Clinical trials: Perinatal Loss
Major Depressive Disorder
IPT for Major Depression Following Perinatal Loss: Healing After Loss (HeAL)
This study tests the efficacy of interpersonal psychotherapy (IPT) for major depression following perinatal loss (early and late fetal death and early neonatal death) in a sample of 274 women in Flint and Detroit, Michigan.
- Trial name
- HeAL (NCT04629599)
- Testing
- Interpersonal psychotherapy for major depression following perinatal loss, Coping with Depression
- Where
- United States
- Volunteers
- 199 people
- Sponsor
- Michigan State University
Perinatal Loss
The Effect of Mandala Coloring on Perinatal Grief and Psychological Resilience Levels in Women Experiencing Perinatal Loss
The goal of this clinical trial is to evaluate if mandala colouring helps to decrease grief symptoms and increase resilience in women who experienced perinatal loss.
- Trial name
- NCT07060768
- Testing
- Mandala Coloring
- Volunteers
- 60 people
- Sponsor
- University of Yalova
28 Weeks of Gestation, 18 Years and Over
The Effect of Mindfulness-Based Stress Reduction Programme on Stress, Anxiety, Self-Compassion and Prenatal Attachment
This research will be conducted to examine the effects of a mindfulness-based stress reduction (MBSR) programme on stress, anxiety, self-compassion and prenatal attachment in pregnant women with perinatal loss.
- Trial name
- MBSRASPA (NCT06850701)
- Testing
- mbsr
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- 2 sites in United States, Australia
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
COVID-19
Coronavirus Disease 2019 (COVID-19) During Pregnancy: Prevalence of Seroconversion, Effect on Maternal and Perinatal Outcomes and Risk of Vertical Transmission (COVID-MAP)
The objectives of this proposal are to: 1) determine the rate of SARS-CoV-2 seroconversion in unselected pregnant women in Hong Kong; 2) determine the rate of SARS-CoV-2 infection in women presenting with miscarriage and…
- Trial name
- NCT04465474
- Testing
- Non Intervention
- Where
- 10 sites in China, Hong Kong and 1 more
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Perinatal Grief, Perinatal Loss
Comparison of Social Media-Based and Online Training in Grief Counseling Education
This randomized trial aims to compare the effectiveness of two digital educational approaches for perinatal grief counseling training among midwives and nurses working in perinatal care settings in Türkiye: a social media-based…
- Conditions
- Perinatal Grief, Perinatal Loss, Bereavement
- Trial name
- NCT07723170
- Testing
- Social Media-Based Perinatal Grief Counseling Education, Online Perinatal Grief Counseling Education
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Istinye University
ACT, Perinatal Loss
An ACT-Based Family Psychosocial Intervention for Women With Perinatal Loss and Their Spouses: A Pilot Randomised Controlled Trial
This pilot randomised controlled trial evaluates the feasibility, acceptability, and preliminary effects of an Acceptance and Commitment Therapy (ACT)-based family psychosocial intervention for women requiring medically indicated…
- Conditions
- ACT, Perinatal Loss, Mental Health
- Trial name
- NCT07538011
- Testing
- Acceptance and Commitment Therapy
- Where
- 3 sites in China
- Volunteers
- 88 people
- Sponsor
- Second Xiangya Hospital of Central South University
Pregnancy Weight Gain, Eating Disorders
A Single Session Self-guided Acceptance-based Digital Intervention Targeting Food Cravings in Pregnancy
Pregnancy is a time of heightened risk for disordered eating behaviors, which have been linked to adverse health outcomes in gestation, delivery, and the postpartum.
- Conditions
- Pregnancy Weight Gain, Eating Disorders, Perinatal Problems, Binge Eating
- Trial name
- NCT06129461
- Testing
- Single-session acceptance-based online workshop targeting food cravings as predictors of loss of control and binge eating in pregnancy
- Volunteers
- 130 people
- Sponsor
- University at Albany
Perinatal Loss, Grief
Digital Perinatal Bereavement Support Program for Women After Pregnancy Loss
This study aims to evaluate the effectiveness of a digital perinatal bereavement support program designed for women who have experienced pregnancy loss.
- Conditions
- Perinatal Loss, Grief, Depression Anxiety Disorder
- Trial name
- DPBSP (NCT07545551)
- Testing
- Supportive Care
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Gazi University
Cytomegalovirus Congenital, Hearing Loss
Epidemiology of Congenital Cytomegalovirus in a High HIV Prevalence Setting, South Africa
The aim of this project is to determine the epidemiology of congenital cytomegalovirus (CMV) infection and incidence of subsequent permanent neurological sequelae in a high HIV prevalent setting in Soweto, Johannesburg.
