Clinical trials: Pediatric Pain
Pediatric Disorder
Comparing the Difference in Pain Control in the Pediatric General Surgery Population: to Alternate or Combine Acetaminophen and Ibuprofen?
To examine the difference in pain control in the pediatric general surgery population alternating acetaminophen and Ibuprofen q 3 hours vs giving them simultaneous combination therapy around the clock.
- Trial name
- NCT06505148
- Testing
- Acetaminophen, Ibuprofen
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Baylor Research Institute
Pain Management
The Effect of the Flipped Classroom Model on Pediatric Pain Management Knowledge and Learning Motivation of Nursing Students
The aim of this randomized controlled trial was to evaluate the effect of the flipped classroom model on pediatric pain management knowledge and learning motivation among nursing students.
- Trial name
- FLIPNURSE (NCT07129044)
- Testing
- Flipped Classroom Training on Pediatric Pain Management, Self-Directed Learning on Pediatric Pain Management
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Mustafa Belli
Appendicitis, Hernia
Aromatherapy Versus Acupressure: Impact on Postoperative Pain and Sleep Quality in Pediatric Abdominal Surgery Patients
The study's aim is to examine the effect of using aromatherapy versus acupressure on pain intensity and sleep pattern for children undergoing abdominal surgeries.
- Conditions
- Appendicitis, Hernia, Abdominal Exploration, Splenectomy
- Trial name
- NCT07157501
- Testing
- Accupressure, Aromatherapy inhaler
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Regional Anesthesia Morbidity
Comparison of Femoral Nerve Block Versus Fascia Iliaca Compartment Block for Pain Control in Traumatic Femur Fracture Repair in Pediatric Population
Pediatric orthopedic surgical procedures require a multimodal approach for anesthetic management that maximizes both patient comfort and safety.
- Trial name
- NCT05882201
- Testing
- Fascia Iliaca compartment block group, Femoral nerve block group, General care
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Menoufia University
Pediatric Pain
'My Life is Music' Group Therapy Model - a Feasibility Study for Adolescents With Persistent Pain
The aim of this multi-method feasibility study is to learn if a group therapy model using music can be applied in the treatment of adolescents with persistent pain.
- Trial name
- PedPainMusic (NCT06576219)
- Testing
- Group Music Therapy
- Where
- Finland
- Volunteers
- 24 people
- Sponsor
- Helsinki University Central Hospital
Gastrointestinal Endoscopy, Procedural Anxiety
Virtual Reality as a Nursing Intervention for Anxiety and Pain in Pediatric Endoscopy
This randomized controlled trial aims to evaluate the effectiveness of a virtual reality (VR) intervention in managing anxiety, post-procedural pain, and recovery time among pediatric patients undergoing gastrointestinal (GI)…
- Conditions
- Gastrointestinal Endoscopy, Procedural Anxiety, Pain
- Trial name
- NCT07274111
- Testing
- Virtual Reality Head-Mounted Display
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Mansoura University
Chronic Pain
Clinical Assessment of Pain Processes in Pediatric Patients With Chronic Musculoskeletal Pain
Musculoskeletal (MSK) pain is one of the most common types of pain among children and adolescents. Recurring episodes of MSK pain during childhood does not only impact physical and psychological aspects of daily life but may…
- Trial name
- MSK (NCT04308044)
- Where
- Canada
- Volunteers
- 518 people, healthy volunteers welcome
- Sponsor
- Shriners Hospitals for Children
C23.888.592.612.081
Evaluation of an App Based on Artificial Intelligence for Pain Assessment in Pediatric Department
Accurate assessment of pain in Pediatric Department is challenging. However, recent publications highlight that children do not receive optimal pain management, particularly in Emergency Departments.
- Trial name
- DEF II (NCT05527600)
- Testing
- intensity of acute pain evaluation
- Where
- 2 sites in France
- Volunteers
- 2,500 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Postoperative Pain
Safety and Efficacy of Magnesium Sulphate as an Adjuvant to Levobupivacaine in Ultra-sound Guided Transversus Abdominis Plan Block in Pediatric Abdominal Cancer Surgery
To study the efficacy of magnesium sulphate as adjuvant to levobupivacaine in transversus abdominis plane (TAP) block in patient undergoing abdominal cancer surgery.
- Trial name
- NCT03979599
- Testing
- ultra-sound guided transversus abdominis plan block, magnesium sulphate& levobupivacaine, Levobupivacaine
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- South Egypt Cancer Institute
Sickle Cell Disease
Integrative Training Program for Pediatric Sickle Cell Pain
This research aims to answer the question: does a group training program specifically for teens with chronic sickle cell disease (SCD) pain that teaches skills to strengthen the mind and body help improve everyday functioning and…
- Trial name
- I-STRONG SCD (NCT06691867)
- Testing
- I-STRONG, Enhanced Usual Care (EUC)
- Where
- 4 sites in United States
- Volunteers
- 155 people
- Sponsor
- Emory University
Chronic Postoperative Pain, Pediatric ALL
Chronic Postsurgical Pediatric Pain. Evaluation Risk Factors to Develop Chronic Postsurgical Pain in Children and Adolescents Undergoing Surgery in a First Level Hospital
Chronic postsurgical pain had number of prevalence on 20%. Its derivates from risk factors, but recent research provide new potential risk factors to develop chronic postsurgical pediatric pain.
