Clinical trials: Patients After Cardiac Surgery
Coronary Artery Disease
Effect of Clopidogrel (Plavix) on Postoperative Bleeding in Patients Undergoing Coronary Artery Bypass Surgery.
Running title: Effect of Clopidogrel on Postoperative Bleeding in Patients undergoing Coronary Artery Bypass Surgery Title: Clopidogrel and bleeding in patients undergoing coronary artery bypass grafting.
- Trial name
- NCT00724880
- Testing
- Clopidogrel
- Volunteers
- 135 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Post Cardiac Surgery
Evaluation of EarlySense Home Care Tele-monitoring Device -For Early Detection of Deterioration For Cardiac Patients at Home
The aim of this study is to evaluate the relevance of the information as provided by the EarlySense Home care Tele-monitoring system can provide relevant flagging information for clinicians to identify the patients at higher risk…
- Trial name
- NCT02659982
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- EarlySense Ltd.
Overall Survival
Intraoperative Dexmedetomidine and Long-term Outcomes in Elderly After Major Surgery
This is a 3-year follow-up of patients enrolled in a previous randomized controlled trial which showed that intraoperative dexmedetomidine reduced delirium in elderly patients after major non-cardiac surgery.
- Trial name
- NCT04111926
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 619 people
- Sponsor
- Peking University First Hospital
Insulin Resistance, Diabetes Mellitus Type 2
Insulin Sensitivity, Irisin and Adipokines as Outcome Parameters in Patients Undergoing Cardiac Surgery
BACKGROUND: Surgical injury and inflammation provoke a stereotypical stress response. Insulin resistance plays an intriguing role in these metabolic alterations and depends on the intensity of injury.
- Conditions
- Insulin Resistance, Diabetes Mellitus Type 2, Other Functional Disturbances Following Cardiac Surgery
- Trial name
- NCT02258698
- Testing
- Cardiac surgery
- Where
- Switzerland
- Volunteers
- 348 people
- Sponsor
- University Hospital, Basel, Switzerland
Cardiovascular Diseases
Effects of Muscle Trainins Inspiratory Linked to Cardiac Rehabilitation Post-operative of CABG Surgery
Heart surgery procedures are still widely used worldwide for the treatment of patients with heart problems, and rates of complications in the postoperative period related to them remain high.
- Trial name
- NCT02742350
- Testing
- IMT - POWERbreathe Plus Light Resistance®, SP, BR
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Hot Climate, Bleeding Tendency
Hot Climate on Bleeding Tendency After Cardiac Surgery in Egyptian Patients
This work aimed to assess the effect of regional climatic differences on postoperative bleeding in Egyptian patients undergoing cardiac surgery with cardiopulmonary bypass, by comparing outcomes between patients from hot climate…
- Conditions
- Hot Climate, Bleeding Tendency, Cardiac Surgery, Egyptian Patients
- Trial name
- NCT07510022
- Testing
- Open heart surgery
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Al-Azhar University
Acute Renal Failure
Fenoldopam and Ketanserin for Acute Kidney Failure Prevention After Cardiac Surgery
The purpose of the study is to compare the effect of fenoldopam and ketanserin on kidney function preservation in patients at high risk for renal failure after cardiac surgery.
- Trial name
- NCT00557219
- Testing
- fenoldopam (Corlopam), ketanserin (Sufrexal)
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Gdansk
Vasoplegia Syndrome
Effects of Vitamin C on Shock Duration and Microcirculation in Patients With Vasoplegia Syndrome After Cardiac Surgery
This pilot study intends to observe the effect of intravenous vitamin C on the prognosis and sublingual microcirculation in patients with vasoplegia syndrome after cardiac surgery through a prospective randomized controlled study…
- Trial name
- NCT06723626
- Testing
- Vit C, Standard Preparation
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Southeast University, China
Cardiac Disease, Critical Illness
In-Bed Cycling in ICU Patients Post Cardiac Surgery
The purpose of this study is to determine if in-bed cycling is safe and feasible in critically-ill patients after open heart surgery.
- Conditions
- Cardiac Disease, Critical Illness, Critical Illness Polyneuropathy, Critical Illness Myopathy
- Trial name
- CardiO Cycle (NCT02976415)
- Testing
- In-Bed Cycling
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- Hamilton Health Sciences Corporation
Heart Failure With Reduced Ejection Fraction
Respiratory Sinus Arrhythmia (RSA) Pacing Post-CABG Surgery in Patients With HFrEF
The goal of this clinical trial is to test a new type of pacemaker in heart failure patients following a heart bypass operation.
- Trial name
- RSA-PACE (NCT06359938)
- Testing
- Atrial pacing with respiratory sinus arrhythmia (RSA) variability, Monotonic right atrial overdrive pacing
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Ceryx Medical Ltd
Coronary Artery Bypass Graft Surgery(CABG)
Effects of Balance Training on Functional Capacity of Patients After Coronary Artery Bypass Grafting Surgery
Background:There are still many gaps in research concerning the effect of balance training on functional capacity of patient after coronary artery bypass graft.