- Conditions
- Cytomegalovirus Congenital, Hearing Loss, Neurodevelopmental Disorders, Immunogenicity
- Trial name
- NCT03722615
- Where
- South Africa
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Witwatersrand, South Africa
Miscarriage in First Trimester
Comprehensive Assessment of First Trimester Pregnancy Loss
The FIRST-CARE Study is a prospective research project conducted at Hospital de la Santa Creu i Sant Pau (Barcelona, Spain), aimed at better understanding the causes and consequences of first-trimester pregnancy loss…
- Trial name
- FIRST-CARE (NCT07293819)
- Where
- 2 sites in Spain
- Volunteers
- 225 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Depressive Symptoms, Perinatal Loss
e-Perinatal Butterfly: An Embedded Study for Parents Experiencing Perinatal Loss
This study is part of the e-Perinatal project and is embedded within the parent e-Perinatal cluster randomized controlled trial (NCT07613008). No additional randomization is performed for this embedded study.
- Conditions
- Depressive Symptoms, Perinatal Loss, Perinatal Grief, Anxiety Symptoms
- Trial name
- e-Butterfly (NCT07898176)
- Testing
- e-Perinatal Butterfly, Standard routine maternal care
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Seville
Major Depressive Disorder, Miscarriage
Group Interpersonal Psychotherapy for Treatment of Major Depressive Disorder Following Perinatal Loss
The purpose of this study is to conduct a randomized pilot trial in a sample of 60 women who meet criteria for Major Depressive Disorder (MDD) 1-18 months after a perinatal loss to demonstrate the feasibility of the proposed…
- Conditions
- Major Depressive Disorder, Miscarriage, Stillbirth, Neonatal Death
- Trial name
- NCT01867749
- Testing
- Group Interpersonal Psychotherapy (IPT-G), Coping with Depression (CWD)
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Brown University
Stillbirth and Fetal Death, Miscarriages
Parents' Experience of Child Loss During Pregnancy or Birth
The investigators are conducting a participatory study with and for parents after child loss during pregnancy or birth. Their aim is to develop treatment recommendations for healthcare professional.
- Conditions
- Stillbirth and Fetal Death, Miscarriages, Experience
- Trial name
- NCT06771661
- Testing
- Workshops, Focus group interviews, Narrative interviews
- Where
- Germany
- Volunteers
- 46 people
- Sponsor
- Fritz Sterr
Recurrent Miscarriage, Spontaneous Abortion
Low Plasma Mannose Binding Lectin (p-MBL) Level is a Risk Factor for Recurrent Pregnancy Loss (RPL)
The present study is based on the hypothesis, that recurrent pregnancy loss (RPL) is associated with abnormal plasma mannose binding lectin (p-MBL) level.
- Conditions
- Recurrent Miscarriage, Spontaneous Abortion, Mannose-Binding Lectin Deficiency, Habitual Abortion
- Trial name
- NCT04017754
- Where
- Denmark
- Volunteers
- 452 people
- Sponsor
- Aalborg University Hospital
Simulation-based Learning, Communication Skills
Therapeutic Communication Training in Perinatal Loss: Simulation-Based Approaches
This study aims to evaluate the effect of simulation-based education on nursing students' therapeutic communication skills in managing perinatal loss.
- Conditions
- Simulation-based Learning, Communication Skills, Paper-Pencil Simulation, High-fidelity Simulation
- Trial name
- NCT06959875
- Testing
- High-Fidelity Simulation-Based Therapeutic Communication Training, Paper-Pencil Simulation-Based Therapeutic Communication Training
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Pregnancy Loss, Grief
The Effect of Midwifery Care Given to Couples Experiencing Pregnancy Loss on Grief and General Well-Being
This study was designed as a randomised controlled, 2-group, pre-test-post-test comparative, experimental study to increase the general well-being of women experiencing pregnancy loss and to decrease the level of perinatal grief.
- Conditions
- Pregnancy Loss, Grief, Loss Pregnancy, Care Pattern, Maternal
- Trial name
- NCT06590376
- Testing
- midwifery care based on swanson care theory
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Istanbul University - Cerrahpasa
Perinatal Loss, Perinatal Grief
The Effect of Nursing Care With Peri-Natal Loss
This study was planned to evaluate the effect of standardised nursing care given to women with perinatal loss using the nursing process on perinatal grief, posttraumatic stress and postpartum depression.
- Trial name
- NCT06896214
- Testing
- Standardised nursing care intervention
- Volunteers
- 58 people
- Sponsor
- Gazi University
Pregnancy Loss, Psychological Distress
Effectiveness Web-based Training on Perinatal Loss
The study was conducted in a randomized controlled parallel group experimental design to determine the effect of web-based supportive care provided to women who experienced perinatal loss on perinatal grief, depression…
- Conditions
- Pregnancy Loss, Psychological Distress, Depression
- Trial name
- NCT06605274
- Testing
- Web-Based Education Program, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Abant Izzet Baysal University
Pregnancy Loss, PTSD
Effectiveness of an EMDR Intervention for Perinatal Loss
The investigators objectives is to assess the effectiveness of Eye Movement Desensitization and Reprocessing - recent traumatic episode (EMDR-RTE) as a preventive intervention for Posttraumatic Stress Disorder (PTSD) symptoms…
- Trial name
- NCT05701137
- Testing
- EMDR-RTE, TAU
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Hospital Clinic of Barcelona