Clinical trials: Perineal Injury
Perineal Tear Resulting From Childbirth
Perineal Massage and Warm Compresses - RCT for Reduce Perineal Trauma During Labor
The aim of this study is to evaluate the effect of a combined perineal massage and warm compresses intervention on the perineum integrity during second stage of labor.
- Trial name
- PeMWaC (NCT05854888)
- Testing
- Perineal Massage and Warm Compresses (PeMWaC), Control Group (Hands-on)
- Where
- Portugal
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Hemorrhage of Cesarean Section and/or Perineal Wound
Efficacy of Tranexamic Acid in Reducing Blood Loss During and After Caesarean Section
The aim of this study is to evaluate the efficacy of tranexamic acid in reducing blood loss during and after elective C.S. The Research Question Is Tranexamic acid effective in reducing blood loss during and after elective…
- Trial name
- NCT02350179
- Testing
- Tranexamic Acid, Glucose
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Perineum; Rupture, Perineum; Tear
In Vivo Evaluation of Perineal Mechanical Properties During Childbirth
The objective of this work is to evaluate perineal elasticity and deformation and the perineal stresses induced by the fetus during delivery.
- Conditions
- Perineum; Rupture, Perineum; Tear, Perineal Tear
- Trial name
- MecaPer (NCT05556304)
- Testing
- assessment in the 8th month of pregnancy and during delivery
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Tear, Pelvic Organ, Obstetric Trauma
A Pilot Study To Evaluate The Preliminary Safety And Feasibility Of The Materna Medical Device
The Materna device aims to prevent pelvic tissue damage by preventing overstretching of pelvic floor muscle fibers during delivery.
- Trial name
- NCT02332759
- Testing
- Materna Medical
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Vaginal Discharge, Perineum; Rupture
Efficacy and Safety of the Application of Local Anaesthetic in Spray to Repair of 1st- 2nd Perineal Lacerations
Randomized controlled trial aimed at evaluating the efficacy and safety of the use of a local anesthetic spray, commonly used in clinical practice as off-label, during the suturing of perineal lacerations in post-partum…
- Conditions
- Vaginal Discharge, Perineum; Rupture, Analgesia
- Trial name
- LISPRAY (NCT05201313)
- Testing
- Lidocaine Hydrochloride, Mepivacaine Injection
- Where
- Italy
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Azienda Sanitaria-Universitaria Integrata di Udine
Perineal Injury
The Use of St. John's Wort Oil With Massage in the Perineum During Childbirth
Perineal trauma, whether spontaneous or episiotomy, is a condition that affects the quality of life in primiparous women . In women who have experienced perineal trauma, problems such as dyspareunia, urinary and fecal…
- Trial name
- NCT05164926
- Testing
- perineal massage with St. John's Wort oil
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Perineum; Tear
Use of Warm Compresses During the Second Stage and the Risk of Perineal Tears
There is a controversy regarding whether warm compresses influence the rate of intact perineum after a vaginal delivery. According to a meta-analysis published in 2019 that included 7 randomized prospective trials, approximately…
- Trial name
- NCT05851170
- Testing
- The use of warm compresses and almond oil on the perineum during second stage, Use of almond oil use (routine care) during second stage
- Where
- Israel
- Volunteers
- 412 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Neuralgia, Perineal
Promoting Optimal Healing After Laceration Repair Study
The goal of this research is to investigate three different methods of perineal skin closure during second-degree perineal wound repair and determine which method is associated with the least amount of patient pain.
- Trial name
- PALS (NCT02055794)
- Testing
- Suturing of the perineal skin, Closing perineal skin with surgical glue, No suturing of the perineal skin
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Episiotomy Wound
Comparison Between Lidocaine Prilocaine Cream and Lidocaine Injection on Pain Control During Episiotomy.
The present study aims to compare the effects of lidocaine-prilocaine cream and lidocaine injection on the reduction of pain while doing and repairing episiotomy, controlling the pain in the post-partum period, and reduction the…
- Trial name
- NCT05891132
- Testing
- 10 ml of lidocaine 2%, lidocaine prilocaine cream 15gm
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Perineal Trauma, Ritgen Maneuver
Ritgen Maneuver and Birth-Related Perineal Trauma: RCT
Perineal trauma is one of the common complications that may occur during the second stage of labor and can negatively affect women's postpartum recovery and quality of life.
- Trial name
- NCT07713173
- Testing
- Ritgen maneuver, Routine Care Group
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Medipol University
Heat Therapy, Perineal Tear
The Effect of Using Perineal Warm Compress Techniques During the Second Stage of Labor on Perineal Outcomes
The goal of the clinical trial is to determine the effect of second-stage warm compress application on perineal pain and trauma among primiparous women.
