Clinical trials: Patients Undergoing General Anesthesia
Breast Cancer
Effect of Perioperative Intravenous Lidocaine Infusion and Magnesium Infusion on the Functional Recovery After General Anesthesia in the Patients Undergoing Breast Mastectomy
Postsurgical pain is a relevant side effect following surgery which increases the risk of various complications and delays postoperative patient recovery.
- Trial name
- NCT02185859
- Testing
- Lidocaine, Magnesium Sulfate, Saline
- Where
- South Korea
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Anesthesia, General
A Study to Assess Indices of SNAP vs VISTA on Surgical Patients Undergoing General Anesthesia
Establish the range of index values for the SNAP II corresponding to each anesthetic state studied.
- Trial name
- Precision GA (NCT00829803)
- Testing
- SNAP monitor; Bispectral Index Monitor (BIS Monitor)
- Where
- 4 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Stryker Instruments
Intubation, Endotracheal
Ambu® Laryngeal Mask as an Intubation Conduit
The purpose of this study is to determine if the Ambu Laryngeal Mask can be used as an intubation conduit for endotracheal intubation.
- Trial name
- NCT00272194
- Testing
- Ambu Laryngeal Mask, Aintree Exchange Catheter, Laryngeal Mask Airway
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Anesthesia, Anesthesia; Adverse Effect
Dexamethasone vs Bicarbonate to Intracuff Lignocaine 2% in General Anaesthesia
This study is designed to evaluate and compare the effect on hemodynamics, extubation response and patients satisfaction score in patients with ETT cuff filled with either mixture of lignocaine with sodium bicarbonate or with a…
- Conditions
- Anesthesia, Anesthesia; Adverse Effect, Anesthesia Intubation Complication
- Trial name
- NCT03833947
- Testing
- lignocaine+bicarbonate, lignocaine+dexamethasone
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aligarh Muslim University
Cardiovascular Surgery, Perioperative Neurocognitive Disorders
Exploring the Predictive Value of Electroencephalography Features in Perioperative Neurocognitive Disorders Following Cardiovascular Surgery
To explore the predictive value of Electroencephalography features in Perioperative Neurocognitive Disorders in patients undergoing cardiovascular surgery under general anesthesia
- Trial name
- NCT06692309
- Testing
- cardiovascular surgery
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beijing Chao Yang Hospital
Central Venous Catheters
The Success Rate of Catheter Insertion by the Presence of Obturator During Peripherally Inserted Central Venous Catheter
In pediatric patients under the age of 18 who undergo surgery under general anesthesia, when inserting peripherally inserted central venous catheterization, the group that inserts the catheter with the obturator and the group…
- Trial name
- NCT04393844
- Testing
- turbo-ject PICC set
- Where
- South Korea
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Stress
Intermediate Cervical Plexus Block on Stress Response
The aim of the present study is to investigate the effect of Bilateral Ultrasound-Guided intermediate cervical plexus Block combined with general anesthesia on the stress and inflammatory response in patients undergoing anterior…
- Trial name
- NCT06064214
- Testing
- u/s guided intermediate cervical plexus block
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cairo University
Post Induction Hypotension
Effects of Esketamine and Bilateral Lower Limb Elevation on Hemodynamic Stability During Induction of General Anesthesia in Elderly Patients Undergoing Thoracic Surgery
Video-assisted thoracoscopic surgery (VATS) is widely used in thoracic surgery due to small incisions, low stress response, and high patient tolerance.
- Trial name
- NCT07374458
- Testing
- Esketamine, Bilateral Lower Limb Elevation
- Volunteers
- 292 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Oropharyngeal Leak Pressure, Supraglottic Airway
A Randomised Controlled Trial to Compare Two Supraglottic Airway Devices (Ambu AuraGain vs Air Q-3) in Terms of Performance Characteristics.
A supraglottic airway device (SAD) functions as a temporary device to maintain the patency of airway during the administration of anaesthesia.
- Conditions
- Oropharyngeal Leak Pressure, Supraglottic Airway, Elective Surgery, General Anaesthesia
- Trial name
- NCT06914453
- Testing
- Air Q-3 Supraglottic Airway Device, Ambu AuraGain Supraglottic Airway Device
- Where
- Malaysia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Postoperative Pain
Effect of Noise Isolation on the Incidence of Moderate to Severe Postoperative Pain
To investigate the effect of noise isolation during general anesthesia on the incidence of moderate to severe postoperative pain in patients undergoing major abdominal surgery.
- Trial name
- NCT06316440
- Testing
- Wear noise-cancelling earphones
- Where
- China
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Postoperative Pain, Postoperative Nausea and Vomiting
Effectiveness of Low-Dose Ketamine and Intravenous Lidocaine Versus Fentanyl for Postoperative Pain
Background: Rational approaches to perioperative patient management have been used to meet intraoperative analgesic needs and avoid opioid-related adverse effects.
