Clinical trials: Perioperative Fluid Management
Cerebrospinal Fluid Leak
Perioperative CSF Leak Management - an Opinion Study
Cerebrospinal fluid (CSF) leak is a rare condition. When it involves the ventral skull base, a surgical closure may be achieved using endoscopic skull base surgery techniques.
- Trial name
- NCT04124523
- Where
- France
- Volunteers
- 153 people
- Sponsor
- University Hospital, Montpellier
Pancreatic Cancer
Randomized Trial of Restrictive Versus Liberal Perioperative Fluid Management for Patients Undergoing Pancreatic Resection
The purpose of this study is to help us learn what the best amount of fluid is that patients should receive during pancreas surgery.
- Trial name
- NCT01058746
- Testing
- restrictive perioperative fluid management, Liberal perioperative fluid management
- Where
- United States
- Volunteers
- 331 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Fluid Management
Stroke Volume Variation-guided Fluid Infusion in Major Liver Tumour Resection
Studies have demonstrated that the rate of change in stroke volume variation (SVV) can be used to determine the volume of body fluids during major abdominal surgery.
- Trial name
- NCT05361252
- Testing
- SVV-guided fluid management
- Where
- Taiwan
- Volunteers
- 118 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Cancer
Hemodynamic Monitoring in Hepatopancreaticobiliary (HPB) Surgery
This is a pilot study with the primary objective to validate the use of advanced minimally invasive hemodynamic monitoring with the PreSep™ Central Venous Oximetry Catheter, the Vigileo™ monitor, and FloTrac™ sensor for…
- Trial name
- NCT03612687
- Testing
- Minimally invasive hemodynamic monitoring
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Hyperkalaemia Requiring Postoperative Dialysis, Metabolic Acidosis
Perioperative Fluid Management in Patients Receiving Cadaveric Renal Transplants
In this study we want to show that the choice of a balanced type fluid solution for the perioperative fluid management of patients receiving cadaveric renal transplantation results in less occurrence of intra- and postoperative…
- Trial name
- NCT01075750
- Where
- Austria
- Volunteers
- 150 people
- Sponsor
- Medical University of Vienna
Intestinal Obstruction, Intestinal Perforation
Pathophysiology of Perioperative Fluid Management in Emergency Laparotomy
Pathophysiology of perioperative fluid management in patients undergoing emergency laparotomy.
- Conditions
- Intestinal Obstruction, Intestinal Perforation, Anastomotic Leak, Fluid Overload
- Trial name
- NCT03997721
- Where
- Denmark
- Volunteers
- 73 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Perioperative Fluid Management
Comparison of Perioperative Standard Fluid Management and Goal-Directed Fluid Management
To compare the goal-directed fluid therapy based on the data obtained from the hemodynamic monitoring system, which provides continuous CO, SV and SVV measurements through arterial pressure wave with standard fluid therapy in…
- Trial name
- NCT04728178
- Testing
- Crystalloid solution, Colloid solution
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University
Liver Cancer
Clinical Trial of Standard Versus Goal-Directed Perioperative Fluid Management (GDT) for Patients Undergoing Liver Resection
The purpose of this study is to help us learn what is the best amount of fluid to administer to patients during liver surgery. Patients will receive either an amount for this surgery based on weight, blood pressure, heart rate…
- Trial name
- NCT01596283
- Testing
- Standard fluid management, Goal directed fluid therapy with the Edwards EV1000 system
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Fluid Overload, Fluid Loss
Peroperative Fluid Management in Major Gynecological Cancer Surgeries
The aim of this study is to evaluate the effect of perioperative fluid management on postoperative kidney damage in gynecological cancer surgeries.
- Conditions
- Fluid Overload, Fluid Loss, Perioperative/Postoperative Complications, Acute Kidney Injury
- Trial name
- NCT06101498
- Testing
- Akut kidnet injury(AKI)
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Non-Cardiac/ Non-Thoracic Surgery, Abdominal Surgery
Assisted Fluid Management IDE Study
The primary objective of this study is to evaluate the performance of the Acumen™ Assisted Fluid Management (AFM) Feature in its ability to predict a subject's fluid responsiveness.
- Conditions
- Non-Cardiac/ Non-Thoracic Surgery, Abdominal Surgery, Pelvic Surgery, Major Peripheral Vascular Surgery
- Trial name
- AFM (NCT03469570)
- Testing
- EV1000 Clinical Platform with Assisted Fluid Management (AFM) Feature
- Where
- 10 sites in United States
- Volunteers
- 330 people
- Sponsor
- Edwards Lifesciences
Dental Caries
The Incidence of IV Fluid Over-administration in Pediatric Dental Surgeries When Infusion Pumps Are Employed
A prospective, analyst-blinded, randomized control trial to assess the incidence of intravenous (IV) fluid over-administration in the setting of pediatric dental surgeries.
- Trial name
- NCT03312452
- Testing
- Hospira plum pump, Gravity drip device
- Where
- Canada
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Femoral Neck Fractures
the Effects of Perioperative Goal Directed and Conventional Fluid Management on the IVC Collapsibility Index
The investigators aimed to compare the effects of targeted fluid management and traditional fluid management on the inferior vena cava collapsibility index in participants who will undergo proximal femoral surgery.
- Trial name
- NCT05154435
- Testing
- mostcare hemodynamic monitor
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Intraoperative Hypotension, Intraoperative Complications
Comparison of Conventional Fluid Management Protocol With Targeted Pleth Variability Index (PVI) Monitoring Protocol During Total Abdominal Hysterectomy and Bilateral Salpingooferectomy Operation
This study aims to compare the volume management methods performed by using conventional method and PVI monitoring in intraoperative fluid treatment during bilateral salpingo-oophorectomy and total hysterectomy operation.
- Conditions
- Intraoperative Hypotension, Intraoperative Complications, Hypervolemia, Acute Renal Failure
- Trial name
- NCT04775576
- Testing
- Pleth Variability Index, Conventional fluid theraphy, Anesthesia method
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Bladder Cancer
A Prospective Randomized Controlled Clinical Trial of Standard Versus Goal-Directed Perioperative Fluid Management (GDT) for Patients Undergoing Radical Cystectomy
The purpose of this study is to help us learn what is the best amount of fluid to give to patients during bladder surgery in order to avoid delayed bowel function after surgery, which could prolong hospital stay.
- Trial name
- NCT02145871
- Testing
- standard fluid management, fluid management guided by the EV1000
- Where
- 5 sites in United States
- Volunteers
- 282 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Perioperative Fluid Management, Hemodynamic Monitoring
Study Of Ultrasound Windows For Measuring Inferior Vena Cava Changes Before Cardiac Surgery
This research study will compare two ultrasound methods for assessing the inferior vena cava (IVC), a major vein that reflects intravascular fluid status and cardiac function before and after surgery.
- Conditions
- Perioperative Fluid Management, Hemodynamic Monitoring, Inferior Vena Cava Collapsibility Index, Cardiac Surgery Patients
- Trial name
- THRIVE-CARD (NCT07305051)
- Where
- Canada
- Volunteers
- 283 people
- Sponsor
- Sunnybrook Health Sciences Centre
Hypotension Drug-Induced, Anesthesia
Pre-op Fluid Study
Theoretical framework: Hypotension during surgery directly impacts patients' postoperative outcomes and complications. Decrease in blood pressure measurements secondary to anesthetic drugs is an expected scenario in most surgical…
- Trial name
- NCT05079269
- Testing
- Crystalloid Solutions
- Where
- 2 sites in Austria
- Volunteers
- 550 people
- Sponsor
- Medical University of Graz
Perioperative Fluid Management
Comparison of Hemodynamic Results of Two Different Fluid Managements
In the reduction mammoplasty operations performed in the Plastic and Reconstructive surgery operating room in our clinic, the female patient group, who does not have co-morbidities and does not exceed middle age, is followed by…
- Trial name
- NCT05733403
- Testing
- isotonic solution, Noradrenaline
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Hypotension, Anomaly; Venous Return
Perioperative Fluid Management in Morbidly Obese Patients
In bariatric surgery functional and feasible non- or mini-invasive modalities for monitoring, and ideal/lean body weight estimates are addressed to meet up individual variability in hydration needs, and to avoid hyperhydration.
- Conditions
- Hypotension, Anomaly; Venous Return, Dehydration
- Trial name
- NCT01873183
- Testing
- Goal directed fluid therapy
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Umeå University
Mammaplasty, Microsurgery
Perioperative Management of DIEP Flaps
By comparison of two different protocols with diverse fluid/ catecholamine administration limits (fluid restriction vs. catecholamine restriction with target systolic blood pressure > 100 mmHg) the investigators would like to…
- Conditions
- Mammaplasty, Microsurgery, Free Tissue Flaps
- Trial name
- NCT03118024
- Testing
- Crystalloid Solutions, Catecholamines
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Regensburg
Perioperative Care, Hemodynamics
ImPortance of Arterial Measurement Sites (IPAMS) on Intraoperative Hemodynamic Management
The goal of this clinical trial is to demonstrate the importance of arterial pressure measurement sites during major abdominal surgeries.
- Conditions
- Perioperative Care, Hemodynamics, Monitoring Blood Pressure, Arterial Lines
- Trial name
- IPAMS (NCT06982001)
- Testing
- Brachial line guided hemodynamic management, Radial line guided hemodynamic management, Radial line catheterization
- Where
- Canada
- Volunteers
- 204 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal