Clinical trials: Perineal Pain
Neuropathic Pain, Nociplastic Pain
Evolution of Different Sensitivity Levels in Patients With Chronic Neuropathic Pain in the Pelvi-perineal Region After Treatment With High-concentration Capsaicin Patches
The primary objective of this study will be to demonstrate a change in pain sensitization parameters before and after the application of the high-concentration capsaicin patch.
- Trial name
- CAPSASENS (NCT07660510)
- Testing
- Quantitative Sensory Testing and questionnaires
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Nantes University Hospital
Pain
Epidural Morphine Following Vaginal Delivery
The investigators believe that pain management following a vaginal delivery can be improved. Many women receive epidural medication during labor and delivery, and the investigators felt that using the epidural following delivery…
- Trial name
- NCT00803114
- Testing
- Preservative-free epidural morphine
- Where
- Canada
- Volunteers
- 228 people
- Sponsor
- Mount Sinai Hospital, Canada
Myofascial Pelviperineal Pain
Multicenter Randomized Double-blind Study Evaluating the Effects of Botulinum Toxin A Associated With ropivacaïne Versus ropivacaïne Alone in the Treatment of the Myofascial Pelviperineal Pain
Myofascial pains are frequently found during the clinical examination of the patients presenting a painful chronic syndrome of the pelvis or the perineum.
- Trial name
- MYOTOX (NCT01967524)
- Testing
- botulinum toxin A + ropivacaïne, Ropivacaïne
- Where
- 6 sites in France
- Volunteers
- 80 people
- Sponsor
- Nantes University Hospital
Episiotomy, Lacerations Perineal
Physiotherapeutic Protocol Compared to Usual Care in the Treatment of Primiparas After Perineal Trauma
The aim of this study is to assess the effectiveness of a pelvic floor muscle training (PFMT) protocol associated with cryotherapy initiated in the immediate postpartum period in relieving pain in primiparous women who suffered…
- Conditions
- Episiotomy, Lacerations Perineal, Obstetric Anal Sphincter Injury, Perineal Injury
- Trial name
- MPR (NCT07170007)
- Testing
- Physiotherapeutic protocol, Usual maternity care
- Where
- Brazil
- Volunteers
- 82 people
- Sponsor
- University of Sao Paulo
Prolapse, Vaginal, Stress Urinary Incontinence
Perineal Massage for Pessary Examinations
Pessaries are effective non-surgical devices for reduction of prolapse. However, use of pessaries are limited in some women due to patient discomfort.
- Conditions
- Prolapse, Vaginal, Stress Urinary Incontinence, Pessaries, Pain
- Trial name
- NCT06416982
- Testing
- Perineal massage
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of North Carolina, Chapel Hill
Perineal Injury, Pain
Epsom Salt Compresses to Relieve Perineal for Postpartum Care: a Clinical Trial
The goal of this clinical trial is to determine if topical application of compresses soaked in 25% magnesium sulfate on painful perineum after birth is effective to alleviate pain.
- Trial name
- NCT06393608
- Testing
- Epsom salt, Water
- Where
- 4 sites in Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Antoine Roger
Pelvic Floor Dysfunction, Perineal Laceration
Perineal Protection Device for Reducing Perineal Trauma During Vaginal Delivery in First-time Mothers: a Multicenter Randomized Controlled Trial
The goal of this clinical trial is to determine whether using a soft perineal protection device (BabySlide®) in addition to standard manual perineal support during vaginal delivery can reduce the risk of perineal trauma in…
- Conditions
- Pelvic Floor Dysfunction, Perineal Laceration, Wound Dehiscence, Anal Incontinence
- Trial name
- PeriPROTECT (NCT07862660)
- Testing
- Perineal protection device, BabySlide, Standard manual perineal support
- Where
- Sweden
- Volunteers
- 4,226 people
- Sponsor
- Region Skane
Interactable Malignant Perineal Pain
Thermal Radiofrequency Versus Neurolytic Saddle Rhizotomyfor Severe Pereneal Cancer Pain
The control of perineal malignant pain is difficult and challenging for pain physicians. Different modalities have been tried to treat this complex pain syndrome including pharmacotherapy and interventional therapy.
- Trial name
- NCT03084575
- Testing
- Thermal radio Frequency, selective (unilateral S3, bilateral S4 and S5) saddle rhizotomy, hyperbaric chemical saddle Rhizotomy (6 % pherol in glycerin), Thermal RF lesioning is done using Bailys RF generator
- Volunteers
- 40 people
- Sponsor
- Cairo University
Perineal Pain
Suturing Techniques on Perineal Pain
Perineorrhaphy, sometimes referred to as perineoplasty, is a common procedure in pelvic reconstructive surgery that entails surgical repair of the perineum.
- Trial name
- PNO (NCT05264194)
- Testing
- Suturing technique
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Oklahoma
Delivery Problem, Childrearing
Perineal Massage Performed During the Labour
In this study, perineal massage was applied to primiparous women who did not give birth before, as a quasi-experimental control group to determine the effects of massage on birth comfort, perineal trauma and perineal pain.
