Clinical trials: Perineum; Injury
Perineal Injury, Pain Vulva
Improving Postoperative Recovery: A Study of Multimodal Perineal Analgesia Protocol (MPAP) After Vaginal Surgery
The purpose of this research is to determine if using perineal ice packs, medicated witch-hazel pads (MAJOR® Medi-Pads), and topical benzocaine spray (Dermoplast®) helps reduce perineal pain after perineorrhaphy and/or posterior…
- Conditions
- Perineal Injury, Pain Vulva, Perineum; Injury
- Trial name
- NCT07401134
- Testing
- Perineal ice packs, medicated witch-hazel pads, and topical benzocaine spray
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Miami
Obstetric Trauma, Perineum; Injury
The Effect of Perineal Wound Infection on the Anal Sphincter
Perineal injury following childbirth can result in complications such as wound infection. The perineum has closely related anatomical structures including the external genital organs and the anal triangle which contains the anal…
- Conditions
- Obstetric Trauma, Perineum; Injury, Perineal Infection, Anal Sphincter Injury
- Trial name
- NCT04480684
- Testing
- Three-dimensional Endoanal Ultrasound, Transperineal Ultrasound(multiplanar), The MolecuLight i:X: Bacterial autofluorescence camera
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Croydon Health Services NHS Trust
Delivery; Trauma, Pelvic Floor; Perineal Rupture, Obstetric
Perineal Preparation for Pregnant Ladies.
Pregnant participants will be recruited at the obstetrics outpatient clinic during their visits 4 weeks before the due date. They are randomized into two groups. The first group will be educated to do digital perineal massage.
- Conditions
- Delivery; Trauma, Pelvic Floor; Perineal Rupture, Obstetric, Pelvic Floor Muscle Weakness
- Trial name
- NCT03287258
- Testing
- 3 program, one program
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Perineal Injury
The Use of St. John's Wort Oil With Massage in the Perineum During Childbirth
Perineal trauma, whether spontaneous or episiotomy, is a condition that affects the quality of life in primiparous women . In women who have experienced perineal trauma, problems such as dyspareunia, urinary and fecal…
- Trial name
- NCT05164926
- Testing
- perineal massage with St. John's Wort oil
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Hemorrhage of Cesarean Section and/or Perineal Wound, Postpartum Hemorrhage
Role Of Different Prophylactic Doses Of Intravenous Tranexamic Acid In Reducing Blood Loss At Caesarean Section
This study aims to define a safe prophylactic intravenous TXA dose with an advantage over others in reducing total blood loss volume at secondary uncomplicated LSCS.
- Trial name
- NCT02739815
- Testing
- Normal Saline containing a prophylactic Antibiotic 1 g, Tranexamic Acid
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Talkha Central Hospital
Perineal Trauma, Pelvic Floor Dysfunction
Pelvic Floor Training Program and Perineal Trauma During Vaginal Birth
This study aims to determine whether a structured pelvic floor muscle training program during pregnancy can reduce perineal trauma during vaginal birth.
- Conditions
- Perineal Trauma, Pelvic Floor Dysfunction, Labor Complications, Pelvic Floor Muscle Training
- Trial name
- PFTP (NCT07292948)
- Testing
- Pelvic Floor Muscle Training Program
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Mehmet Incebıyik
Perineal Tear
Lidocaine, Povidone Iodine, and Honey Application on Second-degree Perineal Tear Healing
This clinical trial aims to compare the effectiveness of the continuous application of lidocaine cream, honey, and povidone-iodine cream in second-degree perineal tear healing.
- Trial name
- NCT05946005
- Testing
- honey, lidocaine, povidone-iodine
- Where
- Indonesia
- Volunteers
- 200 people
- Sponsor
- Hasanuddin University
Perineal Tear, Delivery; Trauma
The Patient Positioning for Perineal Protection Study
It is common practice for practitioners to instruct patients to forcibly flex the hips at the time of delivery of the fetal vertex.
- Conditions
- Perineal Tear, Delivery; Trauma, Perineal Laceration
- Trial name
- 4P (NCT04616170)
- Testing
- Hip extension, Usual Care
- Where
- United States
- Volunteers
- 1,206 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Cesarean Section; Infection, Perineal Infection
Effect of Copper on the Healing of Obstetric Wounds
The most common complication of vaginal delivery is perineal tearing with a prevalence of 85% and 70% will need suturing. The caesarean section rate worldwide is rising and the rate in Croydon University Hospital is in the region…
- Conditions
- Cesarean Section; Infection, Perineal Infection, Wound Infection, Surgical Site Infection
- Trial name
- ECHO (NCT03284749)
- Testing
- Copper impregnated wound dressing, Normal wound dressing, Copper impregnated maternity pads
- Where
- United Kingdom
- Volunteers
- 774 people
- Sponsor
- Croydon Health Services NHS Trust
Perineal Injury, Perineal Laceration, Tear, or Rupture During Delivery
Targeted Deep Pelvic Floor Muscle Physiotherapy Versus Antenatal Perineal Massage in Nulliparous Women
This prospective randomized clinical trial evaluates whether targeted deep pelvic floor muscle physiotherapy is more effective than standard antenatal perineal massage in reducing perineal trauma among nulliparous women.
