Clinical trials: Percutaneous Nephrolithotomy
Kidney Calculi (or Renal Calculi / Nephrolithiasis), Supine Mini Percutaneous Nephrolithotomy
Supine vs. Prone Mini-PCNL in Children
Percutaneous nephrolithotomy (PCNL) is an established intervention for large or ESWL-resistant renal stones in pediatric populations.
- Conditions
- Kidney Calculi (or Renal Calculi / Nephrolithiasis), Supine Mini Percutaneous Nephrolithotomy, Prone Mini Percutaneous Nephrolithotomy
- Trial name
- SUPRO-PED (NCT07887945)
- Testing
- Group A, Group B
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Fayoum University Hospital
Safety, Efficacy
Safety and Efficacy of Papillary Versus NonPapillary Access During Percutaneous Nephrolithotomy
This study aims to evaluate and compare the safety, efficacy, and clinical outcomes of papillary and non-papillary renal access during percutaneous nephrolithotomy (PCNL), and to determine whether non-papillary puncture can be…
- Conditions
- Safety, Efficacy, Papillary, NonPapillary
- Trial name
- NCT07855354
- Testing
- Papillary access puncture, Non-papillary access puncture
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Epidural Anesthesia, Percutaneous Nephrolithotomy (PCNL)
Predictors of Epidural Depth in Percutaneous Nephrolithotomy and Model Development
Accurate estimation of epidural depth is critical for safe epidural anesthesia during percutaneous nephrolithotomy (PCNL). Although various imaging modalities can predict epidural depth, they increase healthcare burden and are…
- Trial name
- NCT07697053
- Where
- China
- Volunteers
- 3,278 people
- Sponsor
- Tongji Hospital
Mini Percutaneous Nephrolithotomy, Retrograde Intrarenal Surgery
Mini Percutaneous Nephrolithotomy and Retrograde Intrarenal Surgery for Pediatric Renal Stones (10-30 mm)
This work aimed to compare the safety and efficacy of retrograde intrarenal surgery using single-use flexible ureteroscopy (FURS) with mini-percutaneous nephrolithotomy (PCNL) in children with renal stones measuring 10-30 mm.
- Conditions
- Mini Percutaneous Nephrolithotomy, Retrograde Intrarenal Surgery, Pediatric, Renal Stones
- Trial name
- NCT07836192
- Testing
- Mini percutaneous nephrolithotomy, Flexible ureteroscopy
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Percutaneous Nephrolithotomy
Flexible Nephroscopy-Assisted Single-Tract Versus Multi-Tract Percutaneous Nephrolithotomy for Complex Renal Stones
This randomized, parallel-group, non-inferiority trial will compare flexible nephroscopy-assisted single-tract percutaneous nephrolithotomy with conventional multi-tract percutaneous nephrolithotomy in patients with complex…
- Trial name
- NCT07753733
- Testing
- Flexible Nephroscopy-Assisted Single-Tract PCNL, Conventional Multi-Tract PCNL
- Where
- Egypt
- Volunteers
- 470 people
- Sponsor
- Al-Azhar University
Renal Stone, Extracorporeal Shockwave Lithotripsy
Mini- Percutaneous Nephrolithotomy Versus Extracorporeal Shock Wave Lithotripsy for High Density Renal Stones
Several studies were conducted to compare extracorporeal shockwave lithotripsy (SWL) and percutaneous nephrolithotomy (PNL) as treatment options for medium size lower caliceal high dense stones.
- Conditions
- Renal Stone, Extracorporeal Shockwave Lithotripsy, Percutaneous Nephrolithotomy
- Trial name
- NCT04346134
- Testing
- mini-PNL, SWL
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Al-Azhar University
Renal Stone, Percutaneous Nephrolithotomy
Mini-PNL, RIRS, and ESWL for Treatment of Medium-Sized, High-Density, Non-Lower Pole, Renal Stones
The optimal management of medium-sized renal stones remains quite challenging and continues to be contested. In the present study, the investigators will compare mini-PNL, RIRS and SWL in the treatment of non- lower pole, medium…
- Conditions
- Renal Stone, Percutaneous Nephrolithotomy, Retrograde Intrarenal Surgery, Extracorporeal Shockwave Lithotripsy
- Trial name
- NCT04856722
- Testing
- mini-PNL, RIRS, SWL
- Where
- Egypt
- Volunteers
- 253 people
- Sponsor
- Al-Azhar University
Percutaneous Nephrolithotomy (PCNL), Nephrolithiasis
Erector Spinae Plane Block for Percutaneous Nephrolithotomy
Percutaneous nephrolithotomy (PCNL) is an effective standard urological procedure for the fragmentation and removal of large renal calculi.
- Conditions
- Percutaneous Nephrolithotomy (PCNL), Nephrolithiasis, Renal Calculi
- Trial name
- NCT07457983
- Testing
- Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Fadime Tosun
Percutaneous Nephrolithotomy (PCNL)
Intrathecal Fentanyl and Dexmedetomidine Added to Bupivacaine for Subarachnoid Anaesthesia for Percutaneous Nephrolithotomy
Regular bupivacaine dosages are linked to considerable sympathetic block, as well as persistent and severe sensory and motor block, which may not be desired for certain individuals.
- Trial name
- NCT06957301
- Testing
- Intrathecal Fentanyl Group (F), intrathecal dexmedetomidine group(D)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Anesthesia Techniques, Percutaneous Nephrolithotomy
Effects of Spinal vs General Anesthesia on Systemic Inflammation in PCNL
This observational study aims to compare the effects of spinal and general anesthesia on perioperative systemic inflammatory response in patients undergoing percutaneous nephrolithotomy (PCNL).
