Clinical trials: Peri Implantitis
Peri-Implantitis
Therapeutic Peri-implant Maintenance with Laser Therapy
The present study represents an extension of the previously concluded randomized clinical trial "Laser-Assisted Regenerative Surgical Therapy for Peri-implantitis" (HUM00124386).
- Trial name
- NCT04251793
- Testing
- Observation
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Michigan
Peri-Implantitis
The Morphology of the Peri-Implantitis Defects: A Cone-Beam Computed Analysis
To study the morphology of the peri-implant defects using cone-beam computed tomography based on a priori case definition of peri-implantitis (≥3mm of radiographic bone loss + inflammatory clinical parameters) Diagnosis of…
- Trial name
- NCT03777449
- Testing
- CBCT
- Where
- Spain
- Volunteers
- 47 people
- Sponsor
- Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain
Peri-implantitis
Long-term Stability of Peri-implantitis Treatments: a 3-year Clinical Evaluation
This prospective study will include patients previously enrolled in the PER-ECL-2019-05 trial who attend the Department of Periodontology (CUO) for maintenance therapy or treatment of periodontal and/or peri-implant diseases…
- Trial name
- NCT07208643
- Where
- 2 sites in Spain
- Volunteers
- 27 people
- Sponsor
- Ramón Pons Calabuig
Dental Implant Failed, Peri-Implantitis
20-year Implant Survival in Periodontally Healthy and Compromised Patients
The aim of this study will be to compare the long-term outcomes of sandblasted and acid-etched (SLA) implants in patients previously treated for periodontitis and in periodontally healthy patients (PHP) after a follow-up of at…
- Conditions
- Dental Implant Failed, Peri-Implantitis, Bone Loss
- Trial name
- NCT04983758
- Testing
- Oral Rehabilitation with dental implants
- Where
- Italy
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Peri-Implantitis, Bone Loss in Jaw
An Evaluation of Salivary Oxidant and Antioxidant Levels in Peri-implant Health and Disease
Objectives: Inflammatory lesions develop in the tissues surrounding implants are referred to as peri-implant diseases. Oxidants, play a role in inflammatory lesions.
- Conditions
- Peri-Implantitis, Bone Loss in Jaw, Dental Implant Failed, Dental Implant Failure Nos
- Trial name
- NCT05724706
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Biruni University
Periodontitis
Antibiotic Study for Dental Implants
This study is for people at least 21 years old who have signs of problems, like swollen gums and shrinking bones, by dental implants.
- Trial name
- NCT00662532
- Testing
- Minocycline HCl
- Where
- 4 sites in United States
- Volunteers
- 44 people
- Sponsor
- OraPharma
Peri-Implantitis and Peri-implant Mucositis
SPiT-frequency I_Peri-implant Mucositis
This is an interventional clinical study on the peri-implant treatment necessary to improve the clinical conditions surrounding dental implants registered with peri-implant inflammation.
- Trial name
- NCT06737328
- Testing
- Submocosal instrumentation using a ultrasonic device (PEEK). Submucosal cleaning
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- University of Oslo
Peri-Implantitis
Assessment of the Accuracy of the Clinical Parameters & Radiographs in Determining the Topography of Implant Bony Lesions
In recent years, dental implants have gained popularity as the treatment choice for replacement of missing teeth. With this, one of the late biological complications that arise is peri-implantitis.
- Trial name
- NCT03698851
- Testing
- Guidor® and Guidor easy-graft® CRYSTAL, Guidor® and Guidor easy-graft® CLASSIC
- Where
- Singapore
- Volunteers
- 4 people
- Sponsor
- National Dental Centre, Singapore
Peri Implant Mucositis, Peri Implantitis
Study on the Treatment of Dental Implants Using the AmbiJet System for Peri-implantitis and Peri-implant Mucositis
Inflammation of the tissue surrounding a dental implant (peri-implantitis or peri-implant mucositis) can lead to implant loss in advanced stages.
- Trial name
- AmbiJet-FIH (NCT07722715)
- Testing
- AmbiJet cold plasma system, Standard Mechanical Debridement (S3 Guideline)
- Where
- Ukraine
- Volunteers
- 26 people
- Sponsor
- Freiburger Medizintechnik GmbH
Postmenopausal Peri-implant Health, Postmenopausal Peri-mucositis
Evaluation of aMMP-8 and IL-1β Levels and Marginal Bone Loss Associated With Peri-Implant Mucositis and Peri-Implantitis in Postmenopausal Women
Peri-implant mucositis and peri-implantitis are among the major biological complications threatening the long-term success of dental implants.
