Clinical trials: Perioperative Care
Perioperative Care
Perioperative Fluid Therapy from the Perspective of an Anesthesiologist
A survey conducted in 2022 in ,,Medycyna Praktyczna'' magazine, publishing house regarding fluid therapy in hospital wards showed that many recommendations regarding proper fluid therapy have become common practice, but there are…
- Trial name
- PFT (NCT06675253)
- Where
- Poland
- Volunteers
- 913 people, healthy volunteers welcome
- Sponsor
- Medical University of Silesia
Opioid-use Disorder, Pain, Acute
Effect of Buprenorphine/Naloxone Continuation on Pain Control and Opioid Use
The aim of this study is to determine the effect of continuation of buprenorphine/naloxone in patients with history of Opioid Use Disorder (OUD) scheduled for surgery compared to reduced dose buprenorphine/naloxone prior to…
- Conditions
- Opioid-use Disorder, Pain, Acute, Surgery
- Trial name
- NCT03266445
- Testing
- buprenorphine/naloxone
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Major Injury
Perioperative Research Into Memory: Cognitive Outcome Following Major Burns
The long term survival of patients who require admission to critical care (CC) following a major burn injury (MBI) continues to improve with advanced clinical management.
- Trial name
- PRiMe (NCT03470844)
- Testing
- Face-to-face neurocognitive tests, Psychological screening, fMRI
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Hypothermia, Perioperative Care
Effect of Preoperative Active Warming and Passive Warming Methods on Perioperative Hypothermia
70% of surgical interventions are abdominal surgeries. Open abdominal surgery is performed in patients for whom minimally invasive approaches are not suitable.
- Conditions
- Hypothermia, Perioperative Care, Vital Signs, Rewarming
- Trial name
- NCT04997694
- Testing
- Pre Heating
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Osteoarthritis
Tranexamic Acid in Knee Joint Surgery
Total knee joint replacement surgery can lead to significant blood loss, which can affect recovery after surgery. Tranexamic acid (TXA) is a medication which stops the breakdown of blood clots and therefore prevents blood loss.
- Trial name
- TRACKS (NCT02278263)
- Testing
- Tranexamic Acid, Normal saline (0.9% NaCl)
- Where
- 5 sites in New Zealand
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Andrew G Hill, MBChB, MD (Thesis), EdD, FACS, FRACS
Laparoscopic Cholecystectomy
ERAS (Enhanced Recovery After Surgery) and Multimodal Analgesia in Laparoscopic Cholecystectomy
This clinical study aims to evaluate the effects of multimodal analgesia management administered within an ERAS (Enhanced Recovery After Surgery) protocol on postoperative pain, length of hospital stay, early complications, and…
- Trial name
- ERAS (NCT06885086)
- Testing
- Control group - 1, Observation group -2
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Cognitive Dysfunction, Burns
PRIME: Cognitive Outcome Following Major Burns
PRIME aims to demonstrate through neurocognitive assessment that BICU patients will have a degree of neurocognitive dysfunction following a major burn, that this neurocognitive dysfunction is due to an underlying…
- Conditions
- Cognitive Dysfunction, Burns, Inflammation, Brain, Quality of Life
- Trial name
- PRIME (NCT03242395)
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Anesthesia, Hip Fractures
Anesthesia and Perioperative Neurocognitive Disorders in the Elderly Patients Undergoing Hip Fracture Surgery Platform Trial (ANDES Platform Trial)
The ANDES Platform Trial is a pragmatic, multicenter, adaptive randomized controlled platform trial in patients aged 65 years or older undergoing surgery for hip fracture.
- Conditions
- Anesthesia, Hip Fractures, Dementia, Cognitive Impairment
- Trial name
- ANDES platform (NCT06452147)
- Testing
- Nerve block, Standard anesthesia care, Bupivacaine liposome
- Where
- 13 sites in China
- Volunteers
- 1,860 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Cardiovascular Complications, Myocardial Infarction
Ankle-Brachial Index Estimating Cardiac Complications After Surgery
Introduction: Patients undergoing noncardiac surgery are at increased risk of cardiovascular complications. The development of methods that can accurately predict the occurrence of these events is of critical importance and large…
- Conditions
- Cardiovascular Complications, Myocardial Infarction, Acute Coronary Syndromes
- Trial name
- ABRACOS (NCT01452282)
- Where
- Brazil
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Postoperative Thirst, Comfort
Effect of Postoperative Oral Rinsing on Dehydration-Related Discomfort, Comfort, and Bowel Sounds
The aim of this study is to evaluate the effects of oral rinsing with water in the postoperative period on thirst, comfort level, and bowel motility in patients undergoing abdominal surgery under general anesthesia.