- Conditions
- Delivery Problem, Childrearing, Satisfaction, Patient, Perineum; Injury
- Trial name
- NCT05962918
- Testing
- Perinal massage
- Where
- Turkey (Türkiye)
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Munzur University
Heat Therapy, Perineal Tear
The Effect of Using Perineal Warm Compress Techniques During the Second Stage of Labor on Perineal Outcomes
The goal of the clinical trial is to determine the effect of second-stage warm compress application on perineal pain and trauma among primiparous women.
- Conditions
- Heat Therapy, Perineal Tear, Pain, Labor
- Trial name
- NCT05955352
- Testing
- Perineal warm compression Technique
- Where
- Nepal
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Tribhuvan University, Nepal
Lignocaine, Bupivacaine
Lignocaine vs Bupivacaine Infiltration for Postpartum Perineal Pain After Vaginal Delivery With Episiotomy in Primigravidae
In this study, we will compare the effect and safety of lignocaine versus bupivacaine infiltration for postpartum perineal pain after vaginal delivery with episiotomy in primigravidae.
- Conditions
- Lignocaine, Bupivacaine, Postpartum Perineal Pain, Vaginal Delivery
- Trial name
- NCT06568289
- Testing
- Lignocaine, Bupivacaine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Episiotomy
Effect of Levobupivacaine Infiltration on the Post Partum Perineal Pain in Episiotomy, in Primiparous Women After Instrumental Delivery
An episiotomy is an incision of the perineum to facilitate childbirth by natural means. Perineal pain are more frequent and intense if the incision of the perineum is important.
- Trial name
- NCT02796547
- Testing
- Levobupivacaine, Physiological serum
- Where
- 2 sites in Belgium, France
- Sponsor
- Brugmann University Hospital
Second Degree Perineal Tear During Delivery - Delivered, Episiotomy; Complications
Perineal Local Infiltration Study
The prevalence of birth canal lacerations is more than 70% of all deliveries in Canada. The repair of such lacerations is usually done using a pre-existing epidural analgesia.
- Conditions
- Second Degree Perineal Tear During Delivery - Delivered, Episiotomy; Complications, Anesthesia, Local
- Trial name
- PLIS (NCT03672500)
- Testing
- Bupivacaine 0.5%+Epinephrine 50mc
- Where
- Canada
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Post-partum Perineal Pain, Episiotomy
Post-partum Perineal Pain - Chirocaine®
The aim of this placebo-controlled clinical trial is to assess the effectiveness of the local infiltration of the analgesic Chirocaïne® on perineal pain after episiotomy or first-degree tear.
- Conditions
- Post-partum Perineal Pain, Episiotomy, Vaginal Tear
- Trial name
- EPISIO (NCT02905695)
- Testing
- Chirocaine
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Hopital Foch
Dyspareunia
Effect of Radiofrequency in the Treatment of de Novo Dyspareunia at 4 to 12 Months Postpartum.
This study evaluates if the application of resistive capacitive monopolar radiofrequency therapy associated with Thiele massage is effective when treating de novo dyspareunia at 4 to 12 months postpartum.
- Trial name
- NCT05417334
- Testing
- Resistive Capicitive Monopolar Radiofrequency
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Hospital Clinic of Barcelona
Perineal Scars, Delivery Complication
MILTA vs Placebo Use Comparison for the Management of Pain Related to Perineal Scars Following Delivery
The incidence of perineal scars after a pregnancy is high, either related to an episiotomy or to spontaneous perineal tears. These perineal scars can result in acute pain but also in chronic pain for some women.
- Conditions
- Perineal Scars, Delivery Complication, Episiotomy, Pain
- Trial name
- MILTADoIP (NCT05345600)
- Testing
- MILTA probe
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Cancer Pain, Neck Cancer
Perineal Massage in Women With Gynecological Cancer
The high incidence of gynecological cancers, together with dyspareunia and vaginal stenosis, some of its most frequent sequelae, create the need to continue studying and researching oncological physiotherapy techniques that treat…
- Trial name
- NCT06432998
- Testing
- Perineal massage, Standard treatment
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- University of Alcala
Labor Pain
The Effect of the Multifunctional Birthing Ball on Labor Pain
Objective: By using the newly designed multifunctional birthing ball, it is aimed to reduce the intense perineal and sacral pain in the first and second stages of labor, to prevent perineal tears, pain and episiotomy opening with…
- Trial name
- NCT06229808
- Testing
- Multifunctional Birthing ball
- Where
- Cyprus
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Near East University, Turkey
Labor Pain, Perineal Pain
The Effect of LI4 Acupressure on Perineal Pain and Postpartum Comfort During Episiotomy Repair
The study was planned to evaluate the effect of LI4 acupressure application on perineal pain and postpartum comfort during episiotomy repair.
- Conditions
- Labor Pain, Perineal Pain, Postpartum Comfort
- Trial name
- NCT06407505
- Testing
- Acupressure group
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Uskudar University