Clinical trials: Performance Enhancing
Safety and Impact of Medically Supervised Performance Enhancing Substance Usage in Healthy Elite Athletes
Impact of Medically Supervised Performance-Enhancing Substances (PES) on Elite Athletes
Objectives: The primary objective is to assess the safety and tolerability of medical drugs with the potential to enhance performance (PES) in professional athletes over a 5.5 year period, encompassing a 25-week PES Exposure…
- Trial name
- ASCEND001 (NCT07568574)
- Testing
- Testosterone Enanthate, Testosterone Cypionate, Testosterone Propionate
- Where
- United Arab Emirates
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Enhanced Emirates Limited
Bone Regeneration Following Wisdom Teeth Extraction
A Split-Blind Clinical Investigation to Compare the Performance and Safety of Inion GTR™ Biodegradable Membrane System to Resorbable Bilayer Bio-Gide®-Membrane of Geistlich Biomaterials in Enhancing Bone Regeneration After Removal of Wisdom Teeth.
The purpose of this study was to evaluate by histology and histomorphometry, thirty human osseous biopsies sampled from fifteen patients (2 biopsies per patient) following 3 months of implantation.
- Trial name
- NCT00727818
- Testing
- guided bone regeneration
- Where
- Switzerland
- Sponsor
- University of Zurich
Athlete Assessment, Body Composition
Resting Metabolic Rate in Bodybuilders Using Performance-Enhancing Drugs
Bodybuilders present unique body composition profiles, characterized by high fat-free mass and very low levels of body fat. In addition, many competitive and non-competitive athletes use anabolic-androgenic steroids (AAS) and…
- Trial name
- Non applicable (NCT07878052)
- Testing
- No Intervention: Observational Cohort
- Where
- Portugal
- Volunteers
- 62 people
- Sponsor
- Atlantica - Instituto Universitario
PERFORMANCE-ENHANCING EFFECT
Effects of Novel Sodium Bicarbonate Ingestion of Buffering Capacity
One purpose of the present study was to evaluate the effect of elevating serum bicarbonate concentration more than had been achieved in previous studies without inducing potentially ergolytic GI distress.
- Trial name
- NCT03813329
- Testing
- Modified Sodium Bicarbonate, Acute Sodium Bicarbonate
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Long Island University
Mild Cognitive Impairment
Computerized Memory Enhancing Treatment in MCI
The investigators propose to apply neuroplasticity-based computerized cognitive remediation (nCCR) to improve memory function in patients with Mild Cognitive Impairment (MCI).
- Trial name
- COMET (NCT05332522)
- Testing
- Neuroplasticity-based Computerized Cognitive Remediation
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Vanderbilt University Medical Center
Stability, Jumping Performance
Enhancing Stability and Jumping Skills Through Combined Static and Dynamic Balance Training in Female Chinese University-Level Gymnastics Beginners
This study aims to investigate the effects of different balance training programs (dynamic, static, combined dynamic and static) on the stability, jumping skills, and gymnastic movement skills of female university students who…
- Conditions
- Stability, Jumping Performance, Balance Training, Gymnastics Injury, Motor Learning, Balance
- Trial name
- NCT07288645
- Testing
- balance group
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yi Wang
Neurologic Ambulation Disorder
Interactive Intensive Gait Training in Walking Limitations
Gait-MAP is a prospective, randomized, single-blind clinical trial designed to evaluate the effectiveness of an Intensive Interactive Gait Training (IIGT) program in adults with neurological conditions associated with pyramidal…
- Trial name
- Gait-MAP (NCT07899528)
- Testing
- Intensive Interactive Gait Training, Conventional Gait Rehabilitation
- Where
- Italy
- Volunteers
- 112 people
- Sponsor
- IRCCS San Raffaele Roma
Doping in Sport, Performance Enhancing Product Use
Videogame for the Prevention of Doping and Supplement Abuse in Teenage Athletes
The purpose of this research is to test the effectiveness of an interactive doping education videogame among student athletes. Specifically, the game will teach athletes aged 13-16 years about the risks of doping and will foster…
- Trial name
- NCT04203992
- Testing
- Videogame, Control
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- McGill University
Acute Kidney Failure, Chronic Kidney Diseases
Enhancing Fluid Transfer Through the Skin, by Increased Sweat Rate, on Hemodialysis Patients
To demonstrate safety and performance of AquaPass System for improving fluid balance in hemo-dialysis patients, by increasing fluid loss via the skin.
- Trial name
- NCT06358365
- Testing
- The AquaPass System
- Where
- Israel
- Volunteers
- 5 people
- Sponsor
- AquaPass Medical Ltd.
Myocardial Injury After Non-cardiac Surgery, Submaximal Exercise Performance
Submaximal Cardiopulmonary Exercise Testing for Detection of Myocardial Injury After Noncardiac Surgery
The goal of this clinical trial is to learn whether physicians can associate evidence of myocardial injury after surgery with findings obtained from submaximal cardiopulmonary exercise testing.
