Clinical trials: Pelvic Prolapse
Pelvic Organ Prolapse
the Indications and Clinical Efficacy of Pelvic Organ Prolapse Surgery
One thousand patients with stage>2 POP are recruited. The patients are all received surgeries,such as transvaginal synthetic mesh surgery, the sacral fixation, tissue repair surgery and colpocleisis.
- Trial name
- NCT02599311
- Testing
- transvaginal synthetic mesh, Tolterodine
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Stress Incontinence Female, Pelvic Organ Prolapse
Sequence of Midurethral Sling Placement During Robotic Sacrocolpopexy
This study looks at the best time to place a midurethral sling (MUS), which is a small piece of mesh used to treat stress urinary incontinence (SUI) (leaking urine when you cough, laugh, or exercise).
- Trial name
- NCT07008898
- Testing
- Midurethral sling placed before robotic sacrocolpopexy, Midurethral sling placed after robotic sacrocolpopexy
- Where
- 2 sites in United States
- Volunteers
- 110 people
- Sponsor
- University of Alabama at Birmingham
Pelvic Organ Prolapse, Post Operative Pain
Postoperative Pain Management Following Robotic Assisted Sacrocolpopexy
In the effort to reduce postoperative opioid use, there has been increasing interest in developing multimodal pain regimens to better manage postoperative pain while minimizing opioid use and their subsequent side effects that…
- Trial name
- NCT06309693
- Testing
- Quadratus Lumborum (QL) Block, Enhanced Recovery After Surgical (ERAS) Protocol
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Alabama at Birmingham
Prolapse Genital
A Novel Assay for Predicting Surgical Outcomes in Pelvic Organ Prolapse
The research objective of this proposal is to investigate the clinical utility and validity of eLASV as a personalized marker for women's individual risk of recurrence for pelvic organ prolapse following advanced surgical…
- Trial name
- eLASV (NCT03534830)
- Testing
- MRI
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Rectal Prolapse
LVMR Versus PSR for External FTRPin Elderly Patients
In frail patients with external full-thickness rectal prolapse (FTRP), the exact postoperative recurrence and functional result outcomes difference between Laparoscopic ventral mesh rectopexy (LVMR) and perineal stapler resection…
- Trial name
- NCT05915936
- Testing
- LVMR, PSR
- Volunteers
- 330 people
- Sponsor
- Zagazig University
Genital Prolapse
Vaginal Estriol Before and Vaginal Surgery for Prolapse
The purpose of this study is to determine whether the vaginal estriol before vaginal surgery for pelvic statics disorders is more efficacy of no estriol treatment on vaginal health and quality of life.
- Trial name
- VSaE (NCT02906111)
- Testing
- estriol, vaginal surgery
- Volunteers
- 88 people
- Sponsor
- Salvatore Caruso
Cystocele, Vaginal Vault Prolapse
Laser Therapy in Managing Vaginal Prolapse
Efficacy of laser therapy in postmenopausal women with symptomatic prolapse stage >1. Assessment tools will include prolapse stage quantification system (POP-Q) and validated condition related questionnaires.
- Conditions
- Cystocele, Vaginal Vault Prolapse, Rectocele, Enterocele
- Trial name
- NCT03714607
- Testing
- Erbium Yttrium Aluminum Garnet (Er:YAG) laser
- Where
- Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Uterovaginal and Vaginal Vault Prolapse
A New Technique for Sacrospinous-Sacrotuberous Fixation for the Treatment of Uterovaginal and Vaginal Vault Prolapse
This prospective interventional randomized controlled trial is conducted to compare a new technique for Sacrospinous-Sacrotuberous fixation with the traditional sacrospinous ligament fixation technique for treatment of…
- Trial name
- NCT03487328
- Testing
- Sacrospinous-Sacrotuberous fixation
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Pelvic Organ Prolapse
Pelvic Floor Support After Laparoscopic Hysterectomy for Benign Conditions: A Randomized Controlled Trial Comparing Vaginal Cuff Closure Techniques
The purpose of this study is to learn about the effect of different vaginal cuff closure techniques on pelvic support after laparoscopic hysterectomy and robotic assisted laparoscopic hysterectomy for benign gynecologic…
- Trial name
- NCT03753516
- Testing
- Laparoscopic - Vaginal Cuff Closure, Vaginal- Vaginal Cuff Closure
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Walter Reed National Military Medical Center
Pelvic Organ Prolapse
Development Study Using Vaginal Tactile Imager
The objective is to evaluate and optimize tactile imaging technology in evaluation of tissue elasticity parameters in the female pelvis.
- Trial name
- NCT01111916
- Where
- 2 sites in United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Artann Laboratories
Vault Prolapse, Vaginal
An Institutional Audit of the Short Term Complications and Long Term Outcomes of Patients Undergoing Laparoscopic Sacrocolpopexy for Vault/cervical Prolapse.
