Clinical trials: Perfusion
Perfusion Index, Position Differences
Evaluation Of The Effects Of Changes In Operating Table Position On Perfusion Index And Spinal Anesthesia
The aim of this observational study is to investigate how table position affects the development of block in patients undergoing spinal anesthesia. Perfusion index measurements will be used to answer this question.
- Trial name
- Perfusion (NCT07400185)
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Enes Celik
Healthy Adults
Myocardial Blood Volume Measurement by Real-Time Myocardial Perfusion Echocardiography Correlates to Myocardial Compressibility by Cardiac Magnetic Resonance Imaging in Healthy Subjects
This study is being done to find out the normal amount of blood within the heart muscle and the variations in this blood flow between a cardiac MRI and TTE.
- Trial name
- NCT04724304
- Testing
- Real-Time Myocardial Echocardiography (RTMPE), Magnetic resonance image (MRI)
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Psoriasis
Effect of Chronic Inflammation on Myocardial Perfusion and Function
Background: Heart failure (HF) is a public health burden. Studies have shown a link between inflammation, myocardial dysfunction, and HF.
- Trial name
- NCT04870827
- Testing
- 13N Amonia
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Physical Activity, Aging
Independent Walking for Brain Health
Physical activity interventions with older adults can improve brain health; however most interventions have been performed in gym-like settings that reach a small sector of the senior population.
- Trial name
- NCT03058146
- Testing
- Mobile Health Walking Condition, Healthy Aging Education Condition
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Pulmonary Embolism Acute
Pulsatile Electrical Impedance Tomography for Diagnosis and Monitoring of Acute Pulmonary Embolism
This multicenter observational diagnostic study aims to evaluate pulsatile electrical impedance tomography (EIT) for the diagnosis and monitoring of acute pulmonary embolism.
- Trial name
- EIT-PE (NCT07724197)
- Testing
- Pulsatile Electrical Impedance Tomography
- Where
- 4 sites in China
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Heart Failure With Reduced Ejection Fraction (HFrEF), Renal Impairment
AZD3427 Effects on Renal Perfusion in Heart Failure Patients With Reduced Ejection Fraction and Renal Impairment
The present study is designed to test the effect of AZD3427 on renal perfusion in participants with heart failure and reduced eGFR (30 to 90 mL/min/1.73m2).
- Trial name
- Re-PERFUSE (NCT06611423)
- Testing
- AZD3427, Dopamine, Radiolabelled ligand
- Where
- Sweden
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Kawasaki Disease, Cardiovascular Disease
Magnetic Resonance Myocardial Stress Perfusion in Pediatric Patients with Cardiovascular Disease
the goal of this observational study is to evaluate myocardial ischemia and myocardial microcirculation dysfunction in children with cardiovascular disease by myocardial stress perfusion imaging.
- Conditions
- Kawasaki Disease, Cardiovascular Disease, Anomalous Origin of Coronary Artery
- Trial name
- NCT06641843
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- West China Second University Hospital
Skin Flap Necrosis, Perfusion; Complications
Feasibility of the IC-Flow Device for Fluorescent Perfusion Evaluation During Feasibility of the IC-Flow Device
1. Primary Objective: Demonstrate that the IC-Flow Imaging device with Indocyanine Green (ICG) is a feasible technique when visualizing and identifying perfusion of organs when compared to The KARL STORZ VITOM II ICG System…
- Trial name
- IC-Flow (NCT03860493)
- Testing
- Perfusion evaluation with indocyanine green
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Hypertension
Effects of Nebivolol on Skeletal Muscle During Exercise in Hypertensive Patients
The purpose of this study is to determine if Nebivolol improves microvascular perfusion in skeletal muscle during exercise in hypertensive patients and whether this improvement is accompanied by reduction in vascular oxidative…
- Trial name
- NCT01501929
- Testing
- Metoprolol succinate, Nebivolol, Non-invasive measurement of Cardiac Output (CO)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Rest Gated Myocardial Perfusion Imaging in Heart Failure
18F-MFBG Cardiac Imaging for Heart Failure Administration
The clinical feasibility of 18F-FMBG cardiac PET imaging will be observed in sympathetic nervous system activity in patients with heart failure, predicted cardiac events, guided ICD implantation, and evaluated therapy efficiency.
