Clinical trials: Perfusion
Healthy Brain Perfusion
Improving Human Cerebrovascular Function Using Acute Intermittent Hypoxia
This study uses magnetic resonance imaging to determine whether 3 weeks of repeated exposure to Acute Intermittent Hypoxia can improve brain blood flow or blood flow regulation in healthy adults.
- Trial name
- NCT05164705
- Testing
- Acute Intermittent Hypoxia
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Coronary Artery Disease, Myocardial Perfusion Abnormalities
Regadenoson R-T Perfusion Imaging Trial
To exam the feasibility and accuracy of Regadenoson real time perfusion (RTPE) Imaging during vasodilator stress with Regadenoson for detection of significant coronary artery disease (CAD) in patients scheduled to undergo…
- Trial name
- NCT00837369
- Testing
- Regadenoson
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Nebraska
Coronary Artery Disease, Myocardial Perfusion Abnormalities
Regadenoson Real Time Perfusion Imaging Trial-Optison
The purpose if this study is to examine how effective Regadenoson is in detecting coronary artery disease during a stress echocardiogram when Optison is administered.
- Trial name
- NCT01489176
- Testing
- Regadenoson; Optison
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of Nebraska
Perfusion; Complications
Evaluation of Capillary Refill Index
Comparison of a peripheral perfusion assessment method using a pulse oximeter to the conventional capillary refill time visually assessed by a clinician.
- Trial name
- CRI (NCT04144166)
- Testing
- capillary refill index (CRI)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Nihon Kohden
Circulatory Perfusion Disorder, Congenital Heart Disease
Early Use of Vasopressin in Post-Fontan Management
This is an investigator initiated, prospective, single-center, double-blinded, randomized, placebo-controlled trial of post-operative low dose vasopressin infusions as an early treatment of low systemic perfusion in pediatric…
- Conditions
- Circulatory Perfusion Disorder, Congenital Heart Disease, Single-ventricle
- Trial name
- VAMP (NCT03088345)
- Testing
- Vasopressin, Arginine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical College of Wisconsin
Perfusion; Complications
The Effect of Nitroglycerin Ointment, Fluorescent Angiography, and Incisional Negative Pressure Wound Therapy on Mastectomy Skin Flap Perfusion-Related Problems
This is a randomized study using a variety of techniques to compare and examine blood flow to the remaining skin after mastectomy. All treatments being used are considered standard of care and are not experimental.
- Trial name
- NCT03716050
- Testing
- Nitroglycerin, Negative Pressure Wound Therapy/ Wound VAC, Fluorescent Angiography with indocyanine-green (not to exceed 5mg/kg)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Wake Forest University Health Sciences
Pressure Distribution, Military Litters
NATO Litter: Fluid Immersion System (FIS) Versus Traditional Mattress for Pressure Dispersion
The purpose of this study is to measure peak skin interface pressures and the total area of the body exposed to skin interface pressure above 30 mm Hg at different areas of the body in the supine position on two different support…
- Conditions
- Pressure Distribution, Military Litters, Peak Pressure Index, Total Surface Area
- Trial name
- NCT03483623
- Testing
- NATO WELP combination, NATO FIS combination, RAVEN WELP combination
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- David Grant U.S. Air Force Medical Center
Ventilation Perfusion Mismatch
Effect of Alveolar Minute Ventilation on Respiratory Gas Heat Content
This is a single site, prospective, non-blinded, non-randomized, non-interventional study designed to evaluate the effect of changes in alveolar minute ventilation on the measurement of respiratory heat loss (enthalpy).
- Trial name
- NCT01943227
- Testing
- controlled positive pressure ventilation 9ml/kg tidal volume, controlled positive pressure ventilation 6ml/kg tidal volume
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Davis
Head Injury, Intracranial Pathology
Effect of Intrathoracic Pressure Regulation on Decreased Cerebral Perfusion (4hour)
The purpose of the study is to evaluate the physiological response to application of the Intrathoracic Pressure Regulator (ITPR) in patients with compromised cerebral circulation.
- Conditions
- Head Injury, Intracranial Pathology, Compromised Cerebral Perfusion
- Trial name
- NCT02388880
- Testing
- ITPR
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Advanced Circulatory Systems
Head Injury, Intracranial Pathology
Effect of Intrathoracic Pressure Regulation on Decreased Cerebral Perfusion
The purpose of the study is to evaluate the physiological response to application of the Intrathoracic Pressure Regulator (ITPR) in patients with compromised cerebral circulation.
- Conditions
- Head Injury, Intracranial Pathology, Compromised Cerebral Perfusion
- Trial name
- NCT01824576
- Testing
- ITPR
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- Advanced Circulatory Systems
Poor Peripheral Perfusion
Magnetic Resonance Imaging (MRI) to Assess Radial Artery Compression and Arterial Perfusion While TR Band is Applied
Subjects' radial artery diameters and plethysmography waveforms will be recorded by MRI and pulse oxymetry at varying levels of radial artery compression by the Terumo TR Band.
- Trial name
- NCT02478671
- Testing
- TR Band
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Terumo Medical Corporation
Myocardial Perfusion Imaging, Myocardial Ischemia
Effect of Ranolazine on Myocardial Perfusion Assessed by Serial Quantitative Exercise SPECT Imaging
This study enrolled participants with documented exercise-induced myocardial ischemia in order to evaluate whether ranolazine, when taken prior to exercise, can improve blood flow to the heart (myocardial perfusion), as assessed…
- Trial name
- NCT01221272
- Testing
- Ranolazine, SPECT MPI, Exercise
- Where
- 43 sites in United States, Canada and 6 more
- Volunteers
- 81 people
- Sponsor
- Gilead Sciences
Myocardial Perfusion Imaging, Magnetic Resonance Imaging
Myocardial Perfusion MRI
The object of this study is to compare four different dosages of Gadavist 1.0 in cardiac Magnetic Resonance Tomography (MRT) imaging with the imaging results of a cardiac SPECT examination in terms of diagnostic quality.
- Trial name
- NCT01490294
- Testing
- Gadobutrol (Gadavist,Gadovist, BAY86-4875)
- Where
- 14 sites in Austria, Germany and 2 more
- Volunteers
- 232 people
- Sponsor
- Bayer