- Trial name
- NCT04735211
- Testing
- Surgery
- Where
- Spain
- Volunteers
- 260 people
- Sponsor
- Guillermo Ceniza Bordallo
Appendix Rupture, Pain
Virtual Reality for Appendectomy Pain
To determine the impact of VR-Biofeedback and VR-Distraction on pain and medication utilization in children and adolescents undergoing surgery for ruptured appendix.
- Conditions
- Appendix Rupture, Pain, Pain, Postoperative
- Trial name
- NCT04357132
- Testing
- VR-Biofeedback, VR-Distraction
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Pediatric Procedural Sedation
Intranasal Dexmedetomidine vs. Oral Chloral Hydrate for Pediatric Orthopedic Procedural Sedation
This prospective randomized controlled study will compare the effectiveness and safety of intranasal dexmedetomidine with oral chloral hydrate for procedural sedation in children undergoing painful orthopedic manipulation.
- Trial name
- NCT07768566
- Testing
- Dexmedetomidine, Chloral Hydrate
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Seoul National University Childrens Hospital
Nursing Caries, Emergencies
Venopuncture in Pediatric Emergency Department Using Koala's Distraction Method
A randomized clinical trial will be performed. Patients aged 3 and 4 years who attend the pediatric emergency service of the Miguel Servet Hospital in Zaragoza and require venipuncture will be selected.
- Conditions
- Nursing Caries, Emergencies, Venous Puncture
- Trial name
- NCT05453305
- Testing
- Control group: Traditional venipuncture, on the stretcher., Intervention group: DAK method venipuncture, simulating a hug
- Where
- Spain
- Volunteers
- 220 people
- Sponsor
- Instituto de Investigación Sanitaria Aragón
Acute Pain
A Multi-Center Study of the Efficacy, Pharmacokinetics (PK) and Pharmacodynamics (PD) of IV Acetaminophen for the Treatment of Acute Pain in Pediatric Patients
The purpose of this study is to demonstrate the efficacy and safety of Intravenous (IV) acetaminophen plus rescue opioids for the relief of moderate to severe acute pain in neonates and infants (age < 2 years) compared to placebo…
- Trial name
- NCT01635101
- Testing
- IV Acetaminophen, IV Control
- Where
- 22 sites in United States
- Volunteers
- 197 people
- Sponsor
- Mallinckrodt
Local Anesthetic Infiltration, Topical Anesthesia
Topical Cryoanesthesia Versus Benzocaine in Pediatric Dentistry
This clinical study tested and compared two ways (cold-base technique or "cryoanesthesia" and conventional benzocaine gel) to reduce pain from dental injections in children.
- Conditions
- Local Anesthetic Infiltration, Topical Anesthesia, Pain Perception
- Trial name
- No acronym (NCT07351383)
- Testing
- Local Anesthesia (lidocaine hydrochloride)
- Where
- Mexico
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de San Luis Potosí
Pain, Postoperative
Efficacy of Transversus Abdominis Plane Block for Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is associated with considerable postoperative pain and surgeon-administered local anesthetic infiltration is the standard practice for achieving post-operative analgesia.
- Trial name
- NCT02712151
- Testing
- Abdominal Wall Block, Surgical infiltration, Sterile saline
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Procedural Pain Relief, Virtual Reality
AI-Generated Video Distraction Via Virtual Reality for Fear and Pain During Pediatric Circumcision
This randomized controlled trial evaluated the effect of artificial intelligence-generated video distraction delivered via virtual reality on procedural fear and pain in children undergoing circumcision.
- Conditions
- Procedural Pain Relief, Virtual Reality, Fear, Child
- Trial name
- NCT07824427
- Testing
- AI-Generated Video Distraction via Virtual Reality
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Chronic Pain
Ketamine in Chronic Kid's (KiCK) Pain
This study is designed to select the most tolerable dose of oral ketamine for children with chronic pain. Children will be given either placebo or one of three dosages of oral ketamine for 2 weeks.
- Trial name
- KiCK Pain (NCT01755169)
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Medical University of South Carolina
Pain, Chronic, Pain
SPRINT: Signature for Pain Recovery IN Teens
To identify biological and phenotypic prognostic markers of recovery vs. persistence of pain and functional disability in adolescents with chronic musculoskeletal pain.
- Conditions
- Pain, Chronic, Pain, Joint Pain, Musculoskeletal Pain
- Trial name
- SPRINT (NCT04285112)
- Where
- 4 sites in United States, Canada and 1 more
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Stanford University