Clinical trials: Pediatric Population
Encephalitis
Immunogenicity and Safety of the Japanese Encephalitis Vaccine IC51 (IXIARO®, JESPECT®) in a Pediatric Population in Non-endemic Countries
The primary objective is to assess the safety profile of IC51 in a pediatric population from regions where JEV is not endemic
- Trial name
- NCT01047839
- Testing
- IC51
- Where
- 10 sites in United States, Australia and 3 more
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Valneva Austria GmbH
Metabolic Dysfunction Associated Steatotic Liver Disease, Non-Alcoholic Fatty Liver Disease (NAFLD)
Non-Invasive Diagnostic Tests for MASLD in Pediatric Population
This study aims to test the utility of Velacur ultrasound as a non-invasive, rapid, point of care diagnostic tool for detecting the presence and amount of hepatic steatosis in children and adolescents aged 2 - 20 years.
- Trial name
- NCT06218589
- Testing
- Velacur, MRI, Blood sample collection for biomarkers
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Emory University
Phalanx of Supernumerary Digit of Hand
Triphalangeal Thumbs in the Pediatric Population: Long Term Outcomes Following Surgical Intervention
A triphalangeal thumb is a thumb with three phalanges. The thumb often appears long and fingerlike, and can sometimes be in the same plane as the other fingers. Anatomically, the extra phalanx can have different shapes.
- Trial name
- NCT01409980
- Volunteers
- 3 people
- Sponsor
- University of Utah
Hip Surgery, Pericapsular Nerve
Pericapsular Nerve Group Block Versus Fascia Iliaca Block for Pediatric Hip Surgery
This compares the postoperative analgesic effect of ultrasound-guided pericapsular nerve group block (PENG) with ultrasound-guided fascia iliaca compartment block in pediatric patients undergoing hip surgery.
- Conditions
- Hip Surgery, Pericapsular Nerve, Fascia Iliaca
- Trial name
- NCT05460442
- Testing
- Caudal Block group, Pericapsular nerve group block, Fascia iliaca group
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Tanta University
Type 2 Diabetes Mellitus
PK Study of Dapagliflozin in Pediatric Subjects With T2DM
The primary purpose of this study is to evaluate the pharmacokinetics (PK) of Dapagliflozin in pediatric subjects with type 2 diabetes mellitus (T2DM)
- Trial name
- NCT01525238
- Testing
- Dapagliflozin
- Where
- 17 sites in United States, Mexico
- Volunteers
- 53 people
- Sponsor
- AstraZeneca
Pediatric Renal Stones
Efficacy and Safety of Flexible Ureteroscopy With Flexible Navigable Suction Ureteral Access Sheath Versus Mini-Percutaneous Nephrolithotomy With Vacuum-Assisted Access Sheath
Mini-percutaneous nephrolithotomy (mini-PCNL) and retrograde intrarenal surgery (RIRS) are both effective treatment modalities for renal calculi measuring up to 2.5 cm in pediatric patients, demonstrating similar efficacy and…
- Trial name
- NCT07763743
- Testing
- Flexible Ureteroscopy
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Ain Shams University
Adverse Drug Reactions
Influence of CYP2C19 Genotype on Safety and Efficacy of Voriconazole in Pediatric Patients With Hematologic Malignancy
Voriconazole is a drug used to treat invasive fungal infections. The amount of voriconazole in a person's blood helps to determine how effectively it treats an infection, and how safe it is.
- Trial name
- NCT04743544
- Testing
- Voriconazole
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Dokuz Eylul University
Coping Behavior, Emotional Distress
Creative Arts Diabetes Initiative for Youth/Young Adults Transitioning to Adult Care
The Creative Arts Diabetes Initiative will offer facilitated art therapy with a group/peer-support environment to two groups of youth/young adults, one with type 1 diabetes, and one with type 2 diabetes.
- Conditions
- Coping Behavior, Emotional Distress, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- CADI (NCT02790892)
- Testing
- Art therapy - pre and post test measures
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of Manitoba
Pediatric Obesity
Wellness and Weight Family Group Project
The purpose of the current study is examine the feasibility and efficacy of providing a behavioral family intervention in 30 youth 10 to 17 years of age who are obese and attending a multidisciplinary pediatric obesity clinic and…
- Trial name
- NCT02677792
- Testing
- Behavioral Family Intervention (BFI)
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Mississippi Medical Center
Urologic Diseases
Z-plasty and Heineke-Mikulicz Scrotoplasty in the Management of Penoscrotal Web
The goal of this clinical trial is to compare the surgical outcome of Z-scrotoplasty versus Heineke-Mikulicz scrotoplasty in the management of congenital penoscrotal web in pediatric age group.
