Clinical trials: Pediatric Renal Stones
Kidney Stone, Nephrolithiasis
Pediatric KIDney Stone (PKIDS) Care Improvement Network
The goals of this study are to improve the ability of pediatric patients and their caregivers to select surgical treatment options for kidney stones and to enable urologists to use techniques that result in the best outcomes for…
- Trial name
- PKIDS (NCT04285658)
- Testing
- Ureteroscopy, Percutaneous Nephrolithotomy, Shock Wave Lithotripsy
- Where
- 31 sites in United States, Canada
- Volunteers
- 1,290 people
- Sponsor
- Children's Hospital of Philadelphia
Pediatric Urolithiasis, Ureteral Stent-Related Symptoms
Comparison of Ureteral Stent Designs in Children With Kidney Stones
This study will compare two commonly used ureteral stents in children and adolescents undergoing staged treatment for kidney stones.
- Trial name
- NCT07742358
- Testing
- Polaris Ultra Ureteral Stent, Cook Double-J Ureteral Stent
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- The Hospital for Sick Children
Nephrocalcinosis
Epidemiology and Risk Factors of Nephrolithiasis and Nephrocalcinosis With Pediatric Onset
The aim of the study is to build a database of pediatric patients affected by nephrolithiasis or nephrocalcinosis in order to investigate their clinical and epidemiological characteristics.
- Trial name
- Calcolosi-kid (NCT07874087)
- Where
- Italy
- Volunteers
- 800 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Renal Stone, Kidney; Complications
Evaluation of Renal Oxygenation by NIRS in Pediatric Endourologic Stone Surgery
The study aims to compare renal oxygenation levels in retrograde intrarenal surgery (RIRS) and ureteroscopy (URS) procedures with a control group.
- Conditions
- Renal Stone, Kidney; Complications, Ureter Stone, Renal Oxygenation
- Trial name
- NCT06110247
- Testing
- NIRS, Taking a blood sample
- Where
- Turkey (Türkiye)
- Volunteers
- 136 people
- Sponsor
- Ankara City Hospital Bilkent
Stone, Kidney, Child, Only
Shock Wave Lithotripsy Using Fluoroscopic Versus Ultrasonic Localization
Epidemiological studies have shown a progressive increase in the incidence of pediatric urolithiasis over the past few decades.
- Trial name
- NCT05413603
- Testing
- ultrasonic focus Shock wave lithotripsy, fluoroscopic focus Shock wave lithotripsy
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Egymedicalpedia
Mini Percutaneous Nephrolithotomy, Retrograde Intrarenal Surgery
Mini Percutaneous Nephrolithotomy and Retrograde Intrarenal Surgery for Pediatric Renal Stones (10-30 mm)
This work aimed to compare the safety and efficacy of retrograde intrarenal surgery using single-use flexible ureteroscopy (FURS) with mini-percutaneous nephrolithotomy (PCNL) in children with renal stones measuring 10-30 mm.
- Conditions
- Mini Percutaneous Nephrolithotomy, Retrograde Intrarenal Surgery, Pediatric, Renal Stones
- Trial name
- NCT07836192
- Testing
- Mini percutaneous nephrolithotomy, Flexible ureteroscopy
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Tamsulosin, Extracorporeal Shock Wave Lithotripsy
The Efficacy and Safety of Medical Expulsive Therapy After Extracorporeal Shock Wave Lithotripsy (ESWL) in Pediatric Urolithiasis
The aim of this study is to evaluate the clinical efficacy and safety of MET after ESWL in pediatric urolithiasis.
- Conditions
- Tamsulosin, Extracorporeal Shock Wave Lithotripsy, Stone, Kidney, Stone, Urinary
- Trial name
- NCT05759767
- Testing
- Tamsulosin
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Mansoura University
Enteric Hyperoxaluria, Primary Hyperoxaluria
Study of ALLN-177 in Patients Aged 12 Years or Older With Enteric or Primary Hyperoxaluria and Hyperoxalemia
Evaluate the efficacy and safety of ALLN-177 in reducing plasma and urinary oxalate levels in adult and pediatric patients with enteric hyperoxaluria and hyperoxalemia or primary hyperoxaluria
- Conditions
- Enteric Hyperoxaluria, Primary Hyperoxaluria, Hyperoxalemia
- Trial name
- NCT03391804
- Testing
- ALLN-177
- Where
- 9 sites in United States, Germany and 1 more
- Volunteers
- 15 people
- Sponsor
- Allena Pharmaceuticals
Kidney Calculi
Flexible Ureteroscopy for Large Renal Stones in Children
This prospective single-arm interventional study evaluated the efficacy and safety of flexible ureteroscopy for the treatment of large renal stones measuring 2 cm or more in pediatric patients.
