Clinical trials: Peri-implantitis
Peri-Implantitis
Reconstructive Surgical Therapy of Peri-implantitis
Various treatment protocols of peri-implantitis involving surgical therapies with open flap debridement procedures, resective or reconstructive modalities have been documented to achieve variable success.
- Trial name
- NCT04769609
- Testing
- bioresorbable membrane
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Gazi University
Implant Complication, Peri-Implantitis
Treatment of Peri-implant Bone Dehiscence Using Autogenous Tooth Plate
The current trial aim was to evaluate clinically and radiographically the changes around dental implants inserted immediately in maxillary anterior esthetic zone using a novel combination of autogenous demineralized tooth graft.
- Conditions
- Implant Complication, Peri-Implantitis, Periodontal Diseases
- Trial name
- NCT06313216
- Testing
- duoteck membrane, autogenous demineralized tooth graft, autogenous demineralized tooth graft and plate
- Where
- Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Periodontitis, Peri-Implantitis
Expression of Inflammasomes in Peri-implantitis and Periodontitis
This is a laboratory-based study and it aims to evaluate the expression of inflammasomes in healthy gingiva and in the presence of peri-implantitis and periodontitis
- Conditions
- Periodontitis, Peri-Implantitis, Inflammation
- Trial name
- NCT05061511
- Testing
- Analysis of inflammasome expression, Histological analysis
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- University of Parma
Peri-Implantitis
Reconstructive Therapy of Peri-implantitis with PDGF-BB (Gem-21)
Peri-implantitis is considered a bacteria-mediated inflammatory disease that leads to a progressive loss of support. During the last decade, research has been striving to understand this entity and strategies for primary and…
- Trial name
- NCT06390124
- Testing
- Platelet Derived Growth Factor (PDGF)
- Where
- Spain
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain
Peri-Implantitis
Peri-implantitis Treatment: Clinical Results of Conventional Treatment vs. the Addition of Biolase
The purpose of the study is to observe the effects of two commonly utilized treatment modalities to treat peri-implantitis and to compare the results.
- Trial name
- NCT03544515
- Testing
- Er,Cr:YSGG laser, Scaling, Inactive Er,Cr:YSGG
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Columbia University
Peri-implantitis
Non-Surgical Treatment of Peri-implantitis with Systemic Azithromycin or Placebo
The primary objective of this study is to evaluate the change in probing depth in patients with peri-implantitis, assessing the influence of systemic antibiotic (azithromycin) adjunctive to non-surgical treatment at 12 months.
- Trial name
- NSTP (NCT06715150)
- Testing
- Azithromcyin
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- University of Santiago de Compostela
Dental Implant Failed, Prosthesis Failure
Implant-supported Fixed Dental Prostheses (FDPs) With Cantilever Extension
To report the clinical and radiographic outcomes of implant-supported fixed dental prostheses with full-ceramic cantilever extensions (FDPCs) after a function time ≥ 12 months.
- Conditions
- Dental Implant Failed, Prosthesis Failure, Peri-Implantitis
- Trial name
- NCT05676268
- Testing
- Implant-supported fixed dental prostheses with cantilever extension
- Where
- Switzerland
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Bern
Peri-Implantitis
Peri-implantitis in HIV-positive Patients
Objectives: This study aimed to assess the prevalence of peri-implantitis in human im-munodeficiency virus (HIV) -positive patients and the presence of a possible correlation between the immunological profile and serological…
- Trial name
- PERIHIV2 (NCT04829968)
- Testing
- gingival conditions control
- Where
- Italy
- Volunteers
- 58 people
- Sponsor
- Università Vita-Salute San Raffaele
Peri-Implantitis
Soft Tissue Assessment in Screw-Retained Maxillary Complete Denture With Electric Welded Framework Versus Casted
comparing the changes in the soft tissue around the implants that will be joined by a metal framework either with electric welding or with the conventional casting method
- Trial name
- NCT04543864
- Testing
- Electric intraoral welding device, casting
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cairo University
Peri-implantitis, Dental Implants
The Effect of Systemic Factors on Peri-implant Health Status and Clinical Indices
This cross-sectional study evaluates the impact of systemic risk factors, including diabetes mellitus, smoking, cardiovascular disease, and osteoporosis, on peri-implant health status and clinical indices.
