Clinical trials: Peri-Implantation Loss
Periimplantitis, Marginal Bone Loss
A Study of the Crestal Bone Loss Around Bone Level Versus Tissue Level Implants in Non-compliant Patients With Healthy or Reduced Periodontium After 5-8 Years in Function
The goal is to evaluate, after 5 to 8 years, the marginal bone loss around tissue-level implants and bone-level implants in patients who have not followed the maintenance program.
- Trial name
- NCT04942808
- Testing
- Periapical radiographs
- Where
- Lebanon
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Dental Implant Failed
Digital Assessment at Peri-implant Tissues After Immediate Implants With Customized Healing Abutments and Connective Tissue Grafts
After a single-tooth extraction, physiological remodeling processes are unavoidable which leads to a total loss of the periodontal ligament and resorption of the bundle bone.
- Trial name
- NCT05060055
- Testing
- Immediate dental implant placement
- Where
- Portugal
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidade Católica Portuguesa
Dental Implant, Soft Tissue
Effect of Bone-related and Soft-tissue-related Variables on the Marginal Bone Loss of Platform-matched and Platform Switched Dental Implants
In this clinical trial the effect of the implant-abutment morphology (platform-switched vs platform matched) will be assessed in both soft tissue (soft tissue thickness) and hard tissue (marginal bone loss) outcomes.
- Conditions
- Dental Implant, Soft Tissue, Partial-edentulism, Bone Loss
- Trial name
- NCT05670340
- Testing
- Switched Prosthetic Profile, Matched Prosthetic Profile
- Where
- Spain
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Implant Clinical Survival, Restoration Survival
Retrospective Evaluation of Prosthetic Complications and Peri-implant Bone Resorption in Implant-supported Single Unit Fixed Restorations
This study evaluated the one-year outcomes of implant-supported single-tooth fixed restorations used to replace missing teeth. The aim was to assess the success rates of dental implants and identify potential complications during…
- Trial name
- NCT06709508
- Testing
- Examination group
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Özer İşisağ
Tooth Loss in the Anterior Maxilla, Alveolar Bone Loss* / Therapy
Beta-Tricalcium Phosphate Grafting of Peri-implant Jumping Gaps Greater Than 2 mm in Immediate Implants
This randomized controlled trial evaluated whether grafting the peri-implant "jumping gap" with injectable β-tricalcium phosphate (β-TCP) improves outcomes after immediate implant placement in sites where the horizontal gap…
- Trial name
- NCT07709676
- Testing
- Experimental: Test: beta-tricalcium phosphate grafting
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Minia University
Hearing Loss, Cochlear
Electrocochleography Function for Monitoring Residual Hearing
This trial is a pilot study to assess the feasibility of using Electrocochleography recorded from a cochlear implant intra-operatively in real time to monitor the progress of its insertion. Correlation between: 1.
- Trial name
- ECochG (NCT03848338)
- Testing
- Electrocochleography
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Dental Implant, Marginal Bone Loss
Early Bone Loss in Dental Implants
This retrospective observational study aims to evaluate early marginal bone loss around dental implants using panoramic radiographs.
- Trial name
- Early Bone Los (NCT07625813)
- Where
- Turkey (Türkiye)
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Edentulous Jaw, Bone Loss, Alveolar
Effects of Different Centrifuged Platelet Concentrates on Bone Remodelling Around Dental Implants
Platelet concentrates obtained from blood have been used as regenerative biomaterials in periodontal surgery. Along with the migration and proliferation of osteogenic cells, platelets accelerate bone regeneration by increasing…
- Conditions
- Edentulous Jaw, Bone Loss, Alveolar, Resorption, Bone
- Trial name
- NCT04851002
- Testing
- Application of concentrated growth factor with dental implants, Application of advanced platelet rich fibrin with dental implants, Control side of concentrated growth factor study group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Muhammet Atilgan
Peri-implantitis, Alveolar Bone Loss
Diagnostic Accuracy of Large Language Models for Peri-Implant Marginal Bone Loss on Panoramic Radiographs
Dental implants are a routine treatment for missing teeth, but the number of implants affected by peri-implantitis, a progressive inflammatory disease of the tissues around implants, is increasing.
- Conditions
- Peri-implantitis, Alveolar Bone Loss, Dental Implant
- Trial name
- NCT07907900
- Testing
- Multimodal large language model evaluation (ChatGPT, Gemini, Claude, DeepSeek, Grok)
- Where
- Turkey (Türkiye)
- Volunteers
- 784 people, healthy volunteers welcome
- Sponsor
- Ankara University
Completely Edentulous Maxilla, Implant Placement
Peri-Implant Marginal Bone Loss And Implant Stability In Maxillary Implant Overdenture When Using Osseodensification Versus Conventional Drills: A Randomized Clinical Trial
Is to compare between the conventional drills versus osseodensification drills for implant stability and peri-implant marginal bone loss in maxillary implant overdenture.
- Conditions
- Completely Edentulous Maxilla, Implant Placement, Maxillary Implant Overdenture
- Trial name
- NCT05559632
- Testing
- osteotomy for implant placement
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Implant Failed, Marginal Bone Loss
Peri-implant Marginal Bone Loss and Implant Failure in Patients With Smoking Habit
The impact of smoking on dental implant failure has been a constant topic of discussion for the past decade and the current literature confronts the inconclusive evidence of tobacco for a marginal bone loss risk factor.
