Clinical trials: Patients Undergoing Laparoscopic Surgery
Postoperative Pain Management
Ultrasound-Guided Versus Laparoscopy-Guided Transversus Abdominis Plane Block for Postoperative Analgesia
This prospective, randomized, double-blind study aimed to compare the effects of ultrasound-guided versus laparoscopy-guided transversus abdominis plane(TAP) block on postoperative analgesia in patients undergoing laparoscopic…
- Trial name
- US-LTAP (NCT07352189)
- Testing
- Ultrasound-guided Transversus Abdominis Plane (US-TAP) Block, Laparoscopy-guided Transversus Abdominis Plane (LS-TAP) Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Neuromuscular Blockade
Rocuronium + Sugammadex vs. Succinylcholine + Cisatracurium + Neostigmine/Atropine in Obese Participants (MK-8616-104)
The primary objective of this trial is to compare the preference between two strategies of neuromuscular blocking (NMB) / reversal in adult obese patients undergoing laparoscopic abdominal surgery: Rocuronium + Sugammadex versus…
- Trial name
- BENN (NCT02410590)
- Testing
- Rocuronium, Sugammadex, Cisatracurium
- Sponsor
- Merck Sharp & Dohme LLC
Neurocognitive Disorder, Dexmedetomidine Infusion
Effects of Dexmedetomidine on Postoperative Neurocognitive Disorder
This prospective study involves assessing neurocognitive function in patients undergoing laparotomic gastrointestinal surgery. Mini Mental state Assessment test and Mini-Cog tests will be conducted at multiple intervals…
- Conditions
- Neurocognitive Disorder, Dexmedetomidine Infusion, Postoperative Cognitive Dysfunction, Postoperative Cognitive Dysfunction(POCD)
- Trial name
- NCT06689137
- Testing
- mini mental state assessment test, mini-cog test
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Haseki Training and Research Hospital
Rescue Analgesia
Comparison of Rescue Analgesia Requirement in Patients Undergoing Laparoscopic Cholecystectomy After Transversus Abdominal Plane (tap) Block Vs Local Anesthetic Wound Infiltration At the End of Surgery
patients undergoing laparoscopic cholecystectomy will be diveided into 2 groups A \& B . Group A will receive local anesthetic wound infiltration and group B will receive Transversus abdominal plane block as a post operative…
- Trial name
- TAP (NCT06803966)
- Testing
- Post Operative Analgesia
- Where
- Pakistan
- Volunteers
- 74 people
- Sponsor
- Fazaia Ruth Pfau Medical College
Postoperative Pulmonary Complications, Risk Factors
Incidence and Risk Factors of PPCs in Elderly Patients Undergoing Robot Assisted Laparoscopic Pelvic Surgery
Postoperative pulmonary complications are important factors affecting the prognosis of patients undergoing surgery. Studies have shown that patients undergoing abdominal or pelvic surgery, emergency surgery, or prolonged surgery…
- Trial name
- NCT05519657
- Volunteers
- 154 people
- Sponsor
- Tongji Hospital
Laparoscopic Cholecystectomy
Low-Dose Ketamine Infusion for Post-Operative Pain in Patients Undergoing Laparoscopic Cholecyctectomy
Following surgery, acute pain is a typical issue with a variety of implications. Surgeons, anesthesia specialists, and patients all desire effective pain management with the fewest possible adverse effects.
- Trial name
- NCT06966596
- Testing
- Ketamine only
- Where
- Pakistan
- Volunteers
- 116 people
- Sponsor
- Fazaia Ruth Pfau Medical College
Other Surgical Procedures
Effects of PEEP on Optic Nerve Sheath Diameter During Robot-Assisted Laparoscopic Prostatectomy
The investigators aim to investigate the effects of positive end-expiratory pressure ventilation on intracranial pressure assessed by sonographic optic nerve sheath diameter in patients undergoing robot-assisted laparoscopic…
- Trial name
- NCT02516566
- Testing
- PEEP
- Volunteers
- 38 people
- Sponsor
- Asan Medical Center
Gynecologic Disease
Magnesium Sulfate; Postoperative Nausea and Vomiting; Laparoscopic Surgery
Postoperative nausea and vomiting (PONV) is commonly accompanied in patients undergoing surgery under general anesthesia. The patients undergoing laparoscopic gynecologic surgery have multiple risk factors for developing PONV…
- Trial name
- NCT03541915
- Testing
- Mg (magnesium sulfate), Control (saline)
- Volunteers
- 90 people
- Sponsor
- Gangnam Severance Hospital
Laparoscopic Cholecystectomy Surgery
Beneficial Effects of Low-Dose Intravenous Dexmedetomidine Premedication in Patient Undergoing Laparoscopic Cholecystectomy Under General Anesthesia
Laparoscopic cholecystectomy (LC) is considered the standard treatment for gallbladder disease.1 Compared to open cholecystectomy, LC is the preferred treatment approach because it is associated with less surgical trauma, shorter…
- Trial name
- NCT06838650
- Testing
- Dexmedetomidine, Saline
- Volunteers
- 100 people
- Sponsor
- Assiut University
Pain, Surgery
Pre Operative Transversus Abdominis Plane Block Laparoscopic Gynecological Surgery
The use of pre-operative transversus abdominis plane block will reduce pain after outpatient laparoscopic gynecological surgery and improve quality of recovery.
