Clinical trials: Patient Specific Implant
Malocclusion
Finite Element Modelling of Le Fort I Osteotomy Fixation : PSI vs Miniplates
This study aimed to evaluate the biomechanical performance of patient-specific versus conventional fixation for Le Fort I osteotomy using subject-specific finite element models derived from real surgical plans.
- Trial name
- NCT07365657
- Testing
- In silico orthognathic surgery with customized implants digital only on 3D scanners
- Where
- France
- Volunteers
- 2 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Cartilage Damage, Knee Injuries
Clinical Trial of an MRI Based Patient Specific Focal Knee Resurfacing Implant
The goal of this study is to evaluate the efficacy, safety and performance of the Episealer® device in a sample size of 30 patients and on the long term (10 years follow-up).
- Trial name
- Episealer2 (NCT03755388)
- Testing
- Episealer
- Where
- Belgium
- Volunteers
- 4 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Hemifacial Microsomia, Mucormycosis
Clinical Evaluation of Patient-Specific 3D-Printed Titanium Implants for Facial Reconstruction.
This clinical study aims to evaluate the effectiveness of patient-specific 3D-printed titanium facial implants in the reconstruction and aesthetic correction of facial defects.
- Conditions
- Hemifacial Microsomia, Mucormycosis, Oral Squamous Cell Carcinoma, Microgenia
- Trial name
- 3DFACE (NCT07654647)
- Testing
- Patient-specific titanium implants for facial reconstruction
- Where
- Syria
- Volunteers
- 30 people
- Sponsor
- Latakia University
Pulmonary Disease, Chronic Obstructive
Evaluating the Clinical Effectiveness of a Patient-specific Silicone Stent
The goal of the trial is to establish a method, material, and patient-specific stent design that will last longer, fit better, and cause less trauma to the airway and the patient.
- Trial name
- NCT05050591
- Testing
- Patient-Specific Silicone Airway Stent
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- VisionAir Solutions
Unspecified Adult Solid Tumor, Protocol Specific
Satisfaction With Placement of Implantable Venous Access Devices in Patients With Solid Tumors
RATIONALE: Gathering information about patients with solid tumors who have implantable venous access devices may help doctors learn more about patient satisfaction.
- Trial name
- NCT01098643
- Testing
- computer-assisted intervention, medical chart review, questionnaire administration
- Where
- 2 sites in United States
- Volunteers
- 88 people
- Sponsor
- Vanderbilt University
Unspecified Adult Solid Tumor, Protocol Specific, Vascular Access Device Complications
Study Comparing Two Types of Ports in Patients With Cancer Receiving Intravenous Chemotherapy
RATIONALE: Giving chemotherapy drugs through an implanted port reduces the need for multiple needle sticks. It is not yet known whether one type of port is more effective than another in reducing infections and other side effects…
- Trial name
- NCT00607880
- Testing
- vascular access device placement
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
Recurrent Dislocation of Temporomandibular Joint (Disorder)
Evaluation of Using Patient Specific Zirconium Dioxide Implant Versus Patient Specific Titanium Implant in Treatment of Chronic Condylar Dislocation
Alternate hypothesis that treatment of Tempromandibular joint dislocation with Zirconium Dioxide eminoplasty will be more efficient than using titanium onlays in terms of decreasing maximum inter incisal distance and providing…
- Trial name
- NCT05377593
- Testing
- eminoplasty with patient specific Zirconium dioxide onlay implant
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Cairo University
Immediate Implant Placement in Mandibular Molar Extraction Sockets
3D-Printed PLA Guide Versus Resin Guide in Mandibular Molar Implant Placement
This randomized clinical trial compares two tooth-supported computer-guided surgical guide systems for immediate implant placement in mandibular molar extraction sockets: a patient-specific 3D-printed PLA guide system and a…
- Trial name
- CGIIPMM-PLA-MR (NCT07826039)
- Testing
- immediate implant placement using PLA guide, Immediate implant placement using Modified resin guide.
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Mohamed Esmail Ahmed Hassan
Blow-Out Fractures, Orbital Fractures
Accuracy& Orbital Volume Using Patient Specific Titanium Implant Vs Zirconia for Orbital Floor Reconstruction
Comparative study used to assess if the patient specific zirconia implant will provide better accuracy, intraoperative adaptability, precise orbital volume and soft tissue reaction with more cost effectiveness than the patient…
- Conditions
- Blow-Out Fractures, Orbital Fractures, Orbital Floor Fracture, Orbital Trauma
- Trial name
- NCT06369129
- Testing
- Orbital floor reconstruction with Patient Specific Zirconia Implant, Orbital floor reconstruction with Patient Specific Titanium Implant
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Knee Osteoarthritis
A Prospective Study to Evaluate the iTotal Knee and iPoly XE Tibial Inserts
This study is designed to evaluate the clinical outcomes of subjects who have recently undergone surgery with the iTotal® Cruciate Retaining (CR) Total Knee Replacement System (KRS) who have also had iPoly XE Tibial Inserts…
- Trial name
- NCT03289754
- Testing
- iPoly XE tibial insert with ConforMIS iTotal KRS
- Where
- Germany
- Volunteers
- 52 people
- Sponsor
- Restor3D
Sleep Apnea Syndrome (OSAS), Orthognathic Surgical Procedures
Splintless Versus Conventional Maxillomandibular Advancement Surgery for Obstructive Sleep Apnea
The goal of this clinical trial is to find out whether using a splintless surgical approach improves the accuracy of maxillomandibular advancement (MMA) surgery for treating obstructive sleep apnea (OSA) in adults.