- Trial name
- Vs(versus) (NCT07213687)
- Testing
- Low dose intravenous ketamine
- Where
- Ethiopia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Dilla University
Music Therapy, Music Therapy for Pain and Sedation
Effect of Music Therapy on the Quality of Recovery
Background: The use of music in operations is increasing due to its painless, safe, inexpensive, and the potential to improve patient outcomes.
- Conditions
- Music Therapy, Music Therapy for Pain and Sedation, Postoperative Period, Perioperative Period
- Trial name
- MTonR (NCT06874972)
- Testing
- Music played
- Where
- Bhutan
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Bhutan
Throat, Sore
Pilot Study of Throat Packs Soaked in Gengigel Spray in Patients Undergoing Elective Surgery
Throat packs are commonly used in many surgical procedures involving the oral cavity and pharynx, primarily to prevent blood, saliva, and other debris from entering the lower respiratory tract, thereby maintaining a clear airway…
- Trial name
- NCT06947161
- Testing
- Gengigel
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Patients Undergoing Elective General Anesthesia
Laryngeal Mask Supreme™ Versus the I-gel™
We evaluate two new developed airway devices, which provide patent airway during general anesthesia. In 60 patients undergoing elective general anesthesia, we will simulate a difficult airway by using an extrication device…
- Trial name
- NCT00653237
- Testing
- I-gel and LMA Supreme: supraglottic airway devices
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Early Recovery in Elderly Patients, Cognitive Function
Effects of Sevoflurane vs Desflurane on Early Recovery and Cognitive Function in Elderly Patients Undergoing Scheduled Non-Cardiac Surgery
The goal of this clinical study is to compare the effects of desflurane versus sevoflurane on early postoperative recovery and cognitive function in elderly patients (aged 60 years and older, ASA I-III) undergoing elective…
- Trial name
- NCT07289945
- Testing
- Sevoflurane, Desflurane
- Where
- Tunisia
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Hopital Charles Nicolle
Laryngoscopic Stress Response, Video Laryngoscopy
Effect of Video Laryngoscopy Versus Conventional Laryngoscopy Upon Hemodynamics
In general anestheisa airway is secured by passing a tube down the widpipe. This helps the patient to breath via ventilator during anesthesia.
- Conditions
- Laryngoscopic Stress Response, Video Laryngoscopy, Conventional Laryngoscopy
- Trial name
- NCT07300878
- Testing
- C MAC hyperangulated video laryngoscopy, Conventional macintosh laryngoscopy
- Where
- Pakistan
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Urologic Diseases
10 Minutes Prewarming and Warmed Intravenous Fluid on Core Temperature
Hypothermia occurs frequently during general anesthesia. This study is to evaluate the efficacy of 10 minutes of prewarming and warmed fluid during urologic surgery.
- Trial name
- NCT04991272
- Testing
- prewarming and warmed fluid infusion
- Where
- South Korea
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Inje University
Mechanical Ventilation, Lung Protective Ventilation
Driving Pressure Guided Mechanical Ventilation Versus Lung Protective Ventilation Among Patients Undergoing Elective Surgeries
Patient undergoing surgeries in general anesthesia require support of their breathing by ventilator. Different strategies can be used to manage breathing of the patient.
- Conditions
- Mechanical Ventilation, Lung Protective Ventilation, Driving Pressure
- Trial name
- NCT07092943
- Testing
- Lung protective ventilation, Driving pressure guided ventilation
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Rawalpindi Medical College
Double Level Lumbar Spondylolisthesis (L3-L5), Posterior Lumbar Interbody Fusion (PLIF)
Effect of Addition of Dexmedetomidine During Ultrasound Guided Bilateral Single Shot Erector Spinae Plane Block in Patients Undergoing Posterior Lumbar Interbody Fusion Under General Anesthesia
Posterior lumbar interbody fusion (PLIF) is the management of choice in double level lumbar (L) spondylolisthesis (L3-L5) after ineffective conservative treatment.
- Conditions
- Double Level Lumbar Spondylolisthesis (L3-L5), Posterior Lumbar Interbody Fusion (PLIF), Lumbar Fixation Surgery
- Trial name
- NCT03746418
- Testing
- Ultrasound Guided Bilateral single shot Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tanta University
Sore-throat
Incidence of Postoperative Sore-throat Incidence
Postoperative sore throat is a distressing but frequent symptom presented by the patients on the floor upon awakening from General Anesthesia, where endotracheal intubation is part of the Anesthetic protocol.
- Trial name
- InciPost (NCT05354154)
- Testing
- endotracheal intubation
- Where
- Pakistan
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Rehman Medical Institute - RMI