- Conditions
- Heat Therapy, Perineal Tear, Pain, Labor
- Trial name
- NCT05955352
- Testing
- Perineal warm compression Technique
- Where
- Nepal
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Tribhuvan University, Nepal
Episiotomy; Complications, Laceration
Comparison Low-Level Laser Therapy With Cryotherapy in Parturients With Laceration and/or Episiotomy on Pain Reduction
The changes that occur during pregnancy can lead to symptoms and complaints for women. Vaginal delivery has several benefits for both the mother and baby; however, during labor, some injuries may occur, such as lacerations and…
- Trial name
- CL (NCT06370910)
- Testing
- Low-Level Laser Therapy
- Where
- Brazil
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Perineal Pain, Birth Satisfaction
The Effect of Birth Ball and Perineal Massage on Perineal Pain, Perineal Trauma and Birth Satisfaction
One of the important causes of perineal trauma is perineal tension. By reducing this tension, perineal trauma can be prevented. Perineal trauma is a birth complication that can be prevented with midwifery approaches.
- Conditions
- Perineal Pain, Birth Satisfaction, Perineal Laceration, Tear, or Rupture During Delivery
- Trial name
- NCT06935643
- Testing
- Birth Ball, Perineal Massage, Control Group
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Perineal Injury, Perineal Laceration, Tear, or Rupture During Delivery
Targeted Deep Pelvic Floor Muscle Physiotherapy Versus Antenatal Perineal Massage in Nulliparous Women
This prospective randomized clinical trial evaluates whether targeted deep pelvic floor muscle physiotherapy is more effective than standard antenatal perineal massage in reducing perineal trauma among nulliparous women.
- Trial name
- NCT07764068
- Testing
- Targeted Deep Pelvic Floor Muscle Physiotherapy, Standard Antenatal Perineal Massage
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Pregnancy, Perineum; Injury
Pilates and the Pelvic Floor: A Quasi-experimental Study
In this paper, it is postulates that in pregnant women, the practice of PM led by a qualified professional for a period of four weeks can reduce the incidence of pelvic floor dysfunction (PFD) by decreasing the number of birth…
- Conditions
- Pregnancy, Perineum; Injury, Pilates Method, Episiotomy Wound
- Trial name
- NCT04431102
- Testing
- PILATES METHOD
- Where
- Spain
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Huelva
Perineal Injury, Pain
Epsom Salt Compresses to Relieve Perineal for Postpartum Care: a Clinical Trial
The goal of this clinical trial is to determine if topical application of compresses soaked in 25% magnesium sulfate on painful perineum after birth is effective to alleviate pain.
- Trial name
- NCT06393608
- Testing
- Epsom salt, Water
- Where
- 4 sites in Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Antoine Roger
Obstetric Anal Sphincter Injury, Severe Perineal Trauma
CArE for OAsI Study: Care Pathways and Anorectal Evaluation for OASI Associated Incontinence
The aim of this study is to ascertain which pathways currently exist in relation to the follow up of patients with obstetric anal sphincter injury related incontinence.
- Conditions
- Obstetric Anal Sphincter Injury, Severe Perineal Trauma, Grade 3 Perineal Tear, Grade 4 Perineal Tear
- Trial name
- CArE for OAsI (NCT06143072)
- Where
- United Kingdom
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- London North West Healthcare NHS Trust
Perineal Tear, Episiotomy Wound
Continuous Versus Discontinuous Suture in the Perineals Lesions
The hypothesis: Women who have a continuous suture have better health outcomes Two types of sutures were placed in the perineal lesion, using different techniques.
- Trial name
- NCT03825211
- Testing
- Continuous suture in the perineals lesions, Discontinuous suture in the perineals lesions
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- University of Jaén
Birth Trauma
Video Analysis of Vaginal Deliveries
Video documentation of vaginal deliveries to evaluate the impact of the support of the perineum
- Trial name
- NCT02295904
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Hemorrhage of Cesarean Section and/or Perineal Wound, Postpartum Hemorrhage
Role of Tranexamic Acid Versus Uterine Cooling at Caesarean Section
This study aims to compare role of a prophylactic predefined intravenous Tranexamic Acid dose versus intraoperative Uterine Cooling in reducing blood loss and incidence of postpartum hemorrhage at secondary CS.
- Conditions
- Hemorrhage of Cesarean Section and/or Perineal Wound, Postpartum Hemorrhage, Uterine Atony
- Trial name
- NCT02780245
- Testing
- Tranexamic Acid, Intraoperative Uterine Cooling
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Talkha Central Hospital