- Trial name
- NCT05817760
- Testing
- Z-scrotoplasty, Heineke-Mikulicz scrotoplasty
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Egyptian Biomedical Research Network
Obesity, Obesity, Childhood
Community Based Obesity Prevention and Treatment Programme "6-10-14 for Health"
"6-10-14 for Health" is an integrated weight-loss intervention programme for obese children from Gdansk municipality. Both participants of the programme and their family members are offered a 12-month integrated intervention…
- Conditions
- Obesity, Obesity, Childhood, Health Program, Body Weight Changes
- Trial name
- NCT04143074
- Testing
- multidisciplinary behavioral intervention
- Where
- Poland
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Michał Brzeziński
Wassel IV Thumb Duplication
Study of Functional and Aesthetic Outcomes After Wassel IV Thumb Duplication Surgery in Pediatric Population, With a Follow-up of at Least One Year
The purpose of this study is to evaluate the functional and aesthetic outcomes in children with Wassel IV thumb duplication
- Trial name
- NCT06377670
- Testing
- Wassel IV Thumb Duplication Surgery
- Volunteers
- 30 people
- Sponsor
- University Hospital, Grenoble
Healthy
Assessment of Digital Radiograph Measurements of Hip,Spine and Lower Limbs
Research Protocol Assessment of Hip, Spine and Lower Limbs Digital Radiograph Measurements in Pediatric Population: using PACS integrated Computer Software (TraumaCad from OrthoCrat ™).
- Trial name
- NCT00782223
- Volunteers
- 50 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Epilepsy
SCN2A Polymorphisms Are Associated With Response to Valproic Acid in Paediatric Population(Pakistan)
The goal of this Observational study was to identify the effect of SCN2A gene polymorphism in the Paediatric epileptic Pakistani population.
- Trial name
- NCT06674070
- Testing
- Valproic Acid
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Riphah International University
Dehydration, Cardiac Output
Descriptive Study of Cardiac Output During Rehydration With Recombinant Human Hyaluronidase in Pediatrics
The purpose of this study is to non-invasively study the reflective changes in cardiac output as response to fluid therapy in the pediatric moderate hypovolemia/dehydrated pediatric patients using sub-q rehydration using Hylenex…
- Conditions
- Dehydration, Cardiac Output, Pediatrics
- Trial name
- Hylenex (NCT01139294)
- Testing
- Hylenex
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Pediatric Multiple Sclerosis
Mobile Attentional Bias Modification Training in Pediatric MS
This study will examine the feasibility of using a mobile ABMT application as a treatment modality in the Pediatric Multiple Sclerosis population.
- Trial name
- NCT04441229
- Testing
- ABMT mobile application
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- NYU Langone Health
Hip Dysplasia
Pericapsular Block Versus Trans Muscular Quadratus Lumborum Block in Patients Undergoing Correction of Hip Dysplasia
The aim of our study to compare the analgesic effect of pericapsular nerve group block combined with lateral femoral cutaneous nerve block and trans muscular quadratus Lumborum Block block perioperatively in pediatric patients…
- Trial name
- NCT06130761
- Testing
- Pericapsular Nerve Group Block Combined With Lateral Femoral Cutaneous Nerve Block, trans muscular quadratus lumborum block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Intracardiac Thrombus
Rivaroxaban for Intracardiac Thrombosis in the Pediatric Population
The goal of this observational study is to determine the efficacy of rivaroxaban treatment for intracardiac thrombi resolution in pediatric patients (< 16 years old) diagnosed with intracardiac thrombosis.
- Trial name
- NCT06371170
- Testing
- Rivaroxaban
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Azienda Ospedaliero, Universitaria Ospedali Riuniti
Hematologic Disorders, Oncologic Disorders
Rapid Infusion Rituximab, Hematologic, Oncologic, and Rheumatologic Disorders
Rituximab is frequently used in adult and pediatric cancers, blood disorders, lymphoma (a cancerous growth made up of lymphoid tissue), graft-versus-host-disease (complication that can occur after a stem cell or bone marrow…
- Conditions
- Hematologic Disorders, Oncologic Disorders, Rheumatologic Disorders
- Trial name
- NCT02484053
- Testing
- Rituximab
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Baylor College of Medicine
Childhood Obesity
Group Sessions and Web-based Treatment Targeting Children With Obesity Age 5-12 Years and Their Families
The aim of this study is to assess the efficacy of group sessions and a web-based program for children with obesity age 5-12 years and their parents.
- Trial name
- Webcop (NCT04013230)
- Testing
- Usual care, Web-COP
- Where
- 3 sites in Sweden
- Volunteers
- 60 people
- Sponsor
- Umeå University