Clinical trials: Patient With Colorectal Cancer
Rectal Cancer
Neoadjuvant Chemoradiation With RHUMAB VEGF (Avastin) for Rectal Cancer
Preoperative chemoradiation leads to increased pelvic control and overall survival, but both distant and local disease control remain problematic in locally advanced rectal cancer patients.
- Trial name
- NCT00113230
- Testing
- Avastin (Bevacizumab, RHUMAB VEGF), Capecitabine, Radiation Therapy
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Colorectal Cancer, Colorectal Cancer Metastatic
Possible Association of Intestinal Helminths and Protozoa With Colorectal Cancer Pathogenesis
Colorectal cancer (CRC) has the third highest cancer incidence in the world. There is mounting evidence that the intestinal microbiota plays an important role in colorectal carcinogenesis.
- Conditions
- Colorectal Cancer, Colorectal Cancer Metastatic, Intestinal Parasite, Protozoan Infections
- Trial name
- NCT03173001
- Testing
- Parasitological examination
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Research Institute of Epidemiology, Microbiology and Infectious Diseases, Uzbekistan
Colorectal Cancer (CRC)
Fecal Immunochemical Test in Diagnosing Colorectal Cancer Among Vietnamese Patients with Lower Gastrointestinal Symptoms
The goal of this clinical trial is to evaluate the diagnostic value of fecal immunochemical tests (FIT) in identifying colorectal cancer (CRC) among Vietnamese individuals presenting with lower gastrointestinal symptoms.
- Trial name
- NCT06776120
- Testing
- Fecal chemical test (FIT)
- Where
- Vietnam
- Volunteers
- 1,575 people, healthy volunteers welcome
- Sponsor
- Luu Ngoc Mai
Neoplasms
A Study of Irinotecan With Dabrafenib Plus Trametinib and Anti-EGFR in the Second Line of Therapy in People With Metastatic Colorectal Cancer
The purpose of this study is to evaluate the efficacy and toxicity of irinotecan with dabrafenib, cetuximab/panitumumab in the second line of treatment for the potential treatment of colorectal cancer that: has a metastatic…
- Trial name
- NCT06967155
- Testing
- • Drug: Dabrafenib • Drug: Trametinib • Drug: Cetuximab • Drug: Рanitumumab • Drug: Oxaliplatin • Drug: Irinotecan • Drug: Leucovorin • Drug: 5-FU
- Where
- Russia
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Blokhin's Russian Cancer Research Center
Bladder Carcinoma, Breast Carcinoma
PatientCareAnywhere Internet-Based Software in Improving Communication and Education in Patients With Cancer and Their Healthcare Providers
This partially randomized pilot clinical trial develops and studies a software program, called PatientCareAnywhere, to see whether it can help patients communicate with their doctors and other healthcare providers, and educate…
- Conditions
- Bladder Carcinoma, Breast Carcinoma, Colorectal Carcinoma, Lung Carcinoma
- Trial name
- NCT02408406
- Testing
- Communication Intervention, Educational Intervention, Internet-Based Intervention
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Colorectal Cancer Screening, Diabetes Mellitus, Type 2
Aim 3, Optimizing CRC Screening in Patients With Diabetes in Safety-net Primary Care Settings
This mixed methods study evaluates the effectiveness and feasibility of a multi-level (patient, team, organizations) intervention to optimize CRC screening for patients with diabetes in primary care safety-net settings.
- Trial name
- NCT05785780
- Testing
- Targeted CRC Screening Toolkit
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
ColoRectal Cancer Screening
Patient Navigation for Colorectal Cancer Screening for Patients With Mental Illness and/or Substance Use Disorder
The investigators propose to develop, implement, and evaluate a novel Colorectal (CRC) screening patient navigator program for patients with Mental Health (MH) and /or Substance Use Disorder (SUD) receiving care at Massachusetts…
- Trial name
- NCT03244787
- Testing
- patient navigation
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Colorectal Cancer, Type 2 Diabetes
Impact of Colorectal Cancer and Nutrition Education Program Among Minority Patients With Type 2 Diabetes
The goal of this observation study is to deliver an education program designed to increase knowledge of colorectal cancer prevention and nutrition education in minorities with Type 2 diabetes.
- Trial name
- NCT05765214
- Testing
- Intervention Group (IG)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Charles Drew University of Medicine and Science
Healthy Subject, Localized Transitional Cell Cancer of the Renal Pelvis and Ureter
Family Caregiver Palliative Care Intervention in Supporting Caregivers of Patients With Stage II-IV Gastrointestinal, Gynecologic, Urologic and Lung Cancers
This randomized clinical trial studies the Family Caregiver Palliative Care Intervention in supporting caregivers of patients with stage II-IV gastrointestinal, gynecologic, urologic and lung cancers.
- Conditions
- Healthy Subject, Localized Transitional Cell Cancer of the Renal Pelvis and Ureter, Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter, Psychosocial Effects of Cancer and Its Treatment
- Trial name
- NCT01846520
- Testing
- educational intervention, telephone-based intervention, quality-of-life assessment
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Colorectal Cancer Screening, Shared Decision Making
Colorectal Cancer Screening With Improved Shared Decision Making
The purpose of this study is to increase colorectal cancer screening by implementing a community-wide shared decision-making (SDM) intervention, which embeds shared decision making within clinical practice and also uses an…
- Trial name
- CRCS-WISDM (NCT01519999)
- Testing
- Shared Decision Making for Colorectal Cancer Screening
- Where
- United States
- Volunteers
- 206,721 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Non Small Cell Lung Cancer, Esophageal Cancer
Tumor Cell and DNA Detection in the Blood, Urine, and Bone Marrow
Patients with resectable solid primary cancers and even limited number of metastases are potentially curable. However, most patients develop recurrences despite surgery.