- Conditions
- Dental Implant Failed, Marginal Bone Loss, Smoking
- Trial name
- NCT05390242
- Testing
- Radiographic study
- Where
- Spain
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Tooth Loss, Tooth Diseases
The Cortical Shield for Facial Bone Reconstruction
To evaluate a novel technique of bone regeneration and simultaneous implant placement in severely damaged sockets.
- Conditions
- Tooth Loss, Tooth Diseases, Tooth Fracture, Tooth Injuries
- Trial name
- NCT04827693
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Verdugo, Fernando, DDS
Teeth Absent, Tooth-loss
Peri-implant Tissues on the Galimplant Anti-rotational Slim Abutment.
A dental implant is an alloplastic material surgically inserted in a residual bone ridge, mainly with a prosthetic foundation. Nowadays the most widely used implants and with a higher degree of scientific evidence are the…
- Conditions
- Teeth Absent, Tooth-loss, Tooth Extraction, Dental Implant
- Trial name
- NCT05118815
- Testing
- Slim abutment, Standard abutment
- Where
- Spain
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Early Pregnancy, Early Pregnancy Loss
EARLY-PREG: A Preconception Cohort Study Based on Counterfactuals to Study Maternal-Embryonic Molecular Interactions
EARLY-PREG is an open-cohort clinical study with a preconception, longitudinal, bidirectional and counterfactual design. The aim of this cohort is to investigate the proteomic signatures of maternal-embryonic communication by…
- Conditions
- Early Pregnancy, Early Pregnancy Loss, Childbirth, Healthy
- Trial name
- EARLY-PREG (NCT07358026)
- Testing
- EMBRYO EXPOSURE
- Where
- Chile
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- MELISA Institute Genomics & Proteomics Research SpA
Jaw, Edentulous, Edentulism, Complete
Tri-Lobe vs. Hexagonal Connections in Immediately Loaded Mandibular Overdentures
Objective: Compare changes in crestal bone height and peri-implant bone density using cone-beam computed tomography (CBCT) at baseline, 6 months, and 12 months post-placement.
- Conditions
- Jaw, Edentulous, Edentulism, Complete, Peri-implant Bone Loss
- Trial name
- NCT07824219
- Testing
- ReActive Implant System (Internal Tri-Lobe Platform), Legacy II Implant System (Internal Hexagonal Platform)
- Where
- United Arab Emirates
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University
Loss of Keratinized Gingiva Around Dental Implants
Efficacy of a Ready Made Plastic Stent With Apically Repositioned Flap in Augmentation of the Peri Implant Soft Tissue
Keratinized gingiva around dental implants are necessary to achieve esthetic appearance in the anterior teeth, also it is more resistant to abrasion, recession, less in plaque accumulation and inflammation, and easy to manipulate…
- Trial name
- NCT03754894
- Testing
- ready made plastic stent application, simple interrupted sutures
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Edentulism, Dental Implantation, Endosseous
Subcrestal vs Juxtacrestal PRAMA Implants With Variable Necks
The goal of this clinical trial is to understand how different implant neck designs and placement depths affect the surrounding bone and peri-implant tissue (the tissue around a dental implant) in adults who need implants in the…
- Conditions
- Edentulism, Dental Implantation, Endosseous, Marginal Bone Loss, Periimplant Bone Loss
- Trial name
- NCT07107464
- Testing
- Short Neck Implant - Crestal Placement, Standard Neck Implant - 1 mm Subcrestal Placement, Long Neck Implant - 2 mm Subcrestal Placement
- Where
- Cuba
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- ARDEC Academy
Bone Loss
Radiographic Evaluation of All-on-4 Implant Prosthesis With Different Materials and Bar Construction Techniques
Eighteen patients will be selected from the outpatient clinic of the Prosthodontic Department, Faculty of Dentistry, Mansoura University seeking prosthetic rehabilitation.
- Trial name
- NCT06071689
- Testing
- screw retained prosthesis
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Dental Implant Placement, Soft Tissue Management in Subcrestal Dental Implants
Implant Placement Depth and Peri-Implant Tissue Outcomes
The primary aim of this randomized clinical trial is to evaluate the influence of subcrestal implant placement depth (-2 mm vs -4 mm) on peri-implant marginal bone level changes, including marginal bone loss and bone remodeling.
- Conditions
- Dental Implant Placement, Soft Tissue Management in Subcrestal Dental Implants, Marginal Bone Loss
- Trial name
- NCT07535528
- Testing
- Subcrestal Implant Placement with Transmucosal Abutment and One Abutment-One Time Protocol
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Dental Implants
Peri-implant Papillary Height Comparison in Microsurgically and Macrosurgically Placed Dental Implants
This study compares the peri-implant soft tissue and crestal bone loss around single implants when placed macrosurgically and microsurgically.
- Trial name
- NCT04189328
- Testing
- dental implant placement using magnifying loupes and microsurgical instruments, macrosurgical dental implant placement
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital