Clinical trials: Patients Undergoing Laparoscopic Surgery
Colorectal Cancer, Circulating Tumor Cell
Influence of Opioid Analgesia on Circulating Tumor Cells in Laparoscopic Colorectal Cancer Surgery
To compare the effects of three types of perioperative analgesia on the number of circulating tumor cells following radical colorectal cancer surgery.
- Trial name
- POACC-2 (NCT03700541)
- Testing
- Morphine, Piritramid
- Where
- 3 sites in Czechia
- Volunteers
- 71 people
- Sponsor
- The Institute of Molecular and Translational Medicine, Czech Republic
Laparoscopic Surgery
Effects of Continuous Dexmedetomidine Infusion on Systemic Microvascular Function in Laparoscopic Cholecystecthomy
The microcirculation represents the primary site of exchange of oxygen and nutrients for tissues, and the preservation of microcirculatory perfusion is essential for the maintenance of organ function.
- Trial name
- NCT04946396
- Testing
- dexmedetomidine intravenous infusion, 0.9%sodium chloride
- Where
- Brazil
- Volunteers
- 64 people
- Sponsor
- National Institute of Cardiology, Laranjeiras, Brazil
Gallstone Disease, Ultrasonic Diagnosis
Transabdominal and Laparoscopic Ultrasound in a Bariatric Setting
Every year, many patients undergo weight-loss (bariatric) surgery. While this surgery leads to significant and intended weight loss, it also increases the risk of developing gallstones or other gallbladder problems.
- Conditions
- Gallstone Disease, Ultrasonic Diagnosis, Bariatric Patients Undergoing Bariatric Surgery
- Trial name
- NCT07453186
- Testing
- Diagnostic procedures
- Where
- Denmark
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Renal Cancer, Surgery-Complications
Assessment of Complications in Patients Who Underwent LPN According to the CCI
This study aims to compare the strength of the classical Clavien-Dindo classification system (CDC), which is a Likert scale analysis versus the comprehensive complication index (CCI), a new quantitative evaluation system, in…
- Trial name
- NCT05823545
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Samsun Liv Hospital
Morbid Obesity Requiring Bariatric Surgery, Postoperative Pain
Effect of Lidocaine-Dexmedetomidine on Pain, Inflammation, and Oxidative Stress After Bariatric Surgery.
The goal of this randomized clinical trial is to find out whether giving an intravenous lidocaine + dexmedetomidine combination (LIDEX) during laparoscopic bariatric surgery can lower post-operative pain, inflammation, and…
- Conditions
- Morbid Obesity Requiring Bariatric Surgery, Postoperative Pain, Postoperative Pain Management, Postoperative Analgesia
- Trial name
- NCT07073846
- Testing
- Intravenous Lidocaine infusion + Standard Anesthesia, Intravenous Dexmedetomidine infusion + Standard Anesthesia, Lidocaine + Dexmedetomidine Combination (LIDEX) + Standard Anesthesia
- Where
- 2 sites in Mexico
- Volunteers
- 104 people
- Sponsor
- Instituto Mexicano del Seguro Social
Laparoscopic Nephrectomy, Enhanced Recovery After Surgery
Patients Undergoing Laparoscopic Nephrectomy Walk Out From Operating Room After Surgery
Early mobilization is considered as an important strategy to enhance postoperative recovery. However, direct association between very early mobilization and improved recovery needs randomized control trials to prove.
- Trial name
- WOFOR-N1 (NCT03960697)
- Testing
- walk out from operating room
- Where
- 2 sites in China
- Volunteers
- 182 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Positive-Pressure Respiration/Methods, Esophagus/Physiopathology
Intraoperative PEEP Setting During Laparoscopic Gynecologic Surgery
The creation of pneumoperitoneum during laparoscopic surgery can have significant effects on the respiratory system including decreased respiratory system compliance, decreased vital capacity and functional residual capacity and…
- Conditions
- Positive-Pressure Respiration/Methods, Esophagus/Physiopathology, Pleura/Physiopathology, Gynecologic Surgical Procedures
- Trial name
- NCT03256396
- Testing
- PEEP setting based on esophageal pressure measured
- Where
- Thailand
- Volunteers
- 44 people
- Sponsor
- Mahidol University
Hypothermia Following Anesthesia, Hypothermia
Preoperative Warming Prevents Postoperative Hypothermia in Laparoscopic Gynecologic Surgery. A Randomized Control Trial
This study examined whether 20 minutes of prewarming prior to gynecological laparoscopic surgery prevented inadvertent post-operative hypothermia.
- Conditions
- Hypothermia Following Anesthesia, Hypothermia, Hypothermia, Accidental, Body Temperature Changes
- Trial name
- NCT02518815
- Testing
- 3M Bair Paws Warming System
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- Michael Garron Hospital
Prostate Hypertrophy, Renal Disease
Effect of Deep BLock on Intraoperative Surgical Conditions
Rationale: A deep neuromuscular block is often associated with improved surgical conditions especially in laparoscopic surgery. However, a deep block comes at the expense of a variety of items that may conflict with the use of a…
- Trial name
- BLISS (NCT01631149)
- Testing
- Surgical block (rocuronium; atracurium/mivacurium)
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Leiden University Medical Center
Postoperative Pain After Laparoscopic Liver Resection
Intraoperative Continuous Lidocaine Infusion in Laparoscopic Liver Surgery
The goal of this clinical trial is to learn about effect of intraoperative continuous lidocaine infusion on postoperative pain, gut function and insulin resistance in patients undergoing laparoscopic liver surgery in adults.