- Trial name
- NCT01075074
- Testing
- Transversus abdominis plane block
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Northwestern University
Laparoscopic Cholecystectomy
Effect of Liberal and Restrictive IV Fluids on Recovery After Gallbladder Surgery
The goal of this clinical trial is to learn whether giving less intravenous (IV) fluid (restrictive administration) after surgery is as effective as giving more IV fluid (liberal administration) in maintaining body stability…
- Trial name
- NCT07488078
- Testing
- Lactated Ringer 500ml, Lactated Ringer 1000ml
- Where
- Pakistan
- Volunteers
- 380 people
- Sponsor
- King Edward Medical University
Postoperative Pain
Clinical Meaning of Visual Analog Scales(VAS) for Teenage Pediatric Patients Undergoing Laparoscopic Surgical Procedures
The purpose of this study is to find a more accurate postoperative pain assessment for teenager patients. This is important because a patient should not have a very strong pain medication such as morphine if the pain is just mild.
- Trial name
- NCT01755065
- Where
- United States
- Volunteers
- 206 people
- Sponsor
- University of Pittsburgh
Laparoscopic Gynecological Surgery
EEG and ANI Guided Anesthesia and Quality of Recovery
This study aims to assess whether electroencephalogram (EEG) and nociception level-guided anesthesia can improve quality of recovery after laparoscopic gynecological surgery compared with standard care.
- Trial name
- NCT05936671
- Testing
- EEG-and-ANI-guided anesthesia, standard anesthesia, Sevoflurane and remifentanil
- Where
- 2 sites in South Korea
- Volunteers
- 126 people
- Sponsor
- Gangnam Severance Hospital
Pain
Study to Evaluate the Efficacy of Pre-operative Administration of Etoricoxib 120 mg, Etoricoxib 120 mg and Paracetamol 1 g Combination or Placebo in the Treatment of Postoperative Pain in Patients Undergoing Gynaecologic Laparoscopic Surgery
Primary Hypothesis: 1. The analgesic effect of etoricoxib 120 mg administered 1 hour preoperatively is greater than that of placebo in the treatment of postoperative pain.
- Trial name
- NCT00763685
- Testing
- etoricoxib
- Where
- Estonia
- Volunteers
- 40 people
- Sponsor
- East Tallinn Central Hospital
Postoperative Pain, Laparoscopic Cholecystectomy Surgery
Impact of Video-Based Patient Education on Physician Trust, Pain, and Anxiety in Laparoscopic Cholecystectomy
This prospective, randomized, single-center, single-blind study aims to evaluate the effects of video-based preoperative education on physician trust, postoperative pain, anxiety, and opioid consumption in patients undergoing…
- Conditions
- Postoperative Pain, Laparoscopic Cholecystectomy Surgery, Preoperative Anxiety, Trust in Healthcare System
- Trial name
- VITAP (NCT07767344)
- Testing
- Video-Based Preoperative Block Education, Standard Verbal Preoperative Block Education
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Sanliurfa Education and Research Hospital
Postoperative Nausea and Vomiting
PONV Prevention Via Percutaneous Nerve Electrical Stimulation on PC6
This study aims to certify the effectiveness of percutaneous electrical nerve stimulation at Pericardium 6 (PC6) via a wearable equipment during perioperative period on preventing postoperative nausea and vomiting.
- Trial name
- NCT06241547
- Testing
- electrical stimualtion via EmeTerm bracelet, antimetic drugs（ dexamethasone，ondansetron）
- Where
- China
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Suspected Appendicitis
Preoperative Methylprednisolone to Patients Suspected of Appendicitis Undergoing Laparoscopy
To test whether 125 mg preoperative methylprednisolone intravenously can reduce postoperative pain after laparoscopy for suspected appendicitis and to test whether preoperative methylprednisolone can reduce postoperative fatigue…
- Trial name
- NCT02711449
- Testing
- Methylprednisolone, 0.9% Saline
- Where
- 2 sites in Denmark
- Volunteers
- 78 people
- Sponsor
- Jakob Kleif
Acute Lung Injury
The Impact of Automatic Lung Recruitment Postoperative Pulmonary Complications
Study Background and Purpose As society ages, an increasing number of elderly patients undergo surgery. Following surgery, particularly abdominal procedures, patients are susceptible to lung-related issues such as atelectasis…
- Trial name
- lung (NCT07477951)
- Testing
- Automated recruitment maneuver (Auto-RM)
- Where
- China
- Volunteers
- 58 people
- Sponsor
- Yongtao Sun
Obese Patients, Bariatric Surgical Pain
Non-opioid Anesthesia Based on Thoracic Paravertebral Block During Laparoscopic Sleeve Gastrectomy
Regional anesthesia is a technique in which a local anesthetic is injected near a nerve or spinal cord to block sensation, motor stimulation, and pain.
- Conditions
- Obese Patients, Bariatric Surgical Pain, Bariatric Surgery (Sleeve Gastrectomy ), Non-Opioid Pain Management
- Trial name
- NCT07084753
- Testing
- Levobupivacaine, Dexamethasone contained in the solution for thoracic paravertebral block, Adrenaline
- Where
- Croatia
- Volunteers
- 36 people
- Sponsor
- IVO JURISIC
Surgery
ERAS Protocol in Laparoscopic Hysterectomy
ERAS protocol has been shown to improve patient comfort and reduce the length of hospital stay. This study aimed to investigate the impact of implementing ERAS protocols on healthcare costs in patients undergoing a laparoscopic…
- Trial name
- NCT03986450
- Testing
- Enhanced recovery after surge(ERAS) protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital