Clinical trials: Perinatal Outcomes
Obesity
The Impact of Obesity on Maternal and Perinatal Outcomes
Body Mass Index is an index that is commonly used to classify underweight, overweight and obesity in adults. It is defined as the weight in kilograms divided by the square of the height in meters.The growing epidemic of obesity…
- Trial name
- NCT03251833
- Where
- Egypt
- Volunteers
- 2,000 people
- Sponsor
- Assiut University
Fetal Membranes, Premature Rupture
Perinatal Outcome After Premature Rupture of Membranes
Premature rupture of membranes is an important cause of neonatal morbidity and mortality, mainly because of the complications associated with this pathology (oligohydramnios, cord compression or prolapse, infection).
- Trial name
- NCT01538030
- Where
- Panama
- Volunteers
- 80 people
- Sponsor
- Saint Thomas Hospital, Panama
Immune Response, Birth Weight
Impact of Electronic Cigarettes on Perinatal Immune Responsiveness and Birth Outcomes
There has been a dramatic escalation of electronic cigarette (e-cig) use among women of childbearing age, including pregnant women.
- Conditions
- Immune Response, Birth Weight, Gestational Age
- Trial name
- NCT02553577
- Where
- United States
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- Kristin Ashford
Preeclampsia, Gestational Hypertension
Serum Vasohibin, Cardiotrophin, Endocan & Perinatal Outcomes
Investigation of the relationship between maternal serum vasohibin-1, vasohibin-2, cardiotrophin -1 and endocan concentrations at the 11th and 14th weeks of gestation and adverse perinatal outcomes.
- Conditions
- Preeclampsia, Gestational Hypertension, Gestational Diabetes, Preterm Birth
- Trial name
- NCT06416995
- Testing
- first trimester serum diagnostic test
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Umraniye Education and Research Hospital
Twin Pregnancy
Twins With Specific vs. Traditional Fetal Growth Charts
This study aims to compare how well two different types of fetal growth charts work in tracking the growth of twins during pregnancy. These charts help doctors decide if a fetus is growing normally.
- Trial name
- TWiST (NCT07164001)
- Testing
- Twin-Specific Growth Chart Interpretation, Singleton-Based Growth Chart Interpretation
- Volunteers
- 150 people
- Sponsor
- Indiana University
GDM
Effect of Early Lifestyle Intervention on Perinatal Outcomes in High-risk Women for Gestational Hyperglycemia
This study aims to explore whether early intervention for high-risk groups of gestational hyperglycemia can improve insulin resistance and effectively prevent the occurrence of GDM, and evaluate which pathophysiological subtypes…
- Trial name
- NCT07141173
- Testing
- Individual lifestyle management
- Where
- China
- Volunteers
- 604 people, healthy volunteers welcome
- Sponsor
- Tianjin Central Hospital of Gynecology Obstetrics
Umbilical Cord; Complications, Affecting Fetus
Perinatal Outcomes in Umbilical Cord Entanglement
Umbilical Cord Entanglement and Perinatal Outcomes.
- Trial name
- AssiutU (NCT03504969)
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Assiut University
Low Birth Weight Infants, Preterm Infants
Predictors and Outcomes of Kangaroo Mother Care: A Quasi-Experimental Study in Pakistan
This quasi-experimental study evaluated the impact of Kangaroo Mother Care (KMC) versus Conventional Care (CC) on the growth, developmental milestones, breastfeeding, vaccination, and mortality of low birth weight infants in…
- Trial name
- NCT06559020
- Testing
- Kangroo mother care
- Where
- Pakistan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Perinatal Depression, Parents
Effect of 'Parentbot - a Digital Healthcare Assistant (PDA)' in Improving Parenting Outcomes During the Perinatal Period
The Parentbot - a Digital healthcare Assistant (PDA) is a mobile application-based psychosocial parenting intervention with integrated chatbot features, intended for couples to use during the perinatal period.
- Conditions
- Perinatal Depression, Parents, Self Efficacy, Anxiety
- Trial name
- PDA (NCT05463926)
- Testing
- PDA mobile application
- Where
- Singapore
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Congenital Anomalies, Neonatal Complications
AI-Powered Neonatal Risk Assessment for Improved Perinatal Outcomes
This study aims to develop advanced artificial intelligence (AI) models that predict neonatal risks and complications based on historical multimodal health data, including ultrasound and MRI scans.
- Conditions
- Congenital Anomalies, Neonatal Complications, Perinatal Outcomes, Perinatal Outcomes of the Mother and Fetus
- Trial name
- NCT07064356
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- FetalFirst Limited
Postpartum Depression, Anxiety
Mothers and Babies Qatar (MB-Q): A Postpartum Depression Intervention
Qatar Mothers and Babies is a 4-year collaboration between Northwestern University Feinberg School of Medicine and Sidra Medicine in Doha, Qatar that will generate and evaluate a cultural and contextual adaptation of the Mothers…
- Conditions
- Postpartum Depression, Anxiety, Diabetes
- Trial name
- MB (NCT04442529)
- Testing
- Mothers and Babies (MB)
- Where
- Qatar
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sidra Medicine
Mild Birth Asphyxia, Moderate Birth Asphyxia
Olfactory Testing in Perinatal Asphyxia: Enhancing Risk Assessment
Neonatal asphyxia remains a leading cause of neurodevelopmental disabilities despite advancements in perinatal care. Hypoxic-ischemic encephalopathy (HIE), a severe outcome of asphyxia, impacts 1-3 infants per 1,000 live births…
- Trial name
- MEMOBRAIN (NCT06744244)
- Testing
- Olfactory Testing, Heart rate (HR), Heart Rate Variability (HRV), Respiratory Rate (RR), peripheral oxygen saturation (SpO2), Video-EEG
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Parma
Sickle Cell Disease, Pregnancy, High Risk
TAPS2 Transfusion Antenatally in Pregnant Women With SCD
Sickle Cell Disease (SCD) is a serious inherited blood disorder affecting red blood cells. When oxygen levels drop the red cells become abnormally shaped and unable to move through the blood vessels easily.
- Conditions
- Sickle Cell Disease, Pregnancy, High Risk, Blood Transfusion Complication
- Trial name
- TAPS2 (NCT03975894)
- Testing
- Serial prophylactic exchange blood transfusion (SPEBT).
- Where
- 6 sites in United Kingdom
- Volunteers
- 50 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Pregnancy, Post Partum
Deconstructing Maternal Burdens: Doulas and the Community Unite for Health
This study is a randomized controlled trial comparing two models of doula support for pregnant individuals enrolled in Medicaid: an enhanced doula support model, in which support starts earlier in pregnancy, occurs more…
- Conditions
- Pregnancy, Post Partum, Doula Care, Postpartum Depression (PPD)
- Trial name
- UNITE (NCT07799805)
- Testing
- Doula, Standard (non-enhanced) Medicaid doula support
- Where
- United States
- Volunteers
- 516 people
- Sponsor
- University of Florida
Uterine Rupture, Mode of Delivery
Uterine Rupture During Labor Among Women With a Prior Cesarean Delivery
Although a rare event, uterine rupture during labour is one of the most serious obstetric complications because of the dramatic maternal-fetal consequences that can result.
- Trial name
- NCT04566705
- Testing
- Risks factors, maternal and neonatal outcomes/complications
- Where
- France
- Volunteers
- 95 people
- Sponsor
- University Hospital, Montpellier
Preeclampsia
Randomizated Open-label Control Trial to Evaluate if the Incorporation of sFlt1/PlGF Ratio in the Diagnosis and Classification of PE Improves Maternal and Perinatal Outcomes in Women With the Suspicion of the Disease
Preeclampsia is a leading cause of maternal and neonatal morbidity and mortality worldwide. The morbidity and mortality of this condition arises from two main causes: 1) the lack of specific and sensible methods for its diagnosis…
- Trial name
- EuroPE (NCT03231657)
- Testing
- Placental biomarkers
- Where
- Spain
- Volunteers
- 2,536 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Perinatal Mental Health, Pregnancy Related
Mindfulness-Based Stress Reduction for Psycho-socially Vulnerable Pregnant Women.
The aim of the study is to address the need for a wider array of evidence-based and non-pharmacological options to improve mental health in a psycho-socially highly vulnerable group of pregnant women.
- Trial name
- NCT05300646
- Testing
- Prenatal mindfulness-based stress reduction
- Where
- 2 sites in Denmark
- Volunteers
- 238 people
- Sponsor
- University of Aarhus
Diabetes, Gestational
Effects of an Aquatic Physical Exercise Program on Glycaemic Control and Perinatal Outcomes of Gestational Diabetes: Study Protocol for a Randomized Controlled Trial
The purpose of this study is to verify the efficacy of an aquatic physical exercise program on GDM control and adverse maternal and fetal outcomes.
- Trial name
- NCT01940003
- Testing
- Aquatic exercise
- Where
- Brazil
- Volunteers
- 72 people
- Sponsor
- Professor Fernando Figueira Integral Medicine Institute
Endometriosis
Perinatal Consequences of Endometriosis
Endometriosis is a benign gynecological disease, characterized by the presence of endometrium-like tissue outside the uterine cavity that affect up to 10-15% of women in reproductive age worldwide, with an extensive impact on…
- Trial name
- ENDOBST (NCT02498691)
- Testing
- Biological collection
- Where
- France
- Volunteers
- 1,444 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Maternity Continuum of Care, Obstetric Health Literacy
Effect of Mobile Health Integrated Antenatal Care Intervention
The World Health Organization (WHO) has released wide-ranging guidelines on antenatal care (ANC) with the aiming to provide ongoing maternity care and "positive pregnancy experience".
- Conditions
- Maternity Continuum of Care, Obstetric Health Literacy, Maternal Outcomes, Perinatal Outcomes
- Trial name
- NCT07130890
- Testing
- Health for All Mobile health application
- Where
- Ethiopia
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Yibelu Bazezew Bitewa