- Conditions
- Myocardial Injury After Non-cardiac Surgery, Submaximal Exercise Performance, Preoperative Period
- Trial name
- EnhanceMINS (NCT06474754)
- Testing
- High-sensitivity troponin, serum, Submaximal Cardiopulmonary Exercise Testing, Duke Activity Status Index
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Yale University
Attention Deficit Hyperactivity Disorder
Enhancing ADHD Driving Performance With Stimulant Medication
Among children, attention-deficit/hyperactivity disorder (ADHD) is associated with an increased risk for accidents, especially bicycle and pedestrian (Leibson 2001; Jensen 1988; DiScala 1998).
- Trial name
- NCT00572026
- Testing
- Methylphenidate Transdermal System
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Virginia
Improving Body Composition, Novel Natural Gym Nutrient Formulation
Formulation, Phytochemical Characterization, and Clinical Assessment of a Novel Natural Supplement Targeting Body Composition in Physically Active Individuals
This study aims to evaluate the efficacy of a novel natural gym nutrient formulation (NNS) in improving body composition in physically active individuals.
- Conditions
- Improving Body Composition, Novel Natural Gym Nutrient Formulation, Increase Muscle Mass, Reduce Body Fat Percentage
- Trial name
- NSCM (NCT07038135)
- Testing
- Novel Natural Supplement (NNS)
- Where
- Iraq
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Sulaimani Polytechnic University
Performance Enhancing Product Use
Effect of Creatine and Caffeine on Muscle Performance
To determine if creatine and caffeine can be co-supplemented without inhibiting the effects of creatine.
- Trial name
- NCT04290819
- Testing
- Creatine Monohydrate, Creatine Monohydrate and Caffeine, Caffeine
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Regina
Dialysis; Complications, Performance Enhancing Product Use
Effects of Short Term Creatine Supplementation in Hemodialysis Patients
Adult patients undergoing chronic dialysis therapy for at least three months were selected. A physical function assessment was conducted, including the Short Physical Performance Battery (SPPB) and a handgrip strength test.
- Trial name
- NCT07033611
- Testing
- Creatine
- Where
- Chile
- Volunteers
- 18 people
- Sponsor
- Carla Basualto Alarcón
Performance Enhancing Product Use, Sleep
Optimizing Volunteer Comfort for Transcranial Electrical Stimulation (TES): An Assessment
Transcranial electrical stimulation (TES) utilizing weak electrical fields (<5 milliamps of current - as proposed in the present pilot study) is an extremely safe therapeutic technique in use for over 40 years.
- Trial name
- TES (NCT04474015)
- Testing
- transcranial electric stimulation
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- U.S. Army Medical Research and Development Command
Schizophrenia
Enhancing Prefrontal Oscillations and Working Memory in Early-course Schizophrenia
This study will investigate the effects of intermittent Theta Burst Stimulation (iTBS) on natural oscillatory frequency of the dorsolateral prefrontal cortex (DLPFC) and working memory in early-course schizophrenia (EC-SCZ).
- Trial name
- REDOCS (NCT05102929)
- Testing
- active intermittent Theta Burst Stimulation (iTBS)
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Fabio Ferrarelli
Chronic Heart Failure
Effect of Enhanced Sweat Rate on the Safety and Edema Status of Chronic Edematous Patients
The purpose of this study is to demonstrate safety and performance of AquaPass System for enhancing fluid transfer through the skin, by increased sweat rate, in edematous patients.
- Trial name
- NCT04578353
- Testing
- The AquaPass System
- Where
- Israel
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- AquaPass Medical Ltd.
Children Receiving Early Intervention, Visual Perception Performance
The Effectiveness of Telehealth-Based Family-Centered Early Intervention
Background: Children with developmental delays or sensory processing disorders (SPD) face challenges in processing and integrating sensory information from their environment, which can lead to behavioral, learning, and social…
- Conditions
- Children Receiving Early Intervention, Visual Perception Performance, Effects of Posture and Movement
- Trial name
- NCT06615895
- Testing
- Telehealth home activity
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Bronchoconstriction, Inhaled Salbutamol
Salbutamol, Pharmacogenetics and Breathing Mechanics
Athletes using asthma medications called β2-agonists win a disproportionately high number of medals at Olympic Games. Due to a large variety in the genes that affect how individuals respond to β2-agonists, the investigators will…
- Conditions
- Bronchoconstriction, Inhaled Salbutamol, Cycling Performance
- Trial name
- NCT01903785
- Testing
- Salbutamol
- Where
- Canada
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Burnout, Professional
Understanding Performance: Enhancing Recovery as Surgeons
Reliably achieving peak performance requires balancing the strain of the prior day with sufficient recovery to be ready for the next day.
- Trial name
- ERAS (NCT05029674)
- Testing
- Whoop
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Stanford University