Clinical trials: Peri-Implantitis
Microbial Colonization, Peri-Implantitis
Microbiome Modulation by PEMF on Plaque Induced Mucositis in Human Jaws
To evaluate the impact of Pulsed Electromagnetic Field (PEMF) on mucositis induced in humans around dental implants and correlate these possible effects with the proteomic profile of implants with and without PEMF and teeth.
- Trial name
- NCT07045636
- Testing
- Teeth wih gingivits
- Where
- Brazil
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Jamil awad shibli
Peri-implant Mucositis, Peri-Implantitis
Chitosan Brushes vs Air-Abrasive Devices on Peri-implant Mucositis Treatment: A Randomized Clinical
Bleeding on probing (0,1,2,3), plaque index (+,-) and pocket probing depth will be recorded for each visit. Before the procedure, the patient will be randomly assigned to one of four groups and records will be kept.
- Conditions
- Peri-implant Mucositis, Peri-Implantitis, Bleeding on Probing, Periodontal Pocket
- Trial name
- NCT06287957
- Testing
- Labrida BioClean, EMS Handy 3.0 Perio Premium
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Bleeding, Angiogenesis
The Role of Bleeding at Implant Placement
Angiogenesis is inherently associated to bone formation and healing. During implant osseointegration, a successive and successful angiogenic processes has to occur to promote bone formation. In 1969, Branemark et al.
- Conditions
- Bleeding, Angiogenesis, Peri-Implantitis
- Trial name
- NCT03705247
- Where
- Belgium
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Sensitivity, Peri-implant Mucositis
Sensitivity and Specificity of Peri-Implantitis-Related Parameters
Bleeding on probing demonstrated to have high specificity with certain level of sensitivity to detect periodontal disease. Again, understanding the weak hemidesmosome attachment to the implant surface is imperative to discern on…
- Conditions
- Sensitivity, Peri-implant Mucositis, Peri-Implantational Loss, Peri-Implantitis
- Trial name
- NCT03031392
- Testing
- Sensitivity test
- Where
- Spain
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain
Peri-implantitis
Effect of Enamel Matrix Derivative or Hyaluronic Acid on Non-Surgical Treatment of Peri-Implantitis
The aim of the present randomized controlled clinical study is to compare the clinical, radiographic, and patient-centered efficacy of adjunctive application of either enamel matrix derivative (EMD) or hyaluronic acid (HA) gel in…
- Trial name
- NCT06618560
- Testing
- Enamel Matrix Derivative application, Hyaluronic Acid (HA), Control
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gazi University
Periimplantitis, Dental Plaque
Antimicrobial Activity of Two Mouthwashes
This is a three arm randomized trial. The aim is to evaluate the antimicrobial activity of chlorhexidine and polyhexamethylene biguanide oral antiseptics on the microorganisms of the oral cavity.
- Conditions
- Periimplantitis, Dental Plaque, Periodontal Diseases, Caries
- Trial name
- NCT02375178
- Testing
- chlorhexidine, Polyhexamethylene biguanide, Sterile saline solution
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade do Vale do Sapucai
Peri-Implantitis
Immunological-Clinical Evaluation of the Etiopathogenesis of Peri-Implantitis
A total of 100 adult volunteers of both sexes will be enrolled in the project. The study will be conducted within an international consortium formed for the project, comprising the following institutions: Wroclaw Medical…
- Trial name
- PERI-EDU (NCT07012915)
- Testing
- Blood testing
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Peri-Implantitis, Surgery
Surgical Treatment of Peri-implantitis Using a Bone Substitute With or Without a Resorbable Collagen Membrane
The objective of the present randomized clinical trial will be to compare two surgical methods of treating peri-implantitis. This study will determine if surgical debridement of peri-implantitis bone defects, including air powder…
- Trial name
- NCT05699343
- Testing
- InterOss Collagen (Bone xenograft) and InterOss Collagen Guide (Collagen membrane), InterOss Collagen (Bone xenograft)
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Andrea Ravida
Peri-Implantitis, Peri-implant Mucositis
Effect of Emergence Angle on Peri-implant Status
The study was conducted at the Division of Periodontology, Bolu Abant İzzet Baysal University Faculty of Dentistry. Participants were systemically healthy individuals aged 18 to 70 who had received dental implant prostheses…
- Conditions
- Peri-Implantitis, Peri-implant Mucositis, Peri-implant Health
- Trial name
- EEAPS (NCT07295743)
- Testing
- emergence profile
- Where
- Turkey (Türkiye)
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Peri-Implantitis, Implant Expulsion
Evaluation of the Novel Implant Disease Risk Assessment : a Retrospective Study (IDRA)
Given the novelty of this risk assessment tool, this study will be interested in evaluating its effectiveness through a retrospective approach.
