Clinical trials: Pediatric Procedural Sedation
Pain, Procedural, Procedural Anxiety
Evaluating the Feasibility of VR for Pediatric Renal Biopsies
The purpose of this study is to assess the use of virtual reality (VR) as an adjunct or alternative to pharmacologic sedation in pediatric patients undergoing renal biopsy.
- Conditions
- Pain, Procedural, Procedural Anxiety, Sedation Complication
- Trial name
- NCT05267704
- Testing
- Oculus Go Virtual Reality Headset
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Ambulatory Surgery
REducing Anxiety in CHildren Undergoing Procedures
This is a small pilot, feasibility study designed as a quality improvement project. The purpose is to identify anxiety in children aged 4-12 years who will receive a sedated procedure and to see if the use of an iPad as a focused…
- Trial name
- REACH-UP! (NCT03054077)
- Testing
- iPad with downloaded games
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Conscious Sedation
Ondansetron Reduce Vomiting Associated With Ketamine PSA
Ondansetron, a commonly used anti-vomiting medication, may reduce the occurrence of vomiting associated with ketamine during procedural sedation in the pediatric emergency department.
- Trial name
- NCT00387556
- Testing
- Ondansetron
- Where
- United States
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Pain
Efficacy of IV Lidocaine at Alleviating Pain Associated With Propofol Infusion in Pediatric Patients Undergoing Sedation
This protocol describes a double-blind, placebo-controlled trial intended to demonstrate the effectiveness of lidocaine at reducing pain associated wiht propofol infusion for short-term deep sedation in children.
- Trial name
- NCT00786916
- Testing
- normal saline, lidocaine
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Akron Children's Hospital
Sedation
Intranasal Ketamine Versus Intramuscular Ketamine for Procedural Sedation in Pediatric Patients
The purpose of this study is to determine if intranasal ketamine is equally as effective and safe as intramuscular ketamine for procedural sedation in pediatric patients.
- Trial name
- NCT01170247
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Conscious Sedation Failure During Procedure
Ketamine Versus Etomidate for Procedural Sedation for Pediatric Orthopedic Reductions
There are multiple retrospective studies detailing the use of etomidate in pediatric procedural sedation but few to no prospective clinical trials.
- Trial name
- NCT00596050
- Testing
- ketamine and midazolam, etomidate, fentanyl, and lidocaine
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Drexel University College of Medicine
Laceration
Intranasal Ketamine for Procedural Sedation in Pediatric Laceration Repair
The purpose of this study is to compare how well three different doses of ketamine, given as a spray into the nose, help to sedate children and help them tolerate repairs of cuts on their faces.
- Trial name
- NCT00451724
- Testing
- Intranasal ketamine
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Sedation
Comparison of Oral Chloral Hydrate and Combination of Intranasal Dexmedetomidine and Ketamine for Procedural Sedation in Children
In Korea, oral chloral hydrate is still widely used for pediatric procedural sedation. The primary objective of the study is to evaluate the effect of intranasal dexmedetomidine (2mcg/kg) and ketamine (3mg/kg) on the…
- Trial name
- NCT04820205
- Testing
- Intranasal dexmedetomidine and ketamine, Oral chloral hydrate
- Where
- South Korea
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Inhalation Anesthesia
Comparing Nebulized Ketamine,Nebulized Ketamine and Precedex and IM Ketamine for Analgesia in Pediatric Burn
The present study compares efficacy of nebulised ketamine and combination of nebulised dexmedetomidine and ketamine and intramuscular ketamine for procedural sedation and analgesia in pediatric burn injuries
- Trial name
- NCT07086690
- Testing
- Group (1): Patients will receive nebulized ketamine (2 mg/kg), Group (2): Patients will receive nebulized combination of dexmedetomidine and ketamine (1 μg/kg + 1 mg/kg), Patients will receive intramuscular ketamine (4 mg/kg, intramuscularly) 15 mins before starting the procedure.
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Anxiety
High-Concentration Nitrous Oxide for Dental Procedural Sedation in Children
The use of nitrous oxide as a sedative agent is very common in pediatric dentistry. In concentrations up to 50% it is considered as mild sedation and it is very safe.
- Trial name
- NCT02886351
- Testing
- Nitrous Oxide
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bnai Zion Medical Center
Conscious Sedation, Distal Radius Fracture
IN Dexmedetomidine for Procedural Sedation in Pediatric Closed Reductions for Distal Forearm Fractures
The primary objective of this study is to evaluate the sedative, and analgesic effects of intranasal (IN) Dexmedetomidine (DEX) in children presenting to a Pediatric Emergency Department (PED) who undergo conscious sedation for…
- Trial name
- NCT03466242
- Testing
- Dexmedetomidine, Ketamine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Phoenix Children's Hospital
Sedation
Comparison of Oral Chloral Hydrate and Combination of Intranasal Dexmedetomidine and Ketamine for Rescue After Failed Pediatric Procedural Sedation
In Korea, oral chloral hydrate is still widely used for pediatric procedural sedation. The primary objective of the study is to evaluate the effect of intranasal dexmedetomidine (2mcg/kg) and ketamine (3mg/kg) on the success rate…
- Trial name
- NCT04822064
- Testing
- Intranasal dexmedetomidine and ketamine, Oral chloral hydrate
- Where
- South Korea
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Muscular Atrophy, Spinal, Child, Only
Procedural Sedation for Pediatric Patients With Spinal Muscular Atrophy
Background and Aim: Spinal muscular atrophy (SMA) is a neuromuscular disease characterized by progressive symmetrical weakness and atrophy of proximal muscles causing from degeneration of anterior horn cells of spinal cord.
- Conditions
- Muscular Atrophy, Spinal, Child, Only, Anesthesia
- Trial name
- NCT05291962
- Testing
- Retrospective observational study
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Satisfaction
Development and Validation of a Pediatric Procedural Sedation Satisfaction Survey
The quality of care associated with medical procedures, such as procedural sedation, has historically been assessed from the perspective of the healthcare professional, wherein the appropriateness of the services provided and the…
- Trial name
- NCT03468608
- Where
- Canada
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children