- Trial name
- NCT07780409
- Testing
- Flexible Ureteroscopic Stone Disintegration
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Pediatric Renal Stones
Efficacy and Safety of Flexible Ureteroscopy With Flexible Navigable Suction Ureteral Access Sheath Versus Mini-Percutaneous Nephrolithotomy With Vacuum-Assisted Access Sheath
Mini-percutaneous nephrolithotomy (mini-PCNL) and retrograde intrarenal surgery (RIRS) are both effective treatment modalities for renal calculi measuring up to 2.5 cm in pediatric patients, demonstrating similar efficacy and…
- Trial name
- NCT07763743
- Testing
- Flexible Ureteroscopy
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Ain Shams University
Renal Stone Disease
Intrarenal Pressure Monitoring During Pediatric Percutaneous Nephrolithotomy, and Its Impact on Post Operative Infectious Complications.
Monitoring of intrarenal pressure during pediatric percutaneous nephrolithotomy and its impact on post operative infectious complications.
- Trial name
- NCT07800546
- Testing
- Intrarenal pressure
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Renal Stone, Percutaneous
Erector Spinae Versus Paravertebral in Pediatric PCNL
To compare the efficacy of ultrasound-guided erector spinae plane block versus ultrasound-guided paravertebral block in pediatric patients undergoing percutaneous nephrolithotomy
- Conditions
- Renal Stone, Percutaneous, Nephrolithotomy
- Trial name
- NCT05589649
- Testing
- Erector spinae plane block, Paravertebral block
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Assiut University
Pediatric ALL, Stone, Urinary
Indications and Outcomes in Kidney-ureteral Pediatric Lithiasis: Experience of Parma
Incidence of paediatric urolithiasis is increasing in Europe and North America. Nowadays the management of stone disease is a common practice in not endemic country.
- Trial name
- NCT04605315
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Pediatric Renal Stone
Retrograde Intrarenal Surgery Versus Mini Percutaneous Nephrolithotomy
Pediatric nephrolithiasis accounts for approximately 2-3% of all stone disease cases, with recent reports indicating a rising prevalence of up to 10.6%. This increasing incidence poses a growing public health concern.
- Trial name
- NCT07700251
- Testing
- Retrograde Intrarenal Surgery
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- South Valley University
Pediatric Kidney Disease
Ultrasonic vs. Fluoroscopic Guided PNL in Pediatric Renal Stones
Percutaneous Nephrolithotomy (PNL) was accepted as a treatment modality for large renal stones since 1980. Although radiation exposure during PNL is within the safe limits for expert endourologist, the mutagenic hazard is still…
- Trial name
- NCT03250559
- Testing
- Percutaneous nephrolithotomy
- Where
- Egypt
- Volunteers
- 6 people
- Sponsor
- Assiut University
Pediatric Kidney Disease
Shockwave Lithotripsy (SWL) Versus SWL and Oral Dissolution Therapy (ODT) For Paediatrics Radiolucent Renal Stone
To conduct a RCT comparing SWL versus combined ODT and SWL as non-invasive methods for management of paediatrics radiolucent renal stone.
- Trial name
- NCT05896345
- Testing
- SWL, SWL and ODT
- Where
- Egypt
- Volunteers
- 76 people
- Sponsor
- Mansoura University
Acute Renal Failure, Anuria
Delayed or Direct Ureteroscopy in the Treatment of Pediatric Calcular Anuria
To compare staged ureteroscopy following initial urinary drainage versus direct ureteroscopy without initial urinary drainage in the treatment of obstructive calcular anuria with acute renal failure in children.
- Conditions
- Acute Renal Failure, Anuria, Obstructive Uropathy, Ureteric Stones
- Trial name
- NCT02139059
- Testing
- initial urinary drainage, direct ureteroscopy
- Where
- 2 sites in Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Renal Stone
Supine Percutaneous Nephrolithotomy
there is an increased incidence of renal stones, especially in the pediatric age group. the percutaneous approach in the pediatric age took a long time till it again accepted among surgeons worldwide.
- Trial name
- NCT04869969
- Testing
- percutaneous nephrolithotomy (supine position), percutaneous nephrolithotomy ( prone position)
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Renal Stone, Pediatric
Flexible Ureteroscopy Versus Mini- Percutaneous Nephrolithotomy in Management of Pediatric Renal Stones Less Than 2 cm
This single-center, prospective, two-arm randomized controlled trial included 58 patients younger than 18 years who were allocated 1:1 to Mini-PCNL or FURS between June 2023 and December 2024.
- Trial name
- NCT07870200
- Testing
- Group A :Flexible ureteroscope group, Group B : Mini perc group
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Elsayed Abdelhalim Elsayed
Stone, Kidney
Clinical Efficacy of Mini-PCNLversus RIRS for the Management of Upper Urinary Tract Calculus (1-2.5 cm)
The goal of this [ type of study:]prospective randomized clinical trial. The main question is to compare the outcomes of mini-percutaneous nephrolithotomy (m-PCNL) and retrograde intrarenal surgery (RIRS) in treating upper…
- Trial name
- NCT06031103
- Testing
- mini-PCNL procedure, RIRS procedure
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University