- Conditions
- Peri-implantitis, Dental Implants, Peri-implant Mucositis
- Trial name
- NCT07530211
- Testing
- Clinical and Radiographic Periodontal Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Inonu University
Peri-implantitis
Timing of Success Evaluation After Flapless Treatment of Peri-Implantitis
Peri-implantitis is an inflammatory disease around dental implants that causes progressive loss of the bone supporting the implant.
- Trial name
- NCT07844642
- Testing
- Flapless non-surgical treatment of peri-implantitis
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- University of Barcelona
Implant Complication, Peri-Implantitis
Prediction of Failure of Dental Implants
The aim of the study is to identify predictors in patient profiles and implant characteristics and to develop and calibrate a prediction model for failure of implants.
- Trial name
- NCT04129957
- Testing
- Placement of dental implants
- Where
- Netherlands
- Volunteers
- 337 people
- Sponsor
- Academic Centre for Dentistry in Amsterdam
Peri-Implantitis
Peri-implantitis - Reconstructive Surgical Therapy
The project will evaluate the potential benefit of the use of bone replacement graft as an adjunct to surgical therapy of peri-implantitis.
- Trial name
- NCT03077061
- Testing
- Open flap debridement, Bone replacement graft
- Where
- Sweden
- Volunteers
- 140 people
- Sponsor
- Göteborg University
Peri-implantitis
The Efficacy and Safety of Chlorhexidine Gluconate Chip (Periochip®) in Therapy of Symptoms in Patients With Peri-implantitis
The purpose of the study is to assess the efficacy and the safety of Chlorhexidine Gluconate chip (Periochip®) versus Placebo Chip in treatment of symptoms in patients with Peri-Implantitis.
- Trial name
- NCT01079663
- Testing
- Chlorhexidine 2.5 mg
- Where
- 2 sites in Israel
- Volunteers
- 60 people
- Sponsor
- Dexcel Pharma Technologies Ltd.
Peri-Implantitis
In Vivo Biofilm Accumulation on Implants With 3 Different Surfaces
A frequent sequela of peri-implantitis itself, but also of its surgery, is the exposure of the implant surface to the oral environment.
- Trial name
- NCT06049121
- Where
- Sweden
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Malmö University
Peri-Implantitis and Peri-implant Mucositis
Occurrence of Peri-Implant Complications: A Multifactorial Cross-Sectional Study
Dental implants have become, over recent decades, one of the most effective and predictable therapeutic options for replacing missing teeth.
- Trial name
- NCT07638969
- Testing
- Dental implant
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain
Peri-Implantitis, Peri-implant Mucositis
Association Between Smoking Habit and Peri-implant Diseases: a Case Control Study
Although smoking has been proposed as well, as a risk factor/indicator for peri-implantitis, there is currently no conclusive evidence. The current literature confronts the inconclusive evidence of tobacco for a risk factor.
- Conditions
- Peri-Implantitis, Peri-implant Mucositis, Bone Loss, Alveolar
- Trial name
- NCT04952428
- Testing
- Re-examination visit ("today visit")
- Where
- Spain
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Peri-Implantitis and Peri-implant Mucositis
Reconstructive Treatment of Peri-implantitis With Electrolytic Decontamination Versus Titanium Brushes
Implants diagnosed with peri-implantitis and amenable for bone reconstructive treatment will be enrolled in the study. The implants will randomly be treated with either an electrolytic or a mechanical cleaning of the implant…
- Trial name
- Galvo vs mech (NCT07814391)
- Testing
- test device GalvoSurge, Mechanical decontamination with titanium brush
- Volunteers
- 38 people
- Sponsor
- George Eastman Dental Hospital, Italy
Peri-implantitis
Electrolytic Surface Decontamination in the Surgical Treatment of Peri-implantitis: A Randomized Clinical Trial
The goal of this clinical trial is to learn whether adjunctive electrolytic surface decontamination can improve the outcomes of surgical treatment of peri-implantitis.
- Trial name
- NCT07644975
- Testing
- Electrolytic Surface Decontamination, Conventional Surgical Treatment
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Istanbul University
Periimplantitis
Application of Local Melatonin in Peri-implantitis
A randomized clinical trial was carried out in patients affected by peri-implantitis with a follow-up of 60 days. Melatonin 1.9 mg or placebo was applied locally to the peri-implant defect after nonsurgical debridement.
- Trial name
- MEL19 (NCT06816277)
- Testing
- Desbridamiento de periimplantitis, Aplicación de melatonina
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Complutense de Madrid