- Conditions
- Anesthesia Techniques, Percutaneous Nephrolithotomy, Systemic Inflammation
- Trial name
- PCNL-ANES-INF (NCT07326670)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Percutaneous Nephrolithotomy (PNL), Nephrolithiasis
Two Bupivacaine Concentrations for Erector Spinae Plane Block in Percutaneous Nephrolithotomy
People who undergo percutaneous nephrolithotomy (PNL), a procedure used to remove kidney stones, often experience pain after surgery.
- Trial name
- ESPB-PNL (NCT07653230)
- Testing
- Erector spinae plane block (ESPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Education and Research Hospital
Postoperative Pain, Percutaneous Nephrolithotomy
The Effectiveness of Quadro İliac Plane Block in Percutaneous Nephrolithotomies
Our aim was to investigate the effect of quadro iliac plane block on postoperative analgesia in patients undergoing percutaneous nephrolithotomy surgery and to determine which areas of the skin this block anesthetizes.
- Trial name
- NCT07203859
- Testing
- Quadro-İliac Plane Block(QİPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cumhuriyet University
Kidney Stones, Surgical Blood Loss
Combined Intravenous and Irrigation Tranexamic Acid During Percutaneous Nephrolithotomy
Percutaneous nephrolithotomy is a minimally invasive surgical procedure used to remove large kidney stones. Although it is an effective treatment, bleeding during and after the procedure remains one of the main concerns and may…
- Conditions
- Kidney Stones, Surgical Blood Loss, Percutaneous Nephrolithotomy
- Trial name
- NCT07582341
- Testing
- Tranexamic acid, Normal Saline
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Benha University
Nephrolithotomy, Percutaneous
ESP Block vs Control for Pain Control Following Percutaneous Nephrolithotomy
The purpose of this study is to investigate the use of the erector spinae (ESP) block in reducing the morphine milligram equivalent (MME) consumption post percutaneous nephrolithotomy. Objectives: 1.
- Trial name
- NCT05024344
- Testing
- Erector Spinae Plane Block, Ropivacaine 0.5% Injectable Solution, Dexamethasone
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- University of Tennessee Medical Center
Percutaneous Nephrolithotomy (PCNL), Perioperative Analgesia
Anterior QLB for PCNL
Aim: In this study, we primarily aimed to determine the effect of anterior Quadratus Lumborum Block (QLB) on intraoperative and postoperative opioid consumption in patients undergoing percutaneous nephrolithotomy (PCNL) surgery…
- Conditions
- Percutaneous Nephrolithotomy (PCNL), Perioperative Analgesia, Quadratus Lumborum Block, Opioid Consumption
- Trial name
- NCT07487415
- Testing
- ANTERİOR QUADRATUS LUMBORUM BLOCK ( anterior QLB)
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Zonguldak Bulent Ecevit University
Urolithiasis, Percutaneous Nephrolithotomy (PCNL)
A Multifunctional Miniature Nephroscope for Percutaneous Nephrolithotomy
The goal of this clinical trial is to introduce a novel multifunctional miniature endoscopic system, namely "Aircraft Nephroscope", for percutaneous nephrolithotomy (PCNL) to treat the patients with urolithiasis.
- Trial name
- NCT07471711
- Testing
- percutaneous nephrolithotomy
- Where
- China
- Volunteers
- 216 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Ureterorenoscopic Lithotripsy, Transurethral Resection of the Bladder
Inhalational Agents Versus Dexmedetomidine for Maintenance of General Anesthesia
The climate crisis and environmental pollution are escalating day by day, making the reduction of carbon footprints increasingly important both on an individual and industrial level.
- Conditions
- Ureterorenoscopic Lithotripsy, Transurethral Resection of the Bladder, Percutaneous Nephrolithotomy, Transurethral Resection of the Prostate
- Trial name
- NCT07363681
- Testing
- Dexmedetomidine + Remifentanil, Desflurane + Remifentanil
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Percutaneous Nephrolithotomy
Application of 3DSlicer Technology in Percutaneous Nephrolithotomy Surgery.
Objectives: Percutaneous nephrolithotomy (PCNL) has become a widely used technique for managing renal calculi. However, the rate of residual stones remains high.
- Trial name
- NCT07299643
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Ting Huang
Percutaneous Nephrolithotomy (PCNL), Renal Stone Disease
Comparative Study Between One-Shot Dilatation Versus Serial Dilatation Techniques for Access in Percutaneous Nephrolithotomy in Adult Patients
This comparative study aims to compare and assess the safety, efficacy, outcome, feasibility, intraoperative and postoperative complications of one-shot dilatation versus serial dilatation techniques for access during…
- Trial name
- NCT07279389
- Testing
- renal dilatation by one-shot dilatation technique, renal dilatation by metallic telescopic dilators (Alken)., renal dilatation by sequential fascial dilators (Amplatz)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Percutaneous Nephrolithotomy (PCNL), Surgical Positioning
Hemodynamic Effects of Surgical Position in Prone vs. Supine Percutaneous Nephrolithotomy
This prospective, randomized controlled study evaluates the hemodynamic effects of prone and supine positions during percutaneous nephrolithotomy (PNL) for large kidney stones.
- Conditions
- Percutaneous Nephrolithotomy (PCNL), Surgical Positioning, Prone Position, Supine Position
- Trial name
- NCT07138872
- Testing
- Prone Position Percutaneous Nephrolithotomy, Supine Position Percutaneous Nephrolithotomy (Galdakao-modified Valdivia)
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital