Clinical trials: Perineal Pain
Perineal Tear
The Effect of Neuraxial Morphine (Duramorph) on Pain Control
With the rise of the opioid epidemic, it is important for physicians to be more mindful of the amount of narcotic prescriptions that are being written every day.
- Trial name
- NCT03926559
- Testing
- Morphine.
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Augusta University
Post-Vaginal Delivery Perineal Pain
Oral vs Rectal Admin of Naproxen for Post-Vag Perineal Pain Control
The primary objective of this study is to determine whether the route of administration of naproxen (either by mouth or rectally) influences post-vaginal delivery perineal pain control.
- Trial name
- NCT00222976
- Testing
- Naproxen
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Women After Delivery With Perineal Pain
Comparison Between Pads With Cold Solution of Magnesium Sulfate or Cold Water Postpartum Perineal Pain and Healing
Perineal pain after delivery is common and is caused by local bruising or episiotomy. The pain may last for several days or months. Thus, several analgesic methods are offered.
- Trial name
- NCT04464005
- Testing
- Magnesium sulfate 33% solution, Cold water
- Where
- Israel
- Volunteers
- 131 people
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Dyspareunia, Pelvic Pain
Electrolysis Technique vs Manual Therapy in Pelvic Pain
Pelvic floor muscle physical therapy is recommended in clinical guidelines for women dyspareunia and pelvic pain. This study compare pelvic floor manual therapy and intratissue percutaneous electrolysis (EPI) technique in the…
- Conditions
- Dyspareunia, Pelvic Pain, Pelvic Floor Disorders, Musculoskeletal Pain
- Trial name
- NCT03163160
- Testing
- Pelvic floor manual therapy group, Pelvic floor electrolysis group
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Quirón Madrid University Hospital
Pain
Nonpharmacological Method for Relief of Episiotomy
The study is a randomized controlled study to evaluate the effectiveness of acupressure applied to primiparous pregnant women who underwent episiotomy in the early postpartum period.
- Trial name
- NCT05649124
- Testing
- Acupressure group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Perineal Tear
Skin Glues Compared to Running Sutures for Perineal Skin Repair After Vaginal Delivery. A Randomized Controlled Trial
The incidence of a perineal tears during labor is 70 to 90%, while in 96% of the cases it's a minor perineal tear (grade 1). In about 3% to 4% the perineal tear is major and involve the external (grade 3) and the internal anal…
- Trial name
- NCT03983343
- Testing
- exofin®
- Where
- Israel
- Volunteers
- 182 people
- Sponsor
- HaEmek Medical Center, Israel
Pain, Perineal Healing
Low-level Laser Therapy in Pain and Perineal Healing in the Immediate Postpartum Period: a Randomized Clinical Trial.
This randomized clinical trial aims to evaluate the effectiveness of low-level laser therapy compared with sham treatment on pain intensity and perineal wound healing quality in the immediate postpartum period.
- Trial name
- LaserPerineal (NCT07480083)
- Testing
- low-level laser therapy
- Where
- Brazil
- Volunteers
- 206 people
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Chronic Pelvic Pain, Chronic Perineal Pain
Neurophysiological Validation of the Clinical Criteria of Sensitization in Chronic Pelvic and Perineal Pain Population
The purpose of this study is to assess and validate the clinical criteria of sensitization ("Convergences PP criteria") selected by the expert consensus with neurophysiological sensory testing.
- Trial name
- DOPEC (NCT03541954)
- Testing
- Sensory testing of lower urinary tract., Sensory testing of lower rectal tract, Sensory testing of vulva muscles
- Where
- 2 sites in France
- Volunteers
- 60 people
- Sponsor
- Nantes University Hospital
Primipara Pregnant, Primipara Labour
The Effect of Birth Positions on Labor
This study is a randomized controlled trial aimed at evaluating the effects of positions used during labor on pelvic floor muscle strength and the severity and nature of perineal pain in primiparous pregnant women.
- Trial name
- NCT07243522
- Testing
- Semi-sitting birth position
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ege University
Pain, Postpartum Depression
Postpartum Perineal Pain After Obstetric Anal Sphincter Injuries
Obstetric anal sphincter injuries (OASIS) encompass both third and fourth degree perineal tears. These tears can have a significant impact on women's quality of life in the short and long term.
- Trial name
- NCT03470675
- Testing
- Epidural saline + IV saline, Epidural morphine 3 mg + IV saline, Epidural morphine 3 mg + IV ketamine 0.3 mg/kg
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Northwestern University
Proctalgia
Analgesic Effect of an Injection of Botulinum Toxin Type A in the Ganglion Impar in Patients With Chronic Proctalgia
The main objective is to evaluate the analgesic efficacy of botulinum toxin type A in refractory chronic proctalgia one month after a bilateral injection of 50 units of Botox ® in the ganglion Impar (total dose = 100 units)
- Trial name
- Impartox (NCT01331356)
- Testing
- Botox
- Where
- 2 sites in France
- Volunteers
- 18 people
- Sponsor
- Nantes University Hospital
Pain, Patient Satisfaction
Patient-controlled Sedation During Repair of Obstetric Perineal Lacerations
The PROP(ofol)-study (EU CT number: 2022-502292-39-00, protocol number: ) is a clinical trial phase IV single centre prospective randomized controlled trial with parallel groups.
- Trial name
- NCT06044103
- Testing
- PDB + PCS
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Marie Blomberg
Episiotomy
Effect of Foot Reflexology on Perineal Pain, Fatigue and Healing Quality in Primiparous Patients Undergoing Episiotomy
The act of giving birth can expose women to many risks during pregnancy and the birth process. It causes long-term emotional problems in pregnant women who experience labor pain and negatively affects their mental health.
- Trial name
- NCT06955507
- Testing
- reflexology
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Perineal Tear
Effectiveness of Warm Packs, Perineal Massage and Hands Off During Labour in the Perineal Outcomes.
This study evaluates the effectiveness of warm packs, perineal massage and hands off, during labour, in the perineal outcomes. The perineal outcomes are perineal tears, grade of perineal tears, need of suture, perineal edema…
- Trial name
- NCT02588508
- Testing
- Warm packs, Perineal massage
- Where
- Brazil
- Volunteers
- 201 people
- Sponsor
- Universidade Federal de Pernambuco
Maternal Pushing Techniques, Perineal Trauma
Vocalization and Spontaneous Pushing in the Second Stage of Labor
The second stage of labor, defined as the period from full cervical dilatation to fetal birth, is a critical phase in which maternal pushing techniques may significantly affect maternal and neonatal outcomes (1-5).
- Conditions
- Maternal Pushing Techniques, Perineal Trauma, Maternal Fatigue, Labor
- Trial name
- NCT07316348
- Testing
- The vocalization straining technique will be used.
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Episiotomy Wound
Relaxation Exercise With Virtual Reality Glasses and Episiotomy-induces Perineal Pain and Fear
The aim of this clinical study is to compare the pain and fear scores of women who gave birth for the first time and who did and did not do relaxation exercises with virtual reality glasses during episiotomy incision and…
- Trial name
- NCT05955716
- Testing
- Virtual reality glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Özlem Çiçek
Postpartum Perineal Pain
Strategy of Micronutrient Management in Parturient and Layered Women With a Dietary Supplement Rich in Porphyra HSP®
The aim of the study is to evaluate in primiparous patients the benefit of supplementation with Proteochoc® to reduce perineal pain in the postpartum especially, in sitting posture.
- Trial name
- NCT02967796
- Testing
- Proteochoc
- Where
- France
- Volunteers
- 60 people
- Sponsor
- PiLeJe