Clinical trials: Perioperative Bleeding
Abdominal Aortic Aneurism, Abdominal Aortic Rupture
Haemostasis Management of Abdominal Aortic Procedures
Comparative study on efficacy of haemostatic therapy guided either by standard laboratory coagulation parameters or point-of-care testing in patients undergoing vascular surgical procedures.
- Conditions
- Abdominal Aortic Aneurism, Abdominal Aortic Rupture, Perioperative/Postoperative Complications, Surgical Blood Loss
- Trial name
- NCT03426839
- Testing
- Coagulation tests
- Volunteers
- 40 people
- Sponsor
- University of Pecs
Osteoarthritis, Knee
Tranexamic Acid and Drain Use in Knee Arthroplasty
This prospective randomized clinical study is designed to evaluate the effects of intra-articular tranexamic acid (TNA), with or without suction drainage, on perioperative blood management in patients undergoing total knee…
- Trial name
- TNAKnee (NCT07174895)
- Testing
- Intra-articular Tranexamic Acid + Suction Drainage, Intra-articular Tranexamic Acid, Suction Drainage Only
- Where
- Syria
- Volunteers
- 192 people
- Sponsor
- Idlib University
Blood Loss, Surgical
Non-invasive Perioperative Hb Monitoring in Spinal Surgery
The decision to transfuse or not to transfuse blood products is one of the main issues in patients undergoing surgery. The standard laboratory method of hemoglobin assessment is time-consuming, gives intermittent data, and…
- Trial name
- NCT02908412
- Testing
- Digital nerve block with bupivacaine
- Where
- Iran
- Volunteers
- 23 people
- Sponsor
- Tehran University of Medical Sciences
Spinal Injuries, Spinal Deformity
Tranexamic Acid to Reduce Blood Loss in Spine Surgery
This study is designed to evaluate the efficacy of topical tranexamic acid to reduce perioperative blood loss, reduction in postoperative drain output and allogenic transfusion requirements.
- Trial name
- NCT02314988
- Testing
- Tranexamic Acid
- Where
- 4 sites in United States
- Volunteers
- 252 people
- Sponsor
- Columbia University
Clopidogrel
Does Continued Use of Clopidogrel Into Surgery Cause Increased Perioperative Bleeding?
Patients who on taking clopidogrel are randomized to either continue clopidogrel into general surgery or discontinue clopidogrel 7 days before surgery. All patients resume clopidogrel after surgery.
- Trial name
- NCT01960296
- Testing
- Clopidogrel, Discontinue Clopidogrel
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Cancer, Tumour
The HeLiX (Hemorrhage During Liver Resection: traneXamic Acid) Trial
This is a Phase III multicentre randomized controlled trial (RCT) to evaluate the impact of tranexamic acid (TXA) on perioperative blood transfusion in patients undergoing liver resection.
- Conditions
- Cancer, Tumour, Surgery
- Trial name
- HeLiX (NCT02261415)
- Testing
- Tranexamic acid (TXA), Normal saline
- Where
- 11 sites in United States, Canada
- Volunteers
- 1,386 people
- Sponsor
- Sunnybrook Health Sciences Centre
Coxarthrosis, Arthroplasties Hip Replacement
Use of Etoricoxib Compared to Diclofenac in the Perioperative Treatment of Patients After Total Hip Arthroplasty
The primary aim of this study is to test if etoricoxib decreases the perioperative blood loss compared to diclofenac. Secondary questions to be explored are: Does etoricoxib prevent Heterotopic ossification after Total Hip…
- Conditions
- Coxarthrosis, Arthroplasties Hip Replacement, Perioperative Blood Loss
- Trial name
- NCT01229774
- Testing
- Etoricoxib, Diclofenac
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Regensburg
Scoliosis; Adolescence, Bleeding
The Effects of Fibrinogen Concentrate Infusion on Blood Loss and Allogeneic Blood Conservation in Scoliosis Surgery
Allogeneic blood products transfusions are often necessary to treat perioperative bleeding in patients undergoing complex scoliosis surgeries.
- Conditions
- Scoliosis; Adolescence, Bleeding, Surgery
- Trial name
- NCT03183479
- Testing
- Fibrinogen Concentrate Human, Normal saline
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Peking Union Medical College Hospital