- Conditions
- Sleep Apnea Syndrome (OSAS), Orthognathic Surgical Procedures, Sleep Apnea - Obstructive
- Trial name
- SvCMAS (NCT07598461)
- Testing
- Splintless MMA surgery, Splint MMA surgery
- Where
- Netherlands
- Volunteers
- 66 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Abnormality of Facial Skeleton
Radiographic Assessment of Three Dimensional Mandibular Position Using Splint-less Patient Specific Implant
The purpose of this study was to assess the accuracy of a splint-less approach for mandibular jaw orthognathic surgery. This approach utilized a personalized orthognathic surgical guide (POSG) system, which comprised a set of…
- Trial name
- NCT06160661
- Testing
- mandibular saggital split osteotomy
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Significant Bone Defect in the Orbit
Efficiency of 3D-printed Implant Versus Autograft for Orbital Reconstruction (TOR-3D)
Two scenarios may result in significant bone defect in the orbit: surgical oncology (meningioma, cancers of the upper aerodigestive tract) or severe trauma.
- Trial name
- TOR-3D (NCT03608280)
- Testing
- Bone autograft, Orbital reconstruction by 3D-printed porous titanium implant
- Where
- France
- Volunteers
- 92 people
- Sponsor
- Hospices Civils de Lyon
Dental Phobia, Disabilities Multiple
Evaluation of Implant Therapies Performed Under General Anesthesia in Patients With Specific Dental Needs
Implant placement is the solution of choice for replacing missing teeth in a fixed way. However, dental practitioners and surgeons are reluctant to place implants in the population of patients with special needs.
- Conditions
- Dental Phobia, Disabilities Multiple, Complex Medical Health Condition
- Trial name
- NCT05153538
- Where
- France
- Volunteers
- 57 people
- Sponsor
- University Hospital, Clermont-Ferrand
Knee Arthroplasty, Total
iTotal Pilot Study of ConforMIS Custom Total Knee Implant
To compare the outcomes of patients receiving the ConforMIS custom total knee implant to the outcomes of patients who receiving an off-the-shelf total knee implant.
- Trial name
- NCT02186587
- Testing
- ConforMIS custom total knee
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Missouri-Columbia
Atrophic Edentulous Maxilla
Patient-specific Finite Element Analysis of Immediate Loading in the Edentulous Maxilla: Comparison of Three Implant Configurations Using Digital Twins.
Rehabilitation of severely atrophic edentulous maxillae with dental implants pose a significant clinical challenge. Immediate loading in grafted bone is often debated due to concerns about stress distribution and…
- Trial name
- NCT07266896
- Testing
- numerical study
- Where
- France
- Volunteers
- 1 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Metastatic Cancer, Unspecified Adult Solid Tumor, Protocol Specific
Carmustine Implants in Treating Patients With Brain Metastases
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving the drugs in different ways may kill more tumor cells.
- Trial name
- NCT00003878
- Testing
- polifeprosan 20 with carmustine implant, conventional surgery
- Where
- 11 sites in United States
- Sponsor
- New Approaches to Brain Tumor Therapy Consortium
Implant Stability, Root Analog Implant
Stability of Patient-specific Root-analogue Implants and Conventional Root-form Implants for Treating Non-restorable Single-rooted Maxillary Teeth
its a experimental study comparing between the stability of immediate root fomed implant versus the conventional titanium implant
- Conditions
- Implant Stability, Root Analog Implant, Conventional Root Form Implant, Non Restorabl Teeth
- Trial name
- NCT03689933
- Testing
- Root analog implant
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cranial Bone Defect, Orbital Base Fracture
Clinical Study of FRC Implant to Treat Skull Bone Defects
Bioactive fibre-reinforced composite implant is used for reconstruction of skull bone defects and orbital floor defects. Functional and aesthetic outcome is assessed by patient and doctor.
- Trial name
- Cranio-2 (NCT01874613)
- Testing
- FRC implant reconstruction
- Where
- Finland
- Volunteers
- 19 people
- Sponsor
- Turku University Hospital
Aortic Stenosis, Gender
TAVI and Gender Outcomes Aortic Stenosis Undergoing Transfemoral Transcatheter Aortic Valve Implantation.
Severe aortic stenosis (AS) is the commonest form of valvular abnormality in the developed world and transcatheter aortic valve implantation (TAVI) is now widely practiced as in many cases is the preferred treatment option over…
- Conditions
- Aortic Stenosis, Gender, Surgery
- Trial name
- NCT04915976
- Volunteers
- 14,086 people, healthy volunteers welcome
- Sponsor
- Imperial College Healthcare NHS Trust