- Trial name
- IDRA (NCT04888572)
- Testing
- Peri-Apical X-ray
- Where
- Lebanon
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Peri-Implantitis
Adjunctive Use of Dermal Matrix to Compensate Dimensional Changes in the Reconstructive Therapy of Peri-implantitis
One critical element regarded to successfully resolve peri-implantitis is to efficiently decontaminate the contaminated implant surface.
- Trial name
- NCT06398288
- Testing
- Dermal matrix (Oracell, LifeNet, USA), No dermal matrix
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain
Peri-Implantitis
The Adjunctive Effect of Soft Tissue Augmentation Procedures of Moderate-severe Peri-implantitis
The key objective of the study is to compare the effects of soft tissue augmentation using a volume stable collagen matrix or autogenous connective tissue graft or no soft tissue augmentation in addition to bone…
- Trial name
- NCT05415111
- Testing
- Subepithelial connective tissue, Volume stable Collagen Matrix, No soft tissue augmentation
- Where
- 3 sites in Germany, Singapore and 1 more
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Nadja Naenni
Periodontitis, Periimplantitis
PPAR, RXR, and VDR Expressions in Peri-implantitis
ABSTRACT Objective: Periodontitis and peri-implantitis are the irreversible destructive diseases of the periodontal and peri-implant tissues.
- Trial name
- NCT04020146
- Testing
- Gingival biopsies
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Peri-implantitis
Effect of Metallic Particles on the Progression of Peri-Implantitis
This observational cross-sectional study aims to investigate the presence and characteristics of metallic micro- and nanoparticles in peri-implant tissues and their potential association with peri-implantitis progression, the…
- Trial name
- NCT07792499
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Alveolar Bone Loss, Peri-Implantitis
Radiological Bone Loss on Different Levels of Dental Implants
One of the criteria used for long-term implant success is the evaluation of radiographic bone loss. It is known that the keratinized mucosa over the alveolar crest forms a protective barrier against inflammatory infiltration.
- Conditions
- Alveolar Bone Loss, Peri-Implantitis, Bone Loss in Jaw
- Trial name
- NCT05595746
- Testing
- dental implant placement
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Peri-Implantitis and Peri-implant Mucositis, Peri-Implantitis and Systemic Inflammation
Longitudinal Evaluation of Regenerative Treatment of Peri-implantitis Assited by Er,Cr:YSGG Laser: up to 10 Years Follow-up
Peri-implantitis is a pathological condition characterized by the inflammation of peri-implant connective tissues and progressive alveolar bone loss.
- Trial name
- Laser (NCT07104760)
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Guarulhos
Peri-Implantitis
Clinical and Biochemical Evaluation of the Efficacy of Non-Surgical Treatment Approaches in the Treatment of Peri-implantitis
Peri-implantitis is a pathological condition associated with plaque that develops around dental implants, characterized by inflammation and progressive bone loss in the peri-implant area.
- Trial name
- NCT05201443
- Testing
- Diode laser, Titanium curettes
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Periodontal Diseases, Periimplant Diseases
Markers of Bone Destruction and Oxidative Stress in Peri-implantitis
The aim of this study is to evaluate and compare the levels of bone resorption (RANKL, OPG) and oxidative stress (Nitrotyrosine, NQO1) markers, along with pro-inflammatory cytokines (IL-1β), in the saliva and peri-implant…
- Trial name
- NCT07397884
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Peri-Implantitis, Peri-implant Mucositis
Lingual Keratinized Tissue in Fully Edentulous Patients and Its Impact on Implant Health
Cross-sectional study involving the measurement of the width of lingual keratinized tissue (in the implant locations) in fully edentulous patients restored with dental implants.
- Conditions
- Peri-Implantitis, Peri-implant Mucositis, Recession, Gingival
- Trial name
- NCT06166017
- Testing
- Exposure to minimal amount of lingual keratinized tissue width
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- George Eastman Dental Hospital, Italy
Periodontal Diseases, Periodontal Pocket
Occlusal Load Distribution and Periodontal Status
Occlusal forces are unevenly distributed among teeth during mastication, potentially predisposing certain teeth to higher functional loads.
- Conditions
- Periodontal Diseases, Periodontal Pocket, Periodontitis, Periimplantitis
- Trial name
- Perio-Occlusio (NCT07199062)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Bari Aldo Moro