- Trial name
- NCT06149195
- Testing
- Standard medical care for heart failure
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sichuan Provincial People's Hospital
Acute Myeloid Leukemia
Bone Marrow Angiogenesis in Acute Myeloid Leukemia - Evaluated by Dynamic Contrast Enhanced Magnetic Resonance (MR) Image
In malignant or neoplastic disease, angiogenesis is defined as the generation of new capillaries from preexisting blood vessels, e.g. by sprouting or by intusseption.
- Trial name
- NCT00172562
- Where
- Taiwan
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Free Tissue Flaps
Detection of Flap Ischemia Using Interstitial Glucose Monitor
A simple device that objectively assesses flap perfusion - either as a stand-alone tool or an adjunct to the current monitoring method - would be a tremendous improvement in detection of early postoperative flap ischemia and, in…
- Trial name
- NCT02604069
- Testing
- Continuous Glucose Monitor
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Upper Extremity Fracture, Regional Anesthesia
Tissue Perfusion for Different Approaches of Brachial Plexus Block
To compare the two different approaches of infraclavicular brachial plexus block in forearm, wrist and hand surgery in terms of perfusion index, tissue oxygenation, sensory and motor block onset time and total effect time, first…
- Conditions
- Upper Extremity Fracture, Regional Anesthesia, Brachial Plexus Blocks, Perfusion Index
- Trial name
- NCT04764591
- Testing
- Lateral sagittal approach, Costoclavicular approach
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Pulmonary Arterial Hypertension
Evaluation of Pulmonary Perfusion Heterogeneity and Compliance in Patients With Pulmonary Hypertension Using Positron Emission Tomography Imaging
The purpose of the study is to find out how the blood flow changes in the lungs of people with pulmonary hypertension compared to healthy individuals without pulmonary hypertension.
- Trial name
- NCT01461343
- Testing
- CT imaging, functional PET imaging
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Cholinergic Function
Assessment of Cholinergic and Cognitive Function Using Pharmacologic ASL-Perfusion MRI
This research study will look at how medications affect the pattern of blood flow in the brain. This study will use a special type of MRI (magnetic resonance imaging) scan called perfusion MRI to make measurements of cerebral…
- Trial name
- NCT01379001
- Testing
- Scopolamine, Donepezil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hebrew SeniorLife
Pulmonary Ventilation, Pulmonary Perfusion
The Study of Regional Lung Ventilation-perfusion by EIT
This is a prospective observational trial. The purpose of this study is to explore the feasibility of EIT monitoring pulmonary blood flow and the consistency and difference between EIT monitoring pulmonary local ventilation blood…
- Trial name
- NCT05105932
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Peripheral Perfusion
DiCART TM Device for Capillary Refill Time Measurement
To estimate peripheral perfusion in shock state, international guidelines recommend the use of capillary refill time, and practitioners currently evaluates it at bedside.
- Trial name
- DICART-VS (NCT04538612)
- Testing
- measure capillary refill time
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Heart Failure, Diastolic, Diastolic Heart Failure
Myocardial Perfusion, Oxidative Metabolism, and Fibrosis in HFpEF
Unlike heart failure with reduced ejection fraction (HFrEF) where several medicines and devices have been demonstrated to reduce mortality, no such therapies have been identified in HFpEF.
- Conditions
- Heart Failure, Diastolic, Diastolic Heart Failure, Hypertension
- Trial name
- HFpEF-PRoF (NCT02589977)
- Testing
- regadenoson
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Marvin W. Kronenberg, M.D.
Chronic Diabetic Foot Ulcers
Pilot Study on Auricular Vagus Nerve Stimulation Effects in Chronic Diabetic Wounds
The purpose of this pilot study is to evaluate the effect of auricular autonomous nervous system stimulation on vital parameters of wound healing in diabetics.
- Trial name
- NCT02098447
- Testing
- PrimeStim
- Where
- Austria
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Alzheimer's Disease
Statin Effects on Beta-Amyloid and Cerebral Perfusion in Adults at Risk for Alzheimer's Disease
The purpose of the research is to see how simvastatin affects a substance in the body called beta-amyloid. Beta-amyloid is found in the brain and in the liquid around the brain and spinal cord.
- Trial name
- SHARP (NCT00939822)
- Testing
- Simvastatin
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison