Clinical trials: Periodontal Diseases
Chronic Kidney Diseases, Caries,Dental
Assessment of The Oral Health Status of Children With Chronic Kidney Disease
The aim of this study is to compare the oral health findings, salivary parameters and disease-related quality of life of children with different stages of Chronic Kidney Disease(CKD), those undergoing dialysis and…
- Conditions
- Chronic Kidney Diseases, Caries,Dental, Quality of Life, Saliva Altered
- Trial name
- NCT06578832
- Testing
- physical and chemical methods, biochemical methods, biochemical tests
- Where
- Turkey (Türkiye)
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Marmara University
Periodontal Diseases
The Accuracy of Infrared Thermographic Imaging for Assessment of Periodontal Status
The diagnosis and differentiation between periodontal diseases are currently based on the measuring and interpretation of full-mouth clinical and radiographic criteria.
- Trial name
- NCT06290414
- Testing
- infrared thermal camera
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Gingival Recession
Gingival Recession (RT1) Treatment With Different Gingival Augmentation Surgeries
Thin gingival phenotype is one of the major causative factors of gingival recession type 1 which can result in hypersensitivity, discomfort, and compromised esthetics.
- Trial name
- NCT05688293
- Testing
- Connective tissue graft, Free gingival graft, Non surgical
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Misr International University
Tooth Loss
Ridge Expansion in the Maxillary Aesthetic Zone Using Piezo-electric Surgery
In this split-mouth controlled study, implants placed using the alveolar ridge expansion technique will be compared to those placed in native bone with sufficient horizontal bone width.
- Trial name
- NCT01796119
- Testing
- Ridge Splitting, Implants placed using drilling technique
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Clinique Dentaire et d'implantologie Dr.Vinh Nguyen
Dental Pulp Disease, Periapical Diseases
Effect of MTAD on The Outcome of Primary Root Canal Treatment
The aim of this clinical study was to compare the radiographic outcome of a root canal treatment with or without use of MTAD after 24 months recall.
- Conditions
- Dental Pulp Disease, Periapical Diseases, Tooth, Nonvital
- Trial name
- NCT05555563
- Testing
- MTAD irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Peri-Implantitis
Patient Perception and Clinical Efficacy of a Collagen Matrix for the Treatment of Peri-implantitis
This is a multi-centre, randomized clinical trial which evaluates the efficiency of the collagen xenograft (Muco-Graft®) in comparison to the autologous connective tissue graft for the augmentation of keratinized mucosa and…
- Trial name
- NCT03551145
- Testing
- Acellular collagen matrix, Autogenous free gingival graft
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Gingivitis
Comparison of the Effects of Oil Pulling Therapy With Different Oils
Oil pulling" or "oil swishing" originates from ancient Ayurvedic medicine in India and now practiced in other parts of the world as a form of complementary and alternative medicine.
- Trial name
- NCT04737798
- Testing
- oil pulling with coconut oil, oil pulling with sesame oil
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Baskent University
Periodontitis
Effects of Azithromycin as an Adjunct to Scaling and Root Planning in the Treatment of Periodontitis
The growing interest in the possibilities of modulating macrophages in inflammatory diseases with therapeutic purpose has prompted the development of new approaches for the treatment of periodontitis.
- Trial name
- NCT05506371
- Testing
- Az+SRP, SRP, No interventions
- Where
- Ukraine
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ukrainian Medical Stomatological Academy
Recession, Gingival
Toothbrush in the Genesis and Prevention of Dental Recessions
The aim of this research is to evaluate the effect of brushing on gingival recessions and to understand the impact of manual brushing and brushing with mechanical aid on their evolution.
- Trial name
- Recession (NCT05949112)
- Testing
- soft bristle toothbrush, mechanical toothbrush
- Where
- Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universita degli Studi di Genova
Periodontal Diseases
The Effect of an Antioxidant Gel Compared to Chlorhexidine Gel During the Soft Tissue Healing Process: A Randomized Controlled Clinical Trial
This study aims to evaluate the comparative impact of chlorhexidine and antioxidant gel on postoperative biomarkers following SRP.
- Trial name
- Antiox-SRP (NCT06894667)
- Testing
- Antioxidant gel, Antimicrobial gel
- Where
- Kuwait
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kuwait University
Periodontal Pocket
The Proposed Study Aims to Investigate the Efficacy of Quercetin as an Adjunctive to Mechanical Debridement in Treatment of Periodontitis
the proposed study aims to investigate the effect of Quercetin in treatment of periodontitis patients
- Trial name
- NCT06982248
- Testing
- NSP and chitosan nanoparticles gel loaded by quercetin, NSP and chitosan nanoparticles gel, scaling and root planning
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Periodontitis
Use of Hyaluronic Acid Gel in Intraosseous Defects
Aim: The aim of this randomised, parallel-arm, blinded, controlled clinical trial was to compare the clinical and radiographic efficacy of MINST with and without 0.8% HA gel application in the treatment of intraosseous defects.
- Trial name
- NCT06214728
- Testing
- Hyaluronic acid gel application
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Post-osseointegration Biological Failure of Dental Implant, Alveolar Bone Loss
The Influence of Mucosal Tissue Thickness on Soft and Hard Tissue Changes Around Implants
Crestal bone and soft tissue stability around implants is an important issue in implant dentistry. Initial vertical mucosal tissue thickness was shown to be one of the factors having impact on bone stability.
- Trial name
- NCT02580721
- Testing
- Dentsply Astra Tech Implant System EV
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Rheumatoid Arthritis, Periodontal Disease
Periodontal Inflammation and Immunity in Preclinical Rheumatoid Arthritis
The purpose of this study is to evaluate the association of Rheumatoid Arthritis (RA)-related antibodies and periodontal inflammation in subjects at-risk for Rheumatoid Arthritis.
- Trial name
- NCT02794012
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Peri-Implantitis
SPiT-frequency; the Effect of Increased Frequency of Intervention on Post-surgical Peri-implant Inflammation
This pilot study is an interventional clinical study on the supportive peri-implant treatment (SPiT) necessary to maintain/ improve the clinical conditions surrounding a dental implant following surgical treatment of…
- Trial name
- SPiT-freqvzy (NCT04705012)
- Testing
- Submucosal supportive therapy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Maxilla, Tooth Loss / Rehabilitation
Loading Protocols for Dental Implants Placed in Healed Fully Edentulous Maxilla
The goal of this clinical trial is to compare immediate versus early loading protocols for complete implant-supported fixed dental prostheses in healed edentulous maxillae.
- Trial name
- NCT07574099
- Testing
- Immediate implant loading, Early loading
- Where
- Serbia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Post-operative Pain, Apical Periodontitis
The Effect of Different Irrigation and Disinfection Methods on Post-operative Pain (PP)
Aim: The aim of this study was to examine post-operative pain (PP) severity after conventional irrigation and sonic activation methods, with and without laser disinfection in mandibular molar teeth diagnosed with symptomatic…
- Trial name
- PP (NCT05195021)
- Testing
- EDDY, Diode Laser device, Conventional irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Biruni University
Periodontitis (Stage 3), Periodontal Health
Evaluation of the Effect of Smoking on Apelin, Periostin, and High-Sensitivity CRP Levels in Gingival Crevicular Fluid and Serum
Periodontal health is influenced by various local and systemic factors, with smoking being one of the major environmental risk factors.
- Conditions
- Periodontitis (Stage 3), Periodontal Health, Smoking Cigarette
- Trial name
- NCT07870473
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Periodontitis, Adult
Non-surgical Periodontal Treatment in Smokers on SIRT-1, NLRP3 Inflammasome and LncRNAs
The goal of this observational is to analyze the relationship between levels of interleukin-18 (IL-18), interleukin (IL-1β), Tumor Necrosis Factor-alpha (TNF-α), interleukin-10 (IL-10), transforming growth factor beta (TGF-β)…
- Trial name
- NCT06351722
- Testing
- Before non-surgical periodontal treatment, non-surgical periodontal treatment, 3rd month after non-surgical periodontal treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Gingival Inflammation, Gingival Bleeding
Evaluation of a Toothpaste Containing a Gum Health Active in Participants With Gingival Problem
The primary objective of this clinical study is to evaluate the impact on gingival health when participants switch to a fluoride toothpaste without gum-health actives for 4 weeks after using a proven gum-health toothpaste for 13…
- Conditions
- Gingival Inflammation, Gingival Bleeding, Dental Plaque
- Trial name
- NCT07415733
- Testing
- Test Toothpaste, Control Toothpaste
- Where
- Indonesia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
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