- Conditions
- Non Small Cell Lung Cancer, Esophageal Cancer, Gastric Cancer, Pancreatic Cancer
- Trial name
- NCT03551951
- Testing
- Test for circulating tumor cells, DNA alterations
- Where
- United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
HPV-Related Carcinoma, HPV Infection
Determining the Frequency of Occurrence and Defining the Most Appropriate Screening Test for Anal Intraepithelial Neoplasia (AIN) in Patients With Human Papillomavirus (HPV) Related Gynecological Diseases.
The primary aim of the study is to determine the total risk of AIN in group of HPV-RGD survivors and additionally to establish an exact risk for each of HPV-related gynecological precancers/cancers.
- Trial name
- NCT06574087
- Testing
- hrHPV test and cytology
- Where
- Poland
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- PCK Marine Hospital in Gdynia
Hypoxia, Gastric Polyp
The Efficacy and Safety of the COMBO Endoscopy Oropharyngeal Airway in Gastrointestinal Endoscopy Procedure
Hypoxia represents the prevailing adverse occurrence during the sedation of patients undergoing gastrointestinal endoscopy with propofol.
- Conditions
- Hypoxia, Gastric Polyp, Colon Cancer, Esophageal Cancer
- Trial name
- NCT06081647
- Testing
- the COMBO Endoscopy Oropharyngeal Airway, Regular Nasal Cannula
- Where
- 10 sites in China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Acute Myelogenous Leukemia, Ovarian Cancer
Galinpepimut-S in Combination With Pembrolizumab in Patients With Selected Advanced Cancers
To evaluate the safety, tolerability, and anti-tumor activity of galinpepimut-S in combination with pembrolizumab in patients with selected advanced cancers.
- Conditions
- Acute Myelogenous Leukemia, Ovarian Cancer, Colorectal Cancer, Triple-negative Breast Cancer
- Trial name
- NCT03761914
- Testing
- galinpepimut-S, pembrolizumab, Montanide
- Where
- 12 sites in United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Sellas Life Sciences Group
Prevention, LARS - Low Anterior Resection Syndrome
Effectiveness of Pelvic Floor Exercise to Prevent LARS (Low Anterior Resection Syndrome)
The main aim of this randomized study will be to determine the effectiveness of pelvic floor exercises on the incidence or severity of LAR syndrome in patients after mini-invasive rectal resection.
- Conditions
- Prevention, LARS - Low Anterior Resection Syndrome, Pelvic Floor Disorders, Rectal Cancer
- Trial name
- CH1 (NCT06519006)
- Testing
- Pelvic floor exercise
- Where
- Slovakia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- F. D. Roosevelt University Hospital
Colon Cancer, Rectum Cancer
Efficacy of Colonoscopy, Colon Capsule and Fecal Immunological Test for Colorectal Cancer Screening
Efficacy of colonoscopy, colon capsule and fecal immunological test for colorectal cancer screening, in first degree relatives of patients with colorectal neoplasia: a prospective randomized study.
- Trial name
- FAMCAP (NCT02738359)
- Testing
- optical colonoscopy, colon capsule endoscopy, fecal immunological test (FIT)
- Where
- 17 sites in France
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Hôpital Edouard Herriot
Cancer
Laboratory Assay in Determining Cancer Resistance in Patients With Metastatic Cancer and in Healthy Participants
RATIONALE: Studying samples of blood and tissue in the laboratory from patients with cancer and from healthy participants may help doctors learn more about cancer.
- Trial name
- NCT00899496
- Testing
- immunological diagnostic method, physiologic testing
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Diet, Healthy, Colorectal Cancer
Introducing a Plant-Based Diet for Patients With Colorectal Diseases
Dietary patterns are a potentially modifiable risk factor for colon cancer recurrence, flares in inflammatory bowel diseases, and for chronic diseases. Nutritional counseling is rarely brought up during medical appointment.
- Trial name
- NCT05526846
- Testing
- Plant-based diet education
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Stanford University
Colorectal Cancer
Correlation Between Blood Group ,Rh and Obesity With Colorectal Carcinoma
Aim of study: is there possibility of relationship between ABO blood group, Rh \& obesity with CRC, that is what we tried to show in this study .
- Trial name
- NCT05520385
- Testing
- blood group and Rh
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Al-Kindy Teaching Hospital
Colorectal Cancer, Colon Polyps
Prevalence and Topography of Adenomas in 40-49 Year Old Patients With a Family History of Colon Cancer
Conflicting guideline recommendations for screening colonoscopy result due to scant data upon which to develop appropriate recommendations.
- Conditions
- Colorectal Cancer, Colon Polyps, Adenomatous Polyp of Colon
- Trial name
- NCT02289053
- Where
- 6 sites in United States
- Volunteers
- 1,623 people, healthy volunteers welcome
- Sponsor
- University of Michigan