Clinical trials: Perioperative Care
Laparoscopic Cholecystectomy
ERAS (Enhanced Recovery After Surgery) and Multimodal Analgesia in Laparoscopic Cholecystectomy
This clinical study aims to evaluate the effects of multimodal analgesia management administered within an ERAS (Enhanced Recovery After Surgery) protocol on postoperative pain, length of hospital stay, early complications, and…
- Trial name
- ERAS (NCT06885086)
- Testing
- Control group - 1, Observation group -2
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Perioperative Care, EEG Power Spectra
Extended Emergence Strategy on Post-Anesthesia Care Unit Events After Outpatient Orthopedic Surgery
The goal of this clinical trial is to learn if an extended emergence from anesthesia can improve recovery room (Post-Anesthesia Care Unit or PACU) outcomes in lower-leg or foot surgery with nerve blocks.
- Conditions
- Perioperative Care, EEG Power Spectra, Delirium - Postoperative
- Trial name
- PACU-EMERGE (NCT07533370)
- Testing
- Standard of Care EEG-Guided Emergence, Extended EEG Emergence Trajectory
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Harrison Shong-Wen Chow
Perioperative Care
Perioperative Care in Ethiopia
A national cross-sectional survey of surgery and anaesthesia at Ethiopian public hospital facilities.
- Trial name
- NCT04724122
- Testing
- Observational / Assessment only
- Where
- Ethiopia
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Network for Perioperative Critical Care
Knee Prosthesis
Effect of Normothermia Care Bundle in Knee Replacement Surgery
Osteoarthritis is a disease characterized by disruption of the integrity of articular cartilage as a result of erosion of articular cartilage.
- Trial name
- NCT06454877
- Testing
- active heating, pasive heating
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Clinical Safety of a PBM Program
The German Patient Blood Management Network
This epidemiological trial will determine whether the implementation of a PBM program is safe and effective in terms of clinical outcome compared to a pre-implementation cohort Primary endpoint is a composite outcome comprising…
- Trial name
- NCT02147795
- Where
- 2 sites in Germany
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital
Pressure Ulcer (PU), Pressure Injury Prevention
Effect of a Risk-Based Perioperative Pressure Injury Prevention Bundle in Elective Surgery Patients
This study evaluates whether a risk-based perioperative pressure injury prevention bundle reduces the development of pressure injuries in patients undergoing elective surgery lasting 3 hours or longer.
- Conditions
- Pressure Ulcer (PU), Pressure Injury Prevention, Perioperative Care, Braden Scale
- Trial name
- RiPPB (NCT07725068)
- Testing
- Risk-Based Perioperative Pressure Injury Prevention Bundle
- Where
- Turkey (Türkiye)
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Music Therapy, Anxiety
Therapy on Perioperative Anxiety and Pain in Patients
This study aims to explore the effects of preoperative education combined with intraoperative music therapy on perioperative anxiety and pain in patients undergoing elective cesarean section.
- Conditions
- Music Therapy, Anxiety, Health Education
- Trial name
- NCT06970431
- Testing
- eoperative Education + Intraoperative Music Therapy Arm, Preoperative Education Alone Arm
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Maternal and Child Health Hospital of Hubei Province
Pelvic Organ Prolapse
Effects of a Follow-up Based Nursing Care Protocol on Pelvic Organ Prolapse
The goal of this clinical trial is to evaluate the effects of a follow-up-based nursing care protocol-implemented during the perioperative and post-discharge home care processes-on pelvic organ prolapse symptoms, quality of life…
- Trial name
- NCT06631508
- Testing
- Follow-up-based Nursing Care Protocol, Control Group: Routin Care
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Staphylococcus Aureus, Health Care Associated Infection
Reducing Perioperative S. Aureus Transmission
The purpose of this study is to prevent the spread of S. aureus, a dangerous bacterium, within the operating room and between patients undergoing surgery.
- Conditions
- Staphylococcus Aureus, Health Care Associated Infection, Health Care Worker Patient Transmission
- Trial name
- NCT03638947
- Testing
- Swab and decolonization using povidone-iodine cleansing
- Where
- United States
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Randy Loftus
Opioid-use Disorder, Pain, Acute
Effect of Buprenorphine/Naloxone Continuation on Pain Control and Opioid Use
The aim of this study is to determine the effect of continuation of buprenorphine/naloxone in patients with history of Opioid Use Disorder (OUD) scheduled for surgery compared to reduced dose buprenorphine/naloxone prior to…
- Conditions
- Opioid-use Disorder, Pain, Acute, Surgery
- Trial name
- NCT03266445
- Testing
- buprenorphine/naloxone
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Preoperative, Anesthesia
Role of Anesthesiologist-Patient Relationship
Descriptive analytic survey of 1137 and 518 patients aged 16 years or more before and after anesthesia exposure, respectively to assess the anesthesiologist-patient relationship role on patient postoperative perception of the…
- Conditions
- Preoperative, Anesthesia, Postoperative
- Trial name
- NCT00864695
- Testing
- Supportive care
- Where
- Brazil
- Volunteers
- 1,137 people, healthy volunteers welcome
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Colorectal Cancer, Surgery
Human Blood Specimen Collection to Evaluate Immune Cell Function
Natural killer (NK) cells are leukocytes of the innate immune system and play a central role in the control of cancer metastases.
- Conditions
- Colorectal Cancer, Surgery, Perioperative Care
- Trial name
- NCT03422120
- Testing
- Natural Killer Cell Activity Assay
- Where
- Canada
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Preoperative Anxiety
A Mobile Application for Child-focused Perioperative Education
The investigators developed a child-friendly mobile application to support accessible, interactive patient/caregiver education about pediatric tonsillectomy.
- Trial name
- NCT06054282
- Testing
- "Ready for Tonsillectomy" educational mobile application
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Children's Healthcare of Atlanta
Anesthesia, Hip Fractures
Anesthesia and Perioperative Neurocognitive Disorders in the Elderly Patients Undergoing Hip Fracture Surgery Platform Trial (ANDES Platform Trial)
The ANDES Platform Trial is a pragmatic, multicenter, adaptive randomized controlled platform trial in patients aged 65 years or older undergoing surgery for hip fracture.
- Conditions
- Anesthesia, Hip Fractures, Dementia, Cognitive Impairment
- Trial name
- ANDES platform (NCT06452147)
- Testing
- Nerve block, Standard anesthesia care, Bupivacaine liposome
- Where
- 13 sites in China
- Volunteers
- 1,860 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Perioperative Pain, Perioperative Anxiety
The Use of Virtual Reality to Reduce Anxiety and Pain in Perioperative Settings
We will investigate whether the use of Virtual Reality (VR) preoperatively and intraoperatively can help treat pain and anxiety, as measured by patient feedback, vital signs trends, and the amounts of anesthetics, pain…
- Trial name
- NCT03744845
- Testing
- Virtual Reality Distraction
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Intratracheal Intubation, Laryngoscopes
Incidence of Sore Throat With Traditional Intubation Blades or Glidescope Blade
The purpose in this study is to determine whether there is a difference in the incidence of postoperative sore throat when using the GlideScope™ versus a traditional intubation blade involving patients that are not anticipated to…
- Conditions
- Intratracheal Intubation, Laryngoscopes, Postoperative Care, Risk Assessment
- Trial name
- NCT02033564
- Testing
- Macintosh/Miller Laryngoscope, Glidescope Laryngoscope
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Jason Ngo, B.S.
Myocardial Infarction Postoperative, Myocardial Injury
Preoperative BNP: Epidemiological Patterns, Management Strategies and Cost Analysis of Care
Recently, the use of preoperative BNP as a preoperative risk stratifcation tool was added to the Canadian Cardiovascular Society (CCS) guidelines (4) on perioperative cardiac risk assessment and management for patients who…
- Conditions
- Myocardial Infarction Postoperative, Myocardial Injury, Death, Cardiac
- Trial name
- NCT04077294
- Testing
- Cardiac risk stratification using preoperative BNP measurement, followed by postoperative cardiac monitoring, Use of traditional perioperative cardiac risk stratification only
- Where
- Canada
- Volunteers
- 333 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Postoperative Thirst, Comfort
Effect of Postoperative Oral Rinsing on Dehydration-Related Discomfort, Comfort, and Bowel Sounds
The aim of this study is to evaluate the effects of oral rinsing with water in the postoperative period on thirst, comfort level, and bowel motility in patients undergoing abdominal surgery under general anesthesia.
- Conditions
- Postoperative Thirst, Comfort, Bowel Movements, Abdominal Surgeries
- Trial name
- NCT07236749
- Testing
- oral rinsing, rutine service operation
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Postoperative Atelectasis
Supine vs Prone Position and Atelectasis Assessed by Lung Ultrasound
Atelectasis frequently develops during and after general anesthesia due to factors such as anesthesia-induced diaphragmatic dysfunction, reduced functional residual capacity, altered ventilation-perfusion matching, and surgical…
- Trial name
- LUS-ATELEC (NCT07320092)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Surgery
The ImPreSS Trial: Pharmacogenomic Decision Making at Time of Surgery
The study is enrolling adults who are scheduled for either inpatient or outpatient elective surgical procedures at The University of Chicago.
- Trial name
- NCT03729180
- Testing
- Routine Elective Surgery- In patient or out patient elective surgery, Blood test for genetic testing, Drug-genetic Profile
- Where
- United States
- Volunteers
- 1,900 people, healthy volunteers welcome
- Sponsor
- University of Chicago