An institutional audit of the short term complications and long term outcomes of patients undergoing laparoscopic sacrocolpopexy for vault/cervical prolapse.
- Trial name
- NCT04378400
- Testing
- Sacrocolpopexy
- Where
- Belgium
- Volunteers
- 250 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Pelvic Organ Prolapse
The Influence of Simultaneous Posterior Colporrhaphy and Perineoplasty on the Efficiency and Safety of Mesh-augmented Sacrospinal Fixation (Apical Sling) in Advanced POP Repair.
This is a prospective randomized controlled study, designed to assess the influence of posterior colporrhaphy and perineoplasty performed simultaneously with mesh-augmented sacrospinal fixation (apical sling) in advanced pelvic…
- Trial name
- NCT05422209
- Testing
- Mesh-augmented sacrospinal fixation with posterior colporrhaphy and perineoplasty., Mesh-augmented sacrospinal fixation with posterior colporrhaphy.
- Where
- Russia
- Volunteers
- 310 people
- Sponsor
- Saint Petersburg State University, Russia
Pelvic Organ Prolapse
Patient Education in the Clinical Management of Pessary
This study is a prospective, randomized, controlled, single-blinded, multi-center clinical trial. Symptomatic patients with pelvic organ prolapse (POP) stage II, III or IV arranged to undergo pessary treatment will be randomized…
- Trial name
- NCT06432218
- Testing
- video education, conventional education
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Peking Union Medical College Hospital
Pelvic Organ Prolapse, Stress Urinary Incontinence
Pessary Experience Study
Pessaries are silicone devices inserted into the vagina for treatment of pelvic organ prolapse or stress urinary incontinence. They are adequate treatment options for patients who are poor surgical candidates, those who decline…
- Trial name
- NCT06021769
- Testing
- Observational only
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Rectal Prolapse
A Modified Technique to Facilitate Pealing of the Rectal Mucosa in Delorme Operation
The aim of this study is to evaluate the investigator new modification for delorme procedure in patients with rectal prolapse , assessing intra-operative morbidity and recurrence rate .
- Trial name
- NCT02901210
- Testing
- Modified delorme procedure
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Yasser Mohamed Abdel-samii
Pelvic Organ Prolapse
Bowel Preparation and Pelvic Organ Prolapse Surgery
The purpose of this study is to find out if performing a bowel preparation prior to pelvic organ prolapse surgery has any effect on the return of bowel function after surgery.
- Trial name
- NCT00937430
- Testing
- Bowel preparation (Fleets enema)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- TriHealth Inc.
Vaginal Vault Prolapse, Uterine Prolapse
Laparoscopic Pectopexy and Laparoscopic Colporrhaphies in Pelvic Organ Prolapse Treatment
This prospective cohort study investigates the surgical outcomes of laparoscopic pectopexy and laparoscopic colporraphy performed at the Wellbeing Services County of South Ostrobothnia.
- Conditions
- Vaginal Vault Prolapse, Uterine Prolapse, Cystocele, Midline, Rectocele; Female
- Trial name
- NCT06902909
- Where
- Finland
- Volunteers
- 50 people
- Sponsor
- Tampere University Hospital
Pelvic Organ Prolapse
Continuous Locked Non-barbed Suture for Mesh Fixation During Laparoscopic Sacral Colpopexy for Severe Pelvic Organ Prolapse
This prospective randomized pilot study is aimed to verify if the operative time of a standard laparoscopic sacral colpopexy associated to subtotal hysterectomy for the treatment of POP could be further reduced using a continuous…
- Trial name
- NCT03427606
- Testing
- Continuous Locked Suture vs Traditional 5-points suture for Laparoscopic Sacral Colpopexy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Cardinale G. Panico
Pelvic Organ Prolapse
A Pilot Study to Evaluate the Clinical Effectiveness and Safety of the VFIX Device as Treatment for Apical Prolapse
The primary objective of this pilot study is to evaluate the safety and effectiveness of the VFIX device in maintaining vaginal apical support for at least 6 months in women with symptomatic apical prolapse (upper vaginal or…
- Trial name
- NCT01111409
- Testing
- VFIX Device
- Where
- 3 sites in Australia
- Volunteers
- 20 people
- Sponsor
- Ethicon, Inc.
Autoimmunity, Inguinal Hernia
ASIA-Mesh: a Pilot Study for Diagnostics and Treatment on ASIA Syndrome Caused by Polypropylene Mesh Implantation
In the present pilot study, a possible relation between the implantation of PP mesh for inguinal hernia, vaginal prolapse and SUI repair and subsequent systemic auto-immune complaints is investigated by testing immunologic and…
- Conditions
- Autoimmunity, Inguinal Hernia, Stress Urinary Incontinence, Pelvic Organ Prolapse
- Trial name
- NCT06363903
- Testing
- mesh allergy test, blood tests, Mesh removal
- Where
- 3 sites in Netherlands
- Volunteers
- 50 people
- Sponsor
- Maxima Medical Center