- Conditions
- Postoperative Thirst, Comfort, Bowel Movements, Abdominal Surgeries
- Trial name
- NCT07236749
- Testing
- oral rinsing, rutine service operation
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Perioperative Complication, Perioperative/Postoperative Complications
Registry of Anesthesia and Perioperative Medicine
To assess mortality and morbidity associated to anesthesia interventions
- Conditions
- Perioperative Complication, Perioperative/Postoperative Complications, Anesthesia Morbidity, Anesthesia; Adverse Effect
- Trial name
- RAMP (NCT05869578)
- Testing
- Anesthesia Intervention
- Where
- Chile
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Clinica Alemana de Santiago
Enhanced Recovery After Surgery, Perioperative Care
RIDECLAS: Delphi Classification of RICA Pathway Recommendations
RIDECLAS is an observational, prospective, non-interventional consensus study using a modified Delphi methodology. The study aims to obtain expert consensus on the classification and final formulation of recommendations for the…
- Conditions
- Enhanced Recovery After Surgery, Perioperative Care, Surgical Care
- Trial name
- RIDECLAS (NCT07615855)
- Testing
- Modified Delphi questionnaire
- Where
- Spain
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Pelvic Organ Prolapse
Effects of a Follow-up Based Nursing Care Protocol on Pelvic Organ Prolapse
The goal of this clinical trial is to evaluate the effects of a follow-up-based nursing care protocol-implemented during the perioperative and post-discharge home care processes-on pelvic organ prolapse symptoms, quality of life…
- Trial name
- NCT06631508
- Testing
- Follow-up-based Nursing Care Protocol, Control Group: Routin Care
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Preoperative Anxiety
A Mobile Application for Child-focused Perioperative Education
The investigators developed a child-friendly mobile application to support accessible, interactive patient/caregiver education about pediatric tonsillectomy.
- Trial name
- NCT06054282
- Testing
- "Ready for Tonsillectomy" educational mobile application
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Children's Healthcare of Atlanta
Postoperative Care, Nursing Caries
Management of Thirst, Nursing Care, Postoperative Care
The study was conducted to determine the effect of oral water and ice popsicle on management of thirst in the immediate postoperative period as experimental.
- Trial name
- NCT04070911
- Testing
- WATER, ICE APPLICATION
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Healthy Individuals, Shellac Nail Polish
Effect of Shellac Nail Polish Application on Pulse Oximetry Measurements in Healthy Individuals
The aim of this study was to determine the effect of shellac nail polish application on pulse oximetry measurements in healthy subjects.
- Conditions
- Healthy Individuals, Shellac Nail Polish, Oxygen Saturation, Nursing
- Trial name
- NCT06101641
- Testing
- Shellac nail polish application
- Where
- Turkey (Türkiye)
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Tarsus University
Acupuncture, Ear
Battlefield Acupuncture and Its Use In Multimodal Perioperative Anesthesia Care
The study hypothesis is that perioperative Auricular (battlefield) acupuncture for general surgery and urology cases undergoing general anesthesia will decrease opioid requirements, postoperative pain, the incidence of PONV, and…
- Trial name
- BFA (NCT04615299)
- Testing
- Auricular acupuncture
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Anesthesiology WSU/DMC-NorthStar
Anesthesia
Educating Anesthesia Residents to Improve Perioperative Care for the Elderly
1. The investigators will design, test and implement a education curriculum for anesthesia residents teaching geriatric anesthesiology. 2.
- Trial name
- NCT03008863
- Testing
- Education
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Duke University
Missed Nursing Care, Patient Safety
Perioperative Nursing Workload, Missed Care, and Near-Miss Events
This prospective, single-center observational study examines the relationship between perioperative nursing workload and safety-critical perioperative nursing care in the operating rooms of Agri Training and Research Hospital.
- Conditions
- Missed Nursing Care, Patient Safety, Workload
- Trial name
- NCT07834580
- Testing
- Structured Direct Observation and Workload Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Volkan Gokmen
Surgery
The ImPreSS Trial: Pharmacogenomic Decision Making at Time of Surgery
The study is enrolling adults who are scheduled for either inpatient or outpatient elective surgical procedures at The University of Chicago.
- Trial name
- NCT03729180
- Testing
- Routine Elective Surgery- In patient or out patient elective surgery, Blood test for genetic testing, Drug-genetic Profile
- Where
- United States
- Volunteers
- 1,900 people, healthy volunteers welcome
- Sponsor
- University of Chicago