- Trial name
- NCT07764068
- Testing
- Targeted Deep Pelvic Floor Muscle Physiotherapy, Standard Antenatal Perineal Massage
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Trauma
Levator Ani Muscle Avulsion at First Birth of Mexican Women: Randomized Control Trial
Levator Ani Muscle (LAM) avulsion occurs in 13-36% of women having their first birth. These damages by palpation and ultrasound of the pelvic floor can be detected.
- Trial name
- NCT02513420
- Testing
- Perineal muscle training
- Where
- Mexico
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Perineal Trauma, Postpartum Pain
RELIEVE Study- Platelet-Rich Plasma to Reduce Postpartum Pain After Perineal Tears or Episiotomy
Perineal tears and episiotomies are common after vaginal birth and may cause persistent pain, impaired wound healing, pain during sexual activity, and concerns about genital appearance.
- Conditions
- Perineal Trauma, Postpartum Pain, Episiotomy, Perineal Laceration
- Trial name
- RELIEVE (NCT07727213)
- Testing
- Autologous Non-Activated Platelet-Rich Plasma, Saline (0.9%, sterile, for infusion)
- Where
- Switzerland
- Volunteers
- 160 people
- Sponsor
- University Hospital, Geneva
Perineum; Injury, Anal Incontinence
Efficacy of Antenatal Perineal Massage in Reducing Postpartum Morbidities
A randomized controlled trial was undertaken at Rajavithi Hospital, Bangkok, Thailand, encompassing 106 primigravidae within the period of December 2023 to June 2024.
- Conditions
- Perineum; Injury, Anal Incontinence, Urinary Incontinence
- Trial name
- NCT06162312
- Testing
- Antenatal perineal massage
- Where
- Thailand
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Delivery Problem, Childrearing
Perineal Massage Performed During the Labour
In this study, perineal massage was applied to primiparous women who did not give birth before, as a quasi-experimental control group to determine the effects of massage on birth comfort, perineal trauma and perineal pain.
- Conditions
- Delivery Problem, Childrearing, Satisfaction, Patient, Perineum; Injury
- Trial name
- NCT05962918
- Testing
- Perinal massage
- Where
- Turkey (Türkiye)
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Munzur University
Episiotomy, Lacerations Perineal
Physiotherapeutic Protocol Compared to Usual Care in the Treatment of Primiparas After Perineal Trauma
The aim of this study is to assess the effectiveness of a pelvic floor muscle training (PFMT) protocol associated with cryotherapy initiated in the immediate postpartum period in relieving pain in primiparous women who suffered…
- Conditions
- Episiotomy, Lacerations Perineal, Obstetric Anal Sphincter Injury, Perineal Injury
- Trial name
- MPR (NCT07170007)
- Testing
- Physiotherapeutic protocol, Usual maternity care
- Where
- Brazil
- Volunteers
- 82 people
- Sponsor
- University of Sao Paulo
Pelvic Pain
Impact of Thermotherapy During Childbirth on Postpartum Perineal Pain (PERISAFE)
Perineal pain is common after vaginal birth. Thermotherapy might be effective to limit postpartum perineal pain, thanks to the effects of local heating or cooling application.
- Trial name
- PERISAFE (NCT04778631)
- Testing
- Heat therapy, Cryotherapy
- Where
- 2 sites in France
- Volunteers
- 115 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pregnancy Complications
Obstetric Perineal Trauma and Physiotherapy
The main objective is to investigate effects of perineal trauma at birth on women´s health and whether early physiotherapy improves pelvic floor strength.
- Trial name
- NCT02682212
- Testing
- Physiotherapy intervention
- Where
- Iceland
- Volunteers
- 84 people
- Sponsor
- Landspitali University Hospital
Perineum; Injury
Impact of the Puncture of the RP6 Point on the Ampliation and Injuries of the Perineum During Childbirth
During the study period, any patient who enters labour and reports to the maternity ward and meets the inclusion and non-inclusion criteria is offered to participate in the study by the midwife acupuncturist present.
- Trial name
- PELVIPUNCTURE (NCT04128033)
- Testing
- Puncture of the RP6 point
- Where
- France
- Volunteers
- 350 people
- Sponsor
- Centre Hospitalier Sud Francilien
Perineal Trauma, Obstetric Anal Sphincter Injury
Papaverine for Prevention of Perineal Trauma
Perineal trauma is a common complication of vaginal delivery, particularly among primiparous patients, and may result in short- and long-term maternal morbidity, including pain, dyspareunia, and pelvic floor dysfunction.
- Trial name
- NCT07641543
- Testing
- Papaverine Hydrochloride
- Volunteers
- 412 people
- Sponsor
- Dr Raneen Abu Shqara
Episiotomy, Platelet Rich Plasma (PRP)
Platelet-Rich Plasma Versus Standard Care for Episiotomy Wound Healing in Postpartum Women
This study looks at whether a treatment made from a patient's own blood, called platelet-rich plasma (PRP), can help heal the cut made during childbirth (episiotomy) better than standard care alone.
- Conditions
- Episiotomy, Platelet Rich Plasma (PRP), Wound Healing, Obstetric
- Trial name
- PRP-EpiHeal (NCT07669285)
- Testing
- Autologous Platelet-Rich Plasma (PRP), Standard Wound Care
- Where
- Romania
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Saint Andrew Hospital Constanta