- Trial name
- ICLIL (NCT07012889)
- Testing
- lidocaine infusion
- Volunteers
- 94 people
- Sponsor
- Medical University of Warsaw
Postoperative Pain
Effect of Noise Blocking During General Anesthesia on Postoperative Pain
To investigate the effect of noise blocking during general anesthesia on postoperative pain in patients undergoing laparoscopic abdominal surgery.
- Trial name
- NCT05540691
- Testing
- Wear noise-cancelling earphones
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Gynecologic Disease, Cosmesis
Comparison of Cosmesis, Patient Satisfaction and Quality of Life in Patients Undergoing Laparoscopic Surgery
To compare robot assisted versus conventional laparoscopic surgery performed for bening gynecologic disorders regarding cosmesis, patient satisfaction and quality of life
- Conditions
- Gynecologic Disease, Cosmesis, Patient Satisfaction, Quality of Life
- Trial name
- NCT04064216
- Testing
- Laparoscopic surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Pneumoperitoneum, Renal Injury
Evaluation of Renal Perfusion With NIRS in Laparoscopic Surgery
The investigators aimed to show the renal damage caused by increased intra-abdominal pressure in laparoscopic surgeries and to investigate whether its reflection on NIRS would be clinically effective.The main question it aims to…
- Trial name
- NCT06116383
- Testing
- NIRS
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Postoperative Pain, Acute, Postoperative Pain, Chronic
Postoperative Pain in Patients Undergoing Scheduled Laparoscopic Intestinal Resection Surgery
This observational prospective study aims to evaluate the postoperative analgesic effect of a regional anesthesia thechnique (TAP block) in patients undergoing scheduled laparoscopic intestinal resection for intestinal cancer.
- Trial name
- TAP (NCT05222789)
- Testing
- TAP
- Where
- Spain
- Volunteers
- 105 people
- Sponsor
- Hospital Universitario de Gran Canaria Doctor Negrín
Fluid Responsiveness
Pressure Gradient for Venous Return in Predicting Fluid Responsiveness in Patients Undergoing Laparoscopic Surgery
Surgical patients, especially those with insufficient blood volume and hypotension, often need fluid therapy. However, there is still a lack of simple and reliable indicators for judging transfusion responsiveness in some types…
- Trial name
- NCT04030221
- Testing
- fluid infusion
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Shoulder Pain
Dexmedetomidine as an Adjuvant to Bupivacaine in Ultrasound-guided Pericapsular Nerve Group Block( PENG)
Patients are greatly concerned about pain that occurs shortly after shoulder surgeries. Most patients experience significant pain after shoulder surgery, with almost half reporting severe pain immediately after.
- Trial name
- NCT07626346
- Testing
- nerve block
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Acute Kidney Injury, Obesity
Does the Presence of Preoperative Proteinuria Predict Postoperative Acute Kidney Injury in Obese Patients Undergoing Elective Laparoscopic Surgery?
Acute kidney injury (AKI) is a common, but significant complication after elective surgery which is associated with an increased risk of mortality, major adverse cardiac events, prolonged length of hospital stay, and increased…
- Conditions
- Acute Kidney Injury, Obesity, Proteinuria
- Trial name
- NCT02798042
- Testing
- Urine Sample
- Where
- United States
- Volunteers
- 1,434 people
- Sponsor
- NYU Langone Health
Obesity, Bariatric Surgery
Modified Thoracoabdominal Nerve Plane Block In Laparoscopic Sleeve Gastrectomy
Ultrasound-guided Modified Thoracoabdominal Nerve Plane Block (M-TAPA) is performed into the costochondral aspect at the 9th-10th costal level by injecting local anesthetics deep into the chondrium.
- Conditions
- Obesity, Bariatric Surgery, Laparoscopic Sleeve Gastrectomy, Acute Post Operative Pain
- Trial name
- NCT06515691
- Testing
- M-TAPA block, Postoperative pain management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Medipol University Hospital
Flurbiprofen Axetil, Preemptive Analgesia
Effect of Preemptive Analgesia With Flurbiprofen Axetil on Perioperative Sleep Quality and Postoperative Pain in Patients Undergoing Laparoscopic Gynecological Surgery.
In humans and animals, circadian rhythm sleep cycle is an important function to maintain and regulate basic physiological homeostasis, such as cognitive function, glucose metabolism, memory consolidation, immune function and…
- Conditions
- Flurbiprofen Axetil, Preemptive Analgesia, Postoperative Pain, Perioperative Sleep Quality
- Trial name
- NCT04611763
- Testing
- Flurbiprofen axetil preoperatively, Flurbiprofen axetil postoperatively
- Where
- China
- Volunteers
- 112 people
- Sponsor
- Beijing Friendship Hospital
Robot-Assisted Laparoscopic Radical Prostatectomy
The Impacts of Surgical Visibility Through Deep Neuromuscular Blockade on Intraocular Pressure in Patients Undergoing Robot-Assisted Laparoscopic Radical Prostatectomy
Intraocular pressure is significantly increase during robot-assisted laparoscopic radical prostatectomy which is performed in a steep trendelenburg position at prolonged times of pneumoperitoneum.
- Trial name
- NCT02109133
- Testing
- deep neuromuscular blockade, moderate neuromuscular blockade, Rocuronium
- Where
- South Korea
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Yonsei University