- Trial name
- NCT06490458
- Testing
- Balance Training
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Cardiac Surgery, Aortocoronary Bypass
Remote Ischemic Preconditioning After Cardiac Surgery
Acute kidney injury (AKI) is a well-recognized complication after cardiac surgery with cardiopulmonary bypass (CPB). The aim of this study is to reduce the incidence of AKI by implementing remote ischemic preconditioning and to…
- Trial name
- RIPCRenal (NCT02997748)
- Testing
- Remote ischemic preconditioning (RIPC)
- Where
- Germany
- Volunteers
- 180 people
- Sponsor
- University Hospital Muenster
PCI Patients, DAPT(Dual Antiplatelet Therapy)
Comparison of Cardiovascular Risks Between Hip Fracture Surgery With Continued DAPT（Dual Antiplatelet Therapy ） Within 6 Weeks vs After 6 Weeks Post-PCI（Percutaneous Coronary Intervention）: A Prospective Observational Cohort Study
Percutaneous coronary intervention (PCI) is commonly used to treat stable ischemic heart disease. Among patients, 7.5% require surgical treatment, and up to 20% may need noncardiac surgery (NCS) within two years.
- Conditions
- PCI Patients, DAPT(Dual Antiplatelet Therapy), Hip Fracture Surgeries
- Trial name
- NCT07024446
- Testing
- The time interval between PCI and NCS
- Volunteers
- 50 people
- Sponsor
- Fujian Medical University Union Hospital
Blood Pressure, Perioperative Hypotension
Impact of Continuous Non-invasive Blood Pressure Monitoring on Hypotension in Patients Having Non-cardiac Surgery
This is a randomized trial (1) investigating whether continuous non-invasive finger-cuff blood pressure monitoring reduces the area under a mean arterial pressure (MAP) of 65 mmHg within the first 15 minutes of anesthetic…
- Trial name
- NCT04736862
- Testing
- Continuous non-invasive blood pressure monitoring, Intermittent non-invasive blood pressure monitoring
- Where
- Germany
- Volunteers
- 242 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Cardiac Disease
Early Mobilisation of Post Cardiac Surgery in Geriatrics.
Heart and blood vessel problems together referred to as cardiovascular diseases (CVD) include congenital heart disease, cerebrovascular illness, and coronary heart disease.
- Trial name
- NCT06360146
- Testing
- Early mobilisation
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ahi Evran University Education and Research Hospital
Cardiac Surgery, Thoracic Surgery
Heart Lung Machine Registry
The HeaLMe post-market clinical follow-up registry is undertaken to evaluate the safety and performance of the index devices Heart Lung Machine HL 40 and Temperature Probes TPO-D-HLM L1.8 Adult / Pediatric in patients undergoing…
- Conditions
- Cardiac Surgery, Thoracic Surgery, Vascular Surgery, Cardiopulmonary Bypass
- Trial name
- HeaLMe (NCT06159517)
- Where
- 3 sites in Italy, Spain
- Volunteers
- 184 people
- Sponsor
- Maquet Cardiopulmonary GmbH
Arrythmia
Effect of Sedative Agent on Reducing the Frequency of Arrhythmia in the Patients After Cardiac Surgery
Arrhythmias early in the recovery period after cardio thoracic surgery are common they develop in 11 to 40 percent of patients after coronary-artery bypass grafting.
- Trial name
- NCT05450497
- Testing
- Propofol, Dexmedetomidine, Dexmedetomidine and propofol
- Where
- Ukraine
- Volunteers
- 356 people
- Sponsor
- Anesthesia Research Group UA
Delirium
Delirium and EuroSCORE II in Cardiac Surgery
The goal of this observational study is to find out the association between EuroSCORE II of Delirium in patients undergoing cardiac surgery.
- Trial name
- NCT05218720
- Testing
- EuroSCORE II risk score and CAM-ICU (The Confusion Assessment Method for the Intensive Care Unit)
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Aga Khan University
Cardiac Surgery, Coronary Artery Bypass Grafting
Oscillating Positive Expiratory Pressure (OPEP) Therapy in High Risk Patients Following Cardiac Surgery
Respiratory dysfunction following cardiac surgery is well documented and due in part to the location of the incision and nature of the surgery.
- Conditions
- Cardiac Surgery, Coronary Artery Bypass Grafting, Chronic Obstructive Pulmonary Disease (COPD), Older Adults
- Trial name
- NCT02732574
- Testing
- Oscilatory Positive Expiratory Pressure (OPEP) device
- Where
- Canada
- Volunteers
- 162 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Peak Expiratory Flow Rate, Coronary Artery Bypass Graft Surgery
Additional Effects of Flutter With Conventional Chest Physiotherapy on Peak Expiratory Flow Rate and Chest Expansion in Post CABG Patients With COPD
Flutter therapy is an oscillating positive expiratory pressure (OPEP) technique that combines positive expiratory pressure with airway oscillations to facilitate mobilization and clearance of respiratory secretions.
- Conditions
- Peak Expiratory Flow Rate, Coronary Artery Bypass Graft Surgery, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT07875049
- Testing
- Conventional Chest Physiotherapy, Flutter device with conventional chest physiotherapy
- Where
- Pakistan
- Volunteers
- 84 people
- Sponsor
- Foundation University Islamabad