Clinical trials: Patient Ventilator Interactions
Obesity, Non Invasive Ventilation
Patient-ventilator Interactions in Long Term Non-invasive Ventilation: Influence of Back-up Frequency
In patients under bi-level pressure support ventilation for obesity hypoventilation syndrome, this study aims to determine if it is better, in terms of efficacy and patient-ventilator synchronisation to use Spontaneous mode (S)…
- Trial name
- NCT01130090
- Testing
- Adjustment of back-up respiratory rate on bi-level ventilator
- Where
- Switzerland
- Volunteers
- 10 people
- Sponsor
- Ligue Pulmonaire Genevoise
Dyspnea
Validation of an Observational Scale of Dyspnea in Non-communicating Patients in the ICU
Background : Dyspnea is common and severely impact mechanically ventilated patients outcomes in intensive care unit (ICU). Recognize, measure and treat dyspnea have become current major therapeutic challenge.
- Trial name
- DYS-NOC (NCT02801838)
- Testing
- Morphine
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil
Mechanical Ventilation Complication
Automated Detection of Patient Ventilator Asynchrony Using Pes Signal
Rationale: Patient-ventilator asynchrony (PVA) in mechanical ventilation is associated with adverse patient outcome such as a prolonged stay in the ICU and even mortality.
- Trial name
- NCT06186557
- Testing
- No intervention
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Leiden University Medical Center
Acute Respiratory Failure
Adjusted Ventilatory Assist (NAVA-NIV) in Infants: Short-term Physiological Study
Neurally Adjusted Ventilatory Assist (NAVA) is a new form of partial support wherein the machine applies positive pressure throughout inspiration in proportion to the electrical activity of the diaphragm (EAdi), as assessed by…
- Trial name
- NCT02043990
- Testing
- Noninvasive NAVA ventilation
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Acute Hypercapnic Respiratory Failure
Sedation During Noninvasive Ventilation (NIV)
In patients undergoing NIV for acute respiratory, lack of tolerance is one of the main reason of failure. This may result in a poor synchrony between the patient and the machine, leading to gross mismatching and potentially to an…
- Trial name
- REMI (NCT02264626)
- Testing
- Remifentanil
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Patient Ventilator Interactions, Spontaneous Breathing Trial
Entropy Analysis and Complex Patient-ventilator Interactions During Mechanical Ventilation
Complex patterns of patient-ventilator interactions could be miscalculated by visual observation of mechanical ventilator screens or current algorithms based on physiologic waveforms to detect patient-ventilator asynchronies.
- Trial name
- ENTROPY-ICU (NCT04128124)
- Testing
- processing signals of airway pressure and airway flow to calculate entropy
- Where
- Spain
- Volunteers
- 107 people
- Sponsor
- Corporacion Parc Tauli
Mechanical Ventilation, Patient-Ventilator Asynchrony
Patient-Ventilator Asynchrony: Occurence and Clinical Impact in Usual Care
The goal of this observational study is to unravel the occurence, impact and relations of Patient-Ventilator Aynchrony (PVA) in mechanically ventilated patients.
- Trial name
- PVA-detection (NCT07624786)
- Testing
- PVA classification software
- Where
- 3 sites in Netherlands
- Volunteers
- 110 people
- Sponsor
- Erasmus Medical Center
Chronic Obstructive Pulmonary Disease
Patient-Ventilator Interactions in Chronic Obstructive Pulmonary Diseases (COPD) Under Non-Invasive Ventilation
Non-invasive ventilation (NIV) in severe hypercapnic Chronic Obstructive Pulmonary Diseases (COPD) may be associated - during sleep - with recurrent episodes of patient ventilatory asynchrony, which in turn may affect quality of…
- Trial name
- NCT01180439
- Testing
- Adjustment of ventilator settings (device)
- Where
- Switzerland
- Volunteers
- 8 people
- Sponsor
- Ligue Pulmonaire Genevoise
Chronic Hypercapnic Respiratory Failure, Obesity Hypoventilation Syndrome
Patient -Ventilator Interaction in Chronic Respiratory Failure
To evaluate a novel advanced physiological monitoring system to improve nocturnal non-invasive ventilation (NIV) in Neuromuscular disease (NMD), Chest wall disease (CWD), Chronic Obstructive Pulmonary Disease (COPD) and Obesity…
- Conditions
- Chronic Hypercapnic Respiratory Failure, Obesity Hypoventilation Syndrome, Neuromuscular Disease, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT01371149
- Testing
- Surface parasternal electromyography (EMG) set up
- Where
- 2 sites in United Kingdom
- Volunteers
- 58 people
- Sponsor
- Michelle Ramsay
Ventilator Weaning, Respiration, Artificial
Two Cycling Off Modes in Pressure Support: Study of Respiratory Mechanics, Breathing Comfort and Asynchrony Patterns
Objective: To compare termination criteria (TC) of pressure support ventilation (PSV). Design: Randomized cross-over clinical trial. Setting: Intensive Care Units.
- Trial name
- NCT00910286
- Testing
- Pulmonary Ventilator
- Where
- Brazil
- Volunteers
- 18 people
- Sponsor
- Hospital de Clinicas de Porto Alegre