pulmonary disease (COPD) screening tool currently being studied and iteratively developed that incorporates a questionnaire administered on a tablet and data from a digital peak flow meter to…
- Trial name
- NCT02753556
- Volunteers
- 399 people, healthy volunteers welcome
- Sponsor
- Dimagi Inc.
Adhesion, Tooth
Immediate and Delayed Dentin Sealing Effect on Partial Crowns
Immediate Dentin Sealing as an adjunct to adhesive cementation of all ceramic restorations is proposed and executed in several studies, but there is very limited evidence to support its effectiveness.
- Conditions
- Adhesion, Tooth, Crown, Luting
- Trial name
- NCT03443583
- Testing
- Immediate Dentin Sealing or Delayed Dentin Sealing
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Pre-diabetes
Glycemic Effects of Honey
Honey has been used as a sweetener for centuries. Recent data indicate that honey consumption may have beneficial effects upon glucose intolerance, a health issue currently affecting 57 million Americans of every age and…
- Trial name
- NCT01371266
- Testing
- Honey, High Fructose Corn Syrup 55 (HFCS 55), CHO (sugar)
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Cicatrix, Carbon Dioxide Laser
Interventional Study to Evaluate the Appearance of Surgical Scars After Laser Therapy
This study evaluates the effect of a fractionated carbon dioxide laser on surgical scars of the face and neck over 12 months. Anyone with a surgical scar on the face and neck who has not had laser therapy may be eligible to…
- Trial name
- NCT02985151
- Testing
- Syneron-Candela CO2RE Laser
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Atrial Fibrillation; Stroke Prevention
Stroke Prevention in Atrial Fibrillation Patients Between 2004 and 2020
Prevention of thromboembolic complications is an important part in the management of patients with atrial fibrillation (AF). European and American guidelines recommend the use of non-vitamin K antagonist oral anticoagulants…
- Trial name
- NCT04686045
- Testing
- observational study
- Where
- 2 sites in Poland
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Jan Kochanowski University
Parkinson Disease
Role of Nasal Dysbiosis in Parkinson Disease
Olfactory dysfunction is frequent in Parkinson Disease (PD) and may be present years before the motor symptoms appear. The early olfactory dysfunction could result from environmental factors acting through the nasal cavity such…
- Trial name
- SMELLPARK (NCT04249245)
- Testing
- Nasal Swab
- Where
- 2 sites in France, Guadeloupe
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Blood Loss
The MAR Method Versus the Visual Estimation Method in Predicting External Blood Loss
The goal of this educational clinical trial is to determine whether the MAR method is more effective than the Visual Estimation method for estimating blood loss.
- Trial name
- NCT06855472
- Testing
- The MAR method
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- Betül Akbuğa Özel
Myotonic Muscular Dystrophy
Study of Muscle Wasting and Altered Metabolism in Patients With Myotonic Dystrophy
OBJECTIVES: I. Examine the interrelationships between muscle wasting (phenotype), the degree of myotonic dystrophy (DM) gene expression (genotype) in patients with DM. II. Characterize the insulin resistance in these patients.
- Trial name
- NCT00004769
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Caesarean Wound, Hypertrophic Surgical Scar
: Protescal: Prevention of Hypertrophic Scar and Keloid Formation Post Caesarean Section
This study aimed to evaluate the effectiveness of Protescal in preventing post caesarean section hypertrophic scar and keloid formation.
- Conditions
- Caesarean Wound, Hypertrophic Surgical Scar, Keloid Scar Following Surgery
- Trial name
- NCT04951869
- Testing
- Protescal gel
- Where
- Malaysia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Diabetic Foot, Diabetic Foot Ulcer
SkinTE™ in the Treatment of Diabetic Foot Wounds
This study is a prospective, multi-center, randomized controlled trial designed to collect patient outcome data on a commercially available human autologous homologous skin construct with SOC dressing compared to SOC dressings…
- Conditions
- Diabetic Foot, Diabetic Foot Ulcer, Ulcer Foot
- Trial name
- NCT03881254
- Testing
- Human Autologous Homologous Skin Construct, Additional Outer Dressing Applicaiton, Offloading
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- PolarityTE
Inflammation, Smoking Cessation
Screening and Multiple Intervention on Lung Epidemics
This prospective randomized pilot trial will evaluate a multiple intervention program of prevention in lifelong smokers aiming at reduction of chronic inflammation status through treatment with low-dose acetylsalicylic acid…
- Conditions
- Inflammation, Smoking Cessation, Diet Modification, Physical Activity
- Trial name
- SMILE (NCT03654105)
- Testing
- Cytisine, Acetylsalicylic acid, Diet Modification and Physical Activity Increase
- Where
- Italy
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Osteoarthritis Shoulder, Avascular Necrosis of the Head of Humerus
Catalyst CSR Shoulder System for Semi or Total Shoulder Arthroplasty
Evaluation of the performance and safety of the Catalyst CSR Shoulder System with clinical and radiographic results at multiple time points through 24 months postoperatively This study will be a prospective multi-center study…
- Conditions
- Osteoarthritis Shoulder, Avascular Necrosis of the Head of Humerus, Rheumatoid Arthritis Shoulder
- Trial name
- NCT04968405
- Testing
- Catalyst CSR Total Shoulder System
- Where
- 3 sites in United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Catalyst OrthoScience
Cerebral Small Vessel Diseases, Cerebral Small Vessel Ischemic Disease
Cambridge 7 Tesla Cerebral Small Vessel Disease Study
CamSVD is jointly sponsored by the University of Cambridge and Cambridge University Hospitals NHS Foundation Trust. We aim to explore and understand the underlying arterial pathology in Cerebral Small Vessel Disease (SVD) using…
- Conditions
- Cerebral Small Vessel Diseases, Cerebral Small Vessel Ischemic Disease, Lacunar Stroke
- Trial name
- CamSVD (NCT04330222)
- Testing
- 7 Tesla Magnetic Resonance Imaging, Brief Memory and Executive Test
- Where
- United Kingdom
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Cambridge
Healthy, Wrinkle
Safety and Efficacy Study of Vasu Facial Beauty Oil
This is an open-label, single-arm, single-center, proof-of-concept, exploratory, safety and efficacy, clinical study of a Vasu Facial Beauty Oil in healthy adult human subjects.
- Conditions
- Healthy, Wrinkle, Dry Skin, Skin Pigment
- Trial name
- NCT05646953
- Testing
- Facial Beauty Oil
- Where
- India
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- NovoBliss Research Pvt Ltd