Clinical trials: Periodontal Disease
Gingival Cleft, Orthodontic Space Closure
Gingival Cleft Development at Two Time Points of Canine Retraction
The goal of this split-mouth randomized controlled trial is to assess whether the timing of extraction space closure-early vs. delayed initiation-affects the incidence of gingival cleft development in orthodontic patients.
- Trial name
- NCT07210762
- Testing
- Early space closure, Delayed space closure
- Where
- Pakistan
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Bahria University
Gingival Recession, Mucogingival Surgery
V-Reverse Suture Technique Compared to Traditional Anchored Sling Suture in Treating Multiple Gingival Recession
The goal of this split-mouth pilot study is to study the effect of two different suturing techniques in root coverage using coronally advanced flap tunnel in multiple adjacent recession cases to see which technique will give…
- Trial name
- NCT07602829
- Testing
- coronally advanced tunnel with v-reverse suture, coronally advanced tunnel with anchored sling suture
- Where
- Jordan
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Peri-Implantitis and Peri-implant Mucositis, Peri-Implantitis and Systemic Inflammation
Longitudinal Evaluation of Regenerative Treatment of Peri-implantitis Assited by Er,Cr:YSGG Laser: up to 10 Years Follow-up
Peri-implantitis is a pathological condition characterized by the inflammation of peri-implant connective tissues and progressive alveolar bone loss.
- Trial name
- Laser (NCT07104760)
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Guarulhos
Periodontitis, Diagnoses Disease
The Impact of a Modified Probe Tip Design on Patient Perception of Discomfort on Probing and Clinical Parameters Using the Florida Probe® System
Patient perception of pain on periodontal probing using a controlled-force, electronic probe was not significantly affected by the use of a modified (ball-end) probe tip design except for in the maxilla, where a standard straight…
- Trial name
- NCT03690479
- Testing
- Florida Probe Straight Tip Probe, Ball Tip Probe
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Florida
Periodontitis
Comparing the Outcomes of Incisions Made by Colorado® Microdissection Needle
The aim of the present study was to compare the outcomes of incisions made by Colorado® microdissection needle, electrosurgery tip and surgical blade during periodontal surgery.
- Trial name
- NCT03003624
- Testing
- Colorado® microdissection needle, Cautery tip, BP blade
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- SVS Institute of Dental Sciences
Chronic Periodontitis
Effect Of A Locally Delivered Probiotic Sacchraomyces Boulardii In The Management Of Chronic Periodontitis
This study was carried out in the Department of Periodontology and source of patient was be from the outpatient section of Tatyasaheb Kore Dental College \& Research Centre, New Pargaon.
- Trial name
- NCT03516370
- Testing
- Saccharomyces Boulardii 250 MG
- Where
- India
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Tatyasaheb Kore Dental College
Periodontal Diseases, Inflammation
Effect of Systemic Retinoic Acid Use on Micro Ribonucleic Acid (mRNA) Expression
Ribonucleic acids (RNA) are molecules that transfer genetic information from the nucleus to the cytoplasm for protein translation.
- Trial name
- NCT07142070
- Testing
- Saliva, serum sampling, oral isotretinoin
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Medipol University
Alveolar Bone Loss
Effectiveness in Limiting the Need to Elevate the Maxillary Sinus
The aim of the present study is to evaluate the effectiveness of different alveolar preservation procedures performed at the time of extraction of the first or second upper molar in avoiding a maxillary sinus elevation or at…
- Trial name
- SO-GHI (NCT03357705)
- Testing
- alveolar ridge preservation with synthetic bone, alveolar ridge preservation with bovine collagen
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Gingival Recession
Connective Tissue Grafting for Single Tooth Recession & the Impact of the Thickness of the Palatal Harvest Tissue
The purpose of this study is to test if the thickness of the graft taken from the roof of the mouth, has a significant effect on the amount of attached tissue and the amount of root coverage that are attained when treating a…
- Trial name
- NCT03032094
- Testing
- connective tissue graft
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Columbia University
Periodontitis, Gingivitis
Evaluation of Salivary Biomarker Levels in Individuals With Different Periodontal Conditions
In order to determine the pathogenesis of chronic inflammatory diseases, the levels of various cytokines are examined in tissues and fluids taken from the body.
- Conditions
- Periodontitis, Gingivitis, Periodontal Health
- Trial name
- NCT06558136
- Testing
- Saliva obtaining
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Peri-implant Mucositis, Peri-Implantitis
Chitosan Brushes vs Air-Abrasive Devices on Peri-implant Mucositis Treatment: A Randomized Clinical
Bleeding on probing (0,1,2,3), plaque index (+,-) and pocket probing depth will be recorded for each visit. Before the procedure, the patient will be randomly assigned to one of four groups and records will be kept.
- Conditions
- Peri-implant Mucositis, Peri-Implantitis, Bleeding on Probing, Periodontal Pocket
- Trial name
- NCT06287957
- Testing
- Labrida BioClean, EMS Handy 3.0 Perio Premium
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Periodontitis
A Closed Surgical Technique vs Papilla Preservation Techniques
A pioneer periodontal surgical approach employing the closed surgical technique (CST) has been designed to gain access to isolated interdental periodontal defects and retain the soft-tissue architecture.
- Trial name
- CST (NCT05754307)
- Testing
- Access Flap, Closed Surgical Technique
- Where
- Greece
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Danae A. Apatzidou
Periodontitis, Chronic, Chewing Problem
Assessment of Masticatory Performance in Periodontitis
The loss of periodontal attachment contributes to reduced masticatory performance and has a negative impact on general health.This clinical trial aims to assess the status of masticatory performance among patients with stage I…
- Conditions
- Periodontitis, Chronic, Chewing Problem, Inflammation
- Trial name
- NCT06426069
- Testing
- Masticatory efficiency assessment
- Where
- India
- Volunteers
- 555 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Gingival Recession
Comparison of Root Coverage Outcomes by NORD Flap Versus Subepithelial Connective Tissue Graft in RT1 Gingival Recession
Management of GR in the initial stages (when there is no inter proximal attachment and bone loss involved) has better clinical outcomes and reduces the chances of further progression of recession.
- Trial name
- Recession type (NCT05844254)
- Testing
- novel overlapping rotated double (NORD) flap
- Where
- India
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Peri-Implantitis
Ozone Therapy as an Adjunct to the Surgical Treatment of Peri-implantitis
Decontamination procedure is a challenging factor that affects the success of surgical regenerative therapy (SRT) of peri-implantitis.
- Trial name
- NCT03018795
- Testing
- Decontamination of implant surfaces
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Gazi University
Peri-implant Mucositis, Gingivitis
Experimental Peri-implant Mucositis in Humans
This is a pilot study. The investigators hypothesize that the peri-implant soft tissue response to de novo plaque accumulation is similar to that of normal gingival tissue in the same subjects.
- Trial name
- NCT01941797
- Testing
- interruption of oral hygiene
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- UConn Health
Gingival Recession
Use of Platelet Rich Fibrin in Addition to CAF and SCTG for Treatment of Gingival Recession
This research will be conducted in an attempt to achieve complete root coverage with physiologic probing depth and a harmonious view with the adjacent tissues using Platelet rich fibrin in conjunction with Coronally advanced flap…
- Trial name
- NCT03199118
- Testing
- CAF +SCTG, platelet rich fibrin
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession, Localized
Comparing Two Different Tunneling Technique for Gingival Recession Treatment Using Two Different Matertial
The goal of this clinical trial is to compare two different tunneling surgical technique in treatment of gingival recession using two different materials.
- Trial name
- NCT06065774
- Testing
- The Laterally Closed Tunnel Technique with SCTG, The Laterally Closed Tunnel Technique with collagen matrix mucograft, Modified Coronally Advanced Tunnel Technique with SCTG.
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Gingival Recession, Gingival Recession, Localized
The Effect of Using Injectable Platelet-rich Fibrin on Root Surface Closure in Patients with Gingival Recession.
Gingival recession is the term used to describe the apical positioning of the marginal gingiva from the enamel-cementum junction.
- Trial name
- NCT05591326
- Testing
- i-PRF application procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Berceste Guler
Alveolar Bone Loss
Biologically Oriented Alveolar Ridge Preservation (BARP) With and Without Advanced Platelet-Rich Fibrin Plus (A-PRF+)
Twenty patients were selected from the outpatient clinic of the Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Mansoura University seeking for extraction of non-restorable maxillary premolar teeth prior to…
- Trial name
- NCT07869082
- Testing
- Socket preservation by deproteinized bovine bone graft, socket preservation by deproteinized bovine bone graft mixed with advanced PRF+
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
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