- Conditions
- Postmenopausal Peri-implant Health, Postmenopausal Peri-mucositis, Postmenopausal Peri-implantitis
- Trial name
- NCT07785817
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medipol University
Peri-Implantitis
Patient Perception and Clinical Efficacy of a Collagen Matrix for the Treatment of Peri-implantitis
This is a multi-centre, randomized clinical trial which evaluates the efficiency of the collagen xenograft (Muco-Graft®) in comparison to the autologous connective tissue graft for the augmentation of keratinized mucosa and…
- Trial name
- NCT03551145
- Testing
- Acellular collagen matrix, Autogenous free gingival graft
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Peri-Implant Mucositis, Peri-implantitis
Impact of an AI-Based Chatbot on Implant Patient Management: RCT
Background: Dental implant therapy is a well-established and predictable procedure for replacing missing teeth, with high long-term survival rates.
- Conditions
- Peri-Implant Mucositis, Peri-implantitis, Peri-Implant Health, Peri-implant Inflammation
- Trial name
- NCT07300657
- Testing
- AI Chatbot, Standard Oral Hygiene Education
- Where
- Italy
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Catania
Peri-implant Mucositis, Peri-Implantitis
Dental Implant Care and Oral Hygiene Practices
Objective: This study investigated how patients' knowledge, attitude, and perceptions influence their oral hygiene practices as well as peri-implant health.
- Conditions
- Peri-implant Mucositis, Peri-Implantitis, Dental Plaque
- Trial name
- NCT03497065
- Testing
- non-surgical periodontal treatment
- Where
- Singapore
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- National University Health System, Singapore
Dental Implant Failed, Peri-implant Mucositis
Erythritol vs Ultrasonic Scaler Prophylaxis Systems on Dental Implants With Crowns Made by Different Materials
The aim of the study is to assess which prophylaxis methods is the most suitable for peri-implant hygiene between erythritol and ultrasonic scaler with peek inserts. A randomized clinical trial will be conducted on the patient.
- Conditions
- Dental Implant Failed, Peri-implant Mucositis, Peri-Implantitis
- Trial name
- NCT06288919
- Testing
- Erythritol prophylactic powders, Ultrasonic scaler with peek inserts
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Peri-implantitis
Effect of Smoking on Macrophage-related Chemokines Before and After Non-surgical Treatment of Initial Peri-implantitis
Peri-implantitis is a condition affecting tissues around dental implants, leading to inflammation and bone loss. Smoking is a known risk factor that increases the risk of developing peri-implantitis and reduces treatment success.
- Trial name
- PICF (NCT06810401)
- Testing
- Debridement of implant surface with titanium curettes and irrigation with sterile saline solution
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Buse Naz BÜYÜKAKÇALI ALTAY
Peri-Implantitis
10 Year Follow-up on Reconstructive Bone Procedures for Peri-implantitis
The purpose of this 10 year observational follow-up study was to evaluate the long-term outcomes of reconstructive surgical treatment of peri-implantitis.
- Trial name
- periimpl10y (NCT07678892)
- Testing
- Treatment with a bone graft and a membrane, Treatment with a bone graft
- Where
- Sweden
- Volunteers
- 16 people
- Sponsor
- Kristianstad University
Peri-Implantitis
Surgical Access Combined With Systematically Administered Antibiotics in the Treatment of Peri-implantitis
This randomized clinical trial evaluates the clinical and microbiological (microbial complexes and changes in the diversity of the submucosal biofilm) effects of MTZ+AMX as adjuncts to anti-infectious surgical treatment plus Er…
- Trial name
- NCT05444218
- Testing
- Open flap debridement, Er: YAG irradiation, Metronidazole
- Where
- Brazil
- Volunteers
- 89 people
- Sponsor
- University of Guarulhos
Peri-implantitis
Decontamination Methods in the Treatment of Peri-implantitis
The goal of this clinical study is to compare the effectiveness of different methods for decontaminating dental implant surfaces in the treatment of peri-implantitis.
- Trial name
- NCT07500844
- Testing
- Miramistin, Sodium Bicarbonate Powder, Chlorhexidine
- Where
- Russia
- Volunteers
- 64 people
- Sponsor
- Research Centre for Medical Genetics, Russian Federation
Dental Implant Failed, Prosthesis Failure
Implant-supported Fixed Dental Prostheses (FDPs) With Cantilever Extension
To report the clinical and radiographic outcomes of implant-supported fixed dental prostheses with full-ceramic cantilever extensions (FDPCs) after a function time ≥ 12 months.
- Conditions
- Dental Implant Failed, Prosthesis Failure, Peri-Implantitis
- Trial name
- NCT05676268
- Testing
- Implant-supported fixed dental prostheses with cantilever extension
- Where
- Switzerland
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Bern
Peri-Implantitis, Bone Resorption
Surgical Treatment of Peri-implantitis With Adjunctive Application of Platelet Rich Fibrin (PRF)
Platelet-rich fibrin (PRF) is a second-generation platelet concentrate used for tissue and bone regeneration. PRF releases growth factors such as TGF-β, PDGF, VEGF, IGF, and FGF, which are known to promote wound healing and bone…
- Conditions
- Peri-Implantitis, Bone Resorption, Platelet-Rich Fibrin
- Trial name
- PRF (NCT06679283)
- Testing
- Open flap debridement with a chemo-electric device + PRF, Open flap debridement with a